Click here to switch to the map view.

The map label for this gene is dhaT [H]

Identifier: 107023087

GI number: 107023087

Start: 1709153

End: 1710319

Strand: Reverse

Name: dhaT [H]

Synonym: Bcen_1536

Alternate gene names: 107023087

Gene position: 1710319-1709153 (Counterclockwise)

Preceding gene: 107023088

Following gene: 107023086

Centisome position: 51.91

GC content: 64.87

Gene sequence:

>1167_bases
ATGACGACTTACCATTTCCAGACAGTCAGGCACATCGTCCACGGTGCAGGCAGCCTCGCCACGCTTCCCGACAAGCTCGC
GCTGCTCGATACGCCGGTCAAGCGCATCGCGCTGATCACGCAACCGTCGATGGAAGCGCTCGGCATCGTCGATCGCGTGA
TCGAATCGCTCGACGCGAAGGACGTCGACGTGCGCATCATTCGCGGCGTCGAGCCGGAGCCGACCATCGGCAACGTCGAG
ACGGTGTTCAACGAGCAGATCGCGCCGTTTGCGCCGCAGGCGATCCTTTCGATCGGCGGCGGCAGCGTGCTCGACGCGGC
GAAACTGTTCGCGGTCCGGCTCACCAACGACGAGCCGCTGCGGAACTGGCTCGGCATCGACCTGATCAAGCACCCCGGCG
TGCCGATGATCCTGGTGCCGACGACGGCCGGCACCGGCTCCGAGGTCACGCCGAACGCAATCGTGACGCTGCCGGACGAA
TCGTTGAAGGTCGGTATCGTCAGCCGTCACCTGCTGCCGCAGATCGTCATTCTGGACCCCGAACTGACGCTCGGCCTGCC
GAAGCCGATCACCGCCGCGACCGGCATGGATGCGTTCGTGCACGCACTCGAATCGTACATTTCGACGAAGGCGAACCCGA
TCAGCGACATGTACGCGATGGAGTCGATGCGCCTGATCGGCGCGAACATCGTCGACGCGTATGAAAACGGCCAGTCACTG
AAGGCGCGCGAGGCGATGATGCTCGGGTCGATGTATGGCGGTCTCGCGCTCACCGCCGCCGGTACCGCTGCGGTACATGC
GCTCGCGTACCCGCTCGGCGGAATGTTCAACGTCACGCACGGCGTCGCGAACGCGATGCTGCTGCCGCACGTGATGGCGT
TCAACCTCGATGCGATCGAAGACCGGCTGGCGAACGTGGCGCGCGCACTCGATCTCGCGTCGAAAGCCGACACGGACGCC
GACGCGGCCCGCAAGCTGATCGACAAGATGGAGGCGTGGACCGCAGCCGTCGACATACCCCAGGATCTGCGCAAGTTCGG
CGTGTCCGAAGCACATCTCGACGCGCTCGCGGTTGCCGCATCGAAGGTCAAGCGCCTGCTCGGCAACAACCCGAAGGCGC
TCACGCTCGACGACATGAAGTCCATCTACCGGCGCCTGCTGCCGTGA

Upstream 100 bases:

>100_bases
TCGCCCGCGCAGCCGCTCGATGCCCAGGCCCGCGAGCGCCTCGCGCAAGCGCTCTCCGTCTACCGCGACGCCGCGCGCGG
CCACTGAAACAGGTCTCAGC

Downstream 100 bases:

>100_bases
ACGCGCTCGCCCCGCACGCAGCACGGCTGCTGATCGTCGCCGACGACCTGTCGGGCGCGGCCGACTGCGCGGTTGCCGGG
TTGCGTCACGGCCTGACGGC

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: 1,3-propanediol oxidoreductase; 3-hydroxypropionaldehyde reductase [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MTTYHFQTVRHIVHGAGSLATLPDKLALLDTPVKRIALITQPSMEALGIVDRVIESLDAKDVDVRIIRGVEPEPTIGNVE
TVFNEQIAPFAPQAILSIGGGSVLDAAKLFAVRLTNDEPLRNWLGIDLIKHPGVPMILVPTTAGTGSEVTPNAIVTLPDE
SLKVGIVSRHLLPQIVILDPELTLGLPKPITAATGMDAFVHALESYISTKANPISDMYAMESMRLIGANIVDAYENGQSL
KAREAMMLGSMYGGLALTAAGTAAVHALAYPLGGMFNVTHGVANAMLLPHVMAFNLDAIEDRLANVARALDLASKADTDA
DAARKLIDKMEAWTAAVDIPQDLRKFGVSEAHLDALAVAASKVKRLLGNNPKALTLDDMKSIYRRLLP

Sequences:

>Translated_388_residues
MTTYHFQTVRHIVHGAGSLATLPDKLALLDTPVKRIALITQPSMEALGIVDRVIESLDAKDVDVRIIRGVEPEPTIGNVE
TVFNEQIAPFAPQAILSIGGGSVLDAAKLFAVRLTNDEPLRNWLGIDLIKHPGVPMILVPTTAGTGSEVTPNAIVTLPDE
SLKVGIVSRHLLPQIVILDPELTLGLPKPITAATGMDAFVHALESYISTKANPISDMYAMESMRLIGANIVDAYENGQSL
KAREAMMLGSMYGGLALTAAGTAAVHALAYPLGGMFNVTHGVANAMLLPHVMAFNLDAIEDRLANVARALDLASKADTDA
DAARKLIDKMEAWTAAVDIPQDLRKFGVSEAHLDALAVAASKVKRLLGNNPKALTLDDMKSIYRRLLP
>Mature_387_residues
TTYHFQTVRHIVHGAGSLATLPDKLALLDTPVKRIALITQPSMEALGIVDRVIESLDAKDVDVRIIRGVEPEPTIGNVET
VFNEQIAPFAPQAILSIGGGSVLDAAKLFAVRLTNDEPLRNWLGIDLIKHPGVPMILVPTTAGTGSEVTPNAIVTLPDES
LKVGIVSRHLLPQIVILDPELTLGLPKPITAATGMDAFVHALESYISTKANPISDMYAMESMRLIGANIVDAYENGQSLK
AREAMMLGSMYGGLALTAAGTAAVHALAYPLGGMFNVTHGVANAMLLPHVMAFNLDAIEDRLANVARALDLASKADTDAD
AARKLIDKMEAWTAAVDIPQDLRKFGVSEAHLDALAVAASKVKRLLGNNPKALTLDDMKSIYRRLLP

Specific function: Most active with substrates containing two primary alcohol groups separated by one or two carbon atoms. In the physiological direction, 3-hydroxypropionaldehyde is the preferred substrate [H]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=425, Percent_Identity=27.0588235294118, Blast_Score=118, Evalue=9e-27,
Organism=Escherichia coli, GI48994951, Length=384, Percent_Identity=35.9375, Blast_Score=224, Evalue=9e-60,
Organism=Escherichia coli, GI1789163, Length=375, Percent_Identity=31.7333333333333, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI87082107, Length=351, Percent_Identity=32.7635327635328, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1787493, Length=380, Percent_Identity=30.7894736842105, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1789386, Length=406, Percent_Identity=27.5862068965517, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17537053, Length=432, Percent_Identity=25.462962962963, Blast_Score=130, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6321181, Length=348, Percent_Identity=34.1954022988506, Blast_Score=206, Evalue=7e-54,
Organism=Drosophila melanogaster, GI24657991, Length=398, Percent_Identity=27.6381909547739, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.202 [H]

Molecular weight: Translated: 41434; Mature: 41303

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00913 ADH_IRON_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTYHFQTVRHIVHGAGSLATLPDKLALLDTPVKRIALITQPSMEALGIVDRVIESLDAK
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHEEEECCCCHHHHHHHHHHHHHCCCC
DVDVRIIRGVEPEPTIGNVETVFNEQIAPFAPQAILSIGGGSVLDAAKLFAVRLTNDEPL
CCCEEEEECCCCCCCCCCHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHEEEEEECCCHHH
RNWLGIDLIKHPGVPMILVPTTAGTGSEVTPNAIVTLPDESLKVGIVSRHLLPQIVILDP
HHHHCCHHHCCCCCCEEEEECCCCCCCCCCCCCEEECCCCCEEEHHHHHHHCCEEEEECC
ELTLGLPKPITAATGMDAFVHALESYISTKANPISDMYAMESMRLIGANIVDAYENGQSL
CCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCH
KAREAMMLGSMYGGLALTAAGTAAVHALAYPLGGMFNVTHGVANAMLLPHVMAFNLDAIE
HHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHH
DRLANVARALDLASKADTDADAARKLIDKMEAWTAAVDIPQDLRKFGVSEAHLDALAVAA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHH
SKVKRLLGNNPKALTLDDMKSIYRRLLP
HHHHHHHCCCCCEEEHHHHHHHHHHHCC
>Mature Secondary Structure 
TTYHFQTVRHIVHGAGSLATLPDKLALLDTPVKRIALITQPSMEALGIVDRVIESLDAK
CCCHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHEEEECCCCHHHHHHHHHHHHHCCCC
DVDVRIIRGVEPEPTIGNVETVFNEQIAPFAPQAILSIGGGSVLDAAKLFAVRLTNDEPL
CCCEEEEECCCCCCCCCCHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHEEEEEECCCHHH
RNWLGIDLIKHPGVPMILVPTTAGTGSEVTPNAIVTLPDESLKVGIVSRHLLPQIVILDP
HHHHCCHHHCCCCCCEEEEECCCCCCCCCCCCCEEECCCCCEEEHHHHHHHCCEEEEECC
ELTLGLPKPITAATGMDAFVHALESYISTKANPISDMYAMESMRLIGANIVDAYENGQSL
CCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCH
KAREAMMLGSMYGGLALTAAGTAAVHALAYPLGGMFNVTHGVANAMLLPHVMAFNLDAIE
HHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHH
DRLANVARALDLASKADTDADAARKLIDKMEAWTAAVDIPQDLRKFGVSEAHLDALAVAA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHH
SKVKRLLGNNPKALTLDDMKSIYRRLLP
HHHHHHHCCCCCEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7721705 [H]