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The map label for this gene is hcpE [H]

Identifier: 108563480

GI number: 108563480

Start: 1112089

End: 1112859

Strand: Reverse

Name: hcpE [H]

Synonym: HPAG1_1055

Alternate gene names: 108563480

Gene position: 1112859-1112089 (Counterclockwise)

Preceding gene: 108563481

Following gene: 108563479

Centisome position: 69.71

GC content: 38.0

Gene sequence:

>771_bases
ATGGGATACGCAAGCAAATTAGCCTTGAAGATTTGTTTGGCAAGTTTATGTTTATTTAGCGCTCTTGGTGCAGAACACCT
TGAACAAAAAGGGAATTTTATTTATAAAGGGGAGGAAGCCTATAATAATAAGGAGTATGAGCGAGCGGCTTCTTTTTATA
AGAGCGCTATTAAAAATGGCGAGCCGCTTGCTTATGTTCTTTTAGGGATCATGTATGAAAATGGTAGGGGTGTGCCTAAA
GATTACAAGAAAGCGGCTGAATATTTTCAAAAAGCGGTTGATAACGATATACCTAGAGGGTATAATAATTTAGGCGTGAT
GTATAAAGAGGGTAGGGGCGTTCCTAAAGATGAAAAGAAAGCCGTGGAGTATTTTAGAATAGCTACAGAGAAAGGCTATA
CTAACGCCTATATCAACTTAGGCATCATGTATATGGAGGGTAGGGGCGTTCCAAGCAACTATGTGAAAGCGACAGAGTGC
TTTAGAAAAGCGATGCATAAGGGTAATGTAGAAGCTTATATCCTTTTAGGGGATATTTATTATAGTGGGAATGATCAATT
GGGGATTGAGCCAGACAAAGATAAGGCTATTGTCTATTATAAAATGGCGGCTGATATGAGTTCTTCTAGAGCTTATGAAG
GGTTAGCAGAGTCTTATCAGTATGGGTTAGGTGTGGAAAAAGATAAGAAAAAGGCTGAAGAATACATGCAAAAAGCATGC
GATTTTGACATTGATAAAAATTGTAAGAAAAAGAACACTTCAAGCCGATAA

Upstream 100 bases:

>100_bases
GTTTGAGAATGTTTGCTGGTTTTAGAACGCATGCAGTTTCTTTTTTAAGATTAATAGCCATTGACATTATGTTTGATCTT
ATTAAAGCAGAGGAGTAATA

Downstream 100 bases:

>100_bases
TTCTCAAACTTGGACTTGATTCAAGGATTTTTTATTTTGTGCTAAGTAGCGTGTTTTTTGAGCAATTGATTTGAAGCGAC
AGATTAAAGATATTGCATTT

Product: cysteine-rich protein X

Products: NA

Alternate protein names: Cysteine-rich protein E [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MGYASKLALKICLASLCLFSALGAEHLEQKGNFIYKGEEAYNNKEYERAASFYKSAIKNGEPLAYVLLGIMYENGRGVPK
DYKKAAEYFQKAVDNDIPRGYNNLGVMYKEGRGVPKDEKKAVEYFRIATEKGYTNAYINLGIMYMEGRGVPSNYVKATEC
FRKAMHKGNVEAYILLGDIYYSGNDQLGIEPDKDKAIVYYKMAADMSSSRAYEGLAESYQYGLGVEKDKKKAEEYMQKAC
DFDIDKNCKKKNTSSR

Sequences:

>Translated_256_residues
MGYASKLALKICLASLCLFSALGAEHLEQKGNFIYKGEEAYNNKEYERAASFYKSAIKNGEPLAYVLLGIMYENGRGVPK
DYKKAAEYFQKAVDNDIPRGYNNLGVMYKEGRGVPKDEKKAVEYFRIATEKGYTNAYINLGIMYMEGRGVPSNYVKATEC
FRKAMHKGNVEAYILLGDIYYSGNDQLGIEPDKDKAIVYYKMAADMSSSRAYEGLAESYQYGLGVEKDKKKAEEYMQKAC
DFDIDKNCKKKNTSSR
>Mature_255_residues
GYASKLALKICLASLCLFSALGAEHLEQKGNFIYKGEEAYNNKEYERAASFYKSAIKNGEPLAYVLLGIMYENGRGVPKD
YKKAAEYFQKAVDNDIPRGYNNLGVMYKEGRGVPKDEKKAVEYFRIATEKGYTNAYINLGIMYMEGRGVPSNYVKATECF
RKAMHKGNVEAYILLGDIYYSGNDQLGIEPDKDKAIVYYKMAADMSSSRAYEGLAESYQYGLGVEKDKKKAEEYMQKACD
FDIDKNCKKKNTSSR

Specific function: May hydrolyze 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 8 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI151301150, Length=193, Percent_Identity=35.2331606217617, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI19923669, Length=197, Percent_Identity=31.4720812182741, Blast_Score=93, Evalue=3e-19,
Organism=Escherichia coli, GI87081769, Length=204, Percent_Identity=32.3529411764706, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1786867, Length=109, Percent_Identity=32.1100917431193, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17563256, Length=179, Percent_Identity=30.7262569832402, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355295, Length=227, Percent_Identity=30.3964757709251, Blast_Score=87, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006597
- InterPro:   IPR011990 [H]

Pfam domain/function: PF08238 Sel1 [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 28931; Mature: 28800

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYASKLALKICLASLCLFSALGAEHLEQKGNFIYKGEEAYNNKEYERAASFYKSAIKNG
CCHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCEEEECHHHHCCHHHHHHHHHHHHHHCCC
EPLAYVLLGIMYENGRGVPKDYKKAAEYFQKAVDNDIPRGYNNLGVMYKEGRGVPKDEKK
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCHHHH
AVEYFRIATEKGYTNAYINLGIMYMEGRGVPSNYVKATECFRKAMHKGNVEAYILLGDIY
HHHHHHHHHCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEE
YSGNDQLGIEPDKDKAIVYYKMAADMSSSRAYEGLAESYQYGLGVEKDKKKAEEYMQKAC
ECCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
DFDIDKNCKKKNTSSR
CCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GYASKLALKICLASLCLFSALGAEHLEQKGNFIYKGEEAYNNKEYERAASFYKSAIKNG
CHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCEEEECHHHHCCHHHHHHHHHHHHHHCCC
EPLAYVLLGIMYENGRGVPKDYKKAAEYFQKAVDNDIPRGYNNLGVMYKEGRGVPKDEKK
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCHHHH
AVEYFRIATEKGYTNAYINLGIMYMEGRGVPSNYVKATECFRKAMHKGNVEAYILLGDIY
HHHHHHHHHCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEE
YSGNDQLGIEPDKDKAIVYYKMAADMSSSRAYEGLAESYQYGLGVEKDKKKAEEYMQKAC
ECCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
DFDIDKNCKKKNTSSR
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]