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The map label for this gene is radA [H]

Identifier: 108562650

GI number: 108562650

Start: 228392

End: 229762

Strand: Direct

Name: radA [H]

Synonym: HPAG1_0225

Alternate gene names: 108562650

Gene position: 228392-229762 (Clockwise)

Preceding gene: 108562649

Following gene: 108562651

Centisome position: 14.31

GC content: 41.72

Gene sequence:

>1371_bases
GTGATTTTAAAAAAGAGTGGTATTTTGGCTAAAAAAACTTCTTTATTTGAGTGTCAGCATTGCGGTTTTACAAGCCCTAA
GTGGCTAGGCAAGTGCGTTCAATGCAACGCATGGGAGAGTTTTATAGAATTGAACCAAGCTCAAAAGGAAGTTTTAAACA
CGCTTAAAAATCCGATCCCAAAAGCGCAAAAAAGCGTTTCTATCGCTGCAATTGAGCATGAAGAAGTGATTAAGTTTTCT
TCCACTCAAAGCGAATTAGATATTGTTTTAGGTGGGGGGATCGCTAAAGGGGGGTTGTATTTAGTGGGGGGGAGTCCTGG
GGTGGGGAAATCCACTCTGCTTTTAAAAGTGGCTTCTGGCTTAGCCAAAAACCAGCAAAAGGTTTTGTATGTGAGCGGGG
AAGAGAGCTTGAGCCAGATTAAAATGCGCGCCACTAGGTTGGATTGCATAGAAAAAGAATTGTATTTGCTCAATGAAATC
AATTGGCCTGTGATTAAGGCTAATATAGAAAGCGAAAATTATTTTGCGTGCGTGATTGATTCCATTCAAACGCTTTATTC
GCCAGAGATTTCTTCAGCGCCCGGCTCTATTTCGCAAGTGCGAGAGATCACTTTTGAGCTCATGCGTTTGGCTAAAACAA
GAAATATTGCTATTTTTATCATCGGTCATATCACTAAAGAAGGGAGTATTGCAGGGCCTAGAGTGCTAGAGCATATGGTG
GATAGCGTGCTGTATTTTGAAGGCGATCCCAGTAGGGAATTAAGGATTTTAAGGAGTTTTAAAAACCGCTTTGGCCCTAC
GAGTGAAATCGGCTTGTTTGAGATGAAAGAGCAGGGTTTGGTGAGCGCTAAAGAAGCTTCAAGTTTGTTTTTTTCAAAAG
AAGAGCCTATGGAGGGGAGTGCCATTACCATCACTTTAGAAGGCTCAAGAGCGTTGATTTTAGAGATTCAGGCGTTGGTG
AGCGAATGCAGTTTCGGATCGCCCAAACGATTAGCGAACGGGTTTGACACCAACCGCCTTAACATGCTCATCGCTTTGTT
AGAAAAAAAGCTAGAAATCCCTTTAAACCGCCATGATGTGTTCATTAATGTGAGCGGGGGCATTAAGATTAGCGAGCCGG
CTTGCGATTTAGCGGTCATTGCCAGTATCCTTTCAAGCTTTAAAAACAGAAAGATTGACAATAAAACGGCGTTTTTGGGC
GAAGTGAGTTTGAATGGTAGGATTTTAGAAGCCCCTAATTTGAACGCTAGATTGAAAGAAATGGAAAATTATGGCTTTTT
AAAAGCCATTTTGCCTAAAAAACCCAGTCAAAAAACCTCTATCAAATGCTATGAAGCCAATGCGGTGGGGAAGATTGTTG
AATGGATGTGA

Upstream 100 bases:

>100_bases
CGCTTGATAACTTTTTAACTTGTTTTGAGTGTAGCTTTACGAGTTTTGCTTTTGCTATAGAACAAAACCAAAACCCCATT
TTTATCTGGTCTTTAGCTGT

Downstream 100 bases:

>100_bases
TTTTAATTTTTGTTACCTAATAGAACAGAGTCTTATTAAAATTTAAACTCAATTTAAAGAACAACTACCATTTTTTTTAG
TTATAATGGCAAACACCATT

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MILKKSGILAKKTSLFECQHCGFTSPKWLGKCVQCNAWESFIELNQAQKEVLNTLKNPIPKAQKSVSIAAIEHEEVIKFS
STQSELDIVLGGGIAKGGLYLVGGSPGVGKSTLLLKVASGLAKNQQKVLYVSGEESLSQIKMRATRLDCIEKELYLLNEI
NWPVIKANIESENYFACVIDSIQTLYSPEISSAPGSISQVREITFELMRLAKTRNIAIFIIGHITKEGSIAGPRVLEHMV
DSVLYFEGDPSRELRILRSFKNRFGPTSEIGLFEMKEQGLVSAKEASSLFFSKEEPMEGSAITITLEGSRALILEIQALV
SECSFGSPKRLANGFDTNRLNMLIALLEKKLEIPLNRHDVFINVSGGIKISEPACDLAVIASILSSFKNRKIDNKTAFLG
EVSLNGRILEAPNLNARLKEMENYGFLKAILPKKPSQKTSIKCYEANAVGKIVEWM

Sequences:

>Translated_456_residues
MILKKSGILAKKTSLFECQHCGFTSPKWLGKCVQCNAWESFIELNQAQKEVLNTLKNPIPKAQKSVSIAAIEHEEVIKFS
STQSELDIVLGGGIAKGGLYLVGGSPGVGKSTLLLKVASGLAKNQQKVLYVSGEESLSQIKMRATRLDCIEKELYLLNEI
NWPVIKANIESENYFACVIDSIQTLYSPEISSAPGSISQVREITFELMRLAKTRNIAIFIIGHITKEGSIAGPRVLEHMV
DSVLYFEGDPSRELRILRSFKNRFGPTSEIGLFEMKEQGLVSAKEASSLFFSKEEPMEGSAITITLEGSRALILEIQALV
SECSFGSPKRLANGFDTNRLNMLIALLEKKLEIPLNRHDVFINVSGGIKISEPACDLAVIASILSSFKNRKIDNKTAFLG
EVSLNGRILEAPNLNARLKEMENYGFLKAILPKKPSQKTSIKCYEANAVGKIVEWM
>Mature_456_residues
MILKKSGILAKKTSLFECQHCGFTSPKWLGKCVQCNAWESFIELNQAQKEVLNTLKNPIPKAQKSVSIAAIEHEEVIKFS
STQSELDIVLGGGIAKGGLYLVGGSPGVGKSTLLLKVASGLAKNQQKVLYVSGEESLSQIKMRATRLDCIEKELYLLNEI
NWPVIKANIESENYFACVIDSIQTLYSPEISSAPGSISQVREITFELMRLAKTRNIAIFIIGHITKEGSIAGPRVLEHMV
DSVLYFEGDPSRELRILRSFKNRFGPTSEIGLFEMKEQGLVSAKEASSLFFSKEEPMEGSAITITLEGSRALILEIQALV
SECSFGSPKRLANGFDTNRLNMLIALLEKKLEIPLNRHDVFINVSGGIKISEPACDLAVIASILSSFKNRKIDNKTAFLG
EVSLNGRILEAPNLNARLKEMENYGFLKAILPKKPSQKTSIKCYEANAVGKIVEWM

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=426, Percent_Identity=41.5492957746479, Blast_Score=340, Evalue=8e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 50278; Mature: 50278

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILKKSGILAKKTSLFECQHCGFTSPKWLGKCVQCNAWESFIELNQAQKEVLNTLKNPIP
CEEECCCCEEECCCHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
KAQKSVSIAAIEHEEVIKFSSTQSELDIVLGGGIAKGGLYLVGGSPGVGKSTLLLKVASG
CHHHCEEEEEECHHHHHEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHH
LAKNQQKVLYVSGEESLSQIKMRATRLDCIEKELYLLNEINWPVIKANIESENYFACVID
HCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEHH
SIQTLYSPEISSAPGSISQVREITFELMRLAKTRNIAIFIIGHITKEGSIAGPRVLEHMV
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHHH
DSVLYFEGDPSRELRILRSFKNRFGPTSEIGLFEMKEQGLVSAKEASSLFFSKEEPMEGS
HHEEEECCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHEECCCCCCCCC
AITITLEGSRALILEIQALVSECSFGSPKRLANGFDTNRLNMLIALLEKKLEIPLNRHDV
EEEEEECCCCEEEHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEE
FINVSGGIKISEPACDLAVIASILSSFKNRKIDNKTAFLGEVSLNGRILEAPNLNARLKE
EEEECCCEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEECCCCCHHHHH
MENYGFLKAILPKKPSQKTSIKCYEANAVGKIVEWM
HHCCCCEEEECCCCCCCCCEEEEEECCCHHHHHHCC
>Mature Secondary Structure
MILKKSGILAKKTSLFECQHCGFTSPKWLGKCVQCNAWESFIELNQAQKEVLNTLKNPIP
CEEECCCCEEECCCHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
KAQKSVSIAAIEHEEVIKFSSTQSELDIVLGGGIAKGGLYLVGGSPGVGKSTLLLKVASG
CHHHCEEEEEECHHHHHEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHH
LAKNQQKVLYVSGEESLSQIKMRATRLDCIEKELYLLNEINWPVIKANIESENYFACVID
HCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEHH
SIQTLYSPEISSAPGSISQVREITFELMRLAKTRNIAIFIIGHITKEGSIAGPRVLEHMV
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHHH
DSVLYFEGDPSRELRILRSFKNRFGPTSEIGLFEMKEQGLVSAKEASSLFFSKEEPMEGS
HHEEEECCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHEECCCCCCCCC
AITITLEGSRALILEIQALVSECSFGSPKRLANGFDTNRLNMLIALLEKKLEIPLNRHDV
EEEEEECCCCEEEHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEE
FINVSGGIKISEPACDLAVIASILSSFKNRKIDNKTAFLGEVSLNGRILEAPNLNARLKE
EEEECCCEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEECCCCCHHHHH
MENYGFLKAILPKKPSQKTSIKCYEANAVGKIVEWM
HHCCCCEEEECCCCCCCCCEEEEEECCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]