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The map label for this gene is ribH

Identifier: 103488459

GI number: 103488459

Start: 3125493

End: 3125918

Strand: Direct

Name: ribH

Synonym: Sala_2982

Alternate gene names: 103488459

Gene position: 3125493-3125918 (Clockwise)

Preceding gene: 103488458

Following gene: 103488462

Centisome position: 93.43

GC content: 63.62

Gene sequence:

>426_bases
ATGGCGCACGTCCTGATCGTCGAAGCGCGTTTCTACAGCCATTTGAACGACATGCTGCTCGATGGCGTGCGCAGCGCGCT
CGATGCCGAAGGGCATAGCCATGAAACGGTGACCGTCCCCGGCGCGCTCGAAGTGCCCGCGGCGATCGCGCTCGCCGCCG
ATAGCGGACGCTTCGACGCCTATGTCGCGCTCGGCGTGGTGATCCGCGGCGAAACCTATCATTTCGAGGTCGTCTCGAAC
GAAAGCGCGCGCGGCATCATGGCATTGACACTCGACGGGCTCGCGATCGGCAACGGCATCCTCACTGTCGAGAATGAAGA
ACAGGCGCTTGCGCGCGCCGACAAGACGCGCAAGGATAAGGGCGGCGAGGCGGCGAAGGCCGCGCTCGCGATGCTCGCGC
TCAAGGAACAATTCGGTATTGGTTGA

Upstream 100 bases:

>100_bases
ACGCGATGGAACTGCTCACCCCCACCCACAGCAATATCGTCGGGCTCGAAGGCTATGGCCTGTCGGTCGTCGGCGAACGC
CCCATTCCCGGAGAAGCCTG

Downstream 100 bases:

>100_bases
TCGTCCGCCTCCCAGCCGTTTTTCCGTCGTCGAGCGCAGCGGGCGGCTGGTGGTGATCGACCGCGAAACCGGGCAGACCC
CGCCGACGGCGGCCGAACGT

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MAHVLIVEARFYSHLNDMLLDGVRSALDAEGHSHETVTVPGALEVPAAIALAADSGRFDAYVALGVVIRGETYHFEVVSN
ESARGIMALTLDGLAIGNGILTVENEEQALARADKTRKDKGGEAAKAALAMLALKEQFGIG

Sequences:

>Translated_141_residues
MAHVLIVEARFYSHLNDMLLDGVRSALDAEGHSHETVTVPGALEVPAAIALAADSGRFDAYVALGVVIRGETYHFEVVSN
ESARGIMALTLDGLAIGNGILTVENEEQALARADKTRKDKGGEAAKAALAMLALKEQFGIG
>Mature_140_residues
AHVLIVEARFYSHLNDMLLDGVRSALDAEGHSHETVTVPGALEVPAAIALAADSGRFDAYVALGVVIRGETYHFEVVSNE
SARGIMALTLDGLAIGNGILTVENEEQALARADKTRKDKGGEAAKAALAMLALKEQFGIG

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=136, Percent_Identity=41.9117647058824, Blast_Score=91, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_SPHAL (Q1GNT5)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_618020.1
- ProteinModelPortal:   Q1GNT5
- SMR:   Q1GNT5
- GeneID:   4083065
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_2982
- NMPDR:   fig|317655.9.peg.2839
- HOGENOM:   HBG311126
- OMA:   LGLQGAC
- ProtClustDB:   PRK00061
- BioCyc:   SALA317655:SALA_2982-MONOMER
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 14844; Mature: 14713

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHVLIVEARFYSHLNDMLLDGVRSALDAEGHSHETVTVPGALEVPAAIALAADSGRFDA
CCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCEEEEEEECCCCCEE
YVALGVVIRGETYHFEVVSNESARGIMALTLDGLAIGNGILTVENEEQALARADKTRKDK
EEEEEEEEECCEEEEEEECCCCCCEEEEEEECCEEECCCEEEEECHHHHHHHHHHCCCCC
GGEAAKAALAMLALKEQFGIG
CCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AHVLIVEARFYSHLNDMLLDGVRSALDAEGHSHETVTVPGALEVPAAIALAADSGRFDA
CEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCEEEEEEECCCCCEE
YVALGVVIRGETYHFEVVSNESARGIMALTLDGLAIGNGILTVENEEQALARADKTRKDK
EEEEEEEEECCEEEEEEECCCCCCEEEEEEECCEEECCCEEEEECHHHHHHHHHHCCCCC
GGEAAKAALAMLALKEQFGIG
CCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA