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The map label for this gene is trpB [H]

Identifier: 104779351

GI number: 104779351

Start: 39214

End: 40431

Strand: Reverse

Name: trpB [H]

Synonym: PSEEN0038

Alternate gene names: 104779351

Gene position: 40431-39214 (Counterclockwise)

Preceding gene: 104779353

Following gene: 104779350

Centisome position: 0.69

GC content: 66.5

Gene sequence:

>1218_bases
ATGACCCAGACCCAATACCGCGCCGGCCCCGATGCCAACGGCCTGTTCGGCTCGTTCGGCGGCCGCTACGTGGCCGAAAC
CCTGATGCCCCTGGTGCTGGACCTGGCCCGCGAATACGAAGCCGCCAAGGCCGACCCCAAGTTCCTCGAAGAACTCGCCT
ACTTCCAGCGCGACTACATCGGCCGCCCCAACCCGCTGTACTTCGCCGAGCGCCTGACCGAGCACTGCGGCGGCGCGAAG
ATCTTCTTCAAGCGTGAAGAGCTCAACCACACCGGCGCGCACAAGGTGAACAACTGCATCGGCCAGGTGCTGCTGGCCAA
GCGCATGGGCAAGAAACGCCTGATCGCCGAGACCGGCGCCGGCATGCACGGTGTGGCCACCGCCACCGTCGCCGCGCGCT
TCGGCCTGCCTTGCGTGATCTACATGGGTGCCACCGACATTGAGCGCCAGCAGGCCAACGTGTTCCGCATGAAGCTGCTG
GGCGCCGAGATCGTCCCGGTCACCGCCGGCACCGGCACCCTCAAGGACGCCATGAACGAGGCCCTGCGCGACTGGGTCAC
CAACGTCGAGGACACCTTCTACCTGATCGGCACCGTGGCCGGCCCGCACCCGTACCCGGCGATGGTCCGCGACTTCCAGT
CGATCATCGGCAAGGAAACCCGCGCCCAGCTGCAGGAGAAGGAAGGGCGCCTGCCCGACAGCCTGATCGCCTGCGTCGGC
GGCGGCTCCAATGCCATGGGCCTGTTCCACGACTTCCTCGATGATGCCAGTGTGCAGATCATCGGCGTCGAAGCCGGCGG
TCACGGCGTGCACACCGACAAGCACGCGGCCAGCCTCAACGGCGGCGTGCCGGGCGTACTGCACGGCAACCGCACCTACC
TGCTGCAGGACGACGACGGCCAGATCACCGACGCCCACTCGATCTCGGCAGGCCTGGACTACCCTGGCATCGGCCCGGAG
CACGCCTACCTGCATGAAGTGAAGCGTGTGGAGTACGTCAGCATCACCGACGACGAAGCACTCGACGCCTTCCACGCCAC
CTGCCGCCTGGAAGGCATCATCCCGGCGCTGGAAAGCTCCCACGCCCTGGCCGAGGCGATCAAGCGCGCGCCGAAGCTGC
CCAAGGACCACCTGATGGTGATCTGCCTGTCCGGTCGCGGCGACAAGGACATGCAAACCGTGATGAACCACATGGCCGCC
CAGGAGAAACAGGCATGA

Upstream 100 bases:

>100_bases
GTTTTCCTGACAGGTTTGCGCAATCTTATCGGTTTTCAGCTAGCCGCGTCGTGGTTAGAGTAAAGCCCATCACTCATCCC
ATTACGCCCTGGAGCGCCCC

Downstream 100 bases:

>100_bases
GCCGTCTCGAACAACGCTTCGCCGAATTGAAGGCCGAAGGCCGCTCCGCCCTGGTCACCTTCGTCACCGCCGGCGACCCG
GGCTACGACGCCTCGCTGGA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MTQTQYRAGPDANGLFGSFGGRYVAETLMPLVLDLAREYEAAKADPKFLEELAYFQRDYIGRPNPLYFAERLTEHCGGAK
IFFKREELNHTGAHKVNNCIGQVLLAKRMGKKRLIAETGAGMHGVATATVAARFGLPCVIYMGATDIERQQANVFRMKLL
GAEIVPVTAGTGTLKDAMNEALRDWVTNVEDTFYLIGTVAGPHPYPAMVRDFQSIIGKETRAQLQEKEGRLPDSLIACVG
GGSNAMGLFHDFLDDASVQIIGVEAGGHGVHTDKHAASLNGGVPGVLHGNRTYLLQDDDGQITDAHSISAGLDYPGIGPE
HAYLHEVKRVEYVSITDDEALDAFHATCRLEGIIPALESSHALAEAIKRAPKLPKDHLMVICLSGRGDKDMQTVMNHMAA
QEKQA

Sequences:

>Translated_405_residues
MTQTQYRAGPDANGLFGSFGGRYVAETLMPLVLDLAREYEAAKADPKFLEELAYFQRDYIGRPNPLYFAERLTEHCGGAK
IFFKREELNHTGAHKVNNCIGQVLLAKRMGKKRLIAETGAGMHGVATATVAARFGLPCVIYMGATDIERQQANVFRMKLL
GAEIVPVTAGTGTLKDAMNEALRDWVTNVEDTFYLIGTVAGPHPYPAMVRDFQSIIGKETRAQLQEKEGRLPDSLIACVG
GGSNAMGLFHDFLDDASVQIIGVEAGGHGVHTDKHAASLNGGVPGVLHGNRTYLLQDDDGQITDAHSISAGLDYPGIGPE
HAYLHEVKRVEYVSITDDEALDAFHATCRLEGIIPALESSHALAEAIKRAPKLPKDHLMVICLSGRGDKDMQTVMNHMAA
QEKQA
>Mature_404_residues
TQTQYRAGPDANGLFGSFGGRYVAETLMPLVLDLAREYEAAKADPKFLEELAYFQRDYIGRPNPLYFAERLTEHCGGAKI
FFKREELNHTGAHKVNNCIGQVLLAKRMGKKRLIAETGAGMHGVATATVAARFGLPCVIYMGATDIERQQANVFRMKLLG
AEIVPVTAGTGTLKDAMNEALRDWVTNVEDTFYLIGTVAGPHPYPAMVRDFQSIIGKETRAQLQEKEGRLPDSLIACVGG
GSNAMGLFHDFLDDASVQIIGVEAGGHGVHTDKHAASLNGGVPGVLHGNRTYLLQDDDGQITDAHSISAGLDYPGIGPEH
AYLHEVKRVEYVSITDDEALDAFHATCRLEGIIPALESSHALAEAIKRAPKLPKDHLMVICLSGRGDKDMQTVMNHMAAQ
EKQA

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=390, Percent_Identity=54.6153846153846, Blast_Score=441, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6321412, Length=380, Percent_Identity=56.8421052631579, Blast_Score=459, Evalue=1e-130,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43982; Mature: 43850

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTQYRAGPDANGLFGSFGGRYVAETLMPLVLDLAREYEAAKADPKFLEELAYFQRDYI
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
GRPNPLYFAERLTEHCGGAKIFFKREELNHTGAHKVNNCIGQVLLAKRMGKKRLIAETGA
CCCCHHHHHHHHHHHCCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCC
GMHGVATATVAARFGLPCVIYMGATDIERQQANVFRMKLLGAEIVPVTAGTGTLKDAMNE
CCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHH
ALRDWVTNVEDTFYLIGTVAGPHPYPAMVRDFQSIIGKETRAQLQEKEGRLPDSLIACVG
HHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHEEEEC
GGSNAMGLFHDFLDDASVQIIGVEAGGHGVHTDKHAASLNGGVPGVLHGNRTYLLQDDDG
CCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCEEEECCEEEEEECCCC
QITDAHSISAGLDYPGIGPEHAYLHEVKRVEYVSITDDEALDAFHATCRLEGIIPALESS
CEECCHHCCCCCCCCCCCCCHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHCHHHHHCH
HALAEAIKRAPKLPKDHLMVICLSGRGDKDMQTVMNHMAAQEKQA
HHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQTQYRAGPDANGLFGSFGGRYVAETLMPLVLDLAREYEAAKADPKFLEELAYFQRDYI
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
GRPNPLYFAERLTEHCGGAKIFFKREELNHTGAHKVNNCIGQVLLAKRMGKKRLIAETGA
CCCCHHHHHHHHHHHCCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCC
GMHGVATATVAARFGLPCVIYMGATDIERQQANVFRMKLLGAEIVPVTAGTGTLKDAMNE
CCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHH
ALRDWVTNVEDTFYLIGTVAGPHPYPAMVRDFQSIIGKETRAQLQEKEGRLPDSLIACVG
HHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHEEEEC
GGSNAMGLFHDFLDDASVQIIGVEAGGHGVHTDKHAASLNGGVPGVLHGNRTYLLQDDDG
CCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCEEEECCEEEEEECCCC
QITDAHSISAGLDYPGIGPEHAYLHEVKRVEYVSITDDEALDAFHATCRLEGIIPALESS
CEECCHHCCCCCCCCCCCCCHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHCHHHHHCH
HALAEAIKRAPKLPKDHLMVICLSGRGDKDMQTVMNHMAAQEKQA
HHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA