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The map label for this gene is exuT [H]

Identifier: 103488521

GI number: 103488521

Start: 3195281

End: 3196588

Strand: Direct

Name: exuT [H]

Synonym: Sala_3045

Alternate gene names: 103488521

Gene position: 3195281-3196588 (Clockwise)

Preceding gene: 103488520

Following gene: 103488522

Centisome position: 95.52

GC content: 62.84

Gene sequence:

>1308_bases
ATGGCACAGGCAATCGCAGACAGGGGTGCGGCGGTGCCGGTGCCCCGTTCGGGCCGCTACCGCTGGCTGATCGTCGCGGT
GCTCTTCGCCGCGACCACCGTCAACTATATCGACCGCACCATGCTCGGCCTGCTCGCGCCGACGCTTGGGCAGGAGCTGG
GGTGGAGCGAGAATGACTATGGCAACATCGTCACCGCATTCCAGGCGGCCTATGCACTCGGCTTTCTGTTCATGGGCTGG
CTGATCGACCGCTTCGGACCCAAGATCGGCTATGCGATCGCGATCGGCATCTGGACGGTCGGCCATGTCGCGCACGGCTT
TGCGTCGTCGGTCGTCTCCTTCATGCTTGCGCGCGTCATACTGGGCGTCGGCGAAGCGGGGCATTTTCCCTCGGTCGTCC
GCGCGTCGAGCGAATGGTTCCCGCAAAAGGAACGCTCCTATGCGATCGGCTGGGTCAATAGCGCGACGACGATCGGCGTC
ATCCTGACCGCGCCGACCGTCGCGCTCTTCATGCGCGTGCTCGGCTTCGATTGGCGTGAAACCTTCATCTATACCGGCAT
TTTCGGCGTCGTCCTGCTGCTGCTCTGGCTCTGGCTCTACAGCAACCCGCGCGAAAGCGGGAAGGTCAGCGAGGCCGAAC
TGGCGTGGATCGAGCATGACCCGCCCGAACAGGTCGAACGCATCGGCTGGAGCCGGATCGTCACCAAGCGCGAAGCCTGG
GCCTTTGCGATGGCCAAGTTTCTGACCGACCCGGTGTGGTTCCTGATGCTCTTCTGGCTGCCCAAATATTTCAGCTCGAC
TTATGATGTGGACCTCAAGATCGTGCTGCTGCCGATGATCATCATGTATCTGCTCTCCGATGTCGGCAGCATCCTCGGCG
GCTGGGTGTCGTCGAAGCTGATCCAGACCGGCCACAGCGTCAATTTTGCGCGCAAGGTGACGATGATCGGCGCGGGCCTT
TGCGTATTGCCGCTCTTGTTCGTGACGGGGCTCGAAAATATGTGGCTCGCGGTCGTGCTGATCGGCATCGCGCTCGCGGG
GCATCAGGCCTTTTCCTCGACGATCCTGTCGATCCCGCCCGACATGTTTCCGAAACGCGCGGTCGGATCGGTAATCGGGC
TCGGCGGTTTCATGGGCGGCGTCGGCGGCATGATCATGGCGAAGTCGACGGGGCTTGTGCTCGATGCGACGGGGGGCAAT
TACACCCTCATCTTCGCCGCCTGCACCACCGTCTATTTCCTCGCGGTGCTCGCGGTGCATATCCTCAGCCCGCGCCTCGC
GCCGGTCAGCGTCGAAGGCGCGAAATAG

Upstream 100 bases:

>100_bases
GAGGTCCGGCCCGGCCAGCGGGCCGAAGCGCTGTTCGACGGAAAGATCCGCGTCGGCTGCACGATCACAAGTTATTAGAA
GCGCAACACGGGAGAGGATG

Downstream 100 bases:

>100_bases
GCCCGTGCCGCGTCCGCTGTACCTGTCACCCGACCGCCTCTTCCCGTCCGACCCGGCGCAGCGCGACATCGCGCGCCGGC
TGTATAAGGCGGTCGCAGGT

Product: major facilitator transporter

Products: galacturonate [Cytoplasm]; Proton [Cytoplasm]; glucuronate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MAQAIADRGAAVPVPRSGRYRWLIVAVLFAATTVNYIDRTMLGLLAPTLGQELGWSENDYGNIVTAFQAAYALGFLFMGW
LIDRFGPKIGYAIAIGIWTVGHVAHGFASSVVSFMLARVILGVGEAGHFPSVVRASSEWFPQKERSYAIGWVNSATTIGV
ILTAPTVALFMRVLGFDWRETFIYTGIFGVVLLLLWLWLYSNPRESGKVSEAELAWIEHDPPEQVERIGWSRIVTKREAW
AFAMAKFLTDPVWFLMLFWLPKYFSSTYDVDLKIVLLPMIIMYLLSDVGSILGGWVSSKLIQTGHSVNFARKVTMIGAGL
CVLPLLFVTGLENMWLAVVLIGIALAGHQAFSSTILSIPPDMFPKRAVGSVIGLGGFMGGVGGMIMAKSTGLVLDATGGN
YTLIFAACTTVYFLAVLAVHILSPRLAPVSVEGAK

Sequences:

>Translated_435_residues
MAQAIADRGAAVPVPRSGRYRWLIVAVLFAATTVNYIDRTMLGLLAPTLGQELGWSENDYGNIVTAFQAAYALGFLFMGW
LIDRFGPKIGYAIAIGIWTVGHVAHGFASSVVSFMLARVILGVGEAGHFPSVVRASSEWFPQKERSYAIGWVNSATTIGV
ILTAPTVALFMRVLGFDWRETFIYTGIFGVVLLLLWLWLYSNPRESGKVSEAELAWIEHDPPEQVERIGWSRIVTKREAW
AFAMAKFLTDPVWFLMLFWLPKYFSSTYDVDLKIVLLPMIIMYLLSDVGSILGGWVSSKLIQTGHSVNFARKVTMIGAGL
CVLPLLFVTGLENMWLAVVLIGIALAGHQAFSSTILSIPPDMFPKRAVGSVIGLGGFMGGVGGMIMAKSTGLVLDATGGN
YTLIFAACTTVYFLAVLAVHILSPRLAPVSVEGAK
>Mature_434_residues
AQAIADRGAAVPVPRSGRYRWLIVAVLFAATTVNYIDRTMLGLLAPTLGQELGWSENDYGNIVTAFQAAYALGFLFMGWL
IDRFGPKIGYAIAIGIWTVGHVAHGFASSVVSFMLARVILGVGEAGHFPSVVRASSEWFPQKERSYAIGWVNSATTIGVI
LTAPTVALFMRVLGFDWRETFIYTGIFGVVLLLLWLWLYSNPRESGKVSEAELAWIEHDPPEQVERIGWSRIVTKREAWA
FAMAKFLTDPVWFLMLFWLPKYFSSTYDVDLKIVLLPMIIMYLLSDVGSILGGWVSSKLIQTGHSVNFARKVTMIGAGLC
VLPLLFVTGLENMWLAVVLIGIALAGHQAFSSTILSIPPDMFPKRAVGSVIGLGGFMGGVGGMIMAKSTGLVLDATGGNY
TLIFAACTTVYFLAVLAVHILSPRLAPVSVEGAK

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=377, Percent_Identity=23.0769230769231, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI6912666, Length=443, Percent_Identity=23.0248306997743, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI21322234, Length=291, Percent_Identity=24.3986254295533, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI9966811, Length=292, Percent_Identity=23.2876712328767, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI9945322, Length=292, Percent_Identity=23.972602739726, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI2367193, Length=409, Percent_Identity=30.0733496332518, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI2367379, Length=424, Percent_Identity=29.7169811320755, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI87082320, Length=407, Percent_Identity=27.5184275184275, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1789515, Length=412, Percent_Identity=28.1553398058252, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789152, Length=445, Percent_Identity=25.1685393258427, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI87082071, Length=381, Percent_Identity=21.259842519685, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87082404, Length=354, Percent_Identity=24.5762711864407, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87082231, Length=195, Percent_Identity=24.1025641025641, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17535049, Length=416, Percent_Identity=23.0769230769231, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71991453, Length=418, Percent_Identity=22.488038277512, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71991448, Length=418, Percent_Identity=22.488038277512, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17569727, Length=323, Percent_Identity=24.4582043343653, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560030, Length=357, Percent_Identity=22.4089635854342, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI86561091, Length=248, Percent_Identity=25.4032258064516, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17552542, Length=355, Percent_Identity=23.943661971831, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25141318, Length=248, Percent_Identity=25.4032258064516, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25141316, Length=248, Percent_Identity=25.4032258064516, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19920686, Length=413, Percent_Identity=23.0024213075061, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24583789, Length=369, Percent_Identity=26.0162601626016, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24639764, Length=422, Percent_Identity=23.2227488151659, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641682, Length=386, Percent_Identity=20.9844559585492, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24584153, Length=377, Percent_Identity=23.342175066313, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47370; Mature: 47239

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQAIADRGAAVPVPRSGRYRWLIVAVLFAATTVNYIDRTMLGLLAPTLGQELGWSENDY
CCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GNIVTAFQAAYALGFLFMGWLIDRFGPKIGYAIAIGIWTVGHVAHGFASSVVSFMLARVI
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVGEAGHFPSVVRASSEWFPQKERSYAIGWVNSATTIGVILTAPTVALFMRVLGFDWRE
HHCCCCCCCHHHHHCCHHCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHCCCHHH
TFIYTGIFGVVLLLLWLWLYSNPRESGKVSEAELAWIEHDPPEQVERIGWSRIVTKREAW
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEECCCCHHHHHHCCHHHHHHHHHHH
AFAMAKFLTDPVWFLMLFWLPKYFSSTYDVDLKIVLLPMIIMYLLSDVGSILGGWVSSKL
HHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQTGHSVNFARKVTMIGAGLCVLPLLFVTGLENMWLAVVLIGIALAGHQAFSSTILSIPP
HHCCCCCHHHHHHHHHHCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DMFPKRAVGSVIGLGGFMGGVGGMIMAKSTGLVLDATGGNYTLIFAACTTVYFLAVLAVH
CCCCHHHHHHHHHHHHHHHHHCCEEEEECCCEEEECCCCCEEEHHHHHHHHHHHHHHHHH
ILSPRLAPVSVEGAK
HHCCCCCCCCCCCCC
>Mature Secondary Structure 
AQAIADRGAAVPVPRSGRYRWLIVAVLFAATTVNYIDRTMLGLLAPTLGQELGWSENDY
CCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GNIVTAFQAAYALGFLFMGWLIDRFGPKIGYAIAIGIWTVGHVAHGFASSVVSFMLARVI
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVGEAGHFPSVVRASSEWFPQKERSYAIGWVNSATTIGVILTAPTVALFMRVLGFDWRE
HHCCCCCCCHHHHHCCHHCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHCCCHHH
TFIYTGIFGVVLLLLWLWLYSNPRESGKVSEAELAWIEHDPPEQVERIGWSRIVTKREAW
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEECCCCHHHHHHCCHHHHHHHHHHH
AFAMAKFLTDPVWFLMLFWLPKYFSSTYDVDLKIVLLPMIIMYLLSDVGSILGGWVSSKL
HHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQTGHSVNFARKVTMIGAGLCVLPLLFVTGLENMWLAVVLIGIALAGHQAFSSTILSIPP
HHCCCCCHHHHHHHHHHCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DMFPKRAVGSVIGLGGFMGGVGGMIMAKSTGLVLDATGGNYTLIFAACTTVYFLAVLAVH
CCCCHHHHHHHHHHHHHHHHHCCEEEEECCCEEEECCCCCEEEHHHHHHHHHHHHHHHHH
ILSPRLAPVSVEGAK
HHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: galacturonate [Periplasm]; Proton [Periplasm]; glucuronate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + galacturonate [Periplasm] = galacturonate [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + glucuronate [Periplasm] = Proton [Cytoplasm] + glucuronate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]