Click here to switch to the map view.

The map label for this gene is yciR [C]

Identifier: 103487670

GI number: 103487670

Start: 2300034

End: 2302223

Strand: Reverse

Name: yciR [C]

Synonym: Sala_2189

Alternate gene names: 103487670

Gene position: 2302223-2300034 (Counterclockwise)

Preceding gene: 103487672

Following gene: 103487669

Centisome position: 68.82

GC content: 66.39

Gene sequence:

>2190_bases
ATGGACATGCCATCGCGGACAGCGCCGGGCGAGCAGGGGGGGCACGGCGTCGACGAAGGCCCGCGCGGCTTTTTCGGTCG
AATCGGGTCGCGCGCGACCCGGCGCCGCGGCGACGCCGCAGCGAACCTGCAAACGCGCGAGGCGCTGCTTCTCCTCCAGA
ATTACGAAGAAAGCGGGCGCGGCTGGTTCTGGTCGACCGACGCCGATGGTCGGCTTACCTATATCACCGACGTGGTGGCG
CGGACGATGGGTCGCTCGGCGGCGGCGTTGCTGGGCACGCCCTTGACGGACCTCTTCCTGCCCGCCGACAGCCATGGCGA
GCGTCAGCGCACCTTGCGGTTCCTGCTCACGCGCCAGTCGGCGTTCGACGACCTGCCGCTGCGCGGCGCCTTCGAGGGCG
GTGATCGCTGGTGGGCGATATCGGGGCGGCCGCAATATGATGCGGACGGCCAGTTCACCGGCTATCGCGGCAGCGGCACC
GACATCACCGCGCAGCGCCGCTCGGCCGAGGATGCGTCGCGGCTTGCGCTCTATGATTCGCTCACCGGCCTCGCCAACCG
CTTCAACATCTCGAAAAAACTCGACGCGACGCTCGCCGCTTTTGCGCAGCAGCAGCGCTCGTGCGCGATCATGCTGCTCG
ACCTCGACCGCTTCAAGCAGGTCAACGACACGCTCGGTCATCCGGCCGGCGACGCGCTGCTTAAACAGGTCGCCGAACGG
CTGCTCAAGTTCGTCGGCGACAAGGAAATGGTCAGCCGATTGGGCGGCGACGAGTTCCAGATCATCCTTCCCGACATCGA
CGATCGCGGCAAGCTGGGCGACATGGCGGCCGACATCATCGCCAGCCTGTCGCAACCCTATTCGGTCGAGGGCAGCCGCT
GCATCATCGGCGCGTCGGTTGGCGTCGCGATCGCGCCGTTCGACGGGCAGAGCAGCGACGATCTGGTCCGCAACGCCGAC
CTTGCGCTCTATGCGGCGAAAGGCAATGGCTGCGGCCGCTTCGCCTTTTATTCGAGCGACCTGCACCAGGCGGCCGAAGA
CCGGCGCGCGCTGGAGGAAGATCTGCGCGACGCGCTGGCTCGCGGCGAGATTGCGCTCGCTTACCAGCCCGTCGTCAACG
CCAGGTCGAACATGGTGACCGGGGTCGAGGCGCTGATCCGCTGGACCCACCGCGACCGCGGGGCGATTTCGCCCGCACTG
TTCATCCCGATCGCCGAAGAAGCCAATCTTATCTGGCCGCTCGGCGAATGGGTGCTGAGGAAGGCATGCGAGGATGCCGC
GGGCTGGCCGGGCGAGATGCGCGTTGCGGTCAATGTCTCGCCGATCCAGTTCGCCAATCCCGAACTGCCCAAGGTCGTCG
CCAAGGCGCTGGCGGCCAGCGGGCTGTCGCCGGACCGGCTCGAACTGGAGATCACCGAAAGCGTGTTTCTGGGCGACACG
GCGGAAGCGAACCGGATGTTCAAGGCGCTGAAGGGGCTGGGCGTGCGGCTGGCGCTCGACGATTTCGGCACGGGCTATTC
GTCGCTTGCCTATCTGCAATCGGCGCCGTTCGACAAGATCAAGATCGACCAGAGTTTCGTGCGCGGGGCGACCGAACCGG
GGTCGCGCAACAGTGCGATCATTGCCGCGATCGTCGCGCTGGCCGAGGCGCTCGATATGGAAACGACCGCCGAGGGCATC
GAATCGCTCGACCAGCTCGATCTCGTCCGCAAGCTCAACGTCAGCCATGTCCAGGGCTATGTCTACTCGCGACCCGTGCC
TTGTGCCGACCTGGTCGGTCATACCGAGGCCGGCGTCTGGACGATCAAGCCGTCGGGTCCGGCGCGTCAGCGCAACGACC
GCTTGTCGCTGTTCCGCAAGGTTGGCGCGATCCACGACAATCACCGCTACGCCGTCGTCATCCGCAACCTGTCGGCGACC
GGGGCGTTCATCGAGGGCATTTTGGATGTGCCCGTCGGTACGCGCTTCGTGATCGATTTCGGCGAGGGACAGCTCGTCAC
CGCGACGGTGCGCCGGTCGATGAAGCACCAGCAGGGCATCGAGTTCGAACAGACGATGGTCAGCGACGGCAATGGCGGGC
TTTGCACGCGTCACCGCGTATCGCCCTATCTGATCGCCGCCGCGGCGCAGCAGACGAGCGCGCTGGCATTGCCGGCCTTT
ACGACGACGAGCGACTGGAAAGCCGCCTGA

Upstream 100 bases:

>100_bases
GTGAATCAGATATACAGCACGCCGCTCTCGATATTTACTCTCTGGCAAGGCATTGTCGGCATAGCGGCCGGACTGGGGAT
CAGACCGAAGAGTTTGCTGA

Downstream 100 bases:

>100_bases
CACAGGAACCCGACGCCTGGCGCTTCGTTCTGTCTTCGACCCGCTAAACGGACGGAGACGATAATGGCCGAAACCAGAAT
CTTTGCGCGGCTGAAAGCCG

Product: diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 729; Mature: 729

Protein sequence:

>729_residues
MDMPSRTAPGEQGGHGVDEGPRGFFGRIGSRATRRRGDAAANLQTREALLLLQNYEESGRGWFWSTDADGRLTYITDVVA
RTMGRSAAALLGTPLTDLFLPADSHGERQRTLRFLLTRQSAFDDLPLRGAFEGGDRWWAISGRPQYDADGQFTGYRGSGT
DITAQRRSAEDASRLALYDSLTGLANRFNISKKLDATLAAFAQQQRSCAIMLLDLDRFKQVNDTLGHPAGDALLKQVAER
LLKFVGDKEMVSRLGGDEFQIILPDIDDRGKLGDMAADIIASLSQPYSVEGSRCIIGASVGVAIAPFDGQSSDDLVRNAD
LALYAAKGNGCGRFAFYSSDLHQAAEDRRALEEDLRDALARGEIALAYQPVVNARSNMVTGVEALIRWTHRDRGAISPAL
FIPIAEEANLIWPLGEWVLRKACEDAAGWPGEMRVAVNVSPIQFANPELPKVVAKALAASGLSPDRLELEITESVFLGDT
AEANRMFKALKGLGVRLALDDFGTGYSSLAYLQSAPFDKIKIDQSFVRGATEPGSRNSAIIAAIVALAEALDMETTAEGI
ESLDQLDLVRKLNVSHVQGYVYSRPVPCADLVGHTEAGVWTIKPSGPARQRNDRLSLFRKVGAIHDNHRYAVVIRNLSAT
GAFIEGILDVPVGTRFVIDFGEGQLVTATVRRSMKHQQGIEFEQTMVSDGNGGLCTRHRVSPYLIAAAAQQTSALALPAF
TTTSDWKAA

Sequences:

>Translated_729_residues
MDMPSRTAPGEQGGHGVDEGPRGFFGRIGSRATRRRGDAAANLQTREALLLLQNYEESGRGWFWSTDADGRLTYITDVVA
RTMGRSAAALLGTPLTDLFLPADSHGERQRTLRFLLTRQSAFDDLPLRGAFEGGDRWWAISGRPQYDADGQFTGYRGSGT
DITAQRRSAEDASRLALYDSLTGLANRFNISKKLDATLAAFAQQQRSCAIMLLDLDRFKQVNDTLGHPAGDALLKQVAER
LLKFVGDKEMVSRLGGDEFQIILPDIDDRGKLGDMAADIIASLSQPYSVEGSRCIIGASVGVAIAPFDGQSSDDLVRNAD
LALYAAKGNGCGRFAFYSSDLHQAAEDRRALEEDLRDALARGEIALAYQPVVNARSNMVTGVEALIRWTHRDRGAISPAL
FIPIAEEANLIWPLGEWVLRKACEDAAGWPGEMRVAVNVSPIQFANPELPKVVAKALAASGLSPDRLELEITESVFLGDT
AEANRMFKALKGLGVRLALDDFGTGYSSLAYLQSAPFDKIKIDQSFVRGATEPGSRNSAIIAAIVALAEALDMETTAEGI
ESLDQLDLVRKLNVSHVQGYVYSRPVPCADLVGHTEAGVWTIKPSGPARQRNDRLSLFRKVGAIHDNHRYAVVIRNLSAT
GAFIEGILDVPVGTRFVIDFGEGQLVTATVRRSMKHQQGIEFEQTMVSDGNGGLCTRHRVSPYLIAAAAQQTSALALPAF
TTTSDWKAA
>Mature_729_residues
MDMPSRTAPGEQGGHGVDEGPRGFFGRIGSRATRRRGDAAANLQTREALLLLQNYEESGRGWFWSTDADGRLTYITDVVA
RTMGRSAAALLGTPLTDLFLPADSHGERQRTLRFLLTRQSAFDDLPLRGAFEGGDRWWAISGRPQYDADGQFTGYRGSGT
DITAQRRSAEDASRLALYDSLTGLANRFNISKKLDATLAAFAQQQRSCAIMLLDLDRFKQVNDTLGHPAGDALLKQVAER
LLKFVGDKEMVSRLGGDEFQIILPDIDDRGKLGDMAADIIASLSQPYSVEGSRCIIGASVGVAIAPFDGQSSDDLVRNAD
LALYAAKGNGCGRFAFYSSDLHQAAEDRRALEEDLRDALARGEIALAYQPVVNARSNMVTGVEALIRWTHRDRGAISPAL
FIPIAEEANLIWPLGEWVLRKACEDAAGWPGEMRVAVNVSPIQFANPELPKVVAKALAASGLSPDRLELEITESVFLGDT
AEANRMFKALKGLGVRLALDDFGTGYSSLAYLQSAPFDKIKIDQSFVRGATEPGSRNSAIIAAIVALAEALDMETTAEGI
ESLDQLDLVRKLNVSHVQGYVYSRPVPCADLVGHTEAGVWTIKPSGPARQRNDRLSLFRKVGAIHDNHRYAVVIRNLSAT
GAFIEGILDVPVGTRFVIDFGEGQLVTATVRRSMKHQQGIEFEQTMVSDGNGGLCTRHRVSPYLIAAAAQQTSALALPAF
TTTSDWKAA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=434, Percent_Identity=35.9447004608295, Blast_Score=265, Evalue=9e-72,
Organism=Escherichia coli, GI87081921, Length=435, Percent_Identity=31.0344827586207, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI226510982, Length=429, Percent_Identity=27.972027972028, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI87081980, Length=253, Percent_Identity=37.1541501976285, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI1788502, Length=258, Percent_Identity=34.8837209302326, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI87081845, Length=245, Percent_Identity=36.734693877551, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1786507, Length=297, Percent_Identity=32.3232323232323, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI87081743, Length=241, Percent_Identity=31.5352697095436, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1790496, Length=240, Percent_Identity=31.25, Blast_Score=133, Evalue=4e-32,
Organism=Escherichia coli, GI1787055, Length=288, Percent_Identity=29.8611111111111, Blast_Score=132, Evalue=9e-32,
Organism=Escherichia coli, GI1788381, Length=290, Percent_Identity=30.6896551724138, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788849, Length=260, Percent_Identity=31.9230769230769, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI87082096, Length=401, Percent_Identity=24.1895261845387, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1788956, Length=155, Percent_Identity=34.1935483870968, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081881, Length=181, Percent_Identity=33.7016574585635, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI1787262, Length=173, Percent_Identity=32.9479768786127, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI145693134, Length=183, Percent_Identity=30.6010928961749, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787802, Length=165, Percent_Identity=31.5151515151515, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI87081977, Length=152, Percent_Identity=31.5789473684211, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787816, Length=159, Percent_Identity=33.9622641509434, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI87081974, Length=167, Percent_Identity=30.5389221556886, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1787410, Length=155, Percent_Identity=26.4516129032258, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1786584, Length=174, Percent_Identity=27.5862068965517, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87082007, Length=166, Percent_Identity=28.3132530120482, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 79044; Mature: 79044

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMPSRTAPGEQGGHGVDEGPRGFFGRIGSRATRRRGDAAANLQTREALLLLQNYEESGR
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCCC
GWFWSTDADGRLTYITDVVARTMGRSAAALLGTPLTDLFLPADSHGERQRTLRFLLTRQS
CEEEECCCCCEEHHHHHHHHHHHCCCHHHHHCCCHHHHEECCCCCCHHHHHHHHHHHHHH
AFDDLPLRGAFEGGDRWWAISGRPQYDADGQFTGYRGSGTDITAQRRSAEDASRLALYDS
CCCCCCCCCEECCCCEEEEECCCCCCCCCCCEECCCCCCCCEEHHHHCCHHHHHHHHHHH
LTGLANRFNISKKLDATLAAFAQQQRSCAIMLLDLDRFKQVNDTLGHPAGDALLKQVAER
HHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHH
LLKFVGDKEMVSRLGGDEFQIILPDIDDRGKLGDMAADIIASLSQPYSVEGSRCIIGASV
HHHHHCCHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECC
GVAIAPFDGQSSDDLVRNADLALYAAKGNGCGRFAFYSSDLHQAAEDRRALEEDLRDALA
CEEEECCCCCCCCHHHHCCCEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHH
RGEIALAYQPVVNARSNMVTGVEALIRWTHRDRGAISPALFIPIAEEANLIWPLGEWVLR
CCCEEEEECCHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEECHHHHHHH
KACEDAAGWPGEMRVAVNVSPIQFANPELPKVVAKALAASGLSPDRLELEITESVFLGDT
HHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECEEEECCC
AEANRMFKALKGLGVRLALDDFGTGYSSLAYLQSAPFDKIKIDQSFVRGATEPGSRNSAI
HHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCCCEECCHHHHCCCCCCCCCCHHH
IAAIVALAEALDMETTAEGIESLDQLDLVRKLNVSHVQGYVYSRPVPCADLVGHTEAGVW
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHCCEEECCCCCHHHHCCCCCCCEE
TIKPSGPARQRNDRLSLFRKVGAIHDNHRYAVVIRNLSATGAFIEGILDVPVGTRFVIDF
EECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCEEEEEC
GEGQLVTATVRRSMKHQQGIEFEQTMVSDGNGGLCTRHRVSPYLIAAAAQQTSALALPAF
CCCCEEHHHHHHHHHHHHCCCHHHHHHCCCCCCEEECCCCCCEEEEEHHHCCCEEEECCE
TTTSDWKAA
ECCCCCCCC
>Mature Secondary Structure
MDMPSRTAPGEQGGHGVDEGPRGFFGRIGSRATRRRGDAAANLQTREALLLLQNYEESGR
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCCC
GWFWSTDADGRLTYITDVVARTMGRSAAALLGTPLTDLFLPADSHGERQRTLRFLLTRQS
CEEEECCCCCEEHHHHHHHHHHHCCCHHHHHCCCHHHHEECCCCCCHHHHHHHHHHHHHH
AFDDLPLRGAFEGGDRWWAISGRPQYDADGQFTGYRGSGTDITAQRRSAEDASRLALYDS
CCCCCCCCCEECCCCEEEEECCCCCCCCCCCEECCCCCCCCEEHHHHCCHHHHHHHHHHH
LTGLANRFNISKKLDATLAAFAQQQRSCAIMLLDLDRFKQVNDTLGHPAGDALLKQVAER
HHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHH
LLKFVGDKEMVSRLGGDEFQIILPDIDDRGKLGDMAADIIASLSQPYSVEGSRCIIGASV
HHHHHCCHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECC
GVAIAPFDGQSSDDLVRNADLALYAAKGNGCGRFAFYSSDLHQAAEDRRALEEDLRDALA
CEEEECCCCCCCCHHHHCCCEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHH
RGEIALAYQPVVNARSNMVTGVEALIRWTHRDRGAISPALFIPIAEEANLIWPLGEWVLR
CCCEEEEECCHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEECHHHHHHH
KACEDAAGWPGEMRVAVNVSPIQFANPELPKVVAKALAASGLSPDRLELEITESVFLGDT
HHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECEEEECCC
AEANRMFKALKGLGVRLALDDFGTGYSSLAYLQSAPFDKIKIDQSFVRGATEPGSRNSAI
HHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCCCEECCHHHHCCCCCCCCCCHHH
IAAIVALAEALDMETTAEGIESLDQLDLVRKLNVSHVQGYVYSRPVPCADLVGHTEAGVW
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHCCEEECCCCCHHHHCCCCCCCEE
TIKPSGPARQRNDRLSLFRKVGAIHDNHRYAVVIRNLSATGAFIEGILDVPVGTRFVIDF
EECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCEEEEEC
GEGQLVTATVRRSMKHQQGIEFEQTMVSDGNGGLCTRHRVSPYLIAAAAQQTSALALPAF
CCCCEEHHHHHHHHHHHHCCCHHHHHHCCCCCCEEECCCCCCEEEEEHHHCCCEEEECCE
TTTSDWKAA
ECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]