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The map label for this gene is emrK [H]

Identifier: 103488591

GI number: 103488591

Start: 3264792

End: 3265931

Strand: Direct

Name: emrK [H]

Synonym: Sala_3115

Alternate gene names: 103488591

Gene position: 3264792-3265931 (Clockwise)

Preceding gene: 103488590

Following gene: 103488592

Centisome position: 97.6

GC content: 70.44

Gene sequence:

>1140_bases
ATGATGGCCGATGAAACGGCGGCTGCCGACATCGACGCGCTGGAAACATATGGCGCGAAACGCCGGAAGCTGCTCCGCAT
CCTTGCGCTCGTCGTGCTGGCCGCCGCGATCCTGTGGGGCGCCTGGTATTTTCTGACGCAGGCGGGGCGCGTTCACACCG
ACAACGCCTATGTCGGCGCCGATTCGGCGCAGGTGACCGCGCTCGTTTCGGGTCCGGTGAAGGACGTGCGCGTCAGCGGG
ACGCAGGCGGTGAAGCGGGGCGACATTCTGGTCATCCTCGACGATGCCGACCAGCGCATCGCGCTTGCCGACGCCGAGGC
GGCGCTGCGCCTTGCGCGCCAGCGTTACGGGCAGGCCGATGCGAATGCCGATGCGGCGCGCGCGCGTGTTGCCGCCCGCG
GCGCCGATGTCGCGCAGGCGCGCGCCCGGCTGCGCGATGCCGAGGCGAGCGTCGAACGCGCGCGCGCCGAACTGGCGCGG
CGCGAGAGCATCGCAGGCACCGGCGCGGTGTCGGCCGAGGAGCTGACCGCGGCGCGTGCAGCGGTCAAGCAGGCGCACGC
CGCGCGCGACCTTGCCGCCGCGGCGATCGCCGCGGCCGAGGCAACGCGCGGATCGGCAAGCGGCGACCTTGGCGCCGCCG
AGGCGGTGGTGCGCGGGACGACGGTGGACACTGCCCCTGAAGTGGCGGCGGCGGCGGCGCGCGTCGAAAAGGCGCGGCTC
GATCTCGCGCGCACGGTGATCCGCGCGCCGGTCGATGGCATTGTCACCAACCGGCAGGTGCAGGTCGGCCAGCGGATCGC
CGCGGGCGCGCCGATCATGGTGATCGTTCCCATCGCGACCGCCTATGTCGATGCCAATTTCAAGGAAAGCCAGTTCGAGG
ATATCCGCATCGGCCAGCCGGTCGAACTGACCTCGGACTATTATGGCGGCGATGTCGTCTATCGCGGCAAGGTGGTCGGC
ATCGCCGGCGGCACCGGCGCGGCCTTTTCGCTGATCCCCGCGCAGAATGCGACGGGCAACTGGGTGAAGGTCGTCCAGCG
GCTGCCGGTGCGCATCGCGCTCGATCCGAAGCAGCTGAAAGAACATCCGCTGCGCGTCGGGCTGTCGATGGAAGCGACGA
TCGACACGCGCGGCAACTGA

Upstream 100 bases:

>100_bases
GCGCCGTGACCGATCTCGAAGCGCGCCAGCTGGCGCTCGACATCGCGCTGATCCGGGCGCTCGGCGGCGGATACCAGGCG
CCCGACCCGACAGGAGACGA

Downstream 100 bases:

>100_bases
GATGCGCGTCCATCATCTCTCCTCTTCGTCATTGCGAGCGAAGCGAAGCAATCTCCAGCTAACGATCTGGATGGGCGCTC
GCAGGAGATTGCCGCGTCGC

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MMADETAAADIDALETYGAKRRKLLRILALVVLAAAILWGAWYFLTQAGRVHTDNAYVGADSAQVTALVSGPVKDVRVSG
TQAVKRGDILVILDDADQRIALADAEAALRLARQRYGQADANADAARARVAARGADVAQARARLRDAEASVERARAELAR
RESIAGTGAVSAEELTAARAAVKQAHAARDLAAAAIAAAEATRGSASGDLGAAEAVVRGTTVDTAPEVAAAAARVEKARL
DLARTVIRAPVDGIVTNRQVQVGQRIAAGAPIMVIVPIATAYVDANFKESQFEDIRIGQPVELTSDYYGGDVVYRGKVVG
IAGGTGAAFSLIPAQNATGNWVKVVQRLPVRIALDPKQLKEHPLRVGLSMEATIDTRGN

Sequences:

>Translated_379_residues
MMADETAAADIDALETYGAKRRKLLRILALVVLAAAILWGAWYFLTQAGRVHTDNAYVGADSAQVTALVSGPVKDVRVSG
TQAVKRGDILVILDDADQRIALADAEAALRLARQRYGQADANADAARARVAARGADVAQARARLRDAEASVERARAELAR
RESIAGTGAVSAEELTAARAAVKQAHAARDLAAAAIAAAEATRGSASGDLGAAEAVVRGTTVDTAPEVAAAAARVEKARL
DLARTVIRAPVDGIVTNRQVQVGQRIAAGAPIMVIVPIATAYVDANFKESQFEDIRIGQPVELTSDYYGGDVVYRGKVVG
IAGGTGAAFSLIPAQNATGNWVKVVQRLPVRIALDPKQLKEHPLRVGLSMEATIDTRGN
>Mature_379_residues
MMADETAAADIDALETYGAKRRKLLRILALVVLAAAILWGAWYFLTQAGRVHTDNAYVGADSAQVTALVSGPVKDVRVSG
TQAVKRGDILVILDDADQRIALADAEAALRLARQRYGQADANADAARARVAARGADVAQARARLRDAEASVERARAELAR
RESIAGTGAVSAEELTAARAAVKQAHAARDLAAAAIAAAEATRGSASGDLGAAEAVVRGTTVDTAPEVAAAAARVEKARL
DLARTVIRAPVDGIVTNRQVQVGQRIAAGAPIMVIVPIATAYVDANFKESQFEDIRIGQPVELTSDYYGGDVVYRGKVVG
IAGGTGAAFSLIPAQNATGNWVKVVQRLPVRIALDPKQLKEHPLRVGLSMEATIDTRGN

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=361, Percent_Identity=39.8891966759003, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1789041, Length=357, Percent_Identity=40.8963585434174, Blast_Score=244, Evalue=8e-66,
Organism=Escherichia coli, GI1790519, Length=334, Percent_Identity=32.0359281437126, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1789637, Length=341, Percent_Identity=29.0322580645161, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081951, Length=341, Percent_Identity=26.099706744868, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39637; Mature: 39637

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMADETAAADIDALETYGAKRRKLLRILALVVLAAAILWGAWYFLTQAGRVHTDNAYVGA
CCCCCHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEECC
DSAQVTALVSGPVKDVRVSGTQAVKRGDILVILDDADQRIALADAEAALRLARQRYGQAD
CCCEEEEEECCCCHHEEECCHHHHCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHCCCCC
ANADAARARVAARGADVAQARARLRDAEASVERARAELARRESIAGTGAVSAEELTAARA
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
AVKQAHAARDLAAAAIAAAEATRGSASGDLGAAEAVVRGTTVDTAPEVAAAAARVEKARL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
DLARTVIRAPVDGIVTNRQVQVGQRIAAGAPIMVIVPIATAYVDANFKESQFEDIRIGQP
HHHHHHHHCCCCHHHCCCHHHHHHHHHCCCCEEEEEEHHHHHCCCCCCCCCCCCCCCCCC
VELTSDYYGGDVVYRGKVVGIAGGTGAAFSLIPAQNATGNWVKVVQRLPVRIALDPKQLK
CEECCCCCCCEEEEECEEEEEECCCCCEEEEEECCCCCCHHHHHHHHCCCEEEECHHHHH
EHPLRVGLSMEATIDTRGN
CCCCEECCEEEEEECCCCC
>Mature Secondary Structure
MMADETAAADIDALETYGAKRRKLLRILALVVLAAAILWGAWYFLTQAGRVHTDNAYVGA
CCCCCHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEECC
DSAQVTALVSGPVKDVRVSGTQAVKRGDILVILDDADQRIALADAEAALRLARQRYGQAD
CCCEEEEEECCCCHHEEECCHHHHCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHCCCCC
ANADAARARVAARGADVAQARARLRDAEASVERARAELARRESIAGTGAVSAEELTAARA
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
AVKQAHAARDLAAAAIAAAEATRGSASGDLGAAEAVVRGTTVDTAPEVAAAAARVEKARL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
DLARTVIRAPVDGIVTNRQVQVGQRIAAGAPIMVIVPIATAYVDANFKESQFEDIRIGQP
HHHHHHHHCCCCHHHCCCHHHHHHHHHCCCCEEEEEEHHHHHCCCCCCCCCCCCCCCCCC
VELTSDYYGGDVVYRGKVVGIAGGTGAAFSLIPAQNATGNWVKVVQRLPVRIALDPKQLK
CEECCCCCCCEEEEECEEEEEECCCCCEEEEEECCCCCCHHHHHHHHCCCEEEECHHHHH
EHPLRVGLSMEATIDTRGN
CCCCEECCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]