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The map label for this gene is hemN [H]

Identifier: 108563075

GI number: 108563075

Start: 676934

End: 678307

Strand: Direct

Name: hemN [H]

Synonym: HPAG1_0650

Alternate gene names: 108563075

Gene position: 676934-678307 (Clockwise)

Preceding gene: 108563074

Following gene: 108563076

Centisome position: 42.4

GC content: 38.86

Gene sequence:

>1374_bases
ATGCAAACCATTGATTTTGAAAAATTTTCACAATATTCCAAGCCCGGCCCACGATACACTAGCTACCCCACAGCGGTGGA
ATTTAAAGAAAATTTTAATGAAGAGAGCTTGAAAACAGCATTTTTTAACCATGACAACCTCAAAAACCCCATGCCTTTAT
CGCTTTATACGCATTTGCCTTTTTGTCGTAGTGCATGTTATTTTTGCGCTTGTTCAGTCATTTACACGAGCTTAGAAGAG
AAAAAAACCCGCTATATCAGCTACCTTAAAAAAGAACTCGCTCTTTTAAAAAATGCGATGGATACCAACAGAGAAGTGGC
GCAATTCCACTATGGAGGCGGCACGCCGACCTTTTTTTCGCCCATTCAATTAGATGAAATCACCCAAAGCATTCAAGAAG
TTTTCCCTAATTTCAGCAAAGATATTGAAATGAGTTGTGAGATTGATCCTAGGCATTTCACTAAAGAACACATGCAAACC
TTGTTTGATAGGGGGTTTAACCGCTTGAGTTTTGGGGTGCAGGATTTTGATTTTGAGGTTCAAAAAGCCATTCACAGGAT
CCAGCCTTTTGAAATGGTTCAAGAATCCGTGAAGCTCGCTAGAGATTACGGCATCAAATCCATTAATTTTGATTTGATTT
ATGGCTTACCCAACCAGACTAAAGAGAGTTTTTTAAAAACTTTGGAATGGGTTTTGAAACTAAATCCGGACCGATTAGCG
GTGTTTAATTACGCGCATGTGCCTTGGGTGAAAAAAACGATGCGTAAAATTGATGAAACCTTATTGCCAAGCCCTAGAGA
CAAGCTAGAGATTTTAGAATCCCTTATTAGTTTTTTAGAAAAAGCCAATTACCAAATGATAGGCATGGATCATTTCGCTA
AAAGCGATAATGAATTGTATCTGGCCCTTCAAAAGGCGGAGTTACGGCGTAATTTTCAAGGCTATACCACGAAAAAATTC
ACTCAAACCATTGGCATTGGCGTTACAAGCATTGGCGAAGGGAGCGATTATTACACGCAAAATTATAAAGATTTGCACCA
CTATGAAAAAGCCCTTGATTTGGGGCATTTACCGGTAGAAAGGGGTGTAGCGCTCAGTCAAGAAGATGTGTTAAGAAAGG
AAGTCATCATGCAAATGATGAGCAATTTAAAACTGGATTACTCTAAGATTGAAGAAAAATTTTCTGTTGATTTTAAAGCG
CATTTTAAAAAAGAATTAGAAAAATTAAAGCCTTATGAAGAAGCGGGCTTGCTTGTTTTTAACCCTAAAGGCTTTGAGAT
GACTAGAACAGGGGGCATGCTCGTAAGAAACATGGCCATGGAGTTTGACGCGTATTTGCGTGGGGGCGAAAAACATTTCA
GTAAAACGCTATGA

Upstream 100 bases:

>100_bases
ACCCGAATTTATTCTTTAATTTTGACAACATGTTCAAACAACCCCCTTTCAATGAGAATAATTTTGAAAATTTTGACAAC
AGCGATGAGGAAAATTTTTA

Downstream 100 bases:

>100_bases
ATGAAAATGTTAATGGAAATATTTTTGAAGAAGTAGGGGACGCTTGCGTTAAATGCGCTAAATGCGTGCCAGGTTGCACG
ATATATCGCATTCATAAGGA

Product: coproporphyrinogen III oxidase

Products: NA

Alternate protein names: Coprogen oxidase; Coproporphyrinogenase [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MQTIDFEKFSQYSKPGPRYTSYPTAVEFKENFNEESLKTAFFNHDNLKNPMPLSLYTHLPFCRSACYFCACSVIYTSLEE
KKTRYISYLKKELALLKNAMDTNREVAQFHYGGGTPTFFSPIQLDEITQSIQEVFPNFSKDIEMSCEIDPRHFTKEHMQT
LFDRGFNRLSFGVQDFDFEVQKAIHRIQPFEMVQESVKLARDYGIKSINFDLIYGLPNQTKESFLKTLEWVLKLNPDRLA
VFNYAHVPWVKKTMRKIDETLLPSPRDKLEILESLISFLEKANYQMIGMDHFAKSDNELYLALQKAELRRNFQGYTTKKF
TQTIGIGVTSIGEGSDYYTQNYKDLHHYEKALDLGHLPVERGVALSQEDVLRKEVIMQMMSNLKLDYSKIEEKFSVDFKA
HFKKELEKLKPYEEAGLLVFNPKGFEMTRTGGMLVRNMAMEFDAYLRGGEKHFSKTL

Sequences:

