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The map label for this gene is hisN [H]

Identifier: 103488418

GI number: 103488418

Start: 3084324

End: 3085106

Strand: Reverse

Name: hisN [H]

Synonym: Sala_2941

Alternate gene names: 103488418

Gene position: 3085106-3084324 (Counterclockwise)

Preceding gene: 103488419

Following gene: 103488417

Centisome position: 92.23

GC content: 68.2

Gene sequence:

>783_bases
ATGTCGATCGTGTCAGACCTTGCACTCGCCAACCGCCTCGCCGACGCCGCCGGCGACGCGATCCGTCCGTTCTTTCGCGC
CCGCTGGGCGCACGAAGCGAAGGCCGACGCCTCGCCGGTGACCGAGGCCGACCGCGCCGCCGAAGCCGCGATGCGCCGCC
TGCTCGATGCCGAAGCGCCGCGCGATGGCATCATTGGCGAGGAATATGGGGCCGAGCGCCCCGAAGCGGCACGGCAATGG
GTGCTCGACCCGATCGACGGCACGGTGAGCTTCATGGCCGGGCGCCCGATCTTCGGCACGCTGATCGCGCTTCTGCAGGA
CGGCTGGCCGCTCATCGGGATCATCGACCAGCCGATCACCGGCGAGCGCTGGGTCGGCGCGACGGGACATCCGACGCTGT
TGGGCGGCAAACCCGCGACGACGCGCGCCTGCCGCAGTCTGTCCGACGCGGTGCTCGCGACCACCGGTCCGCAATATTTC
AGCGATCATGACGGCGAGCATTTCATGGCGCTCGCCGCAAAGACGGCGCACAAGCGGATGGTCTTCGGCGGCGACTGCTA
TAATTATGGCCTGCTCAGCTCGGGTCACATCGACCTGGTCGTCGAGGCGGGGCTCAAGCTCCACGACTTTGCCGCGCTCG
TGCCCATCGTCGAAGGCGCGGGGGGCACGATGTGCGACTGGAACGGCGATCCGCTGAATAGCGACAGCGCGGGCCATGTC
ATCGCGCTCGGCGATCCGGCGCGGCTCGAGGATGTGATCGAAGGGCTCGCCTGCGATCATTGA

Upstream 100 bases:

>100_bases
AAACGAGCGTCTCCTCGCTCTTTGACTGAAAGCCGCGACGGGGACGGGAAAAATGCTGCGCAGGCTGGCGGCGCGAACCC
GGCTGCGCTAGCGCAACGTC

Downstream 100 bases:

>100_bases
GAGGCGCGCTTACAATGCTTGCATTTCCCGGCGAATCCGCATAAGCGCGCGCCTTCCGATTGTGTCGGCTGGCTGAAAGG
GCTGCCAGGCCGGCACCAGA

Product: histidinol-phosphate phosphatase, putative, inositol monophosphatase

Products: NA

Alternate protein names: HolPase; Histidinol-phosphate phosphatase [H]

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MSIVSDLALANRLADAAGDAIRPFFRARWAHEAKADASPVTEADRAAEAAMRRLLDAEAPRDGIIGEEYGAERPEAARQW
VLDPIDGTVSFMAGRPIFGTLIALLQDGWPLIGIIDQPITGERWVGATGHPTLLGGKPATTRACRSLSDAVLATTGPQYF
SDHDGEHFMALAAKTAHKRMVFGGDCYNYGLLSSGHIDLVVEAGLKLHDFAALVPIVEGAGGTMCDWNGDPLNSDSAGHV
IALGDPARLEDVIEGLACDH

Sequences:

>Translated_260_residues
MSIVSDLALANRLADAAGDAIRPFFRARWAHEAKADASPVTEADRAAEAAMRRLLDAEAPRDGIIGEEYGAERPEAARQW
VLDPIDGTVSFMAGRPIFGTLIALLQDGWPLIGIIDQPITGERWVGATGHPTLLGGKPATTRACRSLSDAVLATTGPQYF
SDHDGEHFMALAAKTAHKRMVFGGDCYNYGLLSSGHIDLVVEAGLKLHDFAALVPIVEGAGGTMCDWNGDPLNSDSAGHV
IALGDPARLEDVIEGLACDH
>Mature_259_residues
SIVSDLALANRLADAAGDAIRPFFRARWAHEAKADASPVTEADRAAEAAMRRLLDAEAPRDGIIGEEYGAERPEAARQWV
LDPIDGTVSFMAGRPIFGTLIALLQDGWPLIGIIDQPITGERWVGATGHPTLLGGKPATTRACRSLSDAVLATTGPQYFS
DHDGEHFMALAAKTAHKRMVFGGDCYNYGLLSSGHIDLVVEAGLKLHDFAALVPIVEGAGGTMCDWNGDPLNSDSAGHVI
ALGDPARLEDVIEGLACDH

Specific function: Catalyzes the dephosphorylation of histidinol-phosphate to histidinol, the direct precursor of histidine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788882, Length=246, Percent_Identity=29.6747967479675, Blast_Score=84, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI193202572, Length=238, Percent_Identity=27.7310924369748, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193202570, Length=241, Percent_Identity=27.8008298755187, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24664922, Length=220, Percent_Identity=27.7272727272727, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21357329, Length=230, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011809
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 27563; Mature: 27432

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVSDLALANRLADAAGDAIRPFFRARWAHEAKADASPVTEADRAAEAAMRRLLDAEAP
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCC
RDGIIGEEYGAERPEAARQWVLDPIDGTVSFMAGRPIFGTLIALLQDGWPLIGIIDQPIT
CCCCCCCCCCCCCCHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHCCCCEEEEECCCCC
GERWVGATGHPTLLGGKPATTRACRSLSDAVLATTGPQYFSDHDGEHFMALAAKTAHKRM
CCCEECCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHEE
VFGGDCYNYGLLSSGHIDLVVEAGLKLHDFAALVPIVEGAGGTMCDWNGDPLNSDSAGHV
EECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCE
IALGDPARLEDVIEGLACDH
EEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SIVSDLALANRLADAAGDAIRPFFRARWAHEAKADASPVTEADRAAEAAMRRLLDAEAP
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCC
RDGIIGEEYGAERPEAARQWVLDPIDGTVSFMAGRPIFGTLIALLQDGWPLIGIIDQPIT
CCCCCCCCCCCCCCHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHCCCCEEEEECCCCC
GERWVGATGHPTLLGGKPATTRACRSLSDAVLATTGPQYFSDHDGEHFMALAAKTAHKRM
CCCEECCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHEE
VFGGDCYNYGLLSSGHIDLVVEAGLKLHDFAALVPIVEGAGGTMCDWNGDPLNSDSAGHV
EECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCE
IALGDPARLEDVIEGLACDH
EEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8626508 [H]