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The map label for this gene is spoVD [H]

Identifier: 103487371

GI number: 103487371

Start: 1986493

End: 1988181

Strand: Reverse

Name: spoVD [H]

Synonym: Sala_1887

Alternate gene names: 103487371

Gene position: 1988181-1986493 (Counterclockwise)

Preceding gene: 103487372

Following gene: 103487370

Centisome position: 59.43

GC content: 66.31

Gene sequence:

>1689_bases
ATGAACACGCTGGTCGTCCGTCCGACCCGGGTGCGTACCGCCGGTGTGCGGCAGCAGATCCTGCTGACCGCGCAACAGCG
TTTGATGATCCTCATGCTGCTGTTCGCGGCGGCTTTTCTCCTTGTGTCGATGCGGCTTGTCTATTTTGTGCTCTTCGACA
CCTCTGCGGGGCAGCGATCGGCGGGCGCCTTCATTCCCGCGCGCGCCGACATCGTCGATCGCAACGGCGTGCCGCTGGCG
CGGACGATCGACGGTTATTCGATCCGCGTCGTGCCATCGAAGCTGCTCAACGACCGCAATTATCTGGCGGGTGAGTTGCA
CCGGATTTTTCCCGACATGTCGCGCGCCGATTTGCTCGCGAAGCTGACGGGGCCGCGGCCAACCTATATCCGCCGCCGCG
CGCTTCCCGACCAGGTGGCGGCGGTGAACGCGATCGGCGATGTCGGTTTCGATTTCCCGCGCGAAAAGGAGCGGCTTTAC
CCGCAGCTGACGCTTGCGGCGCATGTGCTCGGCTTTACCAATGCCGAAGGGCATGGCGTCACCGGCGTCGAGGGCGCGTT
CGACCAACGGCTGATCGACAAGGCGACGCGCGGCGAGCCGCTGGCGCTGTCGATCGACGCGCGCGTTCAGGGTGTCCTCG
AAAGCGAACTCGGCGCCGCGGTCGCCAATCTGGAGGCGATCGGCGGCGCCGGCGTCATCCTCGACGTCCACACCGGCGAG
GTGGCGGCGATGACGTCGCTGCCGACCTTTAATCCCAACAAGCTCACCGGCAGCGACCCGACGACGCGGCGCAATGCCGT
CACCTATAATCTTTACGAGCTGGGTTCGACCTTCAAGCCATTGTCGATTGGCGCCGCGATCGACAATGGGACGGTGACGA
ACATGGCGCGCCGCTACGATGCGTCGGCGCCGCTGCCGATCGCCGGTTTCCGCATTCGCGACAGCCATCCGGGGCGCTGG
TACAATGTGCCCGAAACGCTGATCGAAAGCTCGAATATCGCAACCGCGCGCATTGCCGATGATATGGGCCGCGAGCCGCT
GGAAAAACTGTTCCGCGCCCTTCATTTCGACCAACGCCCCGACATCGAGCTGAAAGAGCGCGCCTTCCCGCTGTGGCCGA
AGCACTGGGGGCGCGTGACGACGATGACGACCAGCTATGGCCACGGCATCGCGGTGACGCCGCTGCATCTCGCCAGCGCC
TATGCGGCGCTGGTCAACGGCGGCATCTATCGCCCGGCGACGCTGCTCAAGCTCGGCGACAGGGCGCCGCCGCAGGGGCG
CCGCGTATTCAAGGCCGCGACCAGCGCGCGGATGCGCCAGCTGCTTCGCCTGATCGTGTCCGACGGCACTGGCAAACAGG
CGGACGCGCCGGGGTTCCGCGTCGGCGGCAAGACCGGATCGGCGGAAAAGCCGGGCGCGGGCGGTTATCGCCGCCACTCG
CTCGTCTCGACCTTTGCGGCCGCCTTCCCGATGGACAATCCGCGCTATGTCGTGATCGTGATGATCGACGAGCCGAAGGG
CAACGCCTATAGTTCGGGGCAGCGCACCGCGGGCTGGACCGCGGCGCCGGTGGTGCGCAAGGTCGTGACGCGCGCGGGAC
CGATGCTTGGCGTCTTCCCTGACCAGAGCCGCGACGTCGACGTGTCCGAACTCACCCCGTTGCTGCGGAGAAACGAGGAG
GCGCCCTGA

Upstream 100 bases:

>100_bases
AGCAATTGAAGATGATCGAGGACCAGCTGCTCGCCGAATCGACGCTCGCCGATTTGAAGCGCGACGCGGCGATCGAAGCG
GCAGGAGGCAAGCCCGCCCG

Downstream 100 bases:

>100_bases
TGCGTCTCGCCGCGCTGCTGGACGATGCCGACTGGGCGGGGCCCAATCCCGTCGTCACCGGGCTTGCCATCGATCATCGC
AAAGTGGCGCCGGGAACACT

Product: peptidoglycan glycosyltransferase

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MNTLVVRPTRVRTAGVRQQILLTAQQRLMILMLLFAAAFLLVSMRLVYFVLFDTSAGQRSAGAFIPARADIVDRNGVPLA
RTIDGYSIRVVPSKLLNDRNYLAGELHRIFPDMSRADLLAKLTGPRPTYIRRRALPDQVAAVNAIGDVGFDFPREKERLY
PQLTLAAHVLGFTNAEGHGVTGVEGAFDQRLIDKATRGEPLALSIDARVQGVLESELGAAVANLEAIGGAGVILDVHTGE
VAAMTSLPTFNPNKLTGSDPTTRRNAVTYNLYELGSTFKPLSIGAAIDNGTVTNMARRYDASAPLPIAGFRIRDSHPGRW
YNVPETLIESSNIATARIADDMGREPLEKLFRALHFDQRPDIELKERAFPLWPKHWGRVTTMTTSYGHGIAVTPLHLASA
YAALVNGGIYRPATLLKLGDRAPPQGRRVFKAATSARMRQLLRLIVSDGTGKQADAPGFRVGGKTGSAEKPGAGGYRRHS
LVSTFAAAFPMDNPRYVVIVMIDEPKGNAYSSGQRTAGWTAAPVVRKVVTRAGPMLGVFPDQSRDVDVSELTPLLRRNEE
AP

Sequences:

>Translated_562_residues
MNTLVVRPTRVRTAGVRQQILLTAQQRLMILMLLFAAAFLLVSMRLVYFVLFDTSAGQRSAGAFIPARADIVDRNGVPLA
RTIDGYSIRVVPSKLLNDRNYLAGELHRIFPDMSRADLLAKLTGPRPTYIRRRALPDQVAAVNAIGDVGFDFPREKERLY
PQLTLAAHVLGFTNAEGHGVTGVEGAFDQRLIDKATRGEPLALSIDARVQGVLESELGAAVANLEAIGGAGVILDVHTGE
VAAMTSLPTFNPNKLTGSDPTTRRNAVTYNLYELGSTFKPLSIGAAIDNGTVTNMARRYDASAPLPIAGFRIRDSHPGRW
YNVPETLIESSNIATARIADDMGREPLEKLFRALHFDQRPDIELKERAFPLWPKHWGRVTTMTTSYGHGIAVTPLHLASA
YAALVNGGIYRPATLLKLGDRAPPQGRRVFKAATSARMRQLLRLIVSDGTGKQADAPGFRVGGKTGSAEKPGAGGYRRHS
LVSTFAAAFPMDNPRYVVIVMIDEPKGNAYSSGQRTAGWTAAPVVRKVVTRAGPMLGVFPDQSRDVDVSELTPLLRRNEE
AP
>Mature_562_residues
MNTLVVRPTRVRTAGVRQQILLTAQQRLMILMLLFAAAFLLVSMRLVYFVLFDTSAGQRSAGAFIPARADIVDRNGVPLA
RTIDGYSIRVVPSKLLNDRNYLAGELHRIFPDMSRADLLAKLTGPRPTYIRRRALPDQVAAVNAIGDVGFDFPREKERLY
PQLTLAAHVLGFTNAEGHGVTGVEGAFDQRLIDKATRGEPLALSIDARVQGVLESELGAAVANLEAIGGAGVILDVHTGE
VAAMTSLPTFNPNKLTGSDPTTRRNAVTYNLYELGSTFKPLSIGAAIDNGTVTNMARRYDASAPLPIAGFRIRDSHPGRW
YNVPETLIESSNIATARIADDMGREPLEKLFRALHFDQRPDIELKERAFPLWPKHWGRVTTMTTSYGHGIAVTPLHLASA
YAALVNGGIYRPATLLKLGDRAPPQGRRVFKAATSARMRQLLRLIVSDGTGKQADAPGFRVGGKTGSAEKPGAGGYRRHS
LVSTFAAAFPMDNPRYVVIVMIDEPKGNAYSSGQRTAGWTAAPVVRKVVTRAGPMLGVFPDQSRDVDVSELTPLLRRNEE
AP

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=561, Percent_Identity=28.3422459893048, Blast_Score=195, Evalue=7e-51,
Organism=Escherichia coli, GI1786854, Length=587, Percent_Identity=25.2129471890971, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 61090; Mature: 61090

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLVVRPTRVRTAGVRQQILLTAQQRLMILMLLFAAAFLLVSMRLVYFVLFDTSAGQRS
CCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCC
AGAFIPARADIVDRNGVPLARTIDGYSIRVVPSKLLNDRNYLAGELHRIFPDMSRADLLA
CCCCCCCCCCEECCCCCCEEEECCCEEEEEECHHHCCCCCHHHHHHHHHCCCCHHHHHHH
KLTGPRPTYIRRRALPDQVAAVNAIGDVGFDFPREKERLYPQLTLAAHVLGFTNAEGHGV
HCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHHCCCCCCCCC
TGVEGAFDQRLIDKATRGEPLALSIDARVQGVLESELGAAVANLEAIGGAGVILDVHTGE
CCCCCHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
VAAMTSLPTFNPNKLTGSDPTTRRNAVTYNLYELGSTFKPLSIGAAIDNGTVTNMARRYD
EEEEECCCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCCEEECEEECCCHHHHHHHHCC
ASAPLPIAGFRIRDSHPGRWYNVPETLIESSNIATARIADDMGREPLEKLFRALHFDQRP
CCCCCCEEEEEEECCCCCCEECCHHHHHCCCCCEEEHHHHHCCHHHHHHHHHHHCCCCCC
DIELKERAFPLWPKHWGRVTTMTTSYGHGIAVTPLHLASAYAALVNGGIYRPATLLKLGD
CCCHHHCCCCCCHHHCCEEEEEEECCCCCEEECHHHHHHHHHHHHCCCCCCCCHHHCCCC
RAPPQGRRVFKAATSARMRQLLRLIVSDGTGKQADAPGFRVGGKTGSAEKPGAGGYRRHS
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHH
LVSTFAAAFPMDNPRYVVIVMIDEPKGNAYSSGQRTAGWTAAPVVRKVVTRAGPMLGVFP
HHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECC
DQSRDVDVSELTPLLRRNEEAP
CCCCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNTLVVRPTRVRTAGVRQQILLTAQQRLMILMLLFAAAFLLVSMRLVYFVLFDTSAGQRS
CCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCC
AGAFIPARADIVDRNGVPLARTIDGYSIRVVPSKLLNDRNYLAGELHRIFPDMSRADLLA
CCCCCCCCCCEECCCCCCEEEECCCEEEEEECHHHCCCCCHHHHHHHHHCCCCHHHHHHH
KLTGPRPTYIRRRALPDQVAAVNAIGDVGFDFPREKERLYPQLTLAAHVLGFTNAEGHGV
HCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHHCCCCCCCCC
TGVEGAFDQRLIDKATRGEPLALSIDARVQGVLESELGAAVANLEAIGGAGVILDVHTGE
CCCCCHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
VAAMTSLPTFNPNKLTGSDPTTRRNAVTYNLYELGSTFKPLSIGAAIDNGTVTNMARRYD
EEEEECCCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCCEEECEEECCCHHHHHHHHCC
ASAPLPIAGFRIRDSHPGRWYNVPETLIESSNIATARIADDMGREPLEKLFRALHFDQRP
CCCCCCEEEEEEECCCCCCEECCHHHHHCCCCCEEEHHHHHCCHHHHHHHHHHHCCCCCC
DIELKERAFPLWPKHWGRVTTMTTSYGHGIAVTPLHLASAYAALVNGGIYRPATLLKLGD
CCCHHHCCCCCCHHHCCEEEEEEECCCCCEEECHHHHHHHHHHHHCCCCCCCCHHHCCCC
RAPPQGRRVFKAATSARMRQLLRLIVSDGTGKQADAPGFRVGGKTGSAEKPGAGGYRRHS
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHH
LVSTFAAAFPMDNPRYVVIVMIDEPKGNAYSSGQRTAGWTAAPVVRKVVTRAGPMLGVFP
HHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECC
DQSRDVDVSELTPLLRRNEEAP
CCCCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]