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The map label for this gene is pnuC [H]

Identifier: 103488606

GI number: 103488606

Start: 3283344

End: 3283913

Strand: Reverse

Name: pnuC [H]

Synonym: Sala_3131

Alternate gene names: 103488606

Gene position: 3283913-3283344 (Counterclockwise)

Preceding gene: 103488607

Following gene: 103488605

Centisome position: 98.17

GC content: 68.25

Gene sequence:

>570_bases
ATGAACCCCGTCGAATGGGTTGCCGCCGCCTTCGTGCTCACCAATGTCGCGCTCGTCGCGCTGCGCAGCGTCTGGAACTA
TCCCTTCGCGCTCGTCGCGGTGGCGCTCTATGCCTTCGTCTTCTTCGAGGCGAAGCTGTACAGCGACATGCTGCTCCAGG
GCTTTTTCTTCGCGCTCAATCTTTATGGCTGGGCGGCGTGGACGCGCGCACGGACCGACAGCGGCGTCCCGGTCGGCTGG
ATGGGCGACCGCGCGCGATGGGGCTGGGGGCTCGGCACGCTAGCCGCCTGGGCGGGATGGAGCTATGCGATGGACCGCCA
CACCGACGCGGCGGCGCCATGGATCGACGGCGCGATCGCGATGATCAGCGTCACCGCGCAATGGCTGCTCGCGCGGCGGC
GCGTCGAAAGCTGGTATCTGTGGATCCTCGTCGACCTGATCGCGATCCCGCTCTTCGCATCGCGCGGGCTTTACGCGACC
AGCGCGGTCTATGTCGTGCTGCTCGGCCTGTCGATCGACGGGCTGATCCAGTGGCGCCGCGCGGCGGCGACCGGGCGGCT
CGCGCCATGA

Upstream 100 bases:

>100_bases
CGGTGCTCCGCCGCCCGCCAGAGCGACGGATCAGCCGCGAGGGGCTGTGGACGCGGCCCCGGCCGGACGGCGTACACACG
CACGGGGAGTGCGCAGGCGC

Downstream 100 bases:

>100_bases
CCCGGCACATCTGCCTGCACGGCGCCGAAAGCACGGGCAAGTCGACGCTCGCCCCGCGGCTCGCGCTGCGGCTCGGCGGG
CTGGTCGTCCCCGAATATGG

Product: nicotinamide mononucleotide transporter

Products: nicotinamide nucleotide [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MNPVEWVAAAFVLTNVALVALRSVWNYPFALVAVALYAFVFFEAKLYSDMLLQGFFFALNLYGWAAWTRARTDSGVPVGW
MGDRARWGWGLGTLAAWAGWSYAMDRHTDAAAPWIDGAIAMISVTAQWLLARRRVESWYLWILVDLIAIPLFASRGLYAT
SAVYVVLLGLSIDGLIQWRRAAATGRLAP

Sequences:

>Translated_189_residues
MNPVEWVAAAFVLTNVALVALRSVWNYPFALVAVALYAFVFFEAKLYSDMLLQGFFFALNLYGWAAWTRARTDSGVPVGW
MGDRARWGWGLGTLAAWAGWSYAMDRHTDAAAPWIDGAIAMISVTAQWLLARRRVESWYLWILVDLIAIPLFASRGLYAT
SAVYVVLLGLSIDGLIQWRRAAATGRLAP
>Mature_189_residues
MNPVEWVAAAFVLTNVALVALRSVWNYPFALVAVALYAFVFFEAKLYSDMLLQGFFFALNLYGWAAWTRARTDSGVPVGW
MGDRARWGWGLGTLAAWAGWSYAMDRHTDAAAPWIDGAIAMISVTAQWLLARRRVESWYLWILVDLIAIPLFASRGLYAT
SAVYVVLLGLSIDGLIQWRRAAATGRLAP

Specific function: Required for nicotinamide riboside transport across the inner membrane [H]

COG id: COG3201

COG function: function code H; Nicotinamide mononucleotide transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786965, Length=205, Percent_Identity=28.2926829268293, Blast_Score=90, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006419 [H]

Pfam domain/function: PF04973 NMN_transporter [H]

EC number: NA

Molecular weight: Translated: 21053; Mature: 21053

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPVEWVAAAFVLTNVALVALRSVWNYPFALVAVALYAFVFFEAKLYSDMLLQGFFFALN
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYGWAAWTRARTDSGVPVGWMGDRARWGWGLGTLAAWAGWSYAMDRHTDAAAPWIDGAIA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHCCCCCCCCHHHHHHH
MISVTAQWLLARRRVESWYLWILVDLIAIPLFASRGLYATSAVYVVLLGLSIDGLIQWRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHH
AAATGRLAP
HHCCCCCCC
>Mature Secondary Structure
MNPVEWVAAAFVLTNVALVALRSVWNYPFALVAVALYAFVFFEAKLYSDMLLQGFFFALN
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYGWAAWTRARTDSGVPVGWMGDRARWGWGLGTLAAWAGWSYAMDRHTDAAAPWIDGAIA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHCCCCCCCCHHHHHHH
MISVTAQWLLARRRVESWYLWILVDLIAIPLFASRGLYATSAVYVVLLGLSIDGLIQWRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHH
AAATGRLAP
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nicotinamide nucleotide [Periplasm] [C]

Specific reaction: nicotinamide nucleotide [Periplasm] = nicotinamide nucleotide [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 2841129; 2198247 [H]