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The map label for this gene is tyrA [H]

Identifier: 108563751

GI number: 108563751

Start: 1373914

End: 1374753

Strand: Direct

Name: tyrA [H]

Synonym: HPAG1_1326

Alternate gene names: 108563751

Gene position: 1373914-1374753 (Clockwise)

Preceding gene: 108563750

Following gene: 108563755

Centisome position: 86.07

GC content: 42.02

Gene sequence:

>840_bases
TTGAAATTTGGCATGAAAGCAGGCATTATTGGTTTAGGGCTTATGGGGGGGAGTTTAGGGTTGGCTTTGCAAGAATGGGG
GCGTTTTAAAAGCGTTACAGGCTATGATCATAACGCTTTGCATGCTAAATTGGCTTTGACTTTGGGGCTTGTAGATGAGT
GCGTGGAATTTGAAAAGATTTTAGAATGCGATGTGATTTTTTTGGCCATTCCGGTTGAGGGCATCATTGCATGTTTGAAA
AAAATGACTCCCATTAAAAAAAGCGCAACGATTATTGATTTAGGGGGCACTAAAGCACAAATCATTCGCCATATCCCCAA
AAGCATTCGTCAAAATTTCATCGCCGCACACCCCATGTGCGGGACAGAGTTTTATGGCCCTAAAGCGAGCGTTAAGGGGC
TGTATGAAAACGCCCTGGTGATATTGTGCGATTTAGAAGATTCAGGGATTGAGCAAGTAGAGCTCGCTAAAGAAATCTTT
TTAGGCGTTAAAGCGCGCTTGATTAAAATGAAATCTAGCGAGCATGACGCCCATGTGGCTTATATCAGCCATTTACCCCA
TGTTTTGAGCTATGCGTTAGCTAATAGCGTTTTAAAGCAAAACGATCCAGAGATGATTCTATCTTTAGCGGGTGGGGGTT
TTAGAGATATGAGCCGTTTGTCTAAAAGCTCGCCTTTAATGTGGAAAGATATCTTCAAACAAAACCGAGACAATGTCTTA
GAAGCGATTAAAAAATGCGAAAAAGAAATCGCACAAGCTAAGGCGTGGATAGAAAATAACGATTATGAAAGCCTTGCAGA
ATGGATGGCGCAAGCGAACAAACTCCAGGAGTTCATGTAA

Upstream 100 bases:

>100_bases
ATTACGAAAGGGATTTAGATGAAATCCCTGCTGAAGTGCGAGAGAATTTAAACATCGTTGCGGTGAAAAACATCGCTGAA
GTGTTGGAAAAAACTTTGCT

Downstream 100 bases:

>100_bases
AATAGTTTAAAATTTGTATATAGAAAATAACGATTGTTGTTTTTAGAGTTGCGAGGAGCAGGCAATAATCGTTTTTATCC
CATTTCTCCAACACCTATGA

Product: prephenate dehydrogenase

Products: NA

Alternate protein names: PDH [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MKFGMKAGIIGLGLMGGSLGLALQEWGRFKSVTGYDHNALHAKLALTLGLVDECVEFEKILECDVIFLAIPVEGIIACLK
KMTPIKKSATIIDLGGTKAQIIRHIPKSIRQNFIAAHPMCGTEFYGPKASVKGLYENALVILCDLEDSGIEQVELAKEIF
LGVKARLIKMKSSEHDAHVAYISHLPHVLSYALANSVLKQNDPEMILSLAGGGFRDMSRLSKSSPLMWKDIFKQNRDNVL
EAIKKCEKEIAQAKAWIENNDYESLAEWMAQANKLQEFM

Sequences:

>Translated_279_residues
MKFGMKAGIIGLGLMGGSLGLALQEWGRFKSVTGYDHNALHAKLALTLGLVDECVEFEKILECDVIFLAIPVEGIIACLK
KMTPIKKSATIIDLGGTKAQIIRHIPKSIRQNFIAAHPMCGTEFYGPKASVKGLYENALVILCDLEDSGIEQVELAKEIF
LGVKARLIKMKSSEHDAHVAYISHLPHVLSYALANSVLKQNDPEMILSLAGGGFRDMSRLSKSSPLMWKDIFKQNRDNVL
EAIKKCEKEIAQAKAWIENNDYESLAEWMAQANKLQEFM
>Mature_279_residues
MKFGMKAGIIGLGLMGGSLGLALQEWGRFKSVTGYDHNALHAKLALTLGLVDECVEFEKILECDVIFLAIPVEGIIACLK
KMTPIKKSATIIDLGGTKAQIIRHIPKSIRQNFIAAHPMCGTEFYGPKASVKGLYENALVILCDLEDSGIEQVELAKEIF
LGVKARLIKMKSSEHDAHVAYISHLPHVLSYALANSVLKQNDPEMILSLAGGGFRDMSRLSKSSPLMWKDIFKQNRDNVL
EAIKKCEKEIAQAKAWIENNDYESLAEWMAQANKLQEFM

Specific function: Tyrosine biosynthesis [C]

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate/arogenate dehydrogenase domain [H]

Homologues:

None

Paralogues:

None

Copy number: 500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR016040
- InterPro:   IPR003099 [H]

Pfam domain/function: PF02153 PDH [H]

EC number: =1.3.1.12 [H]

Molecular weight: Translated: 30906; Mature: 30906

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFGMKAGIIGLGLMGGSLGLALQEWGRFKSVTGYDHNALHAKLALTLGLVDECVEFEKI
CCCCCHHCHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LECDVIFLAIPVEGIIACLKKMTPIKKSATIIDLGGTKAQIIRHIPKSIRQNFIAAHPMC
HHHCCEEEEECHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCC
GTEFYGPKASVKGLYENALVILCDLEDSGIEQVELAKEIFLGVKARLIKMKSSEHDAHVA
CCCCCCCCHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
YISHLPHVLSYALANSVLKQNDPEMILSLAGGGFRDMSRLSKSSPLMWKDIFKQNRDNVL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHCCHHHHH
EAIKKCEKEIAQAKAWIENNDYESLAEWMAQANKLQEFM
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFGMKAGIIGLGLMGGSLGLALQEWGRFKSVTGYDHNALHAKLALTLGLVDECVEFEKI
CCCCCHHCHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LECDVIFLAIPVEGIIACLKKMTPIKKSATIIDLGGTKAQIIRHIPKSIRQNFIAAHPMC
HHHCCEEEEECHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCC
GTEFYGPKASVKGLYENALVILCDLEDSGIEQVELAKEIFLGVKARLIKMKSSEHDAHVA
CCCCCCCCHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
YISHLPHVLSYALANSVLKQNDPEMILSLAGGGFRDMSRLSKSSPLMWKDIFKQNRDNVL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHCCHHHHH
EAIKKCEKEIAQAKAWIENNDYESLAEWMAQANKLQEFM
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA