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The map label for this gene is lspA [H]

Identifier: 108562500

GI number: 108562500

Start: 75980

End: 76453

Strand: Reverse

Name: lspA [H]

Synonym: HPAG1_0075

Alternate gene names: 108562500

Gene position: 76453-75980 (Counterclockwise)

Preceding gene: 108562501

Following gene: 108562499

Centisome position: 4.79

GC content: 36.92

Gene sequence:

>474_bases
GTGCTAAAAACCACTAAAAAAAGCCTGTTGGTTTTTATGGGGGGTTTTTTTCTTATTTTTGGTGTGGATCAAGCGATTAA
ATACGCTATTTTAGAGGGGTTTCGCTATGAAAGTTTGATGGTAGATATTGTTTTGGTGTTCAATAAAGGCGTGGCGTTTT
CGTTGCTCAGTTTTTTAGAGGGGGGTTTGAAATACTTGCAAATCCTTTTGATTTTAGGGCTTTTTATCTTTTTGATACGC
CAAATTGAGCTTTTTAAAACCCATGCGATAGAGTTTGGCATGGTGTTTGGCGCTGGGGTTTCTAATGTTTTAGACCGGTT
TGTGCATGGGGGCGTGGTGGATTATGTGTATTATCATTATGGCTTTGATTTTGCCATTTTTAATTTCGCTGATGTCATGA
TAGATGTGGGCGTGGGCGTTTTATTGTTAAGACAATTCTTTTTTAAGCAAAAACAAAACAAAATTAAGGCATAA

Upstream 100 bases:

>100_bases
GTGGCACTGAAAACAAATTGCGAATCCTTTTAGAAGCTAAAGATGAAAAACTTTTAGAATCCAAAATGCAAGAATTAAAA
GAGTTTTTTGAAGGGCATTT

Downstream 100 bases:

>100_bases
TCACTCTTTTTAAAATAAAAGGTCGCGTAGCTCAGTTGGTAGAGCACTACCTTGACATGGTAGTGGCCGCTGGTTCAAGT
CCAGTCGTGGCCACCATTAT

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MLKTTKKSLLVFMGGFFLIFGVDQAIKYAILEGFRYESLMVDIVLVFNKGVAFSLLSFLEGGLKYLQILLILGLFIFLIR
QIELFKTHAIEFGMVFGAGVSNVLDRFVHGGVVDYVYYHYGFDFAIFNFADVMIDVGVGVLLLRQFFFKQKQNKIKA

Sequences:

>Translated_157_residues
MLKTTKKSLLVFMGGFFLIFGVDQAIKYAILEGFRYESLMVDIVLVFNKGVAFSLLSFLEGGLKYLQILLILGLFIFLIR
QIELFKTHAIEFGMVFGAGVSNVLDRFVHGGVVDYVYYHYGFDFAIFNFADVMIDVGVGVLLLRQFFFKQKQNKIKA
>Mature_157_residues
MLKTTKKSLLVFMGGFFLIFGVDQAIKYAILEGFRYESLMVDIVLVFNKGVAFSLLSFLEGGLKYLQILLILGLFIFLIR
QIELFKTHAIEFGMVFGAGVSNVLDRFVHGGVVDYVYYHYGFDFAIFNFADVMIDVGVGVLLLRQFFFKQKQNKIKA

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 17896; Mature: 17896

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKTTKKSLLVFMGGFFLIFGVDQAIKYAILEGFRYESLMVDIVLVFNKGVAFSLLSFLE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHH
GGLKYLQILLILGLFIFLIRQIELFKTHAIEFGMVFGAGVSNVLDRFVHGGVVDYVYYHY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHH
GFDFAIFNFADVMIDVGVGVLLLRQFFFKQKQNKIKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLKTTKKSLLVFMGGFFLIFGVDQAIKYAILEGFRYESLMVDIVLVFNKGVAFSLLSFLE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHH
GGLKYLQILLILGLFIFLIRQIELFKTHAIEFGMVFGAGVSNVLDRFVHGGVVDYVYYHY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHH
GFDFAIFNFADVMIDVGVGVLLLRQFFFKQKQNKIKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]