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The map label for this gene is tpiA [H]

Identifier: 108562613

GI number: 108562613

Start: 195209

End: 195913

Strand: Direct

Name: tpiA [H]

Synonym: HPAG1_0188

Alternate gene names: 108562613

Gene position: 195209-195913 (Clockwise)

Preceding gene: 108562608

Following gene: 108562614

Centisome position: 12.23

GC content: 34.61

Gene sequence:

>705_bases
ATGACAAAAATTGCCATGGCTAATTTTAAATCCGCTATGCCTATTTTTAAAAGCCATGCGTATTTAAAAGAATTAGAAAA
GACTTTAAAACCGCAGCATTTTGACAGGGTGTTTGTATTCCCTGATTTTTTGGGGTTATTGCCTAATGCGTTTTTGCATT
TCACTTTAGGGGCGCAAAACGCTTACCCTAGAGATTGTGGGGCTTTTACCGGTGAAATCACTTCAAAGCATTTAGAAGAA
CTCAAAATCCACACGCTTTTAATAGGGCATAGCGAGAGGCGAACGCTTTTAAAAGAAAGCCCTAGCTTTTTGAAAGAAAA
GTTTGATTTTTTTAAAGATAAAAATTTTAAAATTGTCTATTGTATTGGCGAAGAATTGATAACCAGAGAAAAGGGTTTTA
AGGCTGTAAAGGAATTTTTAAGCGAGCAATTAGAAAATATTGATCTTAATTATTCCAATTTAATTGTGGCGTATGAGCCT
ATTTGGGCGATTGGCACCAAAAAAAGTGCTTCTTTAGAAGATATTTACCTCACGCATGGTTTTTTAAAACAAATCTTAAA
TCAAAAAACGCCCTTGTTGTATGGGGGGAGCGTGAACATACAAAACGCTAAAGAAATTTTAGGGATTGATAGCGTGGATG
GCTTATTGATTGGGAGCGCGTCTTGGGAATTAGAAAATTTTAAAACAATCATTTCATTTTTATAA

Upstream 100 bases:

>100_bases
AAAATTCAATTCAAGGGGGTTATTGTTTAAAATTTACATTTTTTAAACGCTATTAGATATAATAAGGGATAGTTACCACC
TATAAAATAAGGATCGTTCA

Downstream 100 bases:

>100_bases
AGGAAAATCATGGGATTTTTAAAAGGTAAAAAAGGGCTTATTGTAGGGGTGGCGAATAATAAATCCATCGCTTATGGGAT
CGCTCAATCTTGTTTCAATC

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MTKIAMANFKSAMPIFKSHAYLKELEKTLKPQHFDRVFVFPDFLGLLPNAFLHFTLGAQNAYPRDCGAFTGEITSKHLEE
LKIHTLLIGHSERRTLLKESPSFLKEKFDFFKDKNFKIVYCIGEELITREKGFKAVKEFLSEQLENIDLNYSNLIVAYEP
IWAIGTKKSASLEDIYLTHGFLKQILNQKTPLLYGGSVNIQNAKEILGIDSVDGLLIGSASWELENFKTIISFL

Sequences:

>Translated_234_residues
MTKIAMANFKSAMPIFKSHAYLKELEKTLKPQHFDRVFVFPDFLGLLPNAFLHFTLGAQNAYPRDCGAFTGEITSKHLEE
LKIHTLLIGHSERRTLLKESPSFLKEKFDFFKDKNFKIVYCIGEELITREKGFKAVKEFLSEQLENIDLNYSNLIVAYEP
IWAIGTKKSASLEDIYLTHGFLKQILNQKTPLLYGGSVNIQNAKEILGIDSVDGLLIGSASWELENFKTIISFL
>Mature_233_residues
TKIAMANFKSAMPIFKSHAYLKELEKTLKPQHFDRVFVFPDFLGLLPNAFLHFTLGAQNAYPRDCGAFTGEITSKHLEEL
KIHTLLIGHSERRTLLKESPSFLKEKFDFFKDKNFKIVYCIGEELITREKGFKAVKEFLSEQLENIDLNYSNLIVAYEPI
WAIGTKKSASLEDIYLTHGFLKQILNQKTPLLYGGSVNIQNAKEILGIDSVDGLLIGSASWELENFKTIISFL

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=194, Percent_Identity=34.5360824742268, Blast_Score=110, Evalue=9e-25,
Organism=Homo sapiens, GI226529917, Length=194, Percent_Identity=34.5360824742268, Blast_Score=110, Evalue=1e-24,
Organism=Escherichia coli, GI1790353, Length=191, Percent_Identity=35.0785340314136, Blast_Score=122, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17536593, Length=177, Percent_Identity=38.4180790960452, Blast_Score=123, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6320255, Length=183, Percent_Identity=36.0655737704918, Blast_Score=115, Evalue=4e-27,
Organism=Drosophila melanogaster, GI28572008, Length=218, Percent_Identity=34.8623853211009, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28572006, Length=218, Percent_Identity=34.8623853211009, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28572004, Length=192, Percent_Identity=36.9791666666667, Blast_Score=121, Evalue=5e-28,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 26686; Mature: 26555

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIAMANFKSAMPIFKSHAYLKELEKTLKPQHFDRVFVFPDFLGLLPNAFLHFTLGAQN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHEEEEECCCC
AYPRDCGAFTGEITSKHLEELKIHTLLIGHSERRTLLKESPSFLKEKFDFFKDKNFKIVY
CCCCCCCCCCHHHHHHHHHHHHHHHEEECCCHHHHHHHCCHHHHHHHHHHHCCCCCEEEE
CIGEELITREKGFKAVKEFLSEQLENIDLNYSNLIVAYEPIWAIGTKKSASLEDIYLTHG
EECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEECCCCCCCHHHHHHHHH
FLKQILNQKTPLLYGGSVNIQNAKEILGIDSVDGLLIGSASWELENFKTIISFL
HHHHHHCCCCCEEECCCCCCCCHHHHHCCCCCCCEEEECCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TKIAMANFKSAMPIFKSHAYLKELEKTLKPQHFDRVFVFPDFLGLLPNAFLHFTLGAQN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHEEEEECCCC
AYPRDCGAFTGEITSKHLEELKIHTLLIGHSERRTLLKESPSFLKEKFDFFKDKNFKIVY
CCCCCCCCCCHHHHHHHHHHHHHHHEEECCCHHHHHHHCCHHHHHHHHHHHCCCCCEEEE
CIGEELITREKGFKAVKEFLSEQLENIDLNYSNLIVAYEPIWAIGTKKSASLEDIYLTHG
EECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEECCCCCCCHHHHHHHHH
FLKQILNQKTPLLYGGSVNIQNAKEILGIDSVDGLLIGSASWELENFKTIISFL
HHHHHHCCCCCEEECCCCCCCCHHHHHCCCCCCCEEEECCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA