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The map label for this gene is pbpG [H]

Identifier: 103488453

GI number: 103488453

Start: 3119435

End: 3121633

Strand: Direct

Name: pbpG [H]

Synonym: Sala_2976

Alternate gene names: 103488453

Gene position: 3119435-3121633 (Clockwise)

Preceding gene: 103488452

Following gene: 103488457

Centisome position: 93.25

GC content: 67.94

Gene sequence:

>2199_bases
GTGAGAGAAGGAATACGGGCTTTGCGCCGCGAGAGACAGCAAGCTTCGTCGAATAAATCGTCATCGCCCGGTAAAGGCAG
CGGCTCGCCCCGCGGTGCGCCGTCACGCCTGCGCCTGTGGCTGCGCCGCATCTTTCGCTGGGGGCTGGGGCTCGCCGTCG
TCGGCCTCGTCGCGCTGGGCGTCGCGGTCGGCATCGCCGTGCAGCGAATGCCGAGTTTCGAGGAGCTCAAGAAATCGCCC
GCGGGGCAGACGATCCGCGTCCGCGCCGCCGACGGCACCGTCTTTCTGTCACTGGGCCCCAATTACGGCCGCTGGCTGTC
GCTCGGCGAAACGCCGCAGGTGATGCAGGATGCGATGGTCGCGGTCGAGGATCGCCGCTTTCGCTATCATCCCGGCCTCG
ATCCGGTCGGCATGGCGCGCGCCGCGGTCTTTGCCGTCGAGAATTACGGCACCGGGCGGCGGATGCAGGGCGCCTCGACG
ATCACGCAGCAGCTGGCGCGCAATATCTTCCTGTCGAACAGCTATACCTGGGCGCGCAAGGCGCGCGAGATGATCCTCGC
GCTCGCGCTCGAATGGAAATTCTCGAAAGACCAGATCCTCGAACTCTATCTGAACAAGGTCTATTTCGGCGGCGGCAGCT
ATGGCATCGACGCCGCGTCGAACAGCTTTTTCGGTCATAGCGCGACCGAAATGTCGCTGTCGGAAGCCGCGGTGATCGCC
GGGCTCGTCAAGGCGCCGTCGCGCTATTCGCCGACCGCCGATGCCCAGGCCGCGCTCGGCCGCGCCGACGTCGTGCTCGA
CGTCATGGTCGATGCGGGGGTCATCACCCACGCGCAGGCCGAAGCAGCGGAACCCGCGAATGTTCAGCTTGCCAAGGAAA
CGGGGCAGAACAGCGCGCGTTACTTCACCGACTGGGCGTTGCCGCAGCTCGACATGCTGATCGACGAAGGCAGCGAGGCG
CTCGACGTCTACACGACGATCGACCTCAACATGCAGCGCGCCGCGACGGCATCGATCCAGGCGAACACGCCGCCGGGCGT
GCAGGGCGCGCTCGTGTCGCTCGACCGCGACGGCGCGGTGCGCGCGATGGTCGGCGGCCGCGACTATGTGACCTCCAACT
ATAATCGCGCGACGCAGGCGCTGCGCCAGCCGGGATCGGCGTGGAAGCTGTTCGTCTATATGGCCGCGCTCGAGGCGGGC
TATAAGGTCGACGATCCCGTGGTCGACGAGCCGGTGACGATCAACGGCTGGAGCCCGCGAAACTCGTCGGGCCGCTTTGC
GGGCACGATGGATTTGCGCAGCGCCTTTGCCTATTCGGTCAACACCGTCGCGGCCAAGCTGGGCGATGAAATCGGCTTTT
CGGCGGTTGCCAACATGGCACGCCGTTTCGGCATCACCACGCCCGTCAACACGCACCCGTCGATGGTGCTGGGAAGCGCC
GAGGTGCGCGTGATCGACATGACCGCCGCCTTTGCCGCGGTGGCGCGCGGGGGCGTGTCGGTGCAGCCCTATGGCATCAC
CAGGGTGACGACCGCGAGCGGCGAGCTGCTCTATCAGCGGCCTGCCGAGCGCGGCAGCACGCTGGTCGATCCCTGGGTGG
CGGCCGGGATCACCGACCTGCTCCAGACCGCGGTCAACACCGGCACCGGGCGCGCGGCGCAGATCGGCCGTCCGGTCGCG
GGCAAGACAGGGACGACGTCGAGCAACAAGGACGGGTGGTTCCTCGGCTTTTCGAGCGGCCTTACGACGGGCGTGTGGAT
GGGCCGCGACGATGCGAAACCCGTCGGCGGGTTGCAGGGCGGCCGCGCGCCGGCCAAGGCCTTCGCCGACTATATGCGCG
TCGCGGTTGCGCGGCGCCCGGTCGAGCAATTCGATACCGAGGTCGTGCTGCCCGAATGGCAGTTGGAGGACGAGGGCGAG
GCCTATCTGGGCGAGCCGGGCGAGGAAGGCATGCTCGTCGACGAAAATGGCATGCCGATCGAACTGCCCTATGACAGCCG
CCCGCCCGACAGTTTCGGCACGCCGCCCGCGGTCGAAGCTCCGGTGCTCGACCAGCAATGGATCGAGGAGCAGACGGGGC
GCCGCCCGCCCGCAAACGGGGGCGGCGGCCAGCCCAAGGTGATTTCGGTCCCGAAAGCGCCGCCGCCCCAGGTCCGCGTG
CCGCCGCCGCGGCCCGCTCCCGTCGAACCCGCGGATTGA

Upstream 100 bases:

>100_bases
TGCATCAACAGCGCGGCGCTTGACTTCGCCGACCGCGCGCCGGATGAGGCGTCAACCGGCGAGGGCTGAACCCTTCGCGG
ACTGACGCATCAGGGGCGCA

Downstream 100 bases:

>100_bases
GCGCGCTCAGGCGGTAAAGCGATAACGGTGCAGCGCGCGCCCTTCGCGCCGCAGCCAGCCGCGCGCCGCGGCGACGTCGC
CGTCGTGCAGCGTGGCGACG

Product: penicillin-binding protein 1A

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 732; Mature: 732

Protein sequence:

>732_residues
MREGIRALRRERQQASSNKSSSPGKGSGSPRGAPSRLRLWLRRIFRWGLGLAVVGLVALGVAVGIAVQRMPSFEELKKSP
AGQTIRVRAADGTVFLSLGPNYGRWLSLGETPQVMQDAMVAVEDRRFRYHPGLDPVGMARAAVFAVENYGTGRRMQGAST
ITQQLARNIFLSNSYTWARKAREMILALALEWKFSKDQILELYLNKVYFGGGSYGIDAASNSFFGHSATEMSLSEAAVIA
GLVKAPSRYSPTADAQAALGRADVVLDVMVDAGVITHAQAEAAEPANVQLAKETGQNSARYFTDWALPQLDMLIDEGSEA
LDVYTTIDLNMQRAATASIQANTPPGVQGALVSLDRDGAVRAMVGGRDYVTSNYNRATQALRQPGSAWKLFVYMAALEAG
YKVDDPVVDEPVTINGWSPRNSSGRFAGTMDLRSAFAYSVNTVAAKLGDEIGFSAVANMARRFGITTPVNTHPSMVLGSA
EVRVIDMTAAFAAVARGGVSVQPYGITRVTTASGELLYQRPAERGSTLVDPWVAAGITDLLQTAVNTGTGRAAQIGRPVA
GKTGTTSSNKDGWFLGFSSGLTTGVWMGRDDAKPVGGLQGGRAPAKAFADYMRVAVARRPVEQFDTEVVLPEWQLEDEGE
AYLGEPGEEGMLVDENGMPIELPYDSRPPDSFGTPPAVEAPVLDQQWIEEQTGRRPPANGGGGQPKVISVPKAPPPQVRV
PPPRPAPVEPAD

Sequences:

>Translated_732_residues
MREGIRALRRERQQASSNKSSSPGKGSGSPRGAPSRLRLWLRRIFRWGLGLAVVGLVALGVAVGIAVQRMPSFEELKKSP
AGQTIRVRAADGTVFLSLGPNYGRWLSLGETPQVMQDAMVAVEDRRFRYHPGLDPVGMARAAVFAVENYGTGRRMQGAST
ITQQLARNIFLSNSYTWARKAREMILALALEWKFSKDQILELYLNKVYFGGGSYGIDAASNSFFGHSATEMSLSEAAVIA
GLVKAPSRYSPTADAQAALGRADVVLDVMVDAGVITHAQAEAAEPANVQLAKETGQNSARYFTDWALPQLDMLIDEGSEA
LDVYTTIDLNMQRAATASIQANTPPGVQGALVSLDRDGAVRAMVGGRDYVTSNYNRATQALRQPGSAWKLFVYMAALEAG
YKVDDPVVDEPVTINGWSPRNSSGRFAGTMDLRSAFAYSVNTVAAKLGDEIGFSAVANMARRFGITTPVNTHPSMVLGSA
EVRVIDMTAAFAAVARGGVSVQPYGITRVTTASGELLYQRPAERGSTLVDPWVAAGITDLLQTAVNTGTGRAAQIGRPVA
GKTGTTSSNKDGWFLGFSSGLTTGVWMGRDDAKPVGGLQGGRAPAKAFADYMRVAVARRPVEQFDTEVVLPEWQLEDEGE
AYLGEPGEEGMLVDENGMPIELPYDSRPPDSFGTPPAVEAPVLDQQWIEEQTGRRPPANGGGGQPKVISVPKAPPPQVRV
PPPRPAPVEPAD
>Mature_732_residues
MREGIRALRRERQQASSNKSSSPGKGSGSPRGAPSRLRLWLRRIFRWGLGLAVVGLVALGVAVGIAVQRMPSFEELKKSP
AGQTIRVRAADGTVFLSLGPNYGRWLSLGETPQVMQDAMVAVEDRRFRYHPGLDPVGMARAAVFAVENYGTGRRMQGAST
ITQQLARNIFLSNSYTWARKAREMILALALEWKFSKDQILELYLNKVYFGGGSYGIDAASNSFFGHSATEMSLSEAAVIA
GLVKAPSRYSPTADAQAALGRADVVLDVMVDAGVITHAQAEAAEPANVQLAKETGQNSARYFTDWALPQLDMLIDEGSEA
LDVYTTIDLNMQRAATASIQANTPPGVQGALVSLDRDGAVRAMVGGRDYVTSNYNRATQALRQPGSAWKLFVYMAALEAG
YKVDDPVVDEPVTINGWSPRNSSGRFAGTMDLRSAFAYSVNTVAAKLGDEIGFSAVANMARRFGITTPVNTHPSMVLGSA
EVRVIDMTAAFAAVARGGVSVQPYGITRVTTASGELLYQRPAERGSTLVDPWVAAGITDLLQTAVNTGTGRAAQIGRPVA
GKTGTTSSNKDGWFLGFSSGLTTGVWMGRDDAKPVGGLQGGRAPAKAFADYMRVAVARRPVEQFDTEVVLPEWQLEDEGE
AYLGEPGEEGMLVDENGMPIELPYDSRPPDSFGTPPAVEAPVLDQQWIEEQTGRRPPANGGGGQPKVISVPKAPPPQVRV
PPPRPAPVEPAD

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=606, Percent_Identity=32.5082508250825, Blast_Score=218, Evalue=1e-57,
Organism=Escherichia coli, GI1788867, Length=530, Percent_Identity=30.5660377358491, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI87082258, Length=311, Percent_Identity=36.9774919614148, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI1789601, Length=172, Percent_Identity=33.7209302325581, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 78286; Mature: 78286

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREGIRALRRERQQASSNKSSSPGKGSGSPRGAPSRLRLWLRRIFRWGLGLAVVGLVALG
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAVGIAVQRMPSFEELKKSPAGQTIRVRAADGTVFLSLGPNYGRWLSLGETPQVMQDAMV
HHHHHHHHCCCCHHHHHCCCCCCEEEEEECCCEEEEEECCCCCCEEECCCCHHHHHHHHH
AVEDRRFRYHPGLDPVGMARAAVFAVENYGTGRRMQGASTITQQLARNIFLSNSYTWARK
HHHCCCEEECCCCCHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHH
AREMILALALEWKFSKDQILELYLNKVYFGGGSYGIDAASNSFFGHSATEMSLSEAAVIA
HHHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
GLVKAPSRYSPTADAQAALGRADVVLDVMVDAGVITHAQAEAAEPANVQLAKETGQNSAR
HHHHCCCCCCCCCCHHHHCCCHHEEEEEHHCCCEEEECHHCCCCCCCEEEEHHCCCCCCE
YFTDWALPQLDMLIDEGSEALDVYTTIDLNMQRAATASIQANTPPGVQGALVSLDRDGAV
EEECCCCCHHHHHHHCCCCEEEEEEEEECCHHHHEEEEEECCCCCCCCCEEEEECCCCCE
RAMVGGRDYVTSNYNRATQALRQPGSAWKLFVYMAALEAGYKVDDPVVDEPVTINGWSPR
EEEECCCHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCC
NSSGRFAGTMDLRSAFAYSVNTVAAKLGDEIGFSAVANMARRFGITTPVNTHPSMVLGSA
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEECCC
EVRVIDMTAAFAAVARGGVSVQPYGITRVTTASGELLYQRPAERGSTLVDPWVAAGITDL
CEEEEEHHHHHHHHHCCCCEECCCCCEEEEECCCCEEEECCHHCCCCCCCHHHHHHHHHH
LQTAVNTGTGRAAQIGRPVAGKTGTTSSNKDGWFLGFSSGLTTGVWMGRDDAKPVGGLQG
HHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEECCCCCCCCCCCCC
GRAPAKAFADYMRVAVARRPVEQFDTEVVLPEWQLEDEGEAYLGEPGEEGMLVDENGMPI
CCCHHHHHHHHHHHHHHHCCHHHHCCEEECCCCCCCCCCCEECCCCCCCCEEECCCCCEE
ELPYDSRPPDSFGTPPAVEAPVLDQQWIEEQTGRRPPANGGGGQPKVISVPKAPPPQVRV
ECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCEEC
PPPRPAPVEPAD
CCCCCCCCCCCC
>Mature Secondary Structure
MREGIRALRRERQQASSNKSSSPGKGSGSPRGAPSRLRLWLRRIFRWGLGLAVVGLVALG
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAVGIAVQRMPSFEELKKSPAGQTIRVRAADGTVFLSLGPNYGRWLSLGETPQVMQDAMV
HHHHHHHHCCCCHHHHHCCCCCCEEEEEECCCEEEEEECCCCCCEEECCCCHHHHHHHHH
AVEDRRFRYHPGLDPVGMARAAVFAVENYGTGRRMQGASTITQQLARNIFLSNSYTWARK
HHHCCCEEECCCCCHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHH
AREMILALALEWKFSKDQILELYLNKVYFGGGSYGIDAASNSFFGHSATEMSLSEAAVIA
HHHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
GLVKAPSRYSPTADAQAALGRADVVLDVMVDAGVITHAQAEAAEPANVQLAKETGQNSAR
HHHHCCCCCCCCCCHHHHCCCHHEEEEEHHCCCEEEECHHCCCCCCCEEEEHHCCCCCCE
YFTDWALPQLDMLIDEGSEALDVYTTIDLNMQRAATASIQANTPPGVQGALVSLDRDGAV
EEECCCCCHHHHHHHCCCCEEEEEEEEECCHHHHEEEEEECCCCCCCCCEEEEECCCCCE
RAMVGGRDYVTSNYNRATQALRQPGSAWKLFVYMAALEAGYKVDDPVVDEPVTINGWSPR
EEEECCCHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCC
NSSGRFAGTMDLRSAFAYSVNTVAAKLGDEIGFSAVANMARRFGITTPVNTHPSMVLGSA
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEECCC
EVRVIDMTAAFAAVARGGVSVQPYGITRVTTASGELLYQRPAERGSTLVDPWVAAGITDL
CEEEEEHHHHHHHHHCCCCEECCCCCEEEEECCCCEEEECCHHCCCCCCCHHHHHHHHHH
LQTAVNTGTGRAAQIGRPVAGKTGTTSSNKDGWFLGFSSGLTTGVWMGRDDAKPVGGLQG
HHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEECCCCCCCCCCCCC
GRAPAKAFADYMRVAVARRPVEQFDTEVVLPEWQLEDEGEAYLGEPGEEGMLVDENGMPI
CCCHHHHHHHHHHHHHHHCCHHHHCCEEECCCCCCCCCCCEECCCCCCCCEEECCCCCEE
ELPYDSRPPDSFGTPPAVEAPVLDQQWIEEQTGRRPPANGGGGQPKVISVPKAPPPQVRV
ECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCEEC
PPPRPAPVEPAD
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]