Click here to switch to the map view.

The map label for this gene is exoB [H]

Identifier: 108563458

GI number: 108563458

Start: 1086548

End: 1087582

Strand: Reverse

Name: exoB [H]

Synonym: HPAG1_1033

Alternate gene names: 108563458

Gene position: 1087582-1086548 (Counterclockwise)

Preceding gene: 108563461

Following gene: 108563445

Centisome position: 68.13

GC content: 39.42

Gene sequence:

>1035_bases
ATGGCATTATTATTCACAGGAGCGTGCGGGTATATAGGCTCGCATACCGCAAGGGCGTTTTTAGAAAAAACCAAAGAAAA
CATCATTATTGTAGATGACTTAAGCACCGGTTTTTTAGAGCATATCAAAGCGTTAGAGCGTTACTACCCTAATAGGGTTA
CTTTTATTCAAGCGAATTTGAATGAAACGCAAAAATTAGACGCCTTTTTAAATAAACAACAGCTAAAAGATCCCATTGAA
GCTATTTTGCACTTTGGGGCTAAAATCTCAGTAGAAGAATCCACGCGTTTGCCTTTAGAATACTACACCAACAACACGCT
CAACACTTTAGAGCTTGTCAAACTTTGCTTAAAACATGCAATCAAGCGTTTTATTTTTTCTTCCACAGCTGCGGTTTATG
GCGAGTCTGATTTTAGCTTGAATGAAGAAAGCCCCTTAAACCCCATTAATCCTTATGGAGCGTCTAAAATGATGAGCGAA
AGGATTTTGTTAGACACTTCTAAAATAGCGGATTTTAAATGCGTTATTTTGCGCTATTTCAATGTGGCTGGGGCATGCAT
GCACAATGATTATACCACCCCCTACACGCTAGGCCAGCGCACGCTCAACGCCACGCATTTAATCAAAATCGCATGCGAAT
GCGCAGTGGGGAAAAGGAAAAAAATGGGGATTTTTGGCACTAACTACCCCACAAGAGATGGCACTTGCATTAGGGATTAT
ATCCATGTAGATGATTTGGCTAACGCGCATTTAGCGAGCTATCAAACCCTTTTAGAAAAAAATAAGAGCGAGATTTATAA
TGTCGGCTACAATCAAGGCCATAGCGTGAAAGAAGTGATTAACAAGGTTAAAGAAATCTCAAACAACGATTTTTTAGTGG
AAATTCTAGACAAACGACAGGGCGATCCAGCAAGCCTTATTGCCAATAACGCTAAAATCTTACAAAACACCCCTTTCAAA
CCCCTTTATAACAACCTAGACACCATTATCAAAAGCGCTCTAGATTGGGAAGAACACCTTTTAAGATTTCAATAA

Upstream 100 bases:

>100_bases
AGATGAAATTATAGGTTAAACTTTCTTAAAAAATCCTTAAACAATAAATGGGATTAAGATGTTATAATAGTTGTCATTTT
TTCATTTTAAAAGGGGTTTT

Downstream 100 bases:

>100_bases
TACACCCTGTGCAAATACAAGCCATCAGCCATTATGGGCGTTCTTATGGTGGCTTTGATGTTGTGGATTTGCATTTCAAT
TTCAGCGAGCGTGATTTTTT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MALLFTGACGYIGSHTARAFLEKTKENIIIVDDLSTGFLEHIKALERYYPNRVTFIQANLNETQKLDAFLNKQQLKDPIE
AILHFGAKISVEESTRLPLEYYTNNTLNTLELVKLCLKHAIKRFIFSSTAAVYGESDFSLNEESPLNPINPYGASKMMSE
RILLDTSKIADFKCVILRYFNVAGACMHNDYTTPYTLGQRTLNATHLIKIACECAVGKRKKMGIFGTNYPTRDGTCIRDY
IHVDDLANAHLASYQTLLEKNKSEIYNVGYNQGHSVKEVINKVKEISNNDFLVEILDKRQGDPASLIANNAKILQNTPFK
PLYNNLDTIIKSALDWEEHLLRFQ

Sequences:

