Click here to switch to the map view.

The map label for this gene is yciC [H]

Identifier: 107021568

GI number: 107021568

Start: 6021

End: 7433

Strand: Reverse

Name: yciC [H]

Synonym: Bcen_0006

Alternate gene names: 107021568

Gene position: 7433-6021 (Counterclockwise)

Preceding gene: 107021569

Following gene: 107021566

Centisome position: 0.23

GC content: 66.24

Gene sequence:

>1413_bases
ATGCGGGCTGACGCCGCCGTTTCGCCCGTGCGCGGGCCGATCGCGCCCCGGCAGGGCGCCGCGGCCGCTTTTTCATCTCT
TCCGTTGGTGCATATCATCATGAATCCGGCAATGAAACAGCCGTTGCCCGTCACCGTGCTGTCCGGCTTCCTCGGCGCCG
GCAAGACCACGCTGCTCAACCACGTCCTCGCGAACCGCGCGGGCCTGAAAGTCGCGGTGATCGTCAACGATCTCGCGGCG
GTCAACATCGACGCGTCGCTCGTGCGCGATGCGCAGGCGCTGTCGCACGTCGAGGAACGCCTCGTCGAAATGTCGAACGG
CTGCATCTGCTGCACGCTGCGCGACGATCTGCTCGTCGAGATCCGCAACCTTGCGTCCGAAGGCCGCTTCGACGCGATCA
TGATCGAATCGACCGGTATCGCGGAGCCGATGCCGATCGCCGAAACCTTCACGTTCGTCGACGACGACGGCGCGTCGCTG
TCAGCCATCGCGCGGCTCGACACGCTCGTCACCGTGGTCGACGCGTACAACTTCCTGCGCGACTACGGCTCCGACGACGC
GCTCGCGACACGCGGCATCGCCGCGTCGGAAGACGACGACCGCACGCTCGTCGAGCTGCTGATCGAGCAGATCGAATTCT
GCGACGTGCTGGTGATCAACAAGGCCGACCTCGTCGGCGCGGACGATCTCGCCCGCCTGCAGCACATCCTCGCGCGCCTC
AATCCGCGCGCGCACCAGGTCGTCTCGACGTTCGGCAACGTGCCGCTCGACGAAGTGCTGAACACCGGCCGCTTCGATTT
CGACGAAGCCGCGAACGCGCCGGGCTGGCTCGCATCGCTCGATCACGATCACACGCATTGCGACGACCCGGACTGCCATG
ACGACCATCATGCGCACGTGCACGGCGAAGCCGACGAATTCGGCATCGGCAATTTTGTTTACCGCGCGCGCCGGCCGTTT
CACCCGGCACGGCTCTGGGCGCTGCTGCATCAGGAGTGGCCGGGCGTACTGCGCAGCAAGGGTTTCTTCTGGCTCGCGAC
GCGCAACGACATCGCAGGTTCGCTGTCGCAGGCGGGCGGCGTATGCCGGCATGGCCCGGCAGGTTTGTGGTGGGCGGCGC
AGGATCGCGCGGAATGGCCGGACGACGACGAGCTGCTCGCTGAAATCCGCACCGAATGGCTCGGCGATCTCGACGATCGC
ACGGTCGGGGATCGTCGCCAGGAACTCGTGCTGATCGGCATCGCGCTCGACGCCGATGCATGGCGCGCGAAACTCGATGC
ATGCCTGCTGACCGATGCGGAGTTCGCACTCGGTGCAGCGGGATGGGCGGCGTTCGACGATCCGTTCCCGGCGTGGGACG
TCGATTCGCACGACGACGACGATCACGGCGACACGCAGATCGTGCACGCATGA

Upstream 100 bases:

>100_bases
CACTCAGGCCGCCCAGGCCGCTCAAGCGCCTCAAGCCGCTCAGTGATTCCGCGCCGCGTCGCCGGCTGACGCCGGGCCGG
CCGCGCGCGTTTGATGCACA

Downstream 100 bases:

>100_bases
TCGCGTGGTAACGGCTTGTAAAATAACCGTTAACTTTTGCAAGAGCGGCGCGAACTGTGGCGAAAATGCCGCGCGCGCCC
AACAAAAAACCCGCCGAGAG

Product: cobalamin synthesis protein, P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MRADAAVSPVRGPIAPRQGAAAAFSSLPLVHIIMNPAMKQPLPVTVLSGFLGAGKTTLLNHVLANRAGLKVAVIVNDLAA
VNIDASLVRDAQALSHVEERLVEMSNGCICCTLRDDLLVEIRNLASEGRFDAIMIESTGIAEPMPIAETFTFVDDDGASL
SAIARLDTLVTVVDAYNFLRDYGSDDALATRGIAASEDDDRTLVELLIEQIEFCDVLVINKADLVGADDLARLQHILARL
NPRAHQVVSTFGNVPLDEVLNTGRFDFDEAANAPGWLASLDHDHTHCDDPDCHDDHHAHVHGEADEFGIGNFVYRARRPF
HPARLWALLHQEWPGVLRSKGFFWLATRNDIAGSLSQAGGVCRHGPAGLWWAAQDRAEWPDDDELLAEIRTEWLGDLDDR
TVGDRRQELVLIGIALDADAWRAKLDACLLTDAEFALGAAGWAAFDDPFPAWDVDSHDDDDHGDTQIVHA

Sequences:

>Translated_470_residues
MRADAAVSPVRGPIAPRQGAAAAFSSLPLVHIIMNPAMKQPLPVTVLSGFLGAGKTTLLNHVLANRAGLKVAVIVNDLAA
VNIDASLVRDAQALSHVEERLVEMSNGCICCTLRDDLLVEIRNLASEGRFDAIMIESTGIAEPMPIAETFTFVDDDGASL
SAIARLDTLVTVVDAYNFLRDYGSDDALATRGIAASEDDDRTLVELLIEQIEFCDVLVINKADLVGADDLARLQHILARL
NPRAHQVVSTFGNVPLDEVLNTGRFDFDEAANAPGWLASLDHDHTHCDDPDCHDDHHAHVHGEADEFGIGNFVYRARRPF
HPARLWALLHQEWPGVLRSKGFFWLATRNDIAGSLSQAGGVCRHGPAGLWWAAQDRAEWPDDDELLAEIRTEWLGDLDDR
TVGDRRQELVLIGIALDADAWRAKLDACLLTDAEFALGAAGWAAFDDPFPAWDVDSHDDDDHGDTQIVHA
>Mature_470_residues
MRADAAVSPVRGPIAPRQGAAAAFSSLPLVHIIMNPAMKQPLPVTVLSGFLGAGKTTLLNHVLANRAGLKVAVIVNDLAA
VNIDASLVRDAQALSHVEERLVEMSNGCICCTLRDDLLVEIRNLASEGRFDAIMIESTGIAEPMPIAETFTFVDDDGASL
SAIARLDTLVTVVDAYNFLRDYGSDDALATRGIAASEDDDRTLVELLIEQIEFCDVLVINKADLVGADDLARLQHILARL
NPRAHQVVSTFGNVPLDEVLNTGRFDFDEAANAPGWLASLDHDHTHCDDPDCHDDHHAHVHGEADEFGIGNFVYRARRPF
HPARLWALLHQEWPGVLRSKGFFWLATRNDIAGSLSQAGGVCRHGPAGLWWAAQDRAEWPDDDELLAEIRTEWLGDLDDR
TVGDRRQELVLIGIALDADAWRAKLDACLLTDAEFALGAAGWAAFDDPFPAWDVDSHDDDDHGDTQIVHA

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI146231952, Length=229, Percent_Identity=33.1877729257642, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI33469141, Length=229, Percent_Identity=32.7510917030568, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI148727351, Length=229, Percent_Identity=32.7510917030568, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI126722884, Length=229, Percent_Identity=32.7510917030568, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI223941779, Length=246, Percent_Identity=31.3008130081301, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI223941776, Length=219, Percent_Identity=31.9634703196347, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI119120938, Length=143, Percent_Identity=38.4615384615385, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI87082430, Length=234, Percent_Identity=32.4786324786325, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1788499, Length=109, Percent_Identity=36.697247706422, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6324356, Length=239, Percent_Identity=28.0334728033473, Blast_Score=94, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 51233; Mature: 51233

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRADAAVSPVRGPIAPRQGAAAAFSSLPLVHIIMNPAMKQPLPVTVLSGFLGAGKTTLLN
CCCCCCCCCCCCCCCCCCCHHHHHHCCCCCEEHHCHHHCCCCCHHHHHHHHCCCHHHHHH
HVLANRAGLKVAVIVNDLAAVNIDASLVRDAQALSHVEERLVEMSNGCICCTLRDDLLVE
HHHHCCCCCEEEEEEECHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHH
IRNLASEGRFDAIMIESTGIAEPMPIAETFTFVDDDGASLSAIARLDTLVTVVDAYNFLR
HHHHHCCCCEEEEEEECCCCCCCCCHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
DYGSDDALATRGIAASEDDDRTLVELLIEQIEFCDVLVINKADLVGADDLARLQHILARL
HCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHC
NPRAHQVVSTFGNVPLDEVLNTGRFDFDEAANAPGWLASLDHDHTHCDDPDCHDDHHAHV
CHHHHHHHHHHCCCCHHHHHCCCCCCCHHHCCCCCCEEECCCCCCCCCCCCCCCCCCEEE
HGEADEFGIGNFVYRARRPFHPARLWALLHQEWPGVLRSKGFFWLATRNDIAGSLSQAGG
CCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCHHHHCCCEEEEEECCCHHHHHHHHCC
VCRHGPAGLWWAAQDRAEWPDDDELLAEIRTEWLGDLDDRTVGDRRQELVLIGIALDADA
CCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCHH
WRAKLDACLLTDAEFALGAAGWAAFDDPFPAWDVDSHDDDDHGDTQIVHA
HHHHHHHHEECCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEC
>Mature Secondary Structure
MRADAAVSPVRGPIAPRQGAAAAFSSLPLVHIIMNPAMKQPLPVTVLSGFLGAGKTTLLN
CCCCCCCCCCCCCCCCCCCHHHHHHCCCCCEEHHCHHHCCCCCHHHHHHHHCCCHHHHHH
HVLANRAGLKVAVIVNDLAAVNIDASLVRDAQALSHVEERLVEMSNGCICCTLRDDLLVE
HHHHCCCCCEEEEEEECHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHH
IRNLASEGRFDAIMIESTGIAEPMPIAETFTFVDDDGASLSAIARLDTLVTVVDAYNFLR
HHHHHCCCCEEEEEEECCCCCCCCCHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
DYGSDDALATRGIAASEDDDRTLVELLIEQIEFCDVLVINKADLVGADDLARLQHILARL
HCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHC
NPRAHQVVSTFGNVPLDEVLNTGRFDFDEAANAPGWLASLDHDHTHCDDPDCHDDHHAHV
CHHHHHHHHHHCCCCHHHHHCCCCCCCHHHCCCCCCEEECCCCCCCCCCCCCCCCCCEEE
HGEADEFGIGNFVYRARRPFHPARLWALLHQEWPGVLRSKGFFWLATRNDIAGSLSQAGG
CCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCHHHHCCCEEEEEECCCHHHHHHHHCC
VCRHGPAGLWWAAQDRAEWPDDDELLAEIRTEWLGDLDDRTVGDRRQELVLIGIALDADA
CCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCHH
WRAKLDACLLTDAEFALGAAGWAAFDDPFPAWDVDSHDDDDHGDTQIVHA
HHHHHHHHEECCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]