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The map label for this gene is crt [H]

Identifier: 103488530

GI number: 103488530

Start: 3204523

End: 3205581

Strand: Direct

Name: crt [H]

Synonym: Sala_3054

Alternate gene names: 103488530

Gene position: 3204523-3205581 (Clockwise)

Preceding gene: 103488529

Following gene: 103488531

Centisome position: 95.8

GC content: 63.83

Gene sequence:

>1059_bases
TTGAGAGGTTTTATGATCGAAGACGTTCTTATCTCGACCGACGGCCGCATCGGACGCATCGCGCTCAACCGCCCCAAGGC
GATCCATGCGCTCAACCTCGCAATGTGTCAGGCGATGATCGATGCGCTTTTGAAATGGCGTGCTGACGATGGCATCGAAG
CGGTGACCATCGAGCATAGCGAAGGCCGCGGCTTCTGCGCCGGCGGCGACATCCGTATGCTCGCGGAAAGTGGTGCGAAG
GACGGGGTCGAAGCGCGCCAATTCTTCCACACCGAATATCGCCTCAACCATCTGCTCTTCACCTATCCCAAGCCTGTCGT
TGCCTTCATGGACGGCATCACCATGGGCGGCGGCGTCGGCATTTCGCAGCCGGCCAAATATCGCGTCGCGACCGAACATA
CCCGTTTTGCGATGCCTGAAACGGGGATCGGCCTGTTCCCCGACGTCGGCGGCGGCTGGTATCTGCCGCGGCTCGAGGGG
CGCGTCGGCGTGTTCCTCGCGCTTACCGGCGCGCGGCTCGACGGGGCGGAGTGCCTCGCGCTCGGCCTCGCGACCCATTA
TCTGCCGTCCGAAAAGCTTGCCGAGGCGAAGGCGCGCATCGCCGCGCACCCCGACCGCATCGGCGGCATATTGGGCGAGC
TGTCGGTCGCCGCACCGCCCGCCGCGATCACCCGGCATATCGACAGGATCAACCGGCTGTTCGCCAGCGACCGCTACGAG
GACATTCTCGCCGCGCTCGAAGCCGATGGCGGCGAATGGGCCGAAAAGGAACTGGCCGCGCTACACAGCAAATCGCCGCA
GACATGCAAGGTCGCGCTGCGCCAGCTCAAGGAGGGGGCGGTGATGCACGACTTCGCCGCAGAGATGGCGCAGGAATATG
CGATCGGCAGCCGCGTCGTTCAGATGCACGACTTCATCGAAGGCGTCCGCGCGCTGATAATCGACAAGGACAACAGCCCG
AAATGGAACCCGCCGACGCCGGAGGGCGTGACCGACGACTGGATCGACGCGATATTCGCGCCGCTGCCCGAAAACGAGAC
ATGGACCCCTCTAACTTGA

Upstream 100 bases:

>100_bases
AGGGGCGGTGCGCTATCGGTACGGCGGATTCCCTCATCCAACTCCGCCTAACCGCCGAAGGCGGTAAGGCTCCATATCCT
TCTCCCAATGGGAGAAGGTT

Downstream 100 bases:

>100_bases
ACCGTCACCCCGGCGAAGGCCGGGGTTCACCGTCGAGATTCCGGCCTTCGCCGGAATGACGAAGGAGATTGCCAAATGAC
CTACGAAACCCTCCTCGTCG

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MRGFMIEDVLISTDGRIGRIALNRPKAIHALNLAMCQAMIDALLKWRADDGIEAVTIEHSEGRGFCAGGDIRMLAESGAK
DGVEARQFFHTEYRLNHLLFTYPKPVVAFMDGITMGGGVGISQPAKYRVATEHTRFAMPETGIGLFPDVGGGWYLPRLEG
RVGVFLALTGARLDGAECLALGLATHYLPSEKLAEAKARIAAHPDRIGGILGELSVAAPPAAITRHIDRINRLFASDRYE
DILAALEADGGEWAEKELAALHSKSPQTCKVALRQLKEGAVMHDFAAEMAQEYAIGSRVVQMHDFIEGVRALIIDKDNSP
KWNPPTPEGVTDDWIDAIFAPLPENETWTPLT

Sequences:

>Translated_352_residues
MRGFMIEDVLISTDGRIGRIALNRPKAIHALNLAMCQAMIDALLKWRADDGIEAVTIEHSEGRGFCAGGDIRMLAESGAK
DGVEARQFFHTEYRLNHLLFTYPKPVVAFMDGITMGGGVGISQPAKYRVATEHTRFAMPETGIGLFPDVGGGWYLPRLEG
RVGVFLALTGARLDGAECLALGLATHYLPSEKLAEAKARIAAHPDRIGGILGELSVAAPPAAITRHIDRINRLFASDRYE
DILAALEADGGEWAEKELAALHSKSPQTCKVALRQLKEGAVMHDFAAEMAQEYAIGSRVVQMHDFIEGVRALIIDKDNSP
KWNPPTPEGVTDDWIDAIFAPLPENETWTPLT
>Mature_352_residues
MRGFMIEDVLISTDGRIGRIALNRPKAIHALNLAMCQAMIDALLKWRADDGIEAVTIEHSEGRGFCAGGDIRMLAESGAK
DGVEARQFFHTEYRLNHLLFTYPKPVVAFMDGITMGGGVGISQPAKYRVATEHTRFAMPETGIGLFPDVGGGWYLPRLEG
RVGVFLALTGARLDGAECLALGLATHYLPSEKLAEAKARIAAHPDRIGGILGELSVAAPPAAITRHIDRINRLFASDRYE
DILAALEADGGEWAEKELAALHSKSPQTCKVALRQLKEGAVMHDFAAEMAQEYAIGSRVVQMHDFIEGVRALIIDKDNSP
KWNPPTPEGVTDDWIDAIFAPLPENETWTPLT

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=345, Percent_Identity=41.4492753623188, Blast_Score=268, Evalue=6e-72,
Organism=Homo sapiens, GI37594469, Length=283, Percent_Identity=42.4028268551237, Blast_Score=227, Evalue=1e-59,
Organism=Homo sapiens, GI194097323, Length=248, Percent_Identity=28.6290322580645, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI31542718, Length=188, Percent_Identity=29.2553191489362, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI68989263, Length=174, Percent_Identity=29.8850574712644, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1787660, Length=204, Percent_Identity=30.3921568627451, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787659, Length=202, Percent_Identity=28.2178217821782, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI221142681, Length=200, Percent_Identity=28, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788597, Length=193, Percent_Identity=27.979274611399, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788682, Length=168, Percent_Identity=29.7619047619048, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790281, Length=184, Percent_Identity=25.5434782608696, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25144160, Length=348, Percent_Identity=40.8045977011494, Blast_Score=274, Evalue=7e-74,
Organism=Caenorhabditis elegans, GI25144157, Length=348, Percent_Identity=40.8045977011494, Blast_Score=273, Evalue=8e-74,
Organism=Caenorhabditis elegans, GI25145438, Length=248, Percent_Identity=27.8225806451613, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17554946, Length=191, Percent_Identity=28.7958115183246, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI25144276, Length=170, Percent_Identity=30, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508951, Length=170, Percent_Identity=30, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17508953, Length=170, Percent_Identity=30, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17558304, Length=183, Percent_Identity=26.775956284153, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560910, Length=198, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=388, Percent_Identity=31.701030927835, Blast_Score=175, Evalue=8e-45,
Organism=Drosophila melanogaster, GI28571729, Length=341, Percent_Identity=42.8152492668622, Blast_Score=271, Evalue=3e-73,
Organism=Drosophila melanogaster, GI28571730, Length=341, Percent_Identity=42.8152492668622, Blast_Score=271, Evalue=4e-73,
Organism=Drosophila melanogaster, GI20129971, Length=244, Percent_Identity=26.6393442622951, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24653477, Length=244, Percent_Identity=26.6393442622951, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24653139, Length=181, Percent_Identity=29.8342541436464, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 38378; Mature: 38378

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGFMIEDVLISTDGRIGRIALNRPKAIHALNLAMCQAMIDALLKWRADDGIEAVTIEHS
CCCEEEEHEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
EGRGFCAGGDIRMLAESGAKDGVEARQFFHTEYRLNHLLFTYPKPVVAFMDGITMGGGVG
CCCEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHEEEECCCHHHHHHCCCCCCCCCC
ISQPAKYRVATEHTRFAMPETGIGLFPDVGGGWYLPRLEGRVGVFLALTGARLDGAECLA
CCCCCCEEEEECCCEECCCCCCCCCCCCCCCCEECCEECCCEEEEEEEECCCCCCHHHHH
LGLATHYLPSEKLAEAKARIAAHPDRIGGILGELSVAAPPAAITRHIDRINRLFASDRYE
HHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHH
DILAALEADGGEWAEKELAALHSKSPQTCKVALRQLKEGAVMHDFAAEMAQEYAIGSRVV
HHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
QMHDFIEGVRALIIDKDNSPKWNPPTPEGVTDDWIDAIFAPLPENETWTPLT
HHHHHHHHHHEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MRGFMIEDVLISTDGRIGRIALNRPKAIHALNLAMCQAMIDALLKWRADDGIEAVTIEHS
CCCEEEEHEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
EGRGFCAGGDIRMLAESGAKDGVEARQFFHTEYRLNHLLFTYPKPVVAFMDGITMGGGVG
CCCEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHEEEECCCHHHHHHCCCCCCCCCC
ISQPAKYRVATEHTRFAMPETGIGLFPDVGGGWYLPRLEGRVGVFLALTGARLDGAECLA
CCCCCCEEEEECCCEECCCCCCCCCCCCCCCCEECCEECCCEEEEEEEECCCCCCHHHHH
LGLATHYLPSEKLAEAKARIAAHPDRIGGILGELSVAAPPAAITRHIDRINRLFASDRYE
HHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHH
DILAALEADGGEWAEKELAALHSKSPQTCKVALRQLKEGAVMHDFAAEMAQEYAIGSRVV
HHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
QMHDFIEGVRALIIDKDNSPKWNPPTPEGVTDDWIDAIFAPLPENETWTPLT
HHHHHHHHHHEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]