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The map label for this gene is hflK [H]

Identifier: 103487730

GI number: 103487730

Start: 2362137

End: 2363297

Strand: Reverse

Name: hflK [H]

Synonym: Sala_2249

Alternate gene names: 103487730

Gene position: 2363297-2362137 (Counterclockwise)

Preceding gene: 103487738

Following gene: 103487729

Centisome position: 70.65

GC content: 66.49

Gene sequence:

>1161_bases
ATGAGCGACCAGATTGAAGGCAGCATGGGACGCCGCACCCTCCGGGGATTGCGGCAATTTTTCGATTCGATCAGCCAGAT
GGCCAACAGCCCGTGGGGCAATGGCCCGGGCAAGGGCGAGGATGACGACGGCAAGGGCGGCGACGGCAAGCGGCCGGGGC
CGCGCAACCCCTGGGTCACGCCCGACCCGGCCGACCAGCGCCGCGGGGCAAAACCGCGCGGCCCGTCGGCGCTCGACGAA
CTGCTGCGCAAGGGACGTGGCGGTTTCGGCGGCGGCGGTTCGGGCGGCGGCGGGTTCGACTTCGCCGATTCGGGACGAAT
ATGGAAATGGGGGATCGTCGCGGTTCTCGCGGTCTGGCTCTTCTTCTCCTCCTTCCACATCGTGCCGCCCGAAAAGGAGG
GCGTGGTCACCCGGCTCGGCAGCTATGCGCGCACCGTCGGTCCCGGCGTCAAATTGACCTGGCCGGCGCCGATCGAGCGC
ATCCGCATGGAGGACGTCCGCGCGATCCGTACGATGGCGATCGGATCGCCCAAAGCGACCGACGAGAACTTCGTGCTGAC
GCGCGACCAGAGCATCGTCGATCTGGCCTATGAGGTCCGCTGGTCGGTGCGCGCGCCCGAGCTGTTCTTTTTCCAGATCG
CCAATCCCGAGGACACGATCCGCGAGGTCGCCGAAAGCGCGATGCGCGCGACGGTCGCCAATTTCGACCTTGTGCAGGCG
ATCGGCCCCGGCCGCGTCGAGATCGAGGCGCAGGTACAGAGCCGGATGCAGGCGCTGCTCGACGAATATCGCGCCGGCGT
GACGATTCAGGGCATCGCGATCCGTCAGGCGGACCCGCCAAGCCAGGTCGACGAGGCGTTCAAGGAAGTCACCGCAGCGC
GGCAGGAACGCGAAGCGGCGATCAACCTGGCCCGCGCCTATCAGCAGCAGGTGCTCGAACGCGCGCGCGGCGATACGTCC
GCGTTCGACCAGATTTACGAACAATATCGGCTGGCGCCGGAGGTGACCCGCCAGCGGCTTTATTATGAAACGATGGAGGC
CGTGTTGTCGAACGTCGACAAGACGATTGTCGAAGCGCGCGGGGTGACCCCCTATCTGCCGCTCAACGAGGTCCAGAGAC
GACTGCGCGCGCCCGAAGCCGTGACAAAGGGAGGCGAATGA

Upstream 100 bases:

>100_bases
TCGGTCATGTCTGCGCCGAAATAGGGCCGCCGACGCGCTTTGCCAGCCATTTTCGCGCGCACCCCCTGTTAATCGCGCCC
GCCGCCCCTATAAAAGCAAT

Downstream 100 bases:

>100_bases
TGTTCGCGCCGCTTTTCCGCAATCCCGTGCGCCTGCTGGTCGGCATCGTCGCCCTGCTGGTGCTGTTGTCGATGACGGTG
TCGATCGTGCCGGAGGACCG

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MSDQIEGSMGRRTLRGLRQFFDSISQMANSPWGNGPGKGEDDDGKGGDGKRPGPRNPWVTPDPADQRRGAKPRGPSALDE
LLRKGRGGFGGGGSGGGGFDFADSGRIWKWGIVAVLAVWLFFSSFHIVPPEKEGVVTRLGSYARTVGPGVKLTWPAPIER
IRMEDVRAIRTMAIGSPKATDENFVLTRDQSIVDLAYEVRWSVRAPELFFFQIANPEDTIREVAESAMRATVANFDLVQA
IGPGRVEIEAQVQSRMQALLDEYRAGVTIQGIAIRQADPPSQVDEAFKEVTAARQEREAAINLARAYQQQVLERARGDTS
AFDQIYEQYRLAPEVTRQRLYYETMEAVLSNVDKTIVEARGVTPYLPLNEVQRRLRAPEAVTKGGE

Sequences:

>Translated_386_residues
MSDQIEGSMGRRTLRGLRQFFDSISQMANSPWGNGPGKGEDDDGKGGDGKRPGPRNPWVTPDPADQRRGAKPRGPSALDE
LLRKGRGGFGGGGSGGGGFDFADSGRIWKWGIVAVLAVWLFFSSFHIVPPEKEGVVTRLGSYARTVGPGVKLTWPAPIER
IRMEDVRAIRTMAIGSPKATDENFVLTRDQSIVDLAYEVRWSVRAPELFFFQIANPEDTIREVAESAMRATVANFDLVQA
IGPGRVEIEAQVQSRMQALLDEYRAGVTIQGIAIRQADPPSQVDEAFKEVTAARQEREAAINLARAYQQQVLERARGDTS
AFDQIYEQYRLAPEVTRQRLYYETMEAVLSNVDKTIVEARGVTPYLPLNEVQRRLRAPEAVTKGGE
>Mature_385_residues
SDQIEGSMGRRTLRGLRQFFDSISQMANSPWGNGPGKGEDDDGKGGDGKRPGPRNPWVTPDPADQRRGAKPRGPSALDEL
LRKGRGGFGGGGSGGGGFDFADSGRIWKWGIVAVLAVWLFFSSFHIVPPEKEGVVTRLGSYARTVGPGVKLTWPAPIERI
RMEDVRAIRTMAIGSPKATDENFVLTRDQSIVDLAYEVRWSVRAPELFFFQIANPEDTIREVAESAMRATVANFDLVQAI
GPGRVEIEAQVQSRMQALLDEYRAGVTIQGIAIRQADPPSQVDEAFKEVTAARQEREAAINLARAYQQQVLERARGDTSA
FDQIYEQYRLAPEVTRQRLYYETMEAVLSNVDKTIVEARGVTPYLPLNEVQRRLRAPEAVTKGGE

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=287, Percent_Identity=30.3135888501742, Blast_Score=143, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 42623; Mature: 42491

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQIEGSMGRRTLRGLRQFFDSISQMANSPWGNGPGKGEDDDGKGGDGKRPGPRNPWVT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PDPADQRRGAKPRGPSALDELLRKGRGGFGGGGSGGGGFDFADSGRIWKWGIVAVLAVWL
CCCCHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHH
FFSSFHIVPPEKEGVVTRLGSYARTVGPGVKLTWPAPIERIRMEDVRAIRTMAIGSPKAT
HHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCC
DENFVLTRDQSIVDLAYEVRWSVRAPELFFFQIANPEDTIREVAESAMRATVANFDLVQA
CCCEEEECCCHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
IGPGRVEIEAQVQSRMQALLDEYRAGVTIQGIAIRQADPPSQVDEAFKEVTAARQEREAA
CCCCCEEEHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
INLARAYQQQVLERARGDTSAFDQIYEQYRLAPEVTRQRLYYETMEAVLSNVDKTIVEAR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GVTPYLPLNEVQRRLRAPEAVTKGGE
CCCCCCCHHHHHHHHCCCHHHCCCCC
>Mature Secondary Structure 
SDQIEGSMGRRTLRGLRQFFDSISQMANSPWGNGPGKGEDDDGKGGDGKRPGPRNPWVT
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PDPADQRRGAKPRGPSALDELLRKGRGGFGGGGSGGGGFDFADSGRIWKWGIVAVLAVWL
CCCCHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHH
FFSSFHIVPPEKEGVVTRLGSYARTVGPGVKLTWPAPIERIRMEDVRAIRTMAIGSPKAT
HHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCC
DENFVLTRDQSIVDLAYEVRWSVRAPELFFFQIANPEDTIREVAESAMRATVANFDLVQA
CCCEEEECCCHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
IGPGRVEIEAQVQSRMQALLDEYRAGVTIQGIAIRQADPPSQVDEAFKEVTAARQEREAA
CCCCCEEEHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
INLARAYQQQVLERARGDTSAFDQIYEQYRLAPEVTRQRLYYETMEAVLSNVDKTIVEAR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GVTPYLPLNEVQRRLRAPEAVTKGGE
CCCCCCCHHHHHHHHCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]