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The map label for this gene is uxaA [H]

Identifier: 103488519

GI number: 103488519

Start: 3192930

End: 3194432

Strand: Reverse

Name: uxaA [H]

Synonym: Sala_3043

Alternate gene names: 103488519

Gene position: 3194432-3192930 (Counterclockwise)

Preceding gene: 103488524

Following gene: 103488516

Centisome position: 95.49

GC content: 67.66

Gene sequence:

>1503_bases
GTGTCAAAGGCAAGCGAATATCCGATGAATCGCGCGATCCGTATCGGCGACGGCGACAATGTGGCGACCGCGATCGCGGA
TATTGCGCCGGGCCAGCTGCTGTTCGCCGATGAGGATATTCGCGCTGCGGCTGCGGTGCCGCGCGGACACAAAATCGCCC
TCGCGGCGATCGCGCGCGGCTCGCCGGTGGTCAAATATGGCTTCCCCATCGGGCGCGCCGCCGCGAACATCGCACCGGGC
GAGCCTGTTCACCGCCATAATCTGGCGACTGCGCTCGGCGACAAGGGCGATTATCATTATAGTCCGCAGCCGGTTCAGGC
CGCCGCCGCGGCACCATCGACGGCTTTTCGCGGCTATGTCCGCGCCGACGGGCGCGTTGGCACACGCAATGAAATCTGGA
TCCTGCCGACCGTCGGCTGCGTCGGCAATCTCGCCGCGCGCGTTGCGCGGATCGCGGGCGAACGCCATGCCGGGCGCGTC
GACGGCGTCCACGCCTTCAAGCATCCCTTCGGCTGTTCGCAGCTCGGTGATGATCTGGGCCATACGCGCAAGCTGCTCGC
GGCGCTTGCGCAGCACCCCAATGCCGGCGGCGTGCTCATCGTCGCCCTGGGGTGCGAGAGCAACCAGCTCGGCGCGCTGC
TCGACCTGATTCCCGCCGATCGCCGCGCGCATATCCGCACGCTGTCGGCGCAGGCGGTTGAGGACGACGAAGCCGCGTGC
CTCGCGCTGATCGACGAGCTGGTCGAGCATTGCGGCGATATGGTGCGGACCGAAGCGCCGCTGTCGAAGCTGGTGCTTGG
GGTCAAATGCGGCGGATCGGACGGGCTTTCGGGCCTCACCGCCAACCCCCTCGTCGGGCGCATGGCCGATGCGGTCGCGG
CGGCGGGCGGCAAGGTGGTGCTGACCGAGATCCCAGAGATTTTCGGTGCCGAACAATTGTTGATGGATCGCGCTGTGTCG
CGCGCGGTATTCGACGATACGGTCGCGCTCGTCCACGACTTCAAGGACTATTTCATCCGCCACGGCGAGCCGGTGAGCGA
AAATCCCTCACCCGGCAATATCGCCGGCGGGATCACGACGCTGGAGGAAAAGTCGCTCGGCGCGGTGCAAAAGGGCGGGC
GGGTGCCGCTCGTCGATGTCCAGCGCTATGGCGGCGAGGCGCGCCTGCCCGGCCTGACCCTGCTCGAAGCACCGGGCAAC
GACGCCGTCTCCTCGACCGCGCTGACCGCGGCGGGCGCGACGATCATCCTCTTCACCACCGGACGCGGCACCCCGCTCGG
CTTTCCGGCGCCGACGCTCAAGATCGCGTCGAACAGCGACCTCGCGGCGCGCAAGGCGGGGTGGATCGACTTCGACGCGG
GGCGAGTGCTGGACAACGGCTTCGAGCGGTCGGCCGAGGCCCTGCTCGACCTGATCGCCGCCACCGCTTCGGGCGCCCCG
ACCAAAGCCGAAGCAAATGAGGAGCGCGACATCGCGATCTGGAAATCGGGCGTGACGCTTTAA

Upstream 100 bases:

>100_bases
CGCACGCGCGTCGATAAATGCGCGCGCCACATTTTCCGGATCGCTGGTTGCCGCCATCTTTCCCATTTCCCTCTTCCGCG
AAGCGGTGTAAGAGACACCG

Downstream 100 bases:

>100_bases
TCGAGCGCGCGGAAGGTGAAATTGCGAAAGCGCGCCTCGCCGGCGCCCGCCGAATAGAGGCCGGGGCGCAGCATCAGGAA
GCCGCCGCGCACATTATGGT

Product: Altronate dehydratase

Products: NA

Alternate protein names: Altronic acid hydratase [H]

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MSKASEYPMNRAIRIGDGDNVATAIADIAPGQLLFADEDIRAAAAVPRGHKIALAAIARGSPVVKYGFPIGRAAANIAPG
EPVHRHNLATALGDKGDYHYSPQPVQAAAAAPSTAFRGYVRADGRVGTRNEIWILPTVGCVGNLAARVARIAGERHAGRV
DGVHAFKHPFGCSQLGDDLGHTRKLLAALAQHPNAGGVLIVALGCESNQLGALLDLIPADRRAHIRTLSAQAVEDDEAAC
LALIDELVEHCGDMVRTEAPLSKLVLGVKCGGSDGLSGLTANPLVGRMADAVAAAGGKVVLTEIPEIFGAEQLLMDRAVS
RAVFDDTVALVHDFKDYFIRHGEPVSENPSPGNIAGGITTLEEKSLGAVQKGGRVPLVDVQRYGGEARLPGLTLLEAPGN
DAVSSTALTAAGATIILFTTGRGTPLGFPAPTLKIASNSDLAARKAGWIDFDAGRVLDNGFERSAEALLDLIAATASGAP
TKAEANEERDIAIWKSGVTL

Sequences:

>Translated_500_residues
MSKASEYPMNRAIRIGDGDNVATAIADIAPGQLLFADEDIRAAAAVPRGHKIALAAIARGSPVVKYGFPIGRAAANIAPG
EPVHRHNLATALGDKGDYHYSPQPVQAAAAAPSTAFRGYVRADGRVGTRNEIWILPTVGCVGNLAARVARIAGERHAGRV
DGVHAFKHPFGCSQLGDDLGHTRKLLAALAQHPNAGGVLIVALGCESNQLGALLDLIPADRRAHIRTLSAQAVEDDEAAC
LALIDELVEHCGDMVRTEAPLSKLVLGVKCGGSDGLSGLTANPLVGRMADAVAAAGGKVVLTEIPEIFGAEQLLMDRAVS
RAVFDDTVALVHDFKDYFIRHGEPVSENPSPGNIAGGITTLEEKSLGAVQKGGRVPLVDVQRYGGEARLPGLTLLEAPGN
DAVSSTALTAAGATIILFTTGRGTPLGFPAPTLKIASNSDLAARKAGWIDFDAGRVLDNGFERSAEALLDLIAATASGAP
TKAEANEERDIAIWKSGVTL
>Mature_499_residues
SKASEYPMNRAIRIGDGDNVATAIADIAPGQLLFADEDIRAAAAVPRGHKIALAAIARGSPVVKYGFPIGRAAANIAPGE
PVHRHNLATALGDKGDYHYSPQPVQAAAAAPSTAFRGYVRADGRVGTRNEIWILPTVGCVGNLAARVARIAGERHAGRVD
GVHAFKHPFGCSQLGDDLGHTRKLLAALAQHPNAGGVLIVALGCESNQLGALLDLIPADRRAHIRTLSAQAVEDDEAACL
ALIDELVEHCGDMVRTEAPLSKLVLGVKCGGSDGLSGLTANPLVGRMADAVAAAGGKVVLTEIPEIFGAEQLLMDRAVSR
AVFDDTVALVHDFKDYFIRHGEPVSENPSPGNIAGGITTLEEKSLGAVQKGGRVPLVDVQRYGGEARLPGLTLLEAPGND
AVSSTALTAAGATIILFTTGRGTPLGFPAPTLKIASNSDLAARKAGWIDFDAGRVLDNGFERSAEALLDLIAATASGAPT
KAEANEERDIAIWKSGVTL

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789475, Length=494, Percent_Identity=48.582995951417, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI1789516, Length=495, Percent_Identity=30.5050505050505, Blast_Score=198, Evalue=7e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.7 [H]

Molecular weight: Translated: 51855; Mature: 51724

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKASEYPMNRAIRIGDGDNVATAIADIAPGQLLFADEDIRAAAAVPRGHKIALAAIARG
CCCCCCCCCCCEEEECCCCCHHHHHHHCCCCEEEEECCCCHHHHCCCCCCEEEEEEEECC
SPVVKYGFPIGRAAANIAPGEPVHRHNLATALGDKGDYHYSPQPVQAAAAAPSTAFRGYV
CCEEEECCCCCHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCHHHCCEE
RADGRVGTRNEIWILPTVGCVGNLAARVARIAGERHAGRVDGVHAFKHPFGCSQLGDDLG
EECCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCHHHHHHHHH
HTRKLLAALAQHPNAGGVLIVALGCESNQLGALLDLIPADRRAHIRTLSAQAVEDDEAAC
HHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHCCCCCHHHHEEHHHHHCCCCHHHH
LALIDELVEHCGDMVRTEAPLSKLVLGVKCGGSDGLSGLTANPLVGRMADAVAAAGGKVV
HHHHHHHHHHHHHHHHCCCCHHHEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCEEE
LTEIPEIFGAEQLLMDRAVSRAVFDDTVALVHDFKDYFIRHGEPVSENPSPGNIAGGITT
EECCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
LEEKSLGAVQKGGRVPLVDVQRYGGEARLPGLTLLEAPGNDAVSSTALTAAGATIILFTT
HHHHHCCHHHCCCCCCEEEHHHCCCCCCCCCEEEEECCCCCCHHHHHHEECCCEEEEEEC
GRGTPLGFPAPTLKIASNSDLAARKAGWIDFDAGRVLDNGFERSAEALLDLIAATASGAP
CCCCCCCCCCCCEEEECCCCCHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
TKAEANEERDIAIWKSGVTL
CCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure 
SKASEYPMNRAIRIGDGDNVATAIADIAPGQLLFADEDIRAAAAVPRGHKIALAAIARG
CCCCCCCCCCEEEECCCCCHHHHHHHCCCCEEEEECCCCHHHHCCCCCCEEEEEEEECC
SPVVKYGFPIGRAAANIAPGEPVHRHNLATALGDKGDYHYSPQPVQAAAAAPSTAFRGYV
CCEEEECCCCCHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCHHHCCEE
RADGRVGTRNEIWILPTVGCVGNLAARVARIAGERHAGRVDGVHAFKHPFGCSQLGDDLG
EECCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCHHHHHHHHH
HTRKLLAALAQHPNAGGVLIVALGCESNQLGALLDLIPADRRAHIRTLSAQAVEDDEAAC
HHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHCCCCCHHHHEEHHHHHCCCCHHHH
LALIDELVEHCGDMVRTEAPLSKLVLGVKCGGSDGLSGLTANPLVGRMADAVAAAGGKVV
HHHHHHHHHHHHHHHHCCCCHHHEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCEEE
LTEIPEIFGAEQLLMDRAVSRAVFDDTVALVHDFKDYFIRHGEPVSENPSPGNIAGGITT
EECCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
LEEKSLGAVQKGGRVPLVDVQRYGGEARLPGLTLLEAPGNDAVSSTALTAAGATIILFTT
HHHHHCCHHHCCCCCCEEEHHHCCCCCCCCCEEEEECCCCCCHHHHHHEECCCEEEEEEC
GRGTPLGFPAPTLKIASNSDLAARKAGWIDFDAGRVLDNGFERSAEALLDLIAATASGAP
CCCCCCCCCCCCEEEECCCCCHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
TKAEANEERDIAIWKSGVTL
CCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 3038546 [H]