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The map label for this gene is rnhA [H]

Identifier: 108563071

GI number: 108563071

Start: 674125

End: 674556

Strand: Direct

Name: rnhA [H]

Synonym: HPAG1_0646

Alternate gene names: 108563071

Gene position: 674125-674556 (Clockwise)

Preceding gene: 108563070

Following gene: 108563072

Centisome position: 42.23

GC content: 40.28

Gene sequence:

>432_bases
ATGCAAGAAATTGAAATTTTTTGCGATGGCTCTTCTTTAGGCAATCCCGGGCCAGGCGGTTATGCGGCGATTTTACGCTA
TAAAGATAAAGAAAAAACCATCAGTGGAGGCGAAGAATTCACCACGAATAACCGCATGGAATTAAGAGCACTCAATGAAG
CGTTAAAAATTTTGAAACGCCCATGCCGTATCACGCTTTATAGCGATTCGCAATACGTGTGCCAAGCGATCAATGTGTGG
CTGGTTAACTGGCAAAAAAAGAATTTTTCTAAAGTTAAAAATGTGGATTTATGGAAAGAATTTTTAAAAGTCTCTAAAGG
GCATTTGATTATGGCTGTTTGGATCAAGGGGCATAACGGGCATGCTGAGAATGAACGATGCGATAGCCTTGCTAAATTAG
AGGCGCAAAAACGCACTAAAACGATCACTTAA

Upstream 100 bases:

>100_bases
ATCTTTCCTTTTGAAAGCCATAGGTGTCCTGTGTGTTACCAGTTAGCGTTTATGGATATGGTGCTTAAAATCTCTAAAGA
AAGCTATGGGAGTGGATTGA

Downstream 100 bases:

>100_bases
AGGGAAAAATGATGAAAAACAAACGCTCTCAAAACAGCCCTTATGTAACGCCTAATAACCCTTATACAACGCTAGAAAAA
GCTTTGGGGTATTCTTTTAA

Product: ribonuclease H

Products: NA

Alternate protein names: RNase H [H]

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MQEIEIFCDGSSLGNPGPGGYAAILRYKDKEKTISGGEEFTTNNRMELRALNEALKILKRPCRITLYSDSQYVCQAINVW
LVNWQKKNFSKVKNVDLWKEFLKVSKGHLIMAVWIKGHNGHAENERCDSLAKLEAQKRTKTIT

Sequences:

>Translated_143_residues
MQEIEIFCDGSSLGNPGPGGYAAILRYKDKEKTISGGEEFTTNNRMELRALNEALKILKRPCRITLYSDSQYVCQAINVW
LVNWQKKNFSKVKNVDLWKEFLKVSKGHLIMAVWIKGHNGHAENERCDSLAKLEAQKRTKTIT
>Mature_143_residues
MQEIEIFCDGSSLGNPGPGGYAAILRYKDKEKTISGGEEFTTNNRMELRALNEALKILKRPCRITLYSDSQYVCQAINVW
LVNWQKKNFSKVKNVDLWKEFLKVSKGHLIMAVWIKGHNGHAENERCDSLAKLEAQKRTKTIT

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0328

COG function: function code L; Ribonuclease HI

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase H domain [H]

Homologues:

Organism=Escherichia coli, GI1786408, Length=144, Percent_Identity=52.7777777777778, Blast_Score=152, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6323890, Length=166, Percent_Identity=30.1204819277108, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022892
- InterPro:   IPR012337
- InterPro:   IPR002156 [H]

Pfam domain/function: PF00075 RnaseH [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 16346; Mature: 16346

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50879 RNASE_H

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEIEIFCDGSSLGNPGPGGYAAILRYKDKEKTISGGEEFTTNNRMELRALNEALKILKR
CCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
PCRITLYSDSQYVCQAINVWLVNWQKKNFSKVKNVDLWKEFLKVSKGHLIMAVWIKGHNG
CCEEEEECCCHHHHHHHEEEEEEECCCCHHHHCCHHHHHHHHHHCCCCEEEEEEEECCCC
HAENERCDSLAKLEAQKRTKTIT
CCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQEIEIFCDGSSLGNPGPGGYAAILRYKDKEKTISGGEEFTTNNRMELRALNEALKILKR
CCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
PCRITLYSDSQYVCQAINVWLVNWQKKNFSKVKNVDLWKEFLKVSKGHLIMAVWIKGHNG
CCEEEEECCCHHHHHHHEEEEEEECCCCHHHHCCHHHHHHHHHHCCCCEEEEEEEECCCC
HAENERCDSLAKLEAQKRTKTIT
CCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA