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The map label for this gene is yngJ [H]

Identifier: 103488374

GI number: 103488374

Start: 3048634

End: 3050217

Strand: Direct

Name: yngJ [H]

Synonym: Sala_2897

Alternate gene names: 103488374

Gene position: 3048634-3050217 (Clockwise)

Preceding gene: 103488373

Following gene: 103488375

Centisome position: 91.14

GC content: 70.08

Gene sequence:

>1584_bases
TTGCGCTCCGCTCTCCAAGCGGCGCAGGCCTATCGCGACGCGGCGCAGGCGGCGCTTGCCGAACGGCTGGCGGCGCGGCC
GATCGACGAGGAACAGCGCGCCGCGCATGGTTTTGCGTGGGTCGCGACGACGGTTGCGGCGCTCACCGCCGTGCTCGATT
GGTGCGAGTCCGGGGGGGAATCGAACCCGCTCGACGCGAAGGTCGCCACGCTCGCCTTCGCCGAGAGCATCGCCCAGCTC
GTCGGCGGCCTGCCGATGGGGCAGAATGAGATGTTCCGCCCCGCCGACCTTGGCCTCGGTGCGGAGGCACGCGCGCTTGC
CGATGCCTCCGCGGAGCTGCTCGACGCCGGCCACGCCGCGCTGCGCGCCGAGGTGGCCGCCGCGCTCGCGGCGGAGCAAT
GGCCGAGCGAAACGCTCCACGACGCCGACCTCGATGCGATCCGCGACCAGTTTCGCCGCTTCACCGATGCGGAGATCGTG
CCGCACGCGCACCGCTGGCACCTCGCCAACGCGCTGATCCCCGACGCCACTGTGCGGGCGATGGCCGACCTTGGCACCTT
CGGCGTGTGCATTCCCGAAGAGTTTGGCGGACTCGGCCTGTCGAAGCTGGTGATGTGCCTCGTCACCGAGGAATTGTCGC
GCGGCTGGATCGGTGCCGGGTCGCTCGGCACGCGGTCGGAGATTGCGGGCGAGCTGATCGCGACCGGCGGCACCGACGCG
CAGAAAGCCGAATGGCTGCCCAGAATCGCGAGCGGCGCGATACTGCCGACCGCGGTGTTCACCGAACCCGATGTCGGGTC
GGACCTCGGTTCGTTGCAGACGCGCGCGCGGTTCGCGCAGGGCCGCTGGGTGATCGACGGCGCCAAGACGTGGATCACCC
ACGCCGCGCGATCGGACCTGATGACGCTGCTCGCACGCACCCTGCCCGACGCCAGGGGCTATGCCGGCCTCTCGATGCTG
CTTGTTCCCAAGCCGCGCGGCACCGACGCCGACCCCTTCCCCGCCGCAGGCATGAGCGGTAGCGAGATCGCGGTGCTCGG
CTATCGCGGCATGCGCGAATATGCGCTGCAATTCGACGGCATGGCGGCGCCCGCCGACGCGCTGCTCGGCGGCGTCGAGG
GGCAGGGGTTCAAGCAGCTGATGCGCACCTTCGAGGGCGCGCGCATCCAGACCGCGGCGCGCGCGGTGGGCGTGGCGCGA
CGCGCGCTTGAGCTGGGGCTCGATTATGCAATGAACCGCAGGCAGTTCGGCCGGGCGATCATCGCCTTCCCGCGCGTCGC
CGACAAGCTGGCGATGAGCGTGGTCGATTTCGTGATGGCGCGCGAGCTGGCCTATGCCGCGGCGCGCGCCAAGGACAGCG
GCAAGCGCTGCGACATCGAGGCGGGAATGGCAAAGCTGCTCGCCGCGCGCGCCGCCTGGGTGAACGCCGATGCCAGCCTG
CAGATCCACGGCGGCAACGGCTATGCGCTCGAATATGAAATCAGCCGCGTGCTCTGCGACGCGCGTATCCTCAATATCTT
CGAAGGCGCGGCGGAGATTCAGGCGCAGGTGATTGCGCGCGGACTGATCGAAGGCCGCAACTAG

Upstream 100 bases:

>100_bases
GCGAGCTGGGACGTCGCAACGGGCGCTATGGGCTCGAGACGATGTGCATCGGCGGCGGGCAGGGAATCGCCGCGATCTTC
GAGCGCGCGGCCTGATGGGT

Downstream 100 bases:

>100_bases
AGCGCGATGACATGATATTGACCCACCGTGACGGAGGCGCGTCGGCATGTGCGAAGCCACTGCCGGGCAATCGGCCCGGC
GCCGCATCGACCTTGCTGAT

Product: acyl-CoA dehydrogenase-like protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MRSALQAAQAYRDAAQAALAERLAARPIDEEQRAAHGFAWVATTVAALTAVLDWCESGGESNPLDAKVATLAFAESIAQL
VGGLPMGQNEMFRPADLGLGAEARALADASAELLDAGHAALRAEVAAALAAEQWPSETLHDADLDAIRDQFRRFTDAEIV
PHAHRWHLANALIPDATVRAMADLGTFGVCIPEEFGGLGLSKLVMCLVTEELSRGWIGAGSLGTRSEIAGELIATGGTDA
QKAEWLPRIASGAILPTAVFTEPDVGSDLGSLQTRARFAQGRWVIDGAKTWITHAARSDLMTLLARTLPDARGYAGLSML
LVPKPRGTDADPFPAAGMSGSEIAVLGYRGMREYALQFDGMAAPADALLGGVEGQGFKQLMRTFEGARIQTAARAVGVAR
RALELGLDYAMNRRQFGRAIIAFPRVADKLAMSVVDFVMARELAYAAARAKDSGKRCDIEAGMAKLLAARAAWVNADASL
QIHGGNGYALEYEISRVLCDARILNIFEGAAEIQAQVIARGLIEGRN

Sequences:

>Translated_527_residues
MRSALQAAQAYRDAAQAALAERLAARPIDEEQRAAHGFAWVATTVAALTAVLDWCESGGESNPLDAKVATLAFAESIAQL
VGGLPMGQNEMFRPADLGLGAEARALADASAELLDAGHAALRAEVAAALAAEQWPSETLHDADLDAIRDQFRRFTDAEIV
PHAHRWHLANALIPDATVRAMADLGTFGVCIPEEFGGLGLSKLVMCLVTEELSRGWIGAGSLGTRSEIAGELIATGGTDA
QKAEWLPRIASGAILPTAVFTEPDVGSDLGSLQTRARFAQGRWVIDGAKTWITHAARSDLMTLLARTLPDARGYAGLSML
LVPKPRGTDADPFPAAGMSGSEIAVLGYRGMREYALQFDGMAAPADALLGGVEGQGFKQLMRTFEGARIQTAARAVGVAR
RALELGLDYAMNRRQFGRAIIAFPRVADKLAMSVVDFVMARELAYAAARAKDSGKRCDIEAGMAKLLAARAAWVNADASL
QIHGGNGYALEYEISRVLCDARILNIFEGAAEIQAQVIARGLIEGRN
>Mature_527_residues
MRSALQAAQAYRDAAQAALAERLAARPIDEEQRAAHGFAWVATTVAALTAVLDWCESGGESNPLDAKVATLAFAESIAQL
VGGLPMGQNEMFRPADLGLGAEARALADASAELLDAGHAALRAEVAAALAAEQWPSETLHDADLDAIRDQFRRFTDAEIV
PHAHRWHLANALIPDATVRAMADLGTFGVCIPEEFGGLGLSKLVMCLVTEELSRGWIGAGSLGTRSEIAGELIATGGTDA
QKAEWLPRIASGAILPTAVFTEPDVGSDLGSLQTRARFAQGRWVIDGAKTWITHAARSDLMTLLARTLPDARGYAGLSML
LVPKPRGTDADPFPAAGMSGSEIAVLGYRGMREYALQFDGMAAPADALLGGVEGQGFKQLMRTFEGARIQTAARAVGVAR
RALELGLDYAMNRRQFGRAIIAFPRVADKLAMSVVDFVMARELAYAAARAKDSGKRCDIEAGMAKLLAARAAWVNADASL
QIHGGNGYALEYEISRVLCDARILNIFEGAAEIQAQVIARGLIEGRN

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=354, Percent_Identity=31.9209039548023, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI4557233, Length=386, Percent_Identity=35.2331606217617, Blast_Score=179, Evalue=6e-45,
Organism=Homo sapiens, GI4557231, Length=375, Percent_Identity=32, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI187960098, Length=375, Percent_Identity=32, Blast_Score=176, Evalue=6e-44,
Organism=Homo sapiens, GI4557235, Length=353, Percent_Identity=32.2946175637394, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI76496475, Length=353, Percent_Identity=32.0113314447592, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI4501859, Length=392, Percent_Identity=29.5918367346939, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI4501857, Length=380, Percent_Identity=27.1052631578947, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI226958412, Length=380, Percent_Identity=28.1578947368421, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI7656849, Length=417, Percent_Identity=28.2973621103118, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI226958414, Length=347, Percent_Identity=29.3948126801153, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI4503943, Length=385, Percent_Identity=26.4935064935065, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI7669494, Length=372, Percent_Identity=26.0752688172043, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI38505218, Length=333, Percent_Identity=27.027027027027, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI211971008, Length=378, Percent_Identity=26.984126984127, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI48976061, Length=378, Percent_Identity=26.984126984127, Blast_Score=88, Evalue=3e-17,
Organism=Escherichia coli, GI1786223, Length=363, Percent_Identity=27.8236914600551, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI87081958, Length=366, Percent_Identity=28.1420765027322, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71985184, Length=354, Percent_Identity=32.4858757062147, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17569725, Length=382, Percent_Identity=31.9371727748691, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17534899, Length=381, Percent_Identity=32.0209973753281, Blast_Score=169, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI17570075, Length=382, Percent_Identity=29.5811518324607, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17538396, Length=417, Percent_Identity=29.9760191846523, Blast_Score=165, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI17506239, Length=374, Percent_Identity=28.6096256684492, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17508101, Length=371, Percent_Identity=29.3800539083558, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17505929, Length=411, Percent_Identity=25.5474452554745, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71985192, Length=334, Percent_Identity=29.0419161676647, Blast_Score=133, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17533517, Length=382, Percent_Identity=26.4397905759162, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17551932, Length=387, Percent_Identity=25.3229974160207, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI71990804, Length=295, Percent_Identity=30.1694915254237, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17534353, Length=382, Percent_Identity=24.3455497382199, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI32563615, Length=241, Percent_Identity=28.2157676348548, Blast_Score=99, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17562446, Length=376, Percent_Identity=25.2659574468085, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71982178, Length=301, Percent_Identity=23.2558139534884, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI21356377, Length=400, Percent_Identity=33.25, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24660351, Length=376, Percent_Identity=31.6489361702128, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI281363737, Length=386, Percent_Identity=30.8290155440415, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24646207, Length=377, Percent_Identity=30.5039787798408, Blast_Score=159, Evalue=5e-39,
Organism=Drosophila melanogaster, GI21355753, Length=389, Percent_Identity=31.3624678663239, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24666513, Length=389, Percent_Identity=27.5064267352185, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI19920834, Length=387, Percent_Identity=27.390180878553, Blast_Score=120, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 55889; Mature: 55889

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSALQAAQAYRDAAQAALAERLAARPIDEEQRAAHGFAWVATTVAALTAVLDWCESGGE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SNPLDAKVATLAFAESIAQLVGGLPMGQNEMFRPADLGLGAEARALADASAELLDAGHAA
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LRAEVAAALAAEQWPSETLHDADLDAIRDQFRRFTDAEIVPHAHRWHLANALIPDATVRA
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHH
MADLGTFGVCIPEEFGGLGLSKLVMCLVTEELSRGWIGAGSLGTRSEIAGELIATGGTDA
HHHCCCCCEECCHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCH
QKAEWLPRIASGAILPTAVFTEPDVGSDLGSLQTRARFAQGRWVIDGAKTWITHAARSDL
HHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHH
MTLLARTLPDARGYAGLSMLLVPKPRGTDADPFPAAGMSGSEIAVLGYRGMREYALQFDG
HHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHCC
MAAPADALLGGVEGQGFKQLMRTFEGARIQTAARAVGVARRALELGLDYAMNRRQFGRAI
CCCCHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
IAFPRVADKLAMSVVDFVMARELAYAAARAKDSGKRCDIEAGMAKLLAARAAWVNADASL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEE
QIHGGNGYALEYEISRVLCDARILNIFEGAAEIQAQVIARGLIEGRN
EEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRSALQAAQAYRDAAQAALAERLAARPIDEEQRAAHGFAWVATTVAALTAVLDWCESGGE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SNPLDAKVATLAFAESIAQLVGGLPMGQNEMFRPADLGLGAEARALADASAELLDAGHAA
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LRAEVAAALAAEQWPSETLHDADLDAIRDQFRRFTDAEIVPHAHRWHLANALIPDATVRA
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHH
MADLGTFGVCIPEEFGGLGLSKLVMCLVTEELSRGWIGAGSLGTRSEIAGELIATGGTDA
HHHCCCCCEECCHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCH
QKAEWLPRIASGAILPTAVFTEPDVGSDLGSLQTRARFAQGRWVIDGAKTWITHAARSDL
HHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHH
MTLLARTLPDARGYAGLSMLLVPKPRGTDADPFPAAGMSGSEIAVLGYRGMREYALQFDG
HHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHCC
MAAPADALLGGVEGQGFKQLMRTFEGARIQTAARAVGVARRALELGLDYAMNRRQFGRAI
CCCCHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
IAFPRVADKLAMSVVDFVMARELAYAAARAKDSGKRCDIEAGMAKLLAARAAWVNADASL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEE
QIHGGNGYALEYEISRVLCDARILNIFEGAAEIQAQVIARGLIEGRN
EEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]