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The map label for this gene is nudL [H]

Identifier: 103487592

GI number: 103487592

Start: 2219638

End: 2220222

Strand: Reverse

Name: nudL [H]

Synonym: Sala_2111

Alternate gene names: 103487592

Gene position: 2220222-2219638 (Counterclockwise)

Preceding gene: 103487593

Following gene: 103487591

Centisome position: 66.37

GC content: 67.35

Gene sequence:

>585_bases
ATGCTGTCGGCCAAATTGCGCGACGCGCTCGCCAATCTGCTGCCCGAACCGGGTGAGGACGAGGCCTATCTGGGCACGCC
GACGTTGCGCGATGCCGCGGTGCTGATCGCCTTCACCGACCGCGCGGATCCCGGCGTCATCCTGACCCAGCGGCCGCAAT
GGCTGCGCAGTCATGCGGGGCAGGTGGCCTTTCCCGGCGGCAAGATCGACCCCGGCGACCGCGACGCCATCGACGCCGCG
CTGCGCGAGGCCGAGGAGGAAATCGGCCTCAGCCGCCATGATGTGATGATCGCCGGTGCAACCGAGCCCTATCGTTCGGG
AAGCGGCTATCGCATCACCCCGGTGCTCGGCGTCATCCCGCCCGACCTTCGCTTCGACCCCAATCCCGACGAGGTCGAGG
ACTGGTTCGAAGTGCCGCTCGACATATTGTTCGACCCCGGCAATTATGCGCGCCAGCACGCGCATTGGCAGGGGCAGGAC
CGGCATTATTATGACATGGAGTGGCAGGGACGGCGGATCTGGGGCGTGACCGCGGGTATCATCGTCAATCTGGCGCGCCG
CCTGCCCGCGGGGTGGCACCGGTGA

Upstream 100 bases:

>100_bases
GCGCGCTTTATTACGAAATCGTCGAGATGGCGCTCGCCGGGGGTGACGATCCGCCCGTGATATGGTCGAATGGCGCGCAA
TTTCCCCTGGTCGATCGCTG

Downstream 100 bases:

>100_bases
CGCGGCTGCCCGACGCCGCCTGGCGCGACCGGCCGGGGCTGCGCCGCATCGTCGCCGCGCTTGCCGACGATGGCGGCGCG
GTCAAGGTCGTCGGTGGCGC

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MLSAKLRDALANLLPEPGEDEAYLGTPTLRDAAVLIAFTDRADPGVILTQRPQWLRSHAGQVAFPGGKIDPGDRDAIDAA
LREAEEEIGLSRHDVMIAGATEPYRSGSGYRITPVLGVIPPDLRFDPNPDEVEDWFEVPLDILFDPGNYARQHAHWQGQD
RHYYDMEWQGRRIWGVTAGIIVNLARRLPAGWHR

Sequences:

>Translated_194_residues
MLSAKLRDALANLLPEPGEDEAYLGTPTLRDAAVLIAFTDRADPGVILTQRPQWLRSHAGQVAFPGGKIDPGDRDAIDAA
LREAEEEIGLSRHDVMIAGATEPYRSGSGYRITPVLGVIPPDLRFDPNPDEVEDWFEVPLDILFDPGNYARQHAHWQGQD
RHYYDMEWQGRRIWGVTAGIIVNLARRLPAGWHR
>Mature_194_residues
MLSAKLRDALANLLPEPGEDEAYLGTPTLRDAAVLIAFTDRADPGVILTQRPQWLRSHAGQVAFPGGKIDPGDRDAIDAA
LREAEEEIGLSRHDVMIAGATEPYRSGSGYRITPVLGVIPPDLRFDPNPDEVEDWFEVPLDILFDPGNYARQHAHWQGQD
RHYYDMEWQGRRIWGVTAGIIVNLARRLPAGWHR

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=146, Percent_Identity=34.9315068493151, Blast_Score=85, Evalue=3e-17,
Organism=Escherichia coli, GI1788115, Length=159, Percent_Identity=45.2830188679245, Blast_Score=105, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17536993, Length=111, Percent_Identity=36.9369369369369, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI18859683, Length=170, Percent_Identity=37.0588235294118, Blast_Score=87, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 21712; Mature: 21712

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSAKLRDALANLLPEPGEDEAYLGTPTLRDAAVLIAFTDRADPGVILTQRPQWLRSHAG
CCCHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEEEECCCCCCEEEECCCHHHHHCCC
QVAFPGGKIDPGDRDAIDAALREAEEEIGLSRHDVMIAGATEPYRSGSGYRITPVLGVIP
CEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEEEEEECCC
PDLRFDPNPDEVEDWFEVPLDILFDPGNYARQHAHWQGQDRHYYDMEWQGRRIWGVTAGI
CCCCCCCCCHHHHHHHHCCEEEEECCCHHHHHCCCCCCCCCEEECCCCCCCEEEEHHHHH
IVNLARRLPAGWHR
HHHHHHHCCCCCCC
>Mature Secondary Structure
MLSAKLRDALANLLPEPGEDEAYLGTPTLRDAAVLIAFTDRADPGVILTQRPQWLRSHAG
CCCHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEEEECCCCCCEEEECCCHHHHHCCC
QVAFPGGKIDPGDRDAIDAALREAEEEIGLSRHDVMIAGATEPYRSGSGYRITPVLGVIP
CEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEEEEEECCC
PDLRFDPNPDEVEDWFEVPLDILFDPGNYARQHAHWQGQDRHYYDMEWQGRRIWGVTAGI
CCCCCCCCCHHHHHHHHCCEEEEECCCHHHHHCCCCCCCCCEEECCCCCCCEEEEHHHHH
IVNLARRLPAGWHR
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]