>Translated_457_residues
MQTIDFEKFSQYSKPGPRYTSYPTAVEFKENFNEESLKTAFFNHDNLKNPMPLSLYTHLPFCRSACYFCACSVIYTSLEE
KKTRYISYLKKELALLKNAMDTNREVAQFHYGGGTPTFFSPIQLDEITQSIQEVFPNFSKDIEMSCEIDPRHFTKEHMQT
LFDRGFNRLSFGVQDFDFEVQKAIHRIQPFEMVQESVKLARDYGIKSINFDLIYGLPNQTKESFLKTLEWVLKLNPDRLA
VFNYAHVPWVKKTMRKIDETLLPSPRDKLEILESLISFLEKANYQMIGMDHFAKSDNELYLALQKAELRRNFQGYTTKKF
TQTIGIGVTSIGEGSDYYTQNYKDLHHYEKALDLGHLPVERGVALSQEDVLRKEVIMQMMSNLKLDYSKIEEKFSVDFKA
HFKKELEKLKPYEEAGLLVFNPKGFEMTRTGGMLVRNMAMEFDAYLRGGEKHFSKTL
>Mature_457_residues
MQTIDFEKFSQYSKPGPRYTSYPTAVEFKENFNEESLKTAFFNHDNLKNPMPLSLYTHLPFCRSACYFCACSVIYTSLEE
KKTRYISYLKKELALLKNAMDTNREVAQFHYGGGTPTFFSPIQLDEITQSIQEVFPNFSKDIEMSCEIDPRHFTKEHMQT
LFDRGFNRLSFGVQDFDFEVQKAIHRIQPFEMVQESVKLARDYGIKSINFDLIYGLPNQTKESFLKTLEWVLKLNPDRLA
VFNYAHVPWVKKTMRKIDETLLPSPRDKLEILESLISFLEKANYQMIGMDHFAKSDNELYLALQKAELRRNFQGYTTKKF
TQTIGIGVTSIGEGSDYYTQNYKDLHHYEKALDLGHLPVERGVALSQEDVLRKEVIMQMMSNLKLDYSKIEEKFSVDFKA
HFKKELEKLKPYEEAGLLVFNPKGFEMTRTGGMLVRNMAMEFDAYLRGGEKHFSKTL

Specific function: Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX [H]

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Escherichia coli, GI87082341, Length=461, Percent_Identity=42.7331887201735, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI1789325, Length=282, Percent_Identity=28.0141843971631, Blast_Score=108, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004558
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: =1.3.99.22 [H]

Molecular weight: Translated: 53342; Mature: 53342

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTIDFEKFSQYSKPGPRYTSYPTAVEFKENFNEESLKTAFFNHDNLKNPMPLSLYTHLP
CCCCCHHHHHHCCCCCCCCCCCCCEEHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHCCH
FCRSACYFCACSVIYTSLEEKKTRYISYLKKELALLKNAMDTNREVAQFHYGGGTPTFFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCCCCC
PIQLDEITQSIQEVFPNFSKDIEMSCEIDPRHFTKEHMQTLFDRGFNRLSFGVQDFDFEV
CCCHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHH
QKAIHRIQPFEMVQESVKLARDYGIKSINFDLIYGLPNQTKESFLKTLEWVLKLNPDRLA
HHHHHHCCHHHHHHHHHHHHHHCCCCEECEEEEECCCCHHHHHHHHHHHHHHHCCCCCEE
VFNYAHVPWVKKTMRKIDETLLPSPRDKLEILESLISFLEKANYQMIGMDHFAKSDNELY
EEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEHHHHCCCCCCEE
LALQKAELRRNFQGYTTKKFTQTIGIGVTSIGEGSDYYTQNYKDLHHYEKALDLGHLPVE
EEEEHHHHHHCCCCCCHHHHHHHHCCCEEECCCCCCHHHCCHHHHHHHHHHHHCCCCCHH
RGVALSQEDVLRKEVIMQMMSNLKLDYSKIEEKFSVDFKAHFKKELEKLKPYEEAGLLVF
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCHHHCCEEEE
NPKGFEMTRTGGMLVRNMAMEFDAYLRGGEKHFSKTL
CCCCCEEECCCHHHHHHHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure
MQTIDFEKFSQYSKPGPRYTSYPTAVEFKENFNEESLKTAFFNHDNLKNPMPLSLYTHLP
CCCCCHHHHHHCCCCCCCCCCCCCEEHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHCCH
FCRSACYFCACSVIYTSLEEKKTRYISYLKKELALLKNAMDTNREVAQFHYGGGTPTFFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCCCCC
PIQLDEITQSIQEVFPNFSKDIEMSCEIDPRHFTKEHMQTLFDRGFNRLSFGVQDFDFEV
CCCHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHH
QKAIHRIQPFEMVQESVKLARDYGIKSINFDLIYGLPNQTKESFLKTLEWVLKLNPDRLA
HHHHHHCCHHHHHHHHHHHHHHCCCCEECEEEEECCCCHHHHHHHHHHHHHHHCCCCCEE
VFNYAHVPWVKKTMRKIDETLLPSPRDKLEILESLISFLEKANYQMIGMDHFAKSDNELY
EEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEHHHHCCCCCCEE
LALQKAELRRNFQGYTTKKFTQTIGIGVTSIGEGSDYYTQNYKDLHHYEKALDLGHLPVE
EEEEHHHHHHCCCCCCHHHHHHHHCCCEEECCCCCCHHHCCHHHHHHHHHHHHCCCCCHH
RGVALSQEDVLRKEVIMQMMSNLKLDYSKIEEKFSVDFKAHFKKELEKLKPYEEAGLLVF
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCHHHCCEEEE
NPKGFEMTRTGGMLVRNMAMEFDAYLRGGEKHFSKTL
CCCCCEEECCCHHHHHHHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]