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The map label for this gene is cat1 [H]

Identifier: 104779420

GI number: 104779420

Start: 106164

End: 107657

Strand: Reverse

Name: cat1 [H]

Synonym: PSEEN0113

Alternate gene names: 104779420

Gene position: 107657-106164 (Counterclockwise)

Preceding gene: 104779421

Following gene: 104779419

Centisome position: 1.83

GC content: 64.39

Gene sequence:

>1494_bases
ATGTACCGTGATCGTATCCGCTTGTCCTCCCTGCACAGCAAGGTAATGAGTGCGGCTGATGCCGCTGGCCTGATCCAGGA
CGGCATGACCGTCGGCATGAGCGGTTTCACCCGCGCCGGCGAAGCCAAGGCCGTGCCCCACGCACTGGCCGAGCGCGCGA
AACAGTCGCCGCTGAAGATCAGCCTGATGACCGGCGCCAGCCTGGGCAATGACCTGGACAAGCAACTGACCGAAGCCGGC
GTGCTGGCGCGGCGCATGCCGTTCCAGGTCGACAGCACCCTGCGCAAGGCCATTAATGACGGCAAGGTGATGTTCATTGA
CCAGCACCTGTCGGAAACCGTCGAGCAGCTGCGCAACAAACAGCTCACCCTGCCGGATATCGCGGTCATCGAAGCGGTGG
CGATCACCGAACAGGGCCACATCGTGCCGACCACTTCCGTCGGCAACTCGGCCAGCTTCGCGATCTTCGCCAAGCAAGTC
ATCGTCGAGATCAACCTGTCGCACAATGCCAACCTCGAAGGCCTGCACGACATCTATATCCCGACCTACCGCCCGACCCG
CACCCCGATCCCGCTGGTGAAAGTCGACGACCGCATCGGCAGCACCGCCATCCCGATCGACCCGGCCAAGATCGTCGGTA
TCGTCATCAGCGACCAGCCGGACTCGCCGTCCACCGTGCTGCCGCCTGACCACGAGACCCAGGGCATCGCCGACCACCTG
ATCGCCTTCCTCAAAGGCGAAGTGGACGCCGGCCGCATGAGCAACAACCTCGGCCCGCTGCAGGCCGGCATCGGCAGCAT
CGCCAACGCGGTGATGTGCGGCCTGATCGAGTCGCCGTTCGAAAACCTGACCATGTACTCCGAAGTGCTGCAGGACTCGA
CCTTCGACTTGATCGACGCTGGCAAGCTGAGCTTCGCCTCGGGCAGCTCGATCACCCTGTCGAGCCGCCGCAACGCCGAT
GTGTTCGGCAACCTGGAGCGCTACAAGGACAAGCTGGTGCTGCGCCCGCAGGAGATCTCCAACCACCCTGAAGTGGTGCG
TCGCCTGGGGATCATCGGCATCAACACGGCGCTGGAGTTCGACATCTACGGCAACGTCAACTCCACCCACGTCTGTGGCA
CCAAGATGATGAACGGCATCGGTGGCTCGGGTGACTTCGCCCGCAACGCCCACCTGGCGATCTTCGTCACCAAGTCGATC
GCCAAGGGCGGCGCGATTTCCAGCGTGGTGCCGATGGTCAGCCACGTCGACCACACCGAGCATGACGTGGACATCCTGGT
GACCGAGGTGGGCCTGGCCGACCTGCGTGGCCTGGCGCCCCGCGAGCGCGCCCGGGTGATCATCGACAACTGCGTGCACC
CGGACTACCGCGCCGCGCTGAACGACTACTTCGAGCGCGCCTGCCAGCGCGGTGGCCATACGCCGCACATCCTGCGCGAG
GCCTTGAGCTGGCACGAGAATCTGGAAGAGACCGGGCGCATGCTCGTCGGCTGA

Upstream 100 bases:

>100_bases
CTATTTCCGGCCTTCGCCTACGACCATGGTCGCGGGACGGCACCAGGCGAAATCTCTAGACTGCGCTTCCAGTAGCCTCA
GTAGCCCGAGATAACAATCC

Downstream 100 bases:

>100_bases
TGCCCCAACTGTACCGATCGCGGAGCAAGCCGCCTTGCCCCGCGATCCCAGCCCCTCGCCACGCTCCCCGTAGGCGCCAG
CCTTGCTGGCGATGCCCGGC

Product: acetyl-CoA hydrolase/transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MYRDRIRLSSLHSKVMSAADAAGLIQDGMTVGMSGFTRAGEAKAVPHALAERAKQSPLKISLMTGASLGNDLDKQLTEAG
VLARRMPFQVDSTLRKAINDGKVMFIDQHLSETVEQLRNKQLTLPDIAVIEAVAITEQGHIVPTTSVGNSASFAIFAKQV
IVEINLSHNANLEGLHDIYIPTYRPTRTPIPLVKVDDRIGSTAIPIDPAKIVGIVISDQPDSPSTVLPPDHETQGIADHL
IAFLKGEVDAGRMSNNLGPLQAGIGSIANAVMCGLIESPFENLTMYSEVLQDSTFDLIDAGKLSFASGSSITLSSRRNAD
VFGNLERYKDKLVLRPQEISNHPEVVRRLGIIGINTALEFDIYGNVNSTHVCGTKMMNGIGGSGDFARNAHLAIFVTKSI
AKGGAISSVVPMVSHVDHTEHDVDILVTEVGLADLRGLAPRERARVIIDNCVHPDYRAALNDYFERACQRGGHTPHILRE
ALSWHENLEETGRMLVG

Sequences:

>Translated_497_residues
MYRDRIRLSSLHSKVMSAADAAGLIQDGMTVGMSGFTRAGEAKAVPHALAERAKQSPLKISLMTGASLGNDLDKQLTEAG
VLARRMPFQVDSTLRKAINDGKVMFIDQHLSETVEQLRNKQLTLPDIAVIEAVAITEQGHIVPTTSVGNSASFAIFAKQV
IVEINLSHNANLEGLHDIYIPTYRPTRTPIPLVKVDDRIGSTAIPIDPAKIVGIVISDQPDSPSTVLPPDHETQGIADHL
IAFLKGEVDAGRMSNNLGPLQAGIGSIANAVMCGLIESPFENLTMYSEVLQDSTFDLIDAGKLSFASGSSITLSSRRNAD
VFGNLERYKDKLVLRPQEISNHPEVVRRLGIIGINTALEFDIYGNVNSTHVCGTKMMNGIGGSGDFARNAHLAIFVTKSI
AKGGAISSVVPMVSHVDHTEHDVDILVTEVGLADLRGLAPRERARVIIDNCVHPDYRAALNDYFERACQRGGHTPHILRE
ALSWHENLEETGRMLVG
>Mature_497_residues
MYRDRIRLSSLHSKVMSAADAAGLIQDGMTVGMSGFTRAGEAKAVPHALAERAKQSPLKISLMTGASLGNDLDKQLTEAG
VLARRMPFQVDSTLRKAINDGKVMFIDQHLSETVEQLRNKQLTLPDIAVIEAVAITEQGHIVPTTSVGNSASFAIFAKQV
IVEINLSHNANLEGLHDIYIPTYRPTRTPIPLVKVDDRIGSTAIPIDPAKIVGIVISDQPDSPSTVLPPDHETQGIADHL
IAFLKGEVDAGRMSNNLGPLQAGIGSIANAVMCGLIESPFENLTMYSEVLQDSTFDLIDAGKLSFASGSSITLSSRRNAD
VFGNLERYKDKLVLRPQEISNHPEVVRRLGIIGINTALEFDIYGNVNSTHVCGTKMMNGIGGSGDFARNAHLAIFVTKSI
AKGGAISSVVPMVSHVDHTEHDVDILVTEVGLADLRGLAPRERARVIIDNCVHPDYRAALNDYFERACQRGGHTPHILRE
ALSWHENLEETGRMLVG

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=486, Percent_Identity=46.9135802469136, Blast_Score=433, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI17538151, Length=236, Percent_Identity=30.0847457627119, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI32563853, Length=238, Percent_Identity=30.2521008403361, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319456, Length=519, Percent_Identity=44.5086705202312, Blast_Score=427, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 53762; Mature: 53762

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRDRIRLSSLHSKVMSAADAAGLIQDGMTVGMSGFTRAGEAKAVPHALAERAKQSPLKI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEE
SLMTGASLGNDLDKQLTEAGVLARRMPFQVDSTLRKAINDGKVMFIDQHLSETVEQLRNK
EEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCC
QLTLPDIAVIEAVAITEQGHIVPTTSVGNSASFAIFAKQVIVEINLSHNANLEGLHDIYI
CCCCCCHHHHHHEEEECCCCEEEECCCCCCCHHHHEEEEEEEEEECCCCCCCCCCEEEEE
PTYRPTRTPIPLVKVDDRIGSTAIPIDPAKIVGIVISDQPDSPSTVLPPDHETQGIADHL
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHH
IAFLKGEVDAGRMSNNLGPLQAGIGSIANAVMCGLIESPFENLTMYSEVLQDSTFDLIDA
HHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC
GKLSFASGSSITLSSRRNADVFGNLERYKDKLVLRPQEISNHPEVVRRLGIIGINTALEF
CCEEECCCCEEEECCCCCCCHHCCHHHHHHHHEECHHHHCCCHHHHHHHCCEEECCEEEE
DIYGNVNSTHVCGTKMMNGIGGSGDFARNAHLAIFVTKSIAKGGAISSVVPMVSHVDHTE
EEECCCCCCEECHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCC
HDVDILVTEVGLADLRGLAPRERARVIIDNCVHPDYRAALNDYFERACQRGGHTPHILRE
CCCEEEEEHHCHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
ALSWHENLEETGRMLVG
HHHHHHCHHHHCCCCCC
>Mature Secondary Structure
MYRDRIRLSSLHSKVMSAADAAGLIQDGMTVGMSGFTRAGEAKAVPHALAERAKQSPLKI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEE
SLMTGASLGNDLDKQLTEAGVLARRMPFQVDSTLRKAINDGKVMFIDQHLSETVEQLRNK
EEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCC
QLTLPDIAVIEAVAITEQGHIVPTTSVGNSASFAIFAKQVIVEINLSHNANLEGLHDIYI
CCCCCCHHHHHHEEEECCCCEEEECCCCCCCHHHHEEEEEEEEEECCCCCCCCCCEEEEE
PTYRPTRTPIPLVKVDDRIGSTAIPIDPAKIVGIVISDQPDSPSTVLPPDHETQGIADHL
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHH
IAFLKGEVDAGRMSNNLGPLQAGIGSIANAVMCGLIESPFENLTMYSEVLQDSTFDLIDA
HHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC
GKLSFASGSSITLSSRRNADVFGNLERYKDKLVLRPQEISNHPEVVRRLGIIGINTALEF
CCEEECCCCEEEECCCCCCCHHCCHHHHHHHHEECHHHHCCCHHHHHHHCCEEECCEEEE
DIYGNVNSTHVCGTKMMNGIGGSGDFARNAHLAIFVTKSIAKGGAISSVVPMVSHVDHTE
EEECCCCCCEECHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCC
HDVDILVTEVGLADLRGLAPRERARVIIDNCVHPDYRAALNDYFERACQRGGHTPHILRE
CCCEEEEEHHCHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
ALSWHENLEETGRMLVG
HHHHHHCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]