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The map label for this gene is mreB [H]

Identifier: 108563743

GI number: 108563743

Start: 1365991

End: 1367034

Strand: Reverse

Name: mreB [H]

Synonym: HPAG1_1318

Alternate gene names: 108563743

Gene position: 1367034-1365991 (Counterclockwise)

Preceding gene: 108563744

Following gene: 108563742

Centisome position: 85.63

GC content: 47.03

Gene sequence:

>1044_bases
ATGATTTTTAGCAAATTGATCGGTTTGTTTTCGCATGATATTGCCATAGATTTAGGCACGGCTAACACGATCGTGTTAGT
CAAAGGGCAGGGCATTATTATCAATGAACCTTCTATTGTGGCGGTGCGCATGGGATTGTTTGATTCTAAAGCTTATGATA
TTTTAGCAGTGGGGAGCGAGGCTAAGGAAATGCTAGGCAAAACCCCTAACAGCATCAGAGCGATTCGCCCCATGAAAGAT
GGCGTGATCGCCGATTATGACATTACCGCTAAAATGATCCGCTACTTTATTGAAAAAGCGCACAAACGAAAAACATGGAT
CCGCCCGCGCATCATGGTATGCGTGCCTTATGGGTTGACGAGCGTGGAAAGGAATGCGGTTAAAGAGAGCGCTTTAAGCG
CTGGGGCTAGAGAAGTCTTTTTGATTGAAGAGCCTATGGCAGCCGCGATCGGGGCAGGCTTACCGGTGAAAGAACCGCAA
GGGAGTTTGATTGTAGATATTGGCGGCGGCACGACTGAAATTGGCGTGATTAGCCTTGGGGGGTTAGTCATTTCTAAAAG
CATTAGAGTGGCCGGGGATAAATTGGATCAAAGCATCGTGGAATACATCCGCAAAAAATTCAATCTGTTGATAGGGGAGC
GCACCGGCGAAGAGATTAAGATTGAAATCGGTTGCGCGATCAAATTGGATCCGCCTCTTACCATGGAAGTGTCAGGGAGG
GATCAAGTGAGCGGGCTGTTGCACACGATTGAATTGAGCTCTGATGATGTGTTTGAAGCCATTAAAGATCAGGTGAGGGA
AATCTCTAGCGCTTTAAGGAGCGTGCTTGAAGAAGTGAAGCCGGATTTAGCGAAAGACATTGTGCAAAATGGCGTGGTGC
TTACCGGCGGTGGGGCTTTGATTAAGGGCTTAGACAAGTATTTAAGCGATATGGTTAAACTCCCTGTGTATGTGGGCGAT
GAGCCTTTATTGGCCGTGGCCAAAGGCACAGGGGAAGCCATACAAGATTTGGATTTACTCAGCCGTGTGGGTTTTAGTGA
ATAA

Upstream 100 bases:

>100_bases
TTTGAAACAGGCTGAACCTTTGATCATTGCTAAAACGCATTCTAAAATTCTTCCTTAAGGAACACGCTTATAAATTTAAC
GATAAAGGATTAGAAAGGGC

Downstream 100 bases:

>100_bases
TGCATGCGTTTTTATTTTAAATTCCTTTGGCTTTTAGGGATTTTTCTTATTTTTTATTTTTTAGATATTAAAGGCAGTTC
TTCTTATATCAGCGACCGGA

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MIFSKLIGLFSHDIAIDLGTANTIVLVKGQGIIINEPSIVAVRMGLFDSKAYDILAVGSEAKEMLGKTPNSIRAIRPMKD
GVIADYDITAKMIRYFIEKAHKRKTWIRPRIMVCVPYGLTSVERNAVKESALSAGAREVFLIEEPMAAAIGAGLPVKEPQ
GSLIVDIGGGTTEIGVISLGGLVISKSIRVAGDKLDQSIVEYIRKKFNLLIGERTGEEIKIEIGCAIKLDPPLTMEVSGR
DQVSGLLHTIELSSDDVFEAIKDQVREISSALRSVLEEVKPDLAKDIVQNGVVLTGGGALIKGLDKYLSDMVKLPVYVGD
EPLLAVAKGTGEAIQDLDLLSRVGFSE

Sequences:

>Translated_347_residues
MIFSKLIGLFSHDIAIDLGTANTIVLVKGQGIIINEPSIVAVRMGLFDSKAYDILAVGSEAKEMLGKTPNSIRAIRPMKD
GVIADYDITAKMIRYFIEKAHKRKTWIRPRIMVCVPYGLTSVERNAVKESALSAGAREVFLIEEPMAAAIGAGLPVKEPQ
GSLIVDIGGGTTEIGVISLGGLVISKSIRVAGDKLDQSIVEYIRKKFNLLIGERTGEEIKIEIGCAIKLDPPLTMEVSGR
DQVSGLLHTIELSSDDVFEAIKDQVREISSALRSVLEEVKPDLAKDIVQNGVVLTGGGALIKGLDKYLSDMVKLPVYVGD
EPLLAVAKGTGEAIQDLDLLSRVGFSE
>Mature_347_residues
MIFSKLIGLFSHDIAIDLGTANTIVLVKGQGIIINEPSIVAVRMGLFDSKAYDILAVGSEAKEMLGKTPNSIRAIRPMKD
GVIADYDITAKMIRYFIEKAHKRKTWIRPRIMVCVPYGLTSVERNAVKESALSAGAREVFLIEEPMAAAIGAGLPVKEPQ
GSLIVDIGGGTTEIGVISLGGLVISKSIRVAGDKLDQSIVEYIRKKFNLLIGERTGEEIKIEIGCAIKLDPPLTMEVSGR
DQVSGLLHTIELSSDDVFEAIKDQVREISSALRSVLEEVKPDLAKDIVQNGVVLTGGGALIKGLDKYLSDMVKLPVYVGD
EPLLAVAKGTGEAIQDLDLLSRVGFSE

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=348, Percent_Identity=51.7241379310345, Blast_Score=356, Evalue=1e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 37340; Mature: 37340

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFSKLIGLFSHDIAIDLGTANTIVLVKGQGIIINEPSIVAVRMGLFDSKAYDILAVGSE
CHHHHHHHHHHCCEEEEECCCCEEEEEECCEEEEECCCEEEEEECCCCCCCEEEEEECHH
AKEMLGKTPNSIRAIRPMKDGVIADYDITAKMIRYFIEKAHKRKTWIRPRIMVCVPYGLT
HHHHHCCCCCHHEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
SVERNAVKESALSAGAREVFLIEEPMAAAIGAGLPVKEPQGSLIVDIGGGTTEIGVISLG
HHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEEC
GLVISKSIRVAGDKLDQSIVEYIRKKFNLLIGERTGEEIKIEIGCAIKLDPPLTMEVSGR
CCCEECCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEEEEEEEECCCEEEEECCC
DQVSGLLHTIELSSDDVFEAIKDQVREISSALRSVLEEVKPDLAKDIVQNGVVLTGGGAL
HHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCEEEECCHHH
IKGLDKYLSDMVKLPVYVGDEPLLAVAKGTGEAIQDLDLLSRVGFSE
HHHHHHHHHHHHHCCEEECCCCEEEEECCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIFSKLIGLFSHDIAIDLGTANTIVLVKGQGIIINEPSIVAVRMGLFDSKAYDILAVGSE
CHHHHHHHHHHCCEEEEECCCCEEEEEECCEEEEECCCEEEEEECCCCCCCEEEEEECHH
AKEMLGKTPNSIRAIRPMKDGVIADYDITAKMIRYFIEKAHKRKTWIRPRIMVCVPYGLT
HHHHHCCCCCHHEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
SVERNAVKESALSAGAREVFLIEEPMAAAIGAGLPVKEPQGSLIVDIGGGTTEIGVISLG
HHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEEC
GLVISKSIRVAGDKLDQSIVEYIRKKFNLLIGERTGEEIKIEIGCAIKLDPPLTMEVSGR
CCCEECCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEEEEEEEECCCEEEEECCC
DQVSGLLHTIELSSDDVFEAIKDQVREISSALRSVLEEVKPDLAKDIVQNGVVLTGGGAL
HHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCEEEECCHHH
IKGLDKYLSDMVKLPVYVGDEPLLAVAKGTGEAIQDLDLLSRVGFSE
HHHHHHHHHHHHHCCEEECCCCEEEEECCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]