>Translated_344_residues
MALLFTGACGYIGSHTARAFLEKTKENIIIVDDLSTGFLEHIKALERYYPNRVTFIQANLNETQKLDAFLNKQQLKDPIE
AILHFGAKISVEESTRLPLEYYTNNTLNTLELVKLCLKHAIKRFIFSSTAAVYGESDFSLNEESPLNPINPYGASKMMSE
RILLDTSKIADFKCVILRYFNVAGACMHNDYTTPYTLGQRTLNATHLIKIACECAVGKRKKMGIFGTNYPTRDGTCIRDY
IHVDDLANAHLASYQTLLEKNKSEIYNVGYNQGHSVKEVINKVKEISNNDFLVEILDKRQGDPASLIANNAKILQNTPFK
PLYNNLDTIIKSALDWEEHLLRFQ
>Mature_343_residues
ALLFTGACGYIGSHTARAFLEKTKENIIIVDDLSTGFLEHIKALERYYPNRVTFIQANLNETQKLDAFLNKQQLKDPIEA
ILHFGAKISVEESTRLPLEYYTNNTLNTLELVKLCLKHAIKRFIFSSTAAVYGESDFSLNEESPLNPINPYGASKMMSER
ILLDTSKIADFKCVILRYFNVAGACMHNDYTTPYTLGQRTLNATHLIKIACECAVGKRKKMGIFGTNYPTRDGTCIRDYI
HVDDLANAHLASYQTLLEKNKSEIYNVGYNQGHSVKEVINKVKEISNNDFLVEILDKRQGDPASLIANNAKILQNTPFKP
LYNNLDTIIKSALDWEEHLLRFQ

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=351, Percent_Identity=30.4843304843305, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI56118217, Length=351, Percent_Identity=30.4843304843305, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI189083684, Length=351, Percent_Identity=30.4843304843305, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI7657641, Length=306, Percent_Identity=28.1045751633987, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1786974, Length=341, Percent_Identity=33.4310850439883, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1790049, Length=286, Percent_Identity=26.5734265734266, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788353, Length=324, Percent_Identity=25.3086419753086, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71982035, Length=318, Percent_Identity=34.5911949685535, Blast_Score=171, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI71982038, Length=320, Percent_Identity=34.375, Blast_Score=170, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI17568069, Length=277, Percent_Identity=28.5198555956679, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=318, Percent_Identity=35.5345911949685, Blast_Score=181, Evalue=1e-46,
Organism=Drosophila melanogaster, GI19923002, Length=321, Percent_Identity=31.7757009345794, Blast_Score=157, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 38986; Mature: 38855

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLFTGACGYIGSHTARAFLEKTKENIIIVDDLSTGFLEHIKALERYYPNRVTFIQANL
CEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECC
NETQKLDAFLNKQQLKDPIEAILHFGAKISVEESTRLPLEYYTNNTLNTLELVKLCLKHA
CHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHH
IKRFIFSSTAAVYGESDFSLNEESPLNPINPYGASKMMSERILLDTSKIADFKCVILRYF
HHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEHHHHCHHHHHHHHHH
NVAGACMHNDYTTPYTLGQRTLNATHLIKIACECAVGKRKKMGIFGTNYPTRDGTCIRDY
HHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCHHHHH
IHVDDLANAHLASYQTLLEKNKSEIYNVGYNQGHSVKEVINKVKEISNNDFLVEILDKRQ
HHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHCC
GDPASLIANNAKILQNTPFKPLYNNLDTIIKSALDWEEHLLRFQ
CCCHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHCCC
>Mature Secondary Structure 
ALLFTGACGYIGSHTARAFLEKTKENIIIVDDLSTGFLEHIKALERYYPNRVTFIQANL
EEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECC
NETQKLDAFLNKQQLKDPIEAILHFGAKISVEESTRLPLEYYTNNTLNTLELVKLCLKHA
CHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHH
IKRFIFSSTAAVYGESDFSLNEESPLNPINPYGASKMMSERILLDTSKIADFKCVILRYF
HHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEHHHHCHHHHHHHHHH
NVAGACMHNDYTTPYTLGQRTLNATHLIKIACECAVGKRKKMGIFGTNYPTRDGTCIRDY
HHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCHHHHH
IHVDDLANAHLASYQTLLEKNKSEIYNVGYNQGHSVKEVINKVKEISNNDFLVEILDKRQ
HHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHCC
GDPASLIANNAKILQNTPFKPLYNNLDTIIKSALDWEEHLLRFQ
CCCHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]