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The map label for this gene is galE [H]

Identifier: 107021968

GI number: 107021968

Start: 453587

End: 454609

Strand: Reverse

Name: galE [H]

Synonym: Bcen_0410

Alternate gene names: 107021968

Gene position: 454609-453587 (Counterclockwise)

Preceding gene: 107021969

Following gene: 107021967

Centisome position: 13.8

GC content: 67.06

Gene sequence:

>1023_bases
ATGACCGCTAAAGGCACCATCCTCGTTACCGGCGGCGCGGGCTATATCGGCTCGCACACGGCCGTCGAGCTGCTCGACAA
CGGCTACGACGTCGTGATCGTCGACAACCTCGTCAACAGCAAGGCCGAATCGGTGCGCCGGATCGAGCGGATCACGGGCA
AGACGCCCGCGTTCCACCAGGTCGACGTGTGCGACGAAGCCGCGCTCGCGAAGGTATTCGACGCGCATCCGATCACCGGC
ACGATTCACTTCGCGGCGCTCAAGGCCGTCGGCGAATCGGTCGCGAAGCCGCTCGAGTACTACCAGAACAACATCGGCGG
ACTGCTCGCCGTGCTGAAGGTCATGCGCGAGCGCAACGTCAGGCAGTTCGTGTTCAGCTCGTCCGCGACCGTGTACGGCG
TGCCCGAGCGCTCGCCGATCGACGAATCGTTCCCGCTGTCCGCGACGAACCCGTACGGCCAGTCGAAGCTGATCGCCGAG
CAGATCCTGCGCGATCTCGAAGTCTCGGACCCGTCGTGGCGGATCGCGACGCTGCGCTACTTCAACCCGGTCGGCGCGCA
CGCGAGCGGGCTGATCGGCGAGGACCCGGCCGGCATCCCGAACAACCTGATGCCGTACGTCGCGCAGGTCGCGGTCGGCA
AGCTCGAAAAGCTGCGCGTGTTCGGCTCCGACTACCCGACGCCGGACGGCACCGGCGTGCGCGACTACATCCACGTCGTC
GATCTCGCGAAGGGGCACATCGCCGCGCTCGACGCGCTCGCGAAGCGCGACGCGAGCTTCGTCGTGAACCTCGGCACCGG
CCAGGGCTACAGCGTGCTGGAAGTCGTGCGCGCGTTCGAGAAGGCGTCGGGCCGCCCGGTGCCGTACGAACTCGTCGCGC
GCCGCCCGGGCGACATCGCCGAGTGCTATGCGAACCCGCAGGCCGCGGTCGACATCATCGGCTGGCGTGCGACGCTCGGT
ATCGAAGAGATGTGTGCCGACCACTGGCGATGGCAGGAGGGGAACCCGCGCGGTTTTGTATAA

Upstream 100 bases:

>100_bases
CAAGGTCGCGGCGGAATTCGACGAACAGCAGGTCGTCGAACGCTACAGGGAGACCATCCATTCGTTGACAGGATTCACAC
TCTGAAGGAGCGCATCAGCA

Downstream 100 bases:

>100_bases
TCCGCTGTCCATTTTCCGAGCGATCCCATGCTCAGCTTCGCGTCCGGCTTCATCGTCTCCTTGCTCGTCACGCTGTTCAT
CGTGCGCTACGCGCACCTTC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTAKGTILVTGGAGYIGSHTAVELLDNGYDVVIVDNLVNSKAESVRRIERITGKTPAFHQVDVCDEAALAKVFDAHPITG
TIHFAALKAVGESVAKPLEYYQNNIGGLLAVLKVMRERNVRQFVFSSSATVYGVPERSPIDESFPLSATNPYGQSKLIAE
QILRDLEVSDPSWRIATLRYFNPVGAHASGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSDYPTPDGTGVRDYIHVV
DLAKGHIAALDALAKRDASFVVNLGTGQGYSVLEVVRAFEKASGRPVPYELVARRPGDIAECYANPQAAVDIIGWRATLG
IEEMCADHWRWQEGNPRGFV

Sequences:

>Translated_340_residues
MTAKGTILVTGGAGYIGSHTAVELLDNGYDVVIVDNLVNSKAESVRRIERITGKTPAFHQVDVCDEAALAKVFDAHPITG
TIHFAALKAVGESVAKPLEYYQNNIGGLLAVLKVMRERNVRQFVFSSSATVYGVPERSPIDESFPLSATNPYGQSKLIAE
QILRDLEVSDPSWRIATLRYFNPVGAHASGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSDYPTPDGTGVRDYIHVV
DLAKGHIAALDALAKRDASFVVNLGTGQGYSVLEVVRAFEKASGRPVPYELVARRPGDIAECYANPQAAVDIIGWRATLG
IEEMCADHWRWQEGNPRGFV
>Mature_339_residues
TAKGTILVTGGAGYIGSHTAVELLDNGYDVVIVDNLVNSKAESVRRIERITGKTPAFHQVDVCDEAALAKVFDAHPITGT
IHFAALKAVGESVAKPLEYYQNNIGGLLAVLKVMRERNVRQFVFSSSATVYGVPERSPIDESFPLSATNPYGQSKLIAEQ
ILRDLEVSDPSWRIATLRYFNPVGAHASGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSDYPTPDGTGVRDYIHVVD
LAKGHIAALDALAKRDASFVVNLGTGQGYSVLEVVRAFEKASGRPVPYELVARRPGDIAECYANPQAAVDIIGWRATLGI
EEMCADHWRWQEGNPRGFV

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=57.3529411764706, Blast_Score=416, Evalue=1e-116,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=57.3529411764706, Blast_Score=416, Evalue=1e-116,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=57.3529411764706, Blast_Score=416, Evalue=1e-116,
Organism=Homo sapiens, GI7657641, Length=274, Percent_Identity=28.1021897810219, Blast_Score=94, Evalue=1e-19,
Organism=Escherichia coli, GI1786974, Length=334, Percent_Identity=55.9880239520958, Blast_Score=388, Evalue=1e-109,
Organism=Escherichia coli, GI48994969, Length=255, Percent_Identity=27.843137254902, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788353, Length=362, Percent_Identity=25.6906077348066, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=343, Percent_Identity=55.6851311953353, Blast_Score=390, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI71982038, Length=345, Percent_Identity=55.3623188405797, Blast_Score=389, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17568069, Length=335, Percent_Identity=23.8805970149254, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115532424, Length=339, Percent_Identity=23.598820058997, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=342, Percent_Identity=55.2631578947368, Blast_Score=375, Evalue=1e-105,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=55.9766763848396, Blast_Score=394, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36803; Mature: 36672

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKGTILVTGGAGYIGSHTAVELLDNGYDVVIVDNLVNSKAESVRRIERITGKTPAFHQ
CCCCCEEEEECCCCCCCCHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCEE
VDVCDEAALAKVFDAHPITGTIHFAALKAVGESVAKPLEYYQNNIGGLLAVLKVMRERNV
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
RQFVFSSSATVYGVPERSPIDESFPLSATNPYGQSKLIAEQILRDLEVSDPSWRIATLRY
HHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEE
FNPVGAHASGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSDYPTPDGTGVRDYIHVV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHH
DLAKGHIAALDALAKRDASFVVNLGTGQGYSVLEVVRAFEKASGRPVPYELVARRPGDIA
HHCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHH
ECYANPQAAVDIIGWRATLGIEEMCADHWRWQEGNPRGFV
HHHCCCCHHEEEEEHHHHCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TAKGTILVTGGAGYIGSHTAVELLDNGYDVVIVDNLVNSKAESVRRIERITGKTPAFHQ
CCCCEEEEECCCCCCCCHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCEE
VDVCDEAALAKVFDAHPITGTIHFAALKAVGESVAKPLEYYQNNIGGLLAVLKVMRERNV
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
RQFVFSSSATVYGVPERSPIDESFPLSATNPYGQSKLIAEQILRDLEVSDPSWRIATLRY
HHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEE
FNPVGAHASGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSDYPTPDGTGVRDYIHVV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHH
DLAKGHIAALDALAKRDASFVVNLGTGQGYSVLEVVRAFEKASGRPVPYELVARRPGDIA
HHCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHH
ECYANPQAAVDIIGWRATLGIEEMCADHWRWQEGNPRGFV
HHHCCCCHHEEEEEHHHHCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]