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The map label for this gene is mmgC [H]

Identifier: 103488356

GI number: 103488356

Start: 3030073

End: 3031275

Strand: Direct

Name: mmgC [H]

Synonym: Sala_2879

Alternate gene names: 103488356

Gene position: 3030073-3031275 (Clockwise)

Preceding gene: 103488355

Following gene: 103488357

Centisome position: 90.58

GC content: 65.25

Gene sequence:

>1203_bases
ATGGCCCTCGCCGATCCGCAGCGCATCGAAGCGCTCGACCCGCTCGATCCCCTCGCGCTCGATGCACAGCTGAGCGAGGA
GGAGCGGATGATCCGCGACGCCGCGCGCTCCTATGCGGAGGGCGAACTGCTCCCGCGCGTGACCTCGGCCTTTCTCGACG
AACGCTTCGACCGTGAAATCATGTCGGAAATGGGTCGGCTCGGACTGCTCGGCGCGACGATCGATCCCGAATATGGCGGC
GCGGGGCTCAATTATGTCTCCTACGGGCTGATCGCGCGCGAGGTCGAGCGCATCGATTCGGGATACCGCTCAGCCTGTTC
GGTGCAGAGCAGCCTCGTGATCCATCCGATCAACGCCTATGGCAGCGAGGAACAGAAGCGCAACTTCCTGCCCGGACTGA
CTTCGGGCGAACTCGTCGGCTGCTTCGGCCTGACCGAACCCGACGCCGGCAGCGATCCCGCCGGGATGCGCACGCGCGCC
GAAAAGATCGAAGGCGGCTATCGCCTCAAGGGCGCGAAGATGTGGATCACCAATTCGCCGATCGCCGACGTCTTTGTCGT
GTGGGCGAAGTCCGACGCGCACGGCGGCGCGATCCGCGGCTTCCTGCTCGAAAAGGGGATGAAGGGCCTGTCGGCGCCGA
AGATCGAGGGCAAGGTGTCCTTGCGCGCGTCGGTCACCGGCGAGATCGTCATGGACGGCGTCGAGGTCGGCGAGGATGCG
CTTCTGCCGCACGTATCGGGGCTCAAGGGGCCATTCGGTTGCCTCAACCGCGCGCGCTATGGCATCGGCTGGGGCGCGAT
GGGCGCGGCGGAGTTCTGCTATGAAGCGGCGCGCAATTATACGCTCGAGCGCAAGCAGTTCGGGCGCCCGCTCGCCGCGA
ACCAGATCGTGCAGTTGAAGCTCGCCAACATGCTCACCGAGATCGCGCTTGGCACCCAGGCGGCGCTGCGCGTCGGCCGG
CTGATCGACGAAGGGCATCTGGCCCCCGACATGATCAGTTTCCTGAAACGCAACAATTGCGGCAAGGCGCTCGACATCGC
GCGCACCGCGCGCGACATGCACGGCGGCAACGGCATTTCGGCCGATTATCATGTCATCCGCCACGCGGTGAATCTCGAAA
CGGTGAACACCTATGAAGGGACGCACGACGTCCACGCGCTGATCCTTGGCCGGGCGATCACGGGCATTTCGGCCTTTGCC
TGA

Upstream 100 bases:

>100_bases
GCGACAGCCCTGCTGCCGCGCTGGCCGAAAAAACGGCCGCCCCGACCCCGTAGCGCGCATTCCTTCAAGGGGTGCCGCCG
TCTTTAGGAAAGCCCTTTCC

Downstream 100 bases:

>100_bases
TCCGAAACCGCTGGAGGGCATCCGCGTCGTCGAGCTGGCGCGGGTGCTCGCGGGCCCGTGGTGCGGGCAATTGCTCGCCG
ATCTGGGAGCCGAGGTGGTC

Product: acyl-CoA dehydrogenase-like protein

Products: crotonoyl-CoA; CO2; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MALADPQRIEALDPLDPLALDAQLSEEERMIRDAARSYAEGELLPRVTSAFLDERFDREIMSEMGRLGLLGATIDPEYGG
AGLNYVSYGLIAREVERIDSGYRSACSVQSSLVIHPINAYGSEEQKRNFLPGLTSGELVGCFGLTEPDAGSDPAGMRTRA
EKIEGGYRLKGAKMWITNSPIADVFVVWAKSDAHGGAIRGFLLEKGMKGLSAPKIEGKVSLRASVTGEIVMDGVEVGEDA
LLPHVSGLKGPFGCLNRARYGIGWGAMGAAEFCYEAARNYTLERKQFGRPLAANQIVQLKLANMLTEIALGTQAALRVGR
LIDEGHLAPDMISFLKRNNCGKALDIARTARDMHGGNGISADYHVIRHAVNLETVNTYEGTHDVHALILGRAITGISAFA

Sequences:

>Translated_400_residues
MALADPQRIEALDPLDPLALDAQLSEEERMIRDAARSYAEGELLPRVTSAFLDERFDREIMSEMGRLGLLGATIDPEYGG
AGLNYVSYGLIAREVERIDSGYRSACSVQSSLVIHPINAYGSEEQKRNFLPGLTSGELVGCFGLTEPDAGSDPAGMRTRA
EKIEGGYRLKGAKMWITNSPIADVFVVWAKSDAHGGAIRGFLLEKGMKGLSAPKIEGKVSLRASVTGEIVMDGVEVGEDA
LLPHVSGLKGPFGCLNRARYGIGWGAMGAAEFCYEAARNYTLERKQFGRPLAANQIVQLKLANMLTEIALGTQAALRVGR
LIDEGHLAPDMISFLKRNNCGKALDIARTARDMHGGNGISADYHVIRHAVNLETVNTYEGTHDVHALILGRAITGISAFA
>Mature_399_residues
ALADPQRIEALDPLDPLALDAQLSEEERMIRDAARSYAEGELLPRVTSAFLDERFDREIMSEMGRLGLLGATIDPEYGGA
GLNYVSYGLIAREVERIDSGYRSACSVQSSLVIHPINAYGSEEQKRNFLPGLTSGELVGCFGLTEPDAGSDPAGMRTRAE
KIEGGYRLKGAKMWITNSPIADVFVVWAKSDAHGGAIRGFLLEKGMKGLSAPKIEGKVSLRASVTGEIVMDGVEVGEDAL
LPHVSGLKGPFGCLNRARYGIGWGAMGAAEFCYEAARNYTLERKQFGRPLAANQIVQLKLANMLTEIALGTQAALRVGRL
IDEGHLAPDMISFLKRNNCGKALDIARTARDMHGGNGISADYHVIRHAVNLETVNTYEGTHDVHALILGRAITGISAFA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4503943, Length=400, Percent_Identity=65, Blast_Score=523, Evalue=1e-149,
Organism=Homo sapiens, GI7669494, Length=379, Percent_Identity=63.8522427440633, Blast_Score=486, Evalue=1e-137,
Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=31.0991957104558, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI226958412, Length=395, Percent_Identity=32.1518987341772, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI4557233, Length=370, Percent_Identity=31.3513513513514, Blast_Score=175, Evalue=7e-44,
Organism=Homo sapiens, GI226958414, Length=348, Percent_Identity=32.4712643678161, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI4501857, Length=378, Percent_Identity=29.8941798941799, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI187960098, Length=380, Percent_Identity=29.7368421052632, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI4557231, Length=380, Percent_Identity=29.7368421052632, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI7656849, Length=385, Percent_Identity=29.6103896103896, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI4557235, Length=339, Percent_Identity=31.2684365781711, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI76496475, Length=336, Percent_Identity=31.547619047619, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI21361497, Length=352, Percent_Identity=29.8295454545455, Blast_Score=135, Evalue=5e-32,
Organism=Escherichia coli, GI87081958, Length=389, Percent_Identity=24.9357326478149, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786223, Length=344, Percent_Identity=23.2558139534884, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17534353, Length=387, Percent_Identity=62.015503875969, Blast_Score=503, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI17538396, Length=377, Percent_Identity=33.9522546419098, Blast_Score=188, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17569725, Length=380, Percent_Identity=30.2631578947368, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17508101, Length=380, Percent_Identity=29.4736842105263, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17534899, Length=380, Percent_Identity=28.1578947368421, Blast_Score=147, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI17506239, Length=373, Percent_Identity=28.1501340482574, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17570075, Length=380, Percent_Identity=28.9473684210526, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI71990804, Length=261, Percent_Identity=32.9501915708812, Blast_Score=141, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI71985184, Length=358, Percent_Identity=29.608938547486, Blast_Score=138, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI71982178, Length=272, Percent_Identity=30.1470588235294, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=34.1991341991342, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71985192, Length=267, Percent_Identity=31.4606741573034, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17533517, Length=389, Percent_Identity=25.1928020565553, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17551932, Length=250, Percent_Identity=24.8, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19920834, Length=389, Percent_Identity=63.7532133676092, Blast_Score=492, Evalue=1e-139,
Organism=Drosophila melanogaster, GI24666513, Length=379, Percent_Identity=30.8707124010554, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24646207, Length=381, Percent_Identity=32.0209973753281, Blast_Score=174, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24660351, Length=391, Percent_Identity=31.2020460358056, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI21356377, Length=380, Percent_Identity=30, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI21355753, Length=380, Percent_Identity=29.4736842105263, Blast_Score=161, Evalue=8e-40,
Organism=Drosophila melanogaster, GI281363737, Length=403, Percent_Identity=28.287841191067, Blast_Score=135, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.7

Molecular weight: Translated: 43119; Mature: 42988

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALADPQRIEALDPLDPLALDAQLSEEERMIRDAARSYAEGELLPRVTSAFLDERFDREI
CCCCCCHHHCCCCCCCCCEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
MSEMGRLGLLGATIDPEYGGAGLNYVSYGLIAREVERIDSGYRSACSVQSSLVIHPINAY
HHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
GSEEQKRNFLPGLTSGELVGCFGLTEPDAGSDPAGMRTRAEKIEGGYRLKGAKMWITNSP
CCHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCEEEECEEEEEECCC
IADVFVVWAKSDAHGGAIRGFLLEKGMKGLSAPKIEGKVSLRASVTGEIVMDGVEVGEDA
CCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCHHEECCHHCCCHH
LLPHVSGLKGPFGCLNRARYGIGWGAMGAAEFCYEAARNYTLERKQFGRPLAANQIVQLK
HCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHH
LANMLTEIALGTQAALRVGRLIDEGHLAPDMISFLKRNNCGKALDIARTARDMHGGNGIS
HHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCC
ADYHVIRHAVNLETVNTYEGTHDVHALILGRAITGISAFA
HHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALADPQRIEALDPLDPLALDAQLSEEERMIRDAARSYAEGELLPRVTSAFLDERFDREI
CCCCCHHHCCCCCCCCCEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
MSEMGRLGLLGATIDPEYGGAGLNYVSYGLIAREVERIDSGYRSACSVQSSLVIHPINAY
HHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
GSEEQKRNFLPGLTSGELVGCFGLTEPDAGSDPAGMRTRAEKIEGGYRLKGAKMWITNSP
CCHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCEEEECEEEEEECCC
IADVFVVWAKSDAHGGAIRGFLLEKGMKGLSAPKIEGKVSLRASVTGEIVMDGVEVGEDA
CCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCHHEECCHHCCCHH
LLPHVSGLKGPFGCLNRARYGIGWGAMGAAEFCYEAARNYTLERKQFGRPLAANQIVQLK
HCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHH
LANMLTEIALGTQAALRVGRLIDEGHLAPDMISFLKRNNCGKALDIARTARDMHGGNGIS
HHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCC
ADYHVIRHAVNLETVNTYEGTHDVHALILGRAITGISAFA
HHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutaryl-CoA; acceptor

Specific reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]