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The map label for this gene is tcyB [H]

Identifier: 107023049

GI number: 107023049

Start: 1659858

End: 1660544

Strand: Reverse

Name: tcyB [H]

Synonym: Bcen_1497

Alternate gene names: 107023049

Gene position: 1660544-1659858 (Counterclockwise)

Preceding gene: 107023050

Following gene: 107023048

Centisome position: 50.4

GC content: 69.0

Gene sequence:

>687_bases
ATGAGCTACCAGCTTCAATTCGGCGAACTGTCCGAGTACGTCGGCGTGTTCGCGAGCGGCGCGGCGATCACGCTCGCGCT
GACCGCGGTCGCGACCGTGCTCGGCGTGGCGGTCGGCGTGCTCGGCGCGGCCGCGTACAGCGCCGACGCGCGGGCGGCCG
TGCGCTTGCGCCCGCTGATCGGCGCGTACGTCGAGGCGATTCGCAATACGCCGTTCGTCGTCCAGCTGTTCTTCATCTTC
TTCGGCTTGCCGGCGCTCGGCGTGCACATCGACGAATACACGGCCGCGATCCTCGCGATGACGCTCAATCTCGGCGCGTA
CTCGGTCGAGATCGTGCGCGCGGGCGTGGCCGCCGTGCCGAAAGGGCATCTGGAGGCCGCGTCCGCGCTGGCGATGTCGC
GCGCGCAGATGCTGCGCCACGTCGTGCTGCCGCAGGCGCTCGCCAAGGTGTTTCCCGCGCTGTCGAGCCAGATCGTGATC
ACGATGCTCGGCTCGGCCGTCGTGTCGCAGATCTCGGTGGCCGACCTGACCTACGCGGCCAGCTACATTCAGTCGCGCAA
CTTTCGCGCGTTCGAGACGTACTTCGTGATCACGCTCGCGTATCTGGCGATGGCGCTGCTGCTGCGCGCCACCCTCGGCG
CGATGGGCCGCCGCCTGTTCACCCGCCGCGTGCGAGGTGCGCGATGA

Upstream 100 bases:

>100_bases
CCGGACTGTGACGCATCGCCGTGTCGCCTGATACGTCGCCGCGGCCGGGGTGCCCGGCGTGGCGCGTGTCGTTGTCCGAA
CCCGAATTCATCTCCTTCCC

Downstream 100 bases:

>100_bases
CCGATTTCACATTGGGGCAGATTCTCGCGAACCTGCTGCTGGCCGCGCGCTGGACGATCGTGCTGTCGATCGTGTCGTTC
GTGACGGGCGGCCTCGTCGG

Product: amino acid ABC transporter permease

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MSYQLQFGELSEYVGVFASGAAITLALTAVATVLGVAVGVLGAAAYSADARAAVRLRPLIGAYVEAIRNTPFVVQLFFIF
FGLPALGVHIDEYTAAILAMTLNLGAYSVEIVRAGVAAVPKGHLEAASALAMSRAQMLRHVVLPQALAKVFPALSSQIVI
TMLGSAVVSQISVADLTYAASYIQSRNFRAFETYFVITLAYLAMALLLRATLGAMGRRLFTRRVRGAR

Sequences:

>Translated_228_residues
MSYQLQFGELSEYVGVFASGAAITLALTAVATVLGVAVGVLGAAAYSADARAAVRLRPLIGAYVEAIRNTPFVVQLFFIF
FGLPALGVHIDEYTAAILAMTLNLGAYSVEIVRAGVAAVPKGHLEAASALAMSRAQMLRHVVLPQALAKVFPALSSQIVI
TMLGSAVVSQISVADLTYAASYIQSRNFRAFETYFVITLAYLAMALLLRATLGAMGRRLFTRRVRGAR
>Mature_227_residues
SYQLQFGELSEYVGVFASGAAITLALTAVATVLGVAVGVLGAAAYSADARAAVRLRPLIGAYVEAIRNTPFVVQLFFIFF
GLPALGVHIDEYTAAILAMTLNLGAYSVEIVRAGVAAVPKGHLEAASALAMSRAQMLRHVVLPQALAKVFPALSSQIVIT
MLGSAVVSQISVADLTYAASYIQSRNFRAFETYFVITLAYLAMALLLRATLGAMGRRLFTRRVRGAR

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787030, Length=223, Percent_Identity=33.1838565022422, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788226, Length=216, Percent_Identity=30.0925925925926, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1788646, Length=221, Percent_Identity=29.8642533936652, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1786874, Length=212, Percent_Identity=29.2452830188679, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1787087, Length=235, Percent_Identity=26.8085106382979, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786873, Length=214, Percent_Identity=28.5046728971963, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788645, Length=202, Percent_Identity=30.1980198019802, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI48994930, Length=133, Percent_Identity=32.3308270676692, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082239, Length=160, Percent_Identity=32.5, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787086, Length=174, Percent_Identity=23.5632183908046, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24220; Mature: 24089

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQLQFGELSEYVGVFASGAAITLALTAVATVLGVAVGVLGAAAYSADARAAVRLRPLI
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GAYVEAIRNTPFVVQLFFIFFGLPALGVHIDEYTAAILAMTLNLGAYSVEIVRAGVAAVP
HHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
KGHLEAASALAMSRAQMLRHVVLPQALAKVFPALSSQIVITMLGSAVVSQISVADLTYAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYIQSRNFRAFETYFVITLAYLAMALLLRATLGAMGRRLFTRRVRGAR
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SYQLQFGELSEYVGVFASGAAITLALTAVATVLGVAVGVLGAAAYSADARAAVRLRPLI
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GAYVEAIRNTPFVVQLFFIFFGLPALGVHIDEYTAAILAMTLNLGAYSVEIVRAGVAAVP
HHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
KGHLEAASALAMSRAQMLRHVVLPQALAKVFPALSSQIVITMLGSAVVSQISVADLTYAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYIQSRNFRAFETYFVITLAYLAMALLLRATLGAMGRRLFTRRVRGAR
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]