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The map label for this gene is coaE [H]

Identifier: 107021653

GI number: 107021653

Start: 97658

End: 98266

Strand: Reverse

Name: coaE [H]

Synonym: Bcen_0093

Alternate gene names: 107021653

Gene position: 98266-97658 (Counterclockwise)

Preceding gene: 107021654

Following gene: 107021652

Centisome position: 2.98

GC content: 68.14

Gene sequence:

>609_bases
ATGTTTTCAGTAGGACTCACGGGCGGCATCGGCAGCGGCAAGACGACCGTTGCCGACCTGTTCGGCGCCCGTGGCGCATC
GCTCGTCGATACCGACCTGATTGCCCACCGCATCACCGCACCGGGCGGCCTCGCGATGCCGGCGATCGAGCAGGCCTTCG
GCCACGGCTTCGTGGCCGCCGACGGCTCGCTCGATCGCGCGAAGATGCGCACGCTGATCTTCAGCGACGACGACGCGCGC
CGGCGCCTCGAAGCGATCACGCATCCGCTGATCCGCGCGGAGACCGATCGCGAGGCGCGCGAAGCACGGGGCCCGTACGT
GATGTTCGTCGTGCCGTTGCTCGTGGAATCAGGCACGTGGAAGGCGCGCAGCAATCGTGTGCTCGTCGTCGACTGCCCGG
TCGAAACGCAGATCGCGCGCGTGATGCGACGCAACGGTTTCACGCGCGAACAGGTCGAAGCGATCATCGCGCGCCAGGCG
ACGCGCGAAGCGCGCCTCGCTGCGGCCGACGATGTGATCGTCAACGACGCGGTCACGCCCGACGCTCTTGCCGCGCAGGT
CGATGCACTGCACCAACGCTATGTCGGATTCGCGGCCGCCGCGCACTGA

Upstream 100 bases:

>100_bases
CGCTTCGAGGAGCCGATTCCATTCGGCCCGTTCCTCGCGGCCGGCGGCGTCGCCACGCTGTTTTTCGGCACCCCTTTCTA
TGCGGCGCTCGGAGGCTGAC

Downstream 100 bases:

>100_bases
GCCTCGCACGCAATCGTGATGGTGTACGAAATTGGCGCGTTGCTAGGGTAGAGAGGGGGCATTAGAATGTCCTTCATTGT
TTCAATCCCTACCCAAGAGG

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MFSVGLTGGIGSGKTTVADLFGARGASLVDTDLIAHRITAPGGLAMPAIEQAFGHGFVAADGSLDRAKMRTLIFSDDDAR
RRLEAITHPLIRAETDREAREARGPYVMFVVPLLVESGTWKARSNRVLVVDCPVETQIARVMRRNGFTREQVEAIIARQA
TREARLAAADDVIVNDAVTPDALAAQVDALHQRYVGFAAAAH

Sequences:

>Translated_202_residues
MFSVGLTGGIGSGKTTVADLFGARGASLVDTDLIAHRITAPGGLAMPAIEQAFGHGFVAADGSLDRAKMRTLIFSDDDAR
RRLEAITHPLIRAETDREAREARGPYVMFVVPLLVESGTWKARSNRVLVVDCPVETQIARVMRRNGFTREQVEAIIARQA
TREARLAAADDVIVNDAVTPDALAAQVDALHQRYVGFAAAAH
>Mature_202_residues
MFSVGLTGGIGSGKTTVADLFGARGASLVDTDLIAHRITAPGGLAMPAIEQAFGHGFVAADGSLDRAKMRTLIFSDDDAR
RRLEAITHPLIRAETDREAREARGPYVMFVVPLLVESGTWKARSNRVLVVDCPVETQIARVMRRNGFTREQVEAIIARQA
TREARLAAADDVIVNDAVTPDALAAQVDALHQRYVGFAAAAH

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=172, Percent_Identity=40.1162790697674, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI191252795, Length=172, Percent_Identity=40.1162790697674, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI110227607, Length=192, Percent_Identity=27.0833333333333, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI110227605, Length=192, Percent_Identity=27.0833333333333, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI110227603, Length=192, Percent_Identity=27.0833333333333, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI110227601, Length=192, Percent_Identity=27.0833333333333, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI205277394, Length=192, Percent_Identity=27.0833333333333, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1786292, Length=198, Percent_Identity=50, Blast_Score=182, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17554944, Length=206, Percent_Identity=31.0679611650485, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6320402, Length=202, Percent_Identity=32.1782178217822, Blast_Score=79, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24658602, Length=172, Percent_Identity=29.0697674418605, Blast_Score=90, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24644728, Length=185, Percent_Identity=27.027027027027, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21705; Mature: 21705

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSVGLTGGIGSGKTTVADLFGARGASLVDTDLIAHRITAPGGLAMPAIEQAFGHGFVAA
CCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEE
DGSLDRAKMRTLIFSDDDARRRLEAITHPLIRAETDREAREARGPYVMFVVPLLVESGTW
CCCCCHHHHHHEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEEHHHHCCCCC
KARSNRVLVVDCPVETQIARVMRRNGFTREQVEAIIARQATREARLAAADDVIVNDAVTP
CCCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCH
DALAAQVDALHQRYVGFAAAAH
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFSVGLTGGIGSGKTTVADLFGARGASLVDTDLIAHRITAPGGLAMPAIEQAFGHGFVAA
CCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEE
DGSLDRAKMRTLIFSDDDARRRLEAITHPLIRAETDREAREARGPYVMFVVPLLVESGTW
CCCCCHHHHHHEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEEHHHHCCCCC
KARSNRVLVVDCPVETQIARVMRRNGFTREQVEAIIARQATREARLAAADDVIVNDAVTP
CCCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCH
DALAAQVDALHQRYVGFAAAAH
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA