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The map label for this gene is lutA [H]

Identifier: 108562562

GI number: 108562562

Start: 145051

End: 145779

Strand: Reverse

Name: lutA [H]

Synonym: HPAG1_0137

Alternate gene names: 108562562

Gene position: 145779-145051 (Counterclockwise)

Preceding gene: 108562565

Following gene: 108562561

Centisome position: 9.13

GC content: 40.19

Gene sequence:

>729_bases
TTGAAAGTCAATTTCTTTGCTACTTGTCTAGGAGCAGCCATTTATAGCAACGCATCGCTTAACGCTATCAAATTACTCCG
TAAGGAAAATTTGGAAGTGGTTTTCAAAAAAGACCAGACATGTTGCGGCCAGCCAAGCTATAACTCAGGATACTATGAAG
AGACAAAAAAAGTCGTTTTATACAATATCAAACTTTATTCCAATAACGACTACCCTATTATTTTGCCCAGCGGTTCATGC
ACAGGGATGATGCGGCATGATTATTTGGAATTGTTTGAAGGGCATGCGGAATTTAACATGGTTAAAGATTTTTGCTCTAG
GGTGTATGAATTGAGCGAGTTTTTGGATAAAAAATTGCAAGTCAAATACGAAGATAAGGGCGAACCCCTTAAAATCACAT
GGCATTCTAATTGCCATGCCTTAAGGGTGGCTAAAGTGATTGACTCGGCGAAAAACCTCATCAGACAGCTCAAAAATGTG
GAACTCATTGAATTGGAAAAAGAAGAAGAATGCTGCGGGTTTGGGGGGACATTTTCGGTCAAAGAGCCTGAAATTTCAGC
GGTTATGGTCAAAGAAAAGATTAAAGACATAGAAAGCCGTCAGGTGGATGTGATTGTTTCAGCGGATGCTGGGTGTTTGA
TGAATATCAGCACCGCTATGCAAAAAATGGGCTCTCTAACAAAGCCCATGCATTTTTACGACTTTTTAGCCTCAAGGCTT
GGGCTTTAA

Upstream 100 bases:

>100_bases
GTTTGAGCGAGTGGTTTATCAACTTGTGGTTACAATTTTACCAAATTTTGAGTATTATATTGTGTTTGAAACTCTTAATT
TGGAATTTAAGGAGCCTTCT

Downstream 100 bases:

>100_bases
CATTAAAGAATTGTTTTAAGGAATAATCAATGGAAAAATATCATAGCGACCAAGAATACGAAGAAATCATCACCGACCAA
TTAGGCGATATGCAATTAAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MKVNFFATCLGAAIYSNASLNAIKLLRKENLEVVFKKDQTCCGQPSYNSGYYEETKKVVLYNIKLYSNNDYPIILPSGSC
TGMMRHDYLELFEGHAEFNMVKDFCSRVYELSEFLDKKLQVKYEDKGEPLKITWHSNCHALRVAKVIDSAKNLIRQLKNV
ELIELEKEEECCGFGGTFSVKEPEISAVMVKEKIKDIESRQVDVIVSADAGCLMNISTAMQKMGSLTKPMHFYDFLASRL
GL

Sequences:

>Translated_242_residues
MKVNFFATCLGAAIYSNASLNAIKLLRKENLEVVFKKDQTCCGQPSYNSGYYEETKKVVLYNIKLYSNNDYPIILPSGSC
TGMMRHDYLELFEGHAEFNMVKDFCSRVYELSEFLDKKLQVKYEDKGEPLKITWHSNCHALRVAKVIDSAKNLIRQLKNV
ELIELEKEEECCGFGGTFSVKEPEISAVMVKEKIKDIESRQVDVIVSADAGCLMNISTAMQKMGSLTKPMHFYDFLASRL
GL
>Mature_242_residues
MKVNFFATCLGAAIYSNASLNAIKLLRKENLEVVFKKDQTCCGQPSYNSGYYEETKKVVLYNIKLYSNNDYPIILPSGSC
TGMMRHDYLELFEGHAEFNMVKDFCSRVYELSEFLDKKLQVKYEDKGEPLKITWHSNCHALRVAKVIDSAKNLIRQLKNV
ELIELEKEEECCGFGGTFSVKEPEISAVMVKEKIKDIESRQVDVIVSADAGCLMNISTAMQKMGSLTKPMHFYDFLASRL
GL

Specific function: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lutA/ykgE family [H]

Homologues:

Organism=Escherichia coli, GI1786497, Length=241, Percent_Identity=36.9294605809129, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1788576, Length=235, Percent_Identity=23.4042553191489, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004017
- InterPro:   IPR022822 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: NA

Molecular weight: Translated: 27493; Mature: 27493

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVNFFATCLGAAIYSNASLNAIKLLRKENLEVVFKKDQTCCGQPSYNSGYYEETKKVVL
CCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHCCCEEEE
YNIKLYSNNDYPIILPSGSCTGMMRHDYLELFEGHAEFNMVKDFCSRVYELSEFLDKKLQ
EEEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEE
VKYEDKGEPLKITWHSNCHALRVAKVIDSAKNLIRQLKNVELIELEKEEECCGFGGTFSV
EEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHCCCCCCCCC
KEPEISAVMVKEKIKDIESRQVDVIVSADAGCLMNISTAMQKMGSLTKPMHFYDFLASRL
CCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEHHHHHHHHHCCCCCCHHHHHHHHHHH
GL
CC
>Mature Secondary Structure
MKVNFFATCLGAAIYSNASLNAIKLLRKENLEVVFKKDQTCCGQPSYNSGYYEETKKVVL
CCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHCCCEEEE
YNIKLYSNNDYPIILPSGSCTGMMRHDYLELFEGHAEFNMVKDFCSRVYELSEFLDKKLQ
EEEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEE
VKYEDKGEPLKITWHSNCHALRVAKVIDSAKNLIRQLKNVELIELEKEEECCGFGGTFSV
EEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHCCCCCCCCC
KEPEISAVMVKEKIKDIESRQVDVIVSADAGCLMNISTAMQKMGSLTKPMHFYDFLASRL
CCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEHHHHHHHHHCCCCCCHHHHHHHHHHH
GL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]