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The map label for this gene is hydD [H]

Identifier: 108563042

GI number: 108563042

Start: 645388

End: 645924

Strand: Direct

Name: hydD [H]

Synonym: HPAG1_0617

Alternate gene names: 108563042

Gene position: 645388-645924 (Clockwise)

Preceding gene: 108563041

Following gene: 108563043

Centisome position: 40.43

GC content: 43.76

Gene sequence:

>537_bases
ATGAGTCAAAAAATCCTGATTCTTGGCATTGGCAATATCCTTTTTGGCGATGAAGGGATTGGGGTGCATCTAGCCCACTA
CCTCAAAAGGAATTTTTCTTTTTTCCCTAGCGTGGATATTGTGGATGGGGGGACTATGGCTCAGCAACTCATTCCTTTAA
TCACTTCGTATGAAAAGGTCTTGATTTTAGATTGCGTGAGCGCTAAAGGCGTTGAGATAGGCTCAGTCTATGCCTTTGAT
TTTAAGGACGCTCCTAAAGAAATCACATGGGCTGGGAGCGCGCATGAAGTGGAAATGCTGCACACTTTAAGGCTCACGGA
GTTTTTAGGGGATTTGCCTAAAACTTTTATCGTGGGGCTTGTGCCTTTTGTGATAGGGAGCGAGACCACTTTCAAGCTCT
CAAGCGAAATGTTAAACGCTTTAGAAACAGCCTTAAAAGCCATAGAAACTCGACTCAACGCATGGGGAGTTAAAATGCAA
CGCACCGATCATATCGCTTTAGAGTGTATCGCTGAACTCTCTTATAAGGGTTTTTGA

Upstream 100 bases:

>100_bases
TGTTTGTCCCTGTGCATGTTTATATGGTGTTTTTCCATTCTATCCGGTATGAAAGTTCGGGGGCGGATTCTATGATTAAT
GGTTATGGTTATACCAAAGA

Downstream 100 bases:

>100_bases
ATTGGCGTTTGTCTTTCTTTTTAAATGCGTTAATGAAAAAACAAGCCTGAATTTTATGCCCCTTTTAGAGCAAATAGCGT
TCCATTTGCAAGCGCGTTTT

Product: quinone-reactive Ni/Fe hydrogenase HydD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MSQKILILGIGNILFGDEGIGVHLAHYLKRNFSFFPSVDIVDGGTMAQQLIPLITSYEKVLILDCVSAKGVEIGSVYAFD
FKDAPKEITWAGSAHEVEMLHTLRLTEFLGDLPKTFIVGLVPFVIGSETTFKLSSEMLNALETALKAIETRLNAWGVKMQ
RTDHIALECIAELSYKGF

Sequences:

>Translated_178_residues
MSQKILILGIGNILFGDEGIGVHLAHYLKRNFSFFPSVDIVDGGTMAQQLIPLITSYEKVLILDCVSAKGVEIGSVYAFD
FKDAPKEITWAGSAHEVEMLHTLRLTEFLGDLPKTFIVGLVPFVIGSETTFKLSSEMLNALETALKAIETRLNAWGVKMQ
RTDHIALECIAELSYKGF
>Mature_177_residues
SQKILILGIGNILFGDEGIGVHLAHYLKRNFSFFPSVDIVDGGTMAQQLIPLITSYEKVLILDCVSAKGVEIGSVYAFDF
KDAPKEITWAGSAHEVEMLHTLRLTEFLGDLPKTFIVGLVPFVIGSETTFKLSSEMLNALETALKAIETRLNAWGVKMQR
TDHIALECIAELSYKGF

Specific function: Protease Involved In The C-Terminal Processing Of Hybc, The Large Subunit Of Hydrogenase 2. Specifically Cleaves Off A 15 Amino Acid Peptide From The C Terminus Of The Precursor Of Hybc. [C]

COG id: COG0680

COG function: function code C; Ni,Fe-hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A31 family [H]

Homologues:

Organism=Escherichia coli, GI1789367, Length=156, Percent_Identity=28.8461538461538, Blast_Score=70, Evalue=5e-14,
Organism=Escherichia coli, GI1787209, Length=180, Percent_Identity=29.4444444444444, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004419
- InterPro:   IPR000671 [H]

Pfam domain/function: PF01750 HycI [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 19638; Mature: 19507

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKILILGIGNILFGDEGIGVHLAHYLKRNFSFFPSVDIVDGGTMAQQLIPLITSYEKV
CCCCEEEEEECCEEECCCCCHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHCCCCE
LILDCVSAKGVEIGSVYAFDFKDAPKEITWAGSAHEVEMLHTLRLTEFLGDLPKTFIVGL
EEEEECCCCCCEECEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
VPFVIGSETTFKLSSEMLNALETALKAIETRLNAWGVKMQRTDHIALECIAELSYKGF
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SQKILILGIGNILFGDEGIGVHLAHYLKRNFSFFPSVDIVDGGTMAQQLIPLITSYEKV
CCCEEEEEECCEEECCCCCHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHCCCCE
LILDCVSAKGVEIGSVYAFDFKDAPKEITWAGSAHEVEMLHTLRLTEFLGDLPKTFIVGL
EEEEECCCCCCEECEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
VPFVIGSETTFKLSSEMLNALETALKAIETRLNAWGVKMQRTDHIALECIAELSYKGF
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1587288; 9639603; 14500908 [H]