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The map label for this gene is rnd [H]

Identifier: 103487824

GI number: 103487824

Start: 2470343

End: 2470960

Strand: Reverse

Name: rnd [H]

Synonym: Sala_2343

Alternate gene names: 103487824

Gene position: 2470960-2470343 (Counterclockwise)

Preceding gene: 103487826

Following gene: 103487823

Centisome position: 73.87

GC content: 65.7

Gene sequence:

>618_bases
ATGAGCGTATATTTCCACGAAGAAGACCTGCCCGAAGATGTGCTGGGGCCTGGCGCGGTCGCGGTCGATACCGAAACCAT
GGGGCTCAATCCGCTGCGCGACCGGCTGTGCCTCGTCCAGATCAGCGACGGGTCGGGCGACGAGCATCTGGTTCGTTTCA
GGCCCGGCAGCAGCTACGACGCGCCGGTGCTGAAGGCGATCCTCGCCGACCCGGAGCGGCTGAAACTCTTTCATTTCGCG
CGTTTCGACATCGCCGCGTTGCAGCAGGCACTCGGCGTCGTGACGACGCCCGTCTATTGCACCAAGATCGCCTCGAAGCT
GGTGCGCACCTATACCGACCGCCATGGCCTCAAGGAACTGGTGCGCGAGCTGCTGGGGCAGGAGGTGTCGAAGCAGCAGC
AGTCGAGCGACTGGGGCGCCGCCGAACTCAGCGAGGCGCAGCGCGACTATGCCGCGAGCGACGTGCGGTTCCTGCACGCG
ATGAAGGAGATCCTCGACGCGCGGCTGGCGCGCGAGGGGCGCACCGAATTGGCGCAGGCCTGTTTCGATTTCCTGCCGAC
GCGCGCGGCGCTCGACCTCGCGGGATGGCCCGAGGTCGATATTTTCGCGCACAGTTGA

Upstream 100 bases:

>100_bases
TTCGGGAATATCATACAGATTACCGCGGCCCCGGCCCGGCGTGGCAGGCCGGCGAAAACCAGTCATTGAGCGGCGCGGCC
GCTTGGCCTAAGGCGGCGGG

Downstream 100 bases:

>100_bases
GGATCGATTCGCAAGCGATGTCCGAACGCGCCGACCTTGACCGCACGATGCGCCAGATGTGGGCGCGCAGCGGATCGAGC
CACGACCGGGTGGTGCGCGT

Product: 3'-5' exonuclease

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MSVYFHEEDLPEDVLGPGAVAVDTETMGLNPLRDRLCLVQISDGSGDEHLVRFRPGSSYDAPVLKAILADPERLKLFHFA
RFDIAALQQALGVVTTPVYCTKIASKLVRTYTDRHGLKELVRELLGQEVSKQQQSSDWGAAELSEAQRDYAASDVRFLHA
MKEILDARLAREGRTELAQACFDFLPTRAALDLAGWPEVDIFAHS

Sequences:

>Translated_205_residues
MSVYFHEEDLPEDVLGPGAVAVDTETMGLNPLRDRLCLVQISDGSGDEHLVRFRPGSSYDAPVLKAILADPERLKLFHFA
RFDIAALQQALGVVTTPVYCTKIASKLVRTYTDRHGLKELVRELLGQEVSKQQQSSDWGAAELSEAQRDYAASDVRFLHA
MKEILDARLAREGRTELAQACFDFLPTRAALDLAGWPEVDIFAHS
>Mature_204_residues
SVYFHEEDLPEDVLGPGAVAVDTETMGLNPLRDRLCLVQISDGSGDEHLVRFRPGSSYDAPVLKAILADPERLKLFHFAR
FDIAALQQALGVVTTPVYCTKIASKLVRTYTDRHGLKELVRELLGQEVSKQQQSSDWGAAELSEAQRDYAASDVRFLHAM
KEILDARLAREGRTELAQACFDFLPTRAALDLAGWPEVDIFAHS

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Escherichia coli, GI1788105, Length=140, Percent_Identity=32.8571428571429, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 22785; Mature: 22654

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVYFHEEDLPEDVLGPGAVAVDTETMGLNPLRDRLCLVQISDGSGDEHLVRFRPGSSYD
CCEEECCCCCCHHHCCCCCEEECCCCCCCCHHHCCEEEEEECCCCCCCCEEEECCCCCCC
APVLKAILADPERLKLFHFARFDIAALQQALGVVTTPVYCTKIASKLVRTYTDRHGLKEL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
VRELLGQEVSKQQQSSDWGAAELSEAQRDYAASDVRFLHAMKEILDARLAREGRTELAQA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
CFDFLPTRAALDLAGWPEVDIFAHS
HHHHHCHHHHHCCCCCCCCEEEECC
>Mature Secondary Structure 
SVYFHEEDLPEDVLGPGAVAVDTETMGLNPLRDRLCLVQISDGSGDEHLVRFRPGSSYD
CEEECCCCCCHHHCCCCCEEECCCCCCCCHHHCCEEEEEECCCCCCCCEEEECCCCCCC
APVLKAILADPERLKLFHFARFDIAALQQALGVVTTPVYCTKIASKLVRTYTDRHGLKEL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
VRELLGQEVSKQQQSSDWGAAELSEAQRDYAASDVRFLHAMKEILDARLAREGRTELAQA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
CFDFLPTRAALDLAGWPEVDIFAHS
HHHHHCHHHHHCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]