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The map label for this gene is mraY

Identifier: 103487368

GI number: 103487368

Start: 1982608

End: 1983678

Strand: Reverse

Name: mraY

Synonym: Sala_1884

Alternate gene names: 103487368

Gene position: 1983678-1982608 (Counterclockwise)

Preceding gene: 103487369

Following gene: 103487367

Centisome position: 59.3

GC content: 63.4

Gene sequence:

>1071_bases
ATGTTATACTGGCTGGCGGAATGGCTTGGCTTTCCGGGGGCGCTCAATCTCATCCGCTACCTGAGCTTCCGCTCGGGCGC
TGCGGTTGCGACCGCGATGATCCTCGGCCTGTGGATCGGTCCGCGCTTCATCCTGATGCTGCGGATGCGGCAGGGCAAGG
GGCAGCCGATCCGCGACGACGGCCCGCAAAGCCATCTTGCCAAAAAGGGCACGCCGACGATGGGCGGGCTGATGATCCTC
ATTTCGCTGATGATCTCCGCGCTCCTCTGGATGGACCTCTCCAACCGCTTTGTCTGGGCCTGTCTGTTCGTCACCGCGGG
CTTTGCGGTCGTCGGTTTCCTCGACGATTATGACAAGGTGACCAAATCGAGCCATCGCGGCATTCCGGGGCGGGTGCGGC
TGCTTGTCGAGTTCCTCATCGCCGGGGTCGCGGTGTTGCTGATCGTCTCGCGCACGGGCACCGACCTCTATCTGCCCTTT
TTCAGCGGCATCGTGATTCCGCTCGGCCCCTTTTATTATGTTTTCGCGATGGTGCTGATCGTCGGTTTCGGCAATGCCGT
GAACCTGACCGACGGGCTCGACGGGCTCGCGACATTCCCGGTCATCATCGCCAGCCTGACCTTCCTTGTCATCGTCTATC
TGTCGGGCAACGTGAAGTTCGCCGGCTATCTCGGCATCCCGCATGTCCCCGGCGCGGGCGAGCTGGCCGTATTTGCCGCG
GCGATCATCGGCGCCTGCCTCGCCTTCCTGTGGTTCAACGCGCCCCCCGCGGCGGTGTTCATGGGCGACACGGGCAGCCT
TGCGCTCGGCGGTGCGCTGGCGACGATCGCGGTGACGGCGCAGCATGAACTTGTGCTCGTCCTCGTCGGCGGGCTGTTCG
TTGTCGAGGCGCTGTCGGTGATCATCCAGGTCTTCTGGTACAAGCGCACCGGCAAGCGCGTGTTTCGCATGGCGCCGATC
CACCATCATTTCGAGCAGCTCGGCTGGCCCGAATCCACCGTCGTCATTCGCTTCTGGATCGTCTCGATCGTCCTGGCGCT
TGCGGGACTCGCGACCTTGAAGCTGCGGTGA

Upstream 100 bases:

>100_bases
TGGGCGGCCTCATCCGTCCCGGCGATGCAGTGCTCGTCAAGGGATCGAACAGCGTCGGCCTGTCGCATGTCGTGACGGCG
CTGATCAACGGGGATTATTG

Downstream 100 bases:

>100_bases
TTACCTCGCGCGCCTTTGCCGGTCGCCGCTATGCGGTGCTGGGACTGGCGCGCTCGGGGCTGGCCACCGTCGAGGCGCTT
GTCGCCAGCGGCGCGGGCGT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MLYWLAEWLGFPGALNLIRYLSFRSGAAVATAMILGLWIGPRFILMLRMRQGKGQPIRDDGPQSHLAKKGTPTMGGLMIL
ISLMISALLWMDLSNRFVWACLFVTAGFAVVGFLDDYDKVTKSSHRGIPGRVRLLVEFLIAGVAVLLIVSRTGTDLYLPF
FSGIVIPLGPFYYVFAMVLIVGFGNAVNLTDGLDGLATFPVIIASLTFLVIVYLSGNVKFAGYLGIPHVPGAGELAVFAA
AIIGACLAFLWFNAPPAAVFMGDTGSLALGGALATIAVTAQHELVLVLVGGLFVVEALSVIIQVFWYKRTGKRVFRMAPI
HHHFEQLGWPESTVVIRFWIVSIVLALAGLATLKLR

Sequences:

>Translated_356_residues
MLYWLAEWLGFPGALNLIRYLSFRSGAAVATAMILGLWIGPRFILMLRMRQGKGQPIRDDGPQSHLAKKGTPTMGGLMIL
ISLMISALLWMDLSNