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The map label for this gene is cirA [H]

Identifier: 103487913

GI number: 103487913

Start: 2571241

End: 2573355

Strand: Reverse

Name: cirA [H]

Synonym: Sala_2433

Alternate gene names: 103487913

Gene position: 2573355-2571241 (Counterclockwise)

Preceding gene: 103487914

Following gene: 103487904

Centisome position: 76.93

GC content: 57.97

Gene sequence:

>2115_bases
ATGAACAAATTATACTGTTATTCGTCGACGAAGCGCGCAATGCAGCGAAGCTCGATGGCGGCGATTGCGGTGGCGGTCGC
GTTTCCCGCGCAGGCTCAGGAAGCCCAGTCGGACGGCCTCGCCGAGATCATCGTAACGGCGGAGAAGCGCGAGGAAAATC
TGCAGTCCGTTCCCGTCTCGGTGACAGCGATGACCGGCGAGGCGCTTACGGCAACGGGCATATCAAACGTCGAAGACCTC
CAATTTTTTGTGCCGGGCGTGTCGATCACCAACGATTCCATGGCGATCATCAATATTCGTGGAATTGGCACCTCGGCGTT
CGGCGTTGCGACCGACCCCAGCACGACAGTCCATTATGACGGCGTCTACATCTCGCGCCCGACCACAAACTATCAGGATT
TGTTCGACGTCGAACGCATCGAGGTGCTGCGCGGACCGCAAGGCGTTCTCTTCGGTCGCAACTCCGCCGGCGGCACACTC
AACATCATTTCCAAAATGCCTACGGAGGATTTGACTGGCGCGCTGGGACTCACCGTCGGAAATTACGAGAAGCGCTCGCT
GAGCGGCACGATTTCTGGACCGCTTGGAGCGGGCGTCCGAGGCCGCCTCACCTTGCTTGCCAACCAGCGCGACGGCATCT
ACCGCGACGTCGTCTCGGGACGGCGATACCAAAACGAAGATAATCTCGCTGGACGACTGACGCTTGCGATTGACGCGAGC
GACCGTCTTGAGATCGTGTTGCGGGCGGATGCCAGCCGTGATCGCGAGACCGGCGCGCGGTCTGTTCGGCCCTTTTATCC
GCAAGGCTTCGTCGATGCGGGGGCGACGATCCCGGCCAATGACAAAGAGGCCGCACTCGACCGCCTGCCGCGTTACGATG
TCGATGCCTGGGGCGTGTCCTCGACCATGAACTGGGACGGCGGCCCGGTCACGCTCCGCTCGATTACGGCGCTGCGCAAG
AGCAAGGTCGTCCAGGCGCTCGACGTTGACTCGACTGACCTCTTCCTCCGCGATATCGAATTTTACGAACGTTCCCGCAG
TTTCACGCAAGAGTTCCAACTTCTCAACAACGATGCGGACAAGCTGCGCTGGATCGTCGGAGCATTCTATCTGAATGAAA
AGGGCAACGACGAAATACGGATCATCGAACCGGGTCGTCGGCTCGCGATCCCGGAAAACAATACGACGAATGCATTCGCG
CTCTTCGGACAAGCAAGCTACGAACTCATCGACCGCCTGCGATTGACCGGAGGGCTTCGATACTCATACGAAAAAAAGGA
TTTCGGATATCGTGTCCTGCTGAACGGAAATCAGGTCGATGCCGGTCAGCCCAAATCATCCTGGACCGCCTGGACTCCGA
AAATTGGGATCGATTACGACCTTGCCGATGACGTCATGGCTTATGCGTCGGCAACCCGCGGGTTCAAATCGGGTGGATTC
CAGCTGGGAGACGGGCGGCCTTTCCTCCCGGAGTATGTCTGGAGCTACGAAGTCGGCTTGAAGTCGACGCTCCTCGATCG
CCGGCTTCGAGCTAATTTTTCGGCCTTCTATTATGATTACACCAATCTTCAGGTGGTCGAGTATAATAATGGCGTTGCCA
GTACCACCAACGCCGGCAAGGCGACGATCAAGGGCGTTGAAGCGGAACTGATGGCACGGCCGTTCGATCGCCTGACGCTT
ACATCCACGATCGCTTATCTCGATGCGCGCTACGATGTCTATTTTGACGACGTCGGCGCAAGCCTCAAGGGCAAGCGGCT
GCCGAACGCGCCGAAGTGGAACATCACTCTCGGCGGAGAATATAAGGCCTCCCTGGGCGGCGGAATGCTGACATTACGGA
CCGATATCTCCTGGCGCGACAGCATCTTTTTCAAGCCCAGCAACAATCCGCTTTTTTCCGGAAACGCCACGACCCTTATA
AATGGGCGTGTCGCATGGCAGCCGGCGAGCGAAGCGTGGGAAATTGCGCTTTATGGCCGAAATCTCACCAACGAGCGCTA
TGTGAGCTATAGTACGATCGGGACGGACGCGACGGGTGTCTCGAACCCTACTCTTCCGCTCTACATCTACGGCGAGCCGC
GCCAGTACGGATTGCAGCTGCGCTACTTTTTCTGA

Upstream 100 bases:

>100_bases
GTAAGCAGCGGTTTCCGGGCATGCATGTTTTTGTCCTCGACTTCCCCGAAACTCATTTGGGCTGCGCGAAAGGGCAGTTC
TTCGAAACAGGGGAAGCATA

Downstream 100 bases:

>100_bases
GGTTCCTCGTCCTGCGAGGTCCCCCGGCGACTCCCCTACGGTCGTCGGTCCCCCTGGGCGCTTGCGCCCGGGGGGAATAC
TTCCTCTGAACGCAGGACAT

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 704; Mature: 704

Protein sequence:

>704_residues
MNKLYCYSSTKRAMQRSSMAAIAVAVAFPAQAQEAQSDGLAEIIVTAEKREENLQSVPVSVTAMTGEALTATGISNVEDL
QFFVPGVSITNDSMAIINIRGIGTSAFGVATDPSTTVHYDGVYISRPTTNYQDLFDVERIEVLRGPQGVLFGRNSAGGTL
NIISKMPTEDLTGALGLTVGNYEKRSLSGTISGPLGAGVRGRLTLLANQRDGIYRDVVSGRRYQNEDNLAGRLTLAIDAS
DRLEIVLRADASRDRETGARSVRPFYPQGFVDAGATIPANDKEAALDRLPRYDVDAWGVSSTMNWDGGPVTLRSITALRK
SKVVQALDVDSTDLFLRDIEFYERSRSFTQEFQLLNNDADKLRWIVGAFYLNEKGNDEIRIIEPGRRLAIPENNTTNAFA
LFGQASYELIDRLRLTGGLRYSYEKKDFGYRVLLNGNQVDAGQPKSSWTAWTPKIGIDYDLADDVMAYASATRGFKSGGF
QLGDGRPFLPEYVWSYEVGLKSTLLDRRLRANFSAFYYDYTNLQVVEYNNGVASTTNAGKATIKGVEAELMARPFDRLTL
TSTIAYLDARYDVYFDDVGASLKGKRLPNAPKWNITLGGEYKASLGGGMLTLRTDISWRDSIFFKPSNNPLFSGNATTLI
NGRVAWQPASEAWEIALYGRNLTNERYVSYSTIGTDATGVSNPTLPLYIYGEPRQYGLQLRYFF

Sequences:

>Translated_704_residues
MNKLYCYSSTKRAMQRSSMAAIAVAVAFPAQAQEAQSDGLAEIIVTAEKREENLQSVPVSVTAMTGEALTATGISNVEDL
QFFVPGVSITNDSMAIINIRGIGTSAFGVATDPSTTVHYDGVYISRPTTNYQDLFDVERIEVLRGPQGVLFGRNSAGGTL
NIISKMPTEDLTGALGLTVGNYEKRSLSGTISGPLGAGVRGRLTLLANQRDGIYRDVVSGRRYQNEDNLAGRLTLAIDAS
DRLEIVLRADASRDRETGARSVRPFYPQGFVDAGATIPANDKEAALDRLPRYDVDAWGVSSTMNWDGGPVTLRSITALRK
SKVVQALDVDSTDLFLRDIEFYERSRSFTQEFQLLNNDADKLRWIVGAFYLNEKGNDEIRIIEPGRRLAIPENNTTNAFA
LFGQASYELIDRLRLTGGLRYSYEKKDFGYRVLLNGNQVDAGQPKSSWTAWTPKIGIDYDLADDVMAYASATRGFKSGGF
QLGDGRPFLPEYVWSYEVGLKSTLLDRRLRANFSAFYYDYTNLQVVEYNNGVASTTNAGKATIKGVEAELMARPFDRLTL
TSTIAYLDARYDVYFDDVGASLKGKRLPNAPKWNITLGGEYKASLGGGMLTLRTDISWRDSIFFKPSNNPLFSGNATTLI
NGRVAWQPASEAWEIALYGRNLTNERYVSYSTIGTDATGVSNPTLPLYIYGEPRQYGLQLRYFF
>Mature_704_residues
MNKLYCYSSTKRAMQRSSMAAIAVAVAFPAQAQEAQSDGLAEIIVTAEKREENLQSVPVSVTAMTGEALTATGISNVEDL
QFFVPGVSITNDSMAIINIRGIGTSAFGVATDPSTTVHYDGVYISRPTTNYQDLFDVERIEVLRGPQGVLFGRNSAGGTL
NIISKMPTEDLTGALGLTVGNYEKRSLSGTISGPLGAGVRGRLTLLANQRDGIYRDVVSGRRYQNEDNLAGRLTLAIDAS
DRLEIVLRADASRDRETGARSVRPFYPQGFVDAGATIPANDKEAALDRLPRYDVDAWGVSSTMNWDGGPVTLRSITALRK
SKVVQALDVDSTDLFLRDIEFYERSRSFTQEFQLLNNDADKLRWIVGAFYLNEKGNDEIRIIEPGRRLAIPENNTTNAFA
LFGQASYELIDRLRLTGGLRYSYEKKDFGYRVLLNGNQVDAGQPKSSWTAWTPKIGIDYDLADDVMAYASATRGFKSGGF
QLGDGRPFLPEYVWSYEVGLKSTLLDRRLRANFSAFYYDYTNLQVVEYNNGVASTTNAGKATIKGVEAELMARPFDRLTL
TSTIAYLDARYDVYFDDVGASLKGKRLPNAPKWNITLGGEYKASLGGGMLTLRTDISWRDSIFFKPSNNPLFSGNATTLI
NGRVAWQPASEAWEIALYGRNLTNERYVSYSTIGTDATGVSNPTLPLYIYGEPRQYGLQLRYFF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=195, Percent_Identity=30.7692307692308, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 77691; Mature: 77691

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLYCYSSTKRAMQRSSMAAIAVAVAFPAQAQEAQSDGLAEIIVTAEKREENLQSVPVS
CCEEEEECCHHHHHHHHHHEEEEEEEECCCHHHHHHCCCCEEEEEEEHHHHCCHHHCCEE
VTAMTGEALTATGISNVEDLQFFVPGVSITNDSMAIINIRGIGTSAFGVATDPSTTVHYD
EEEECCCEEEECCCCCCCEEEEEECCEEECCCCEEEEEEEECCCCCCEEECCCCCEEEEC
GVYISRPTTNYQDLFDVERIEVLRGPQGVLFGRNSAGGTLNIISKMPTEDLTGALGLTVG
CEEEECCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCHHHCCEEEEEEC
NYEKRSLSGTISGPLGAGVRGRLTLLANQRDGIYRDVVSGRRYQNEDNLAGRLTLAIDAS
CCCCCCCCEEECCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCCCCCCCCEEEEEEEECC
DRLEIVLRADASRDRETGARSVRPFYPQGFVDAGATIPANDKEAALDRLPRYDVDAWGVS
CCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCC
STMNWDGGPVTLRSITALRKSKVVQALDVDSTDLFLRDIEFYERSRSFTQEFQLLNNDAD
CCCCCCCCCEEHHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KLRWIVGAFYLNEKGNDEIRIIEPGRRLAIPENNTTNAFALFGQASYELIDRLRLTGGLR
HHEEEEEEEEECCCCCCEEEEECCCCEEECCCCCCCCEEEEECCCHHHHHHHHHHCCCCE
YSYEKKDFGYRVLLNGNQVDAGQPKSSWTAWTPKIGIDYDLADDVMAYASATRGFKSGGF
EEEECCCCCEEEEEECCEECCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCE
QLGDGRPFLPEYVWSYEVGLKSTLLDRRLRANFSAFYYDYTNLQVVEYNNGVASTTNAGK
ECCCCCCCCCHHHEEEECCHHHHHHHHHHHCCCEEEEEEECCEEEEEECCCCCCCCCCCC
ATIKGVEAELMARPFDRLTLTSTIAYLDARYDVYFDDVGASLKGKRLPNAPKWNITLGGE
EEEECCHHHHHHCCCCCEEHHHHEEEEECEEEEEEECCCCCCCCCCCCCCCEEEEEECCC
YKASLGGGMLTLRTDISWRDSIFFKPSNNPLFSGNATTLINGRVAWQPASEAWEIALYGR
EEECCCCCEEEEEECCCCCCEEEECCCCCEEECCCCEEEEECEEEECCCCCCEEEEEECC
NLTNERYVSYSTIGTDATGVSNPTLPLYIYGEPRQYGLQLRYFF
CCCCCEEEEEEECCCCCCCCCCCCEEEEEEECCHHHCEEEEEEC
>Mature Secondary Structure
MNKLYCYSSTKRAMQRSSMAAIAVAVAFPAQAQEAQSDGLAEIIVTAEKREENLQSVPVS
CCEEEEECCHHHHHHHHHHEEEEEEEECCCHHHHHHCCCCEEEEEEEHHHHCCHHHCCEE
VTAMTGEALTATGISNVEDLQFFVPGVSITNDSMAIINIRGIGTSAFGVATDPSTTVHYD
EEEECCCEEEECCCCCCCEEEEEECCEEECCCCEEEEEEEECCCCCCEEECCCCCEEEEC
GVYISRPTTNYQDLFDVERIEVLRGPQGVLFGRNSAGGTLNIISKMPTEDLTGALGLTVG
CEEEECCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCHHHCCEEEEEEC
NYEKRSLSGTISGPLGAGVRGRLTLLANQRDGIYRDVVSGRRYQNEDNLAGRLTLAIDAS
CCCCCCCCEEECCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCCCCCCCCEEEEEEEECC
DRLEIVLRADASRDRETGARSVRPFYPQGFVDAGATIPANDKEAALDRLPRYDVDAWGVS
CCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCC
STMNWDGGPVTLRSITALRKSKVVQALDVDSTDLFLRDIEFYERSRSFTQEFQLLNNDAD
CCCCCCCCCEEHHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KLRWIVGAFYLNEKGNDEIRIIEPGRRLAIPENNTTNAFALFGQASYELIDRLRLTGGLR
HHEEEEEEEEECCCCCCEEEEECCCCEEECCCCCCCCEEEEECCCHHHHHHHHHHCCCCE
YSYEKKDFGYRVLLNGNQVDAGQPKSSWTAWTPKIGIDYDLADDVMAYASATRGFKSGGF
EEEECCCCCEEEEEECCEECCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCE
QLGDGRPFLPEYVWSYEVGLKSTLLDRRLRANFSAFYYDYTNLQVVEYNNGVASTTNAGK
ECCCCCCCCCHHHEEEECCHHHHHHHHHHHCCCEEEEEEECCEEEEEECCCCCCCCCCCC
ATIKGVEAELMARPFDRLTLTSTIAYLDARYDVYFDDVGASLKGKRLPNAPKWNITLGGE
EEEECCHHHHHHCCCCCEEHHHHEEEEECEEEEEEECCCCCCCCCCCCCCCEEEEEECCC
YKASLGGGMLTLRTDISWRDSIFFKPSNNPLFSGNATTLINGRVAWQPASEAWEIALYGR
EEECCCCCEEEEEECCCCCCEEEECCCCCEEECCCCEEEEECEEEECCCCCCEEEEEECC
NLTNERYVSYSTIGTDATGVSNPTLPLYIYGEPRQYGLQLRYFF
CCCCCEEEEEEECCCCCCCCCCCCEEEEEEECCHHHCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]