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The map label for this gene is corA [H]

Identifier: 103487579

GI number: 103487579

Start: 2206004

End: 2206975

Strand: Reverse

Name: corA [H]

Synonym: Sala_2098

Alternate gene names: 103487579

Gene position: 2206975-2206004 (Counterclockwise)

Preceding gene: 103487580

Following gene: 103487576

Centisome position: 65.97

GC content: 62.96

Gene sequence:

>972_bases
ATGCCGATCATGGCCGCTCGCGTTTATCATCGGGGCAAGCTGGTCCGCGACCTGGGGCCGCACGAAGCGTTGCCCGAGGA
TTGCGATCCCGGCGATTTCTTCTGGCTCGGCCTGTTTGCGCCAACCCCCGAAGAGCTGTCGAGCATCGCGAAACGCTTTG
GCCTTCACCCGCTCGCGGTCGAAGATGCGCTGAAGGCGAACCAGCTGCCAAAGGTCGAGGTTTATGGTGACCAGCTATTC
GTCGTCGCGCGCACCGCCACGCTCGACGGCGAGGCGATCCACGCGGGCGAAACCGCATTGTTCCTTGGTCGGCATTTTCT
CGTGAGCGTTCGCCACGGATCGGCGCGCGCGCACACCGACGTTCGTGCCCGGCTCGAAAGCCTGCCCGCCAAGCTCGCGC
ATGGACCCGATTATGTGCTCTACGCGGTGCTCGATTTCATCGTCGACGGCTATTTCCCGGTGATCGACGCGATCGAGGAT
CGTATGCTGGGCGTCGAGGACCGGGTGATGGACACGCCGCTCAGCGCCGCGGACATTCGCCATCTCTACAAACAAAGGCA
CGAAATCATCCGTTTCCAGCGGCTCGTCGGGATGATGAAGGAAGTCGCGGCGCGGCTGGCCAATGGCGACGAATTGCCCG
CGATCGACCCCGTCGTGCGCCCCTTTTTCCGTGACGTCTGGGACCATGTCCAGCGTGCCGAATATCGTCTGGCGGGGCTG
CGCGACATTGCGGTGTCGGTGATCGAAACCAACGGGATGCTCGAACAACAACGCCAGGGCGCGATCACCCGCCAGCTCGC
GGCGTGGGCTGCGATCCTCGCGGTTCCGACCGCGATCGCAGGCATTTATGGGATGAACTTCGACTATATGCCCGAACTTC
GCTGGCCCTTCGGCTATCCGCTGATCGTCGGCGGCATGACCGCGATCTGCCTCACCCTCTATTGGCGCTTCAAACGCATC
GGCTGGCTCTGA

Upstream 100 bases:

>100_bases
TAGGCCGGATTGGTGGCGACGGCGGCTCCGGTCCGTTGGGGATTCCCGTTGGGCGGTGCAGTCCCTATAGGACGGCTTCG
ACAAAGGAGGATCGTCCGCA

Downstream 100 bases:

>100_bases
TAGCCCGACGCACGGCTTGCCAGCCGCGGCGCCTTGTGGCAGGGGCGCGCTTCCCTTCGGGGGCGCTTAGCTCAGCTGGT
AGAGCATCTCGTTTACACCG

Product: magnesium and cobalt transport protein CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MPIMAARVYHRGKLVRDLGPHEALPEDCDPGDFFWLGLFAPTPEELSSIAKRFGLHPLAVEDALKANQLPKVEVYGDQLF
VVARTATLDGEAIHAGETALFLGRHFLVSVRHGSARAHTDVRARLESLPAKLAHGPDYVLYAVLDFIVDGYFPVIDAIED
RMLGVEDRVMDTPLSAADIRHLYKQRHEIIRFQRLVGMMKEVAARLANGDELPAIDPVVRPFFRDVWDHVQRAEYRLAGL
RDIAVSVIETNGMLEQQRQGAITRQLAAWAAILAVPTAIAGIYGMNFDYMPELRWPFGYPLIVGGMTAICLTLYWRFKRI
GWL

Sequences:

>Translated_323_residues
MPIMAARVYHRGKLVRDLGPHEALPEDCDPGDFFWLGLFAPTPEELSSIAKRFGLHPLAVEDALKANQLPKVEVYGDQLF
VVARTATLDGEAIHAGETALFLGRHFLVSVRHGSARAHTDVRARLESLPAKLAHGPDYVLYAVLDFIVDGYFPVIDAIED
RMLGVEDRVMDTPLSAADIRHLYKQRHEIIRFQRLVGMMKEVAARLANGDELPAIDPVVRPFFRDVWDHVQRAEYRLAGL
RDIAVSVIETNGMLEQQRQGAITRQLAAWAAILAVPTAIAGIYGMNFDYMPELRWPFGYPLIVGGMTAICLTLYWRFKRI
GWL
>Mature_322_residues
PIMAARVYHRGKLVRDLGPHEALPEDCDPGDFFWLGLFAPTPEELSSIAKRFGLHPLAVEDALKANQLPKVEVYGDQLFV
VARTATLDGEAIHAGETALFLGRHFLVSVRHGSARAHTDVRARLESLPAKLAHGPDYVLYAVLDFIVDGYFPVIDAIEDR
MLGVEDRVMDTPLSAADIRHLYKQRHEIIRFQRLVGMMKEVAARLANGDELPAIDPVVRPFFRDVWDHVQRAEYRLAGLR
DIAVSVIETNGMLEQQRQGAITRQLAAWAAILAVPTAIAGIYGMNFDYMPELRWPFGYPLIVGGMTAICLTLYWRFKRIG
WL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321058, Length=198, Percent_Identity=30.3030303030303, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324442, Length=196, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36312; Mature: 36180

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIMAARVYHRGKLVRDLGPHEALPEDCDPGDFFWLGLFAPTPEELSSIAKRFGLHPLAV
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCHHH
EDALKANQLPKVEVYGDQLFVVARTATLDGEAIHAGETALFLGRHFLVSVRHGSARAHTD
HHHHHHCCCCEEEEECCEEEEEEEEEECCCCEEECCCHHHHHHHHHEEEEECCCCHHHHH
VRARLESLPAKLAHGPDYVLYAVLDFIVDGYFPVIDAIEDRMLGVEDRVMDTPLSAADIR
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHCCCCCHHHHH
HLYKQRHEIIRFQRLVGMMKEVAARLANGDELPAIDPVVRPFFRDVWDHVQRAEYRLAGL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RDIAVSVIETNGMLEQQRQGAITRQLAAWAAILAVPTAIAGIYGMNFDYMPELRWPFGYP
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
LIVGGMTAICLTLYWRFKRIGWL
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PIMAARVYHRGKLVRDLGPHEALPEDCDPGDFFWLGLFAPTPEELSSIAKRFGLHPLAV
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCHHH
EDALKANQLPKVEVYGDQLFVVARTATLDGEAIHAGETALFLGRHFLVSVRHGSARAHTD
HHHHHHCCCCEEEEECCEEEEEEEEEECCCCEEECCCHHHHHHHHHEEEEECCCCHHHHH
VRARLESLPAKLAHGPDYVLYAVLDFIVDGYFPVIDAIEDRMLGVEDRVMDTPLSAADIR
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHCCCCCHHHHH
HLYKQRHEIIRFQRLVGMMKEVAARLANGDELPAIDPVVRPFFRDVWDHVQRAEYRLAGL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RDIAVSVIETNGMLEQQRQGAITRQLAAWAAILAVPTAIAGIYGMNFDYMPELRWPFGYP
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
LIVGGMTAICLTLYWRFKRIGWL
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]