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The map label for this gene is rstB [H]

Identifier: 107022425

GI number: 107022425

Start: 945214

End: 946623

Strand: Reverse

Name: rstB [H]

Synonym: Bcen_0870

Alternate gene names: 107022425

Gene position: 946623-945214 (Counterclockwise)

Preceding gene: 107022426

Following gene: 107022420

Centisome position: 28.73

GC content: 68.09

Gene sequence:

>1410_bases
ATGCTGCGCCCGTTGCTCCGGTTGTACCTCGTCGTGATCCTGTTCGTCGGTGCGTCGATCATCTTCATCCAGCTGTCGTT
CGACCGGATCTTCTATGAACGCGGCGCGCAGGCGCAGCGCGATTCGCTGACGACCTATTCGTTCGTGCTGAACGACTACC
TCGAACGCCATCCGGGCGCGCAGCGCGAGCTCGCATTGCGCGAACTCGCGCTGCATGGCCGCGAAGGATTCGGCTTCATG
TCGATGGCCGACGCGCGTGCGCAACTGAGCGGCGCGCCGTTGCGCGATCTCGATGCCGGCAGGATCGCGATCAGCTACAA
CGGCAAGGATTACTACATGCCGCTCGCGGACGGCTCGGTGCTGCATGCCCGCCCGATCGAAGCGCCCGACCTCGACATCC
GGATCTATGCGTACATGCTGCTCGCGCTCGCGACGCTGTTCGCGGTCGTGCTGTGGATTCACTATCACTGGCGCGACATT
CGCCGGCTGCAGGATGCCGCGCGCGCGTTCGGCGCCGGAATGCTGTCGACACGCGTGAAGCTGTCGGGCAAGTCGAACAT
CTACGAGCTGTCGCAGCAGTTCAACGACATGGCCGCGCGTATCGAGGCGTCGATCAAGCAGCAGCGCGAAATGATGCACG
GCATCTCGCATGAACTGAAAACGCCGCTCGCCCGGCTCGAATTCGGGCTCGCGCTGCTCGCCGACGCCGACGAGACGGGC
CGGATGCGCGACGCGCTGCGACGCGACGTGCGCGAACTCGACGAGCTCGTCACCGAGTTGCTGACGATCGGCCGGCTCGA
ACAGGGTGCGAGCGAGCTCGCGCCGATGGAAGTCGTCGTCGATGCGCTGATCGACAGCGTCGCCGGCAACGTCGCGGACG
ACATCGCCGATCGCGGCATCGCGCTCGACGTGTCGACGTTCGACGCGCCCGCGACCCACGTCTGCGATCCGAAGCTCGTC
GCCCGCGCGCTGCTGAACCTGATTCGCAACGGCGCCCGCTATGCGTCGCGCAAGGTCGTGCTGGCCGCGACCCGCGACCC
GTCCGGCGCGCTCGTGCTGAGCGTCGACGACGATGGCCCCGGCATTCCGGCCGCCGAACGCGCCCGCGTGTTCGAGCCGT
TCCAGCGGCTGGATTCGAGCCGCGACCGTCAGACCGGCGGTTTCGGGCTCGGGCTCGCGATCGTGCGGCGCGTCGCGCAG
GTGCACGGCGGCGACGTGCGGCTCGAGGATTCGCCGCTCGGCGGCGCGCGCTTCGTGATCACGCTGCCCGTGCGTGCGCT
GCCGGACAGTCTGTTCGACGTCGCGCAGCACGTGGAAAGCACGCATGCCGATGCGCGCCGCCGCAGCGGCACGGGACGGT
CGTCCCGCTTCGATGAAAACGGCGGCGGGCGCCTACCCGCCCCCGCGTGA

Upstream 100 bases:

>100_bases
GCTGCGCCGCCGCTTCGAGGATGCGTCATCGGAGCCGCACAAGATCAAGACGATCTGGGGTCGCGGCTACCTGTTCAGCC
CTTCTGCGTGGGACGAGTAA

Downstream 100 bases:

>100_bases
CCGCGCCTTCGCTCAGCGCCGGCGCAACAGCGCGACGAAGAACAGGCTGCCGAACAGCGCGGTCACGATGCCGATCGGCA
GGTCCTCCGGCGCCGCGAGC

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MLRPLLRLYLVVILFVGASIIFIQLSFDRIFYERGAQAQRDSLTTYSFVLNDYLERHPGAQRELALRELALHGREGFGFM
SMADARAQLSGAPLRDLDAGRIAISYNGKDYYMPLADGSVLHARPIEAPDLDIRIYAYMLLALATLFAVVLWIHYHWRDI
RRLQDAARAFGAGMLSTRVKLSGKSNIYELSQQFNDMAARIEASIKQQREMMHGISHELKTPLARLEFGLALLADADETG
RMRDALRRDVRELDELVTELLTIGRLEQGASELAPMEVVVDALIDSVAGNVADDIADRGIALDVSTFDAPATHVCDPKLV
ARALLNLIRNGARYASRKVVLAATRDPSGALVLSVDDDGPGIPAAERARVFEPFQRLDSSRDRQTGGFGLGLAIVRRVAQ
VHGGDVRLEDSPLGGARFVITLPVRALPDSLFDVAQHVESTHADARRRSGTGRSSRFDENGGGRLPAPA

Sequences:

>Translated_469_residues
MLRPLLRLYLVVILFVGASIIFIQLSFDRIFYERGAQAQRDSLTTYSFVLNDYLERHPGAQRELALRELALHGREGFGFM
SMADARAQLSGAPLRDLDAGRIAISYNGKDYYMPLADGSVLHARPIEAPDLDIRIYAYMLLALATLFAVVLWIHYHWRDI
RRLQDAARAFGAGMLSTRVKLSGKSNIYELSQQFNDMAARIEASIKQQREMMHGISHELKTPLARLEFGLALLADADETG
RMRDALRRDVRELDELVTELLTIGRLEQGASELAPMEVVVDALIDSVAGNVADDIADRGIALDVSTFDAPATHVCDPKLV
ARALLNLIRNGARYASRKVVLAATRDPSGALVLSVDDDGPGIPAAERARVFEPFQRLDSSRDRQTGGFGLGLAIVRRVAQ
VHGGDVRLEDSPLGGARFVITLPVRALPDSLFDVAQHVESTHADARRRSGTGRSSRFDENGGGRLPAPA
>Mature_469_residues
MLRPLLRLYLVVILFVGASIIFIQLSFDRIFYERGAQAQRDSLTTYSFVLNDYLERHPGAQRELALRELALHGREGFGFM
SMADARAQLSGAPLRDLDAGRIAISYNGKDYYMPLADGSVLHARPIEAPDLDIRIYAYMLLALATLFAVVLWIHYHWRDI
RRLQDAARAFGAGMLSTRVKLSGKSNIYELSQQFNDMAARIEASIKQQREMMHGISHELKTPLARLEFGLALLADADETG
RMRDALRRDVRELDELVTELLTIGRLEQGASELAPMEVVVDALIDSVAGNVADDIADRGIALDVSTFDAPATHVCDPKLV
ARALLNLIRNGARYASRKVVLAATRDPSGALVLSVDDDGPGIPAAERARVFEPFQRLDSSRDRQTGGFGLGLAIVRRVAQ
VHGGDVRLEDSPLGGARFVITLPVRALPDSLFDVAQHVESTHADARRRSGTGRSSRFDENGGGRLPAPA

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=294, Percent_Identity=37.4149659863946, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI1790346, Length=265, Percent_Identity=35.4716981132075, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1789808, Length=290, Percent_Identity=30.6896551724138, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788393, Length=272, Percent_Identity=31.25, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=30.5785123966942, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1786600, Length=241, Percent_Identity=28.6307053941909, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786783, Length=298, Percent_Identity=30.2013422818792, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1788713, Length=305, Percent_Identity=24.9180327868852, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=23.75, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI87081816, Length=279, Percent_Identity=27.2401433691756, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082128, Length=296, Percent_Identity=27.027027027027, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1789149, Length=230, Percent_Identity=28.2608695652174, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1790551, Length=269, Percent_Identity=27.8810408921933, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=27.7777777777778, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790861, Length=238, Percent_Identity=28.9915966386555, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787374, Length=298, Percent_Identity=23.8255033557047, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788549, Length=247, Percent_Identity=24.6963562753036, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI48994928, Length=229, Percent_Identity=25.3275109170306, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789403, Length=235, Percent_Identity=26.3829787234043, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51621; Mature: 51621

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRPLLRLYLVVILFVGASIIFIQLSFDRIFYERGAQAQRDSLTTYSFVLNDYLERHPGA
CCHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCC
QRELALRELALHGREGFGFMSMADARAQLSGAPLRDLDAGRIAISYNGKDYYMPLADGSV
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEEECCCCCE
LHARPIEAPDLDIRIYAYMLLALATLFAVVLWIHYHWRDIRRLQDAARAFGAGMLSTRVK
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEE
LSGKSNIYELSQQFNDMAARIEASIKQQREMMHGISHELKTPLARLEFGLALLADADETG
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCH
RMRDALRRDVRELDELVTELLTIGRLEQGASELAPMEVVVDALIDSVAGNVADDIADRGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
ALDVSTFDAPATHVCDPKLVARALLNLIRNGARYASRKVVLAATRDPSGALVLSVDDDGP
EEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHCCEEEEEEECCCCCEEEEEECCCCC
GIPAAERARVFEPFQRLDSSRDRQTGGFGLGLAIVRRVAQVHGGDVRLEDSPLGGARFVI
CCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEE
TLPVRALPDSLFDVAQHVESTHADARRRSGTGRSSRFDENGGGRLPAPA
EECHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLRPLLRLYLVVILFVGASIIFIQLSFDRIFYERGAQAQRDSLTTYSFVLNDYLERHPGA
CCHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCC
QRELALRELALHGREGFGFMSMADARAQLSGAPLRDLDAGRIAISYNGKDYYMPLADGSV
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEEECCCCCE
LHARPIEAPDLDIRIYAYMLLALATLFAVVLWIHYHWRDIRRLQDAARAFGAGMLSTRVK
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEE
LSGKSNIYELSQQFNDMAARIEASIKQQREMMHGISHELKTPLARLEFGLALLADADETG
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCH
RMRDALRRDVRELDELVTELLTIGRLEQGASELAPMEVVVDALIDSVAGNVADDIADRGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
ALDVSTFDAPATHVCDPKLVARALLNLIRNGARYASRKVVLAATRDPSGALVLSVDDDGP
EEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHCCEEEEEEECCCCCEEEEEECCCCC
GIPAAERARVFEPFQRLDSSRDRQTGGFGLGLAIVRRVAQVHGGDVRLEDSPLGGARFVI
CCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEE
TLPVRALPDSLFDVAQHVESTHADARRRSGTGRSSRFDENGGGRLPAPA
EECHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]