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The map label for this gene is clpB [H]

Identifier: 108562691

GI number: 108562691

Start: 270128

End: 272698

Strand: Direct

Name: clpB [H]

Synonym: HPAG1_0266

Alternate gene names: 108562691

Gene position: 270128-272698 (Clockwise)

Preceding gene: 108562690

Following gene: 108562692

Centisome position: 16.92

GC content: 40.88

Gene sequence:

>2571_bases
ATGAATTTATTTGAAAAAATGACTGACCAATTGCATGAGGCTTTAGACAGTGCGCTCGCTTTAGCTTTACACCATAAAAA
CGCTGAAGTAACGCCCTTGCACATGCTTTTTGCCATGCTTAATAACTCCCAAGGCATTCTCATTCAAGCCTTACAAAAAA
TGCCTGTGGATATTGAAGCTTTAAAGCTTAGCGTTCAAAGCGAGTTGAATAAGTTCGCTAAAGTTTCACAAATCAGCAAG
CAAAATATCCAATTAAACCAAGCTTTAATCCAAAGTTTAGAAAACGCTCAAGGCTTGATGGCTAAAAGGGGCGATTCTTT
CATCGCTACCGATGTGTATCTTTTGGCGAATATGGGTCTTTTTGAAAGCGTTTTAAAGCCTTATTTAGACACTAAGGAAT
TGCAAAAAACTTTAGAATCTTTGAGAAAAGGCGCGACTATTCAAGGTAAAAACGATGATTCTAATTTGGAAAGTTTAGAA
AAATTTGGCATTGATTTGACGCAAAAAGCCTTAGACAATAAGCTCGATCCGGTGATCGGAAGAGATGAAGAAATCATTCG
CATGATGCAAATTTTGATCAGAAAAACAAAAAATAACCCTATTTTATTGGGTGAGCCTGGAGTGGGGAAAACGGCGGTTG
TGGAAGGGTTAGCCCAACGCATTGTGAATAAAGAAGTGCCTAAAACGCTTTTAAACAAACGAGTTATCGCTTTAGACTTA
AGCTTATTGGTGGCTGGGGCGAAATACAGAGGCGAGTTTGAAGAGCGCCTGAAAAAGGTGATTGAAGAAGTTAAAAAAAG
CGCGAATGTGATTTTATTCATTGATGAAATCCACACGATTGTGGGGGCTGGGGCTAGTGAGGGGGGCATGGATGCGGCGA
ATATTTTAAAACCCGCGCTCGCTAGGGGGGAATTGCACACGATTGGAGCGACCACTTTAAAAGAATACCGCAAGTATTTT
GAAAAAGACATGGCATTGCAAAGGCGTTTCCAACCCATTTTACTCAATGAGCCTAGCATCAATGAAGCTTTACAGATTTT
AAGGGGGTTGAAAGAAACTTTAGAAACGCACCATAATATCACCATCAATGACTCCGCGCTCATAGCGAGCGCTAAACTCT
CTAGCCGTTATATCACCGATAGGTTTTTACCCGATAAAGCGATTGATTTGATTGATGAGGGAGCGGCTCAATTAAAAATG
CAAATGGAATCAGAGCCGGCCAAACTCTCTAGCGTGAAGCGCTCCATTCAAAGACTAGAAATGGAAAAACAAGCCCTTGA
AATGGAAAAAAAAGAGAGCAATGCCAAACGCATGCAAGAAATCCTTAAAGAATTGAGCGATTTGAAAGAAGAAAAAATCC
AATTAGAAGCGCAATTTGAAAACGAAAAAGAAGTGTTCAAAGAAATTTCACGCTTGAAAATGGAAATGGAAAGCTTGAAA
AAAGAGGCTGAGAGGTTTAAACGCAATGGGGATTACCAGCAAGCGGGTGAAATTGAATACTCTAAAATCCCTGAAAATAA
AAAGAAAGAAGAAGAATTGCAGCACAAATGGGAAGCGATGCAACAAAATGGGGCGTTATTACAAAACGCTTTAACCGAAA
ACAATATCGCTGAGATCGTGAGCCAATGGACGCATATCCCAGTCCAAAAAATGCTCCAAAGCGAAAAAAATAGGGTTTTA
AACATTGAAAGCGAATTGCAAAAAAGAGTGGTGGGGCAAGAAAAAGCGATCAAAGCGATCGCTAAAGCGATTAAAAGGAA
TAAGGCCGGGCTTAGCGATAGCAACAAGCCCATAGGGAGTTTCCTCTTTTTAGGGCCAACAGGCGTGGGTAAAACCGAGA
GCGCTAAAGCCTTGGCGCAATTCTTGTTTGATAGCGATAAAAATCTTATACGAATTGACATGAGCGAATATTTGGAAAAG
CACTCTATAAGCCGTCTTATTGGGGCCGCTCCTGGGTATGTGGGCTATGAAGAAGGCGGGCAATTGACCGAAGCGGTGCG
CAGAAAGCCTTATAGCGTGGTGTTGTTAGATGAAGTGGAAAAAGCCCATCCGGATGTGTTTAACCTCTTGTTGCAGGTTT
TAGATGAAGGGCATTTAACCGATAGTAAGGGCGTGAGGGTGGATTTCAAAAACACGATTTTGATTTTAACCAGCAATGTG
GCTAGCGGCGTGCTTTTAGAAGAAAATTTGAGCGAAGCTGATAAGCAAAAAGCGATTAAAGAGAGCTTGAGGCAATTTTT
CAAGCCGGAATTTTTAAACCGCCTAGATGAAATCATCTCCTTTAACGCCCTAGATAGTCATGCTATCATTAATATCGTGG
GGATTCTCTTTGAAAACATTCAAAAAAAAGCGCTTGAAAGGGGCATTAATATAACCCTAGACGAAGAGGCAAAAGAATTG
ATCGCTGAAGCGGGATTTGACAGATTCTATGGCGCTAGACCCTTAAAGCGTGCGCTCTATGAAATGGTAGAAGACAAGCT
CGCTGAACTCATTTTAGAGGATAAAGTTAAAGAGAATGACAGCGTGGCGTTTGTGGTAGAAAATAACGAAATTGTGCCTA
AGATTAAGTGA

Upstream 100 bases:

>100_bases
TATTTTGGAGAGTTTGTCGTTAGTGTGAGCGTTTTAAAAACCTTTGAGGGTTAAAATAGTGTAAAATAGTAAAGATTTTA
CAACTCAAAAAGGATTGATA

Downstream 100 bases:

>100_bases
AGTTTGGTTATCCTAAAAAATATTAAGAAATGGTTATTTTTAAAAAAGGATTGAATGATGTTTGATAACACGCTTGTTAA
TCTCTTTGACACAGCGCCTC

Product: ATP-dependent protease binding subunit/heat shock protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 856; Mature: 856

Protein sequence:

>856_residues
MNLFEKMTDQLHEALDSALALALHHKNAEVTPLHMLFAMLNNSQGILIQALQKMPVDIEALKLSVQSELNKFAKVSQISK
QNIQLNQALIQSLENAQGLMAKRGDSFIATDVYLLANMGLFESVLKPYLDTKELQKTLESLRKGATIQGKNDDSNLESLE
KFGIDLTQKALDNKLDPVIGRDEEIIRMMQILIRKTKNNPILLGEPGVGKTAVVEGLAQRIVNKEVPKTLLNKRVIALDL
SLLVAGAKYRGEFEERLKKVIEEVKKSANVILFIDEIHTIVGAGASEGGMDAANILKPALARGELHTIGATTLKEYRKYF
EKDMALQRRFQPILLNEPSINEALQILRGLKETLETHHNITINDSALIASAKLSSRYITDRFLPDKAIDLIDEGAAQLKM
QMESEPAKLSSVKRSIQRLEMEKQALEMEKKESNAKRMQEILKELSDLKEEKIQLEAQFENEKEVFKEISRLKMEMESLK
KEAERFKRNGDYQQAGEIEYSKIPENKKKEEELQHKWEAMQQNGALLQNALTENNIAEIVSQWTHIPVQKMLQSEKNRVL
NIESELQKRVVGQEKAIKAIAKAIKRNKAGLSDSNKPIGSFLFLGPTGVGKTESAKALAQFLFDSDKNLIRIDMSEYLEK
HSISRLIGAAPGYVGYEEGGQLTEAVRRKPYSVVLLDEVEKAHPDVFNLLLQVLDEGHLTDSKGVRVDFKNTILILTSNV
ASGVLLEENLSEADKQKAIKESLRQFFKPEFLNRLDEIISFNALDSHAIINIVGILFENIQKKALERGINITLDEEAKEL
IAEAGFDRFYGARPLKRALYEMVEDKLAELILEDKVKENDSVAFVVENNEIVPKIK

Sequences:

>Translated_856_residues
MNLFEKMTDQLHEALDSALALALHHKNAEVTPLHMLFAMLNNSQGILIQALQKMPVDIEALKLSVQSELNKFAKVSQISK
QNIQLNQALIQSLENAQGLMAKRGDSFIATDVYLLANMGLFESVLKPYLDTKELQKTLESLRKGATIQGKNDDSNLESLE
KFGIDLTQKALDNKLDPVIGRDEEIIRMMQILIRKTKNNPILLGEPGVGKTAVVEGLAQRIVNKEVPKTLLNKRVIALDL
SLLVAGAKYRGEFEERLKKVIEEVKKSANVILFIDEIHTIVGAGASEGGMDAANILKPALARGELHTIGATTLKEYRKYF
EKDMALQRRFQPILLNEPSINEALQILRGLKETLETHHNITINDSALIASAKLSSRYITDRFLPDKAIDLIDEGAAQLKM
QMESEPAKLSSVKRSIQRLEMEKQALEMEKKESNAKRMQEILKELSDLKEEKIQLEAQFENEKEVFKEISRLKMEMESLK
KEAERFKRNGDYQQAGEIEYSKIPENKKKEEELQHKWEAMQQNGALLQNALTENNIAEIVSQWTHIPVQKMLQSEKNRVL
NIESELQKRVVGQEKAIKAIAKAIKRNKAGLSDSNKPIGSFLFLGPTGVGKTESAKALAQFLFDSDKNLIRIDMSEYLEK
HSISRLIGAAPGYVGYEEGGQLTEAVRRKPYSVVLLDEVEKAHPDVFNLLLQVLDEGHLTDSKGVRVDFKNTILILTSNV
ASGVLLEENLSEADKQKAIKESLRQFFKPEFLNRLDEIISFNALDSHAIINIVGILFENIQKKALERGINITLDEEAKEL
IAEAGFDRFYGARPLKRALYEMVEDKLAELILEDKVKENDSVAFVVENNEIVPKIK
>Mature_856_residues
MNLFEKMTDQLHEALDSALALALHHKNAEVTPLHMLFAMLNNSQGILIQALQKMPVDIEALKLSVQSELNKFAKVSQISK
QNIQLNQALIQSLENAQGLMAKRGDSFIATDVYLLANMGLFESVLKPYLDTKELQKTLESLRKGATIQGKNDDSNLESLE
KFGIDLTQKALDNKLDPVIGRDEEIIRMMQILIRKTKNNPILLGEPGVGKTAVVEGLAQRIVNKEVPKTLLNKRVIALDL
SLLVAGAKYRGEFEERLKKVIEEVKKSANVILFIDEIHTIVGAGASEGGMDAANILKPALARGELHTIGATTLKEYRKYF
EKDMALQRRFQPILLNEPSINEALQILRGLKETLETHHNITINDSALIASAKLSSRYITDRFLPDKAIDLIDEGAAQLKM
QMESEPAKLSSVKRSIQRLEMEKQALEMEKKESNAKRMQEILKELSDLKEEKIQLEAQFENEKEVFKEISRLKMEMESLK
KEAERFKRNGDYQQAGEIEYSKIPENKKKEEELQHKWEAMQQNGALLQNALTENNIAEIVSQWTHIPVQKMLQSEKNRVL
NIESELQKRVVGQEKAIKAIAKAIKRNKAGLSDSNKPIGSFLFLGPTGVGKTESAKALAQFLFDSDKNLIRIDMSEYLEK
HSISRLIGAAPGYVGYEEGGQLTEAVRRKPYSVVLLDEVEKAHPDVFNLLLQVLDEGHLTDSKGVRVDFKNTILILTSNV
ASGVLLEENLSEADKQKAIKESLRQFFKPEFLNRLDEIISFNALDSHAIINIVGILFENIQKKALERGINITLDEEAKEL
IAEAGFDRFYGARPLKRALYEMVEDKLAELILEDKVKENDSVAFVVENNEIVPKIK

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=322, Percent_Identity=37.2670807453416, Blast_Score=204, Evalue=4e-52,
Organism=Escherichia coli, GI1788943, Length=858, Percent_Identity=48.6013986013986, Blast_Score=827, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=424, Percent_Identity=37.7358490566038, Blast_Score=269, Evalue=6e-73,
Organism=Saccharomyces cerevisiae, GI6320464, Length=703, Percent_Identity=49.7866287339972, Blast_Score=699, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=865, Percent_Identity=39.0751445086705, Blast_Score=579, Evalue=1e-166,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 96458; Mature: 96458

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLFEKMTDQLHEALDSALALALHHKNAEVTPLHMLFAMLNNSQGILIQALQKMPVDIEA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCHHH
LKLSVQSELNKFAKVSQISKQNIQLNQALIQSLENAQGLMAKRGDSFIATDVYLLANMGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHH
FESVLKPYLDTKELQKTLESLRKGATIQGKNDDSNLESLEKFGIDLTQKALDNKLDPVIG
HHHHHHHCCCHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHCCHHHHHHHCCCCCCCCC
RDEEIIRMMQILIRKTKNNPILLGEPGVGKTAVVEGLAQRIVNKEVPKTLLNKRVIALDL
CCHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SLLVAGAKYRGEFEERLKKVIEEVKKSANVILFIDEIHTIVGAGASEGGMDAANILKPAL
HHHHHCHHHCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHH
ARGELHTIGATTLKEYRKYFEKDMALQRRFQPILLNEPSINEALQILRGLKETLETHHNI
HCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCE
TINDSALIASAKLSSRYITDRFLPDKAIDLIDEGAAQLKMQMESEPAKLSSVKRSIQRLE
EECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHH
MEKQALEMEKKESNAKRMQEILKELSDLKEEKIQLEAQFENEKEVFKEISRLKMEMESLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KEAERFKRNGDYQQAGEIEYSKIPENKKKEEELQHKWEAMQQNGALLQNALTENNIAEIV
HHHHHHHHCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHH
SQWTHIPVQKMLQSEKNRVLNIESELQKRVVGQEKAIKAIAKAIKRNKAGLSDSNKPIGS
HHHHCCCHHHHHHHHCCCEECHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
FLFLGPTGVGKTESAKALAQFLFDSDKNLIRIDMSEYLEKHSISRLIGAAPGYVGYEEGG
EEEECCCCCCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCC
QLTEAVRRKPYSVVLLDEVEKAHPDVFNLLLQVLDEGHLTDSKGVRVDFKNTILILTSNV
HHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEECCC
ASGVLLEENLSEADKQKAIKESLRQFFKPEFLNRLDEIISFNALDSHAIINIVGILFENI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
QKKALERGINITLDEEAKELIAEAGFDRFYGARPLKRALYEMVEDKLAELILEDKVKEND
HHHHHHCCCCEEECHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
SVAFVVENNEIVPKIK
CEEEEEECCCCCCCCC
>Mature Secondary Structure
MNLFEKMTDQLHEALDSALALALHHKNAEVTPLHMLFAMLNNSQGILIQALQKMPVDIEA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCHHH
LKLSVQSELNKFAKVSQISKQNIQLNQALIQSLENAQGLMAKRGDSFIATDVYLLANMGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHH
FESVLKPYLDTKELQKTLESLRKGATIQGKNDDSNLESLEKFGIDLTQKALDNKLDPVIG
HHHHHHHCCCHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHCCHHHHHHHCCCCCCCCC
RDEEIIRMMQILIRKTKNNPILLGEPGVGKTAVVEGLAQRIVNKEVPKTLLNKRVIALDL
CCHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SLLVAGAKYRGEFEERLKKVIEEVKKSANVILFIDEIHTIVGAGASEGGMDAANILKPAL
HHHHHCHHHCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHH
ARGELHTIGATTLKEYRKYFEKDMALQRRFQPILLNEPSINEALQILRGLKETLETHHNI
HCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCE
TINDSALIASAKLSSRYITDRFLPDKAIDLIDEGAAQLKMQMESEPAKLSSVKRSIQRLE
EECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHH
MEKQALEMEKKESNAKRMQEILKELSDLKEEKIQLEAQFENEKEVFKEISRLKMEMESLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KEAERFKRNGDYQQAGEIEYSKIPENKKKEEELQHKWEAMQQNGALLQNALTENNIAEIV
HHHHHHHHCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHH
SQWTHIPVQKMLQSEKNRVLNIESELQKRVVGQEKAIKAIAKAIKRNKAGLSDSNKPIGS
HHHHCCCHHHHHHHHCCCEECHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
FLFLGPTGVGKTESAKALAQFLFDSDKNLIRIDMSEYLEKHSISRLIGAAPGYVGYEEGG
EEEECCCCCCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCC
QLTEAVRRKPYSVVLLDEVEKAHPDVFNLLLQVLDEGHLTDSKGVRVDFKNTILILTSNV
HHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEECCC
ASGVLLEENLSEADKQKAIKESLRQFFKPEFLNRLDEIISFNALDSHAIINIVGILFENI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
QKKALERGINITLDEEAKELIAEAGFDRFYGARPLKRALYEMVEDKLAELILEDKVKEND
HHHHHHCCCCEEECHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
SVAFVVENNEIVPKIK
CEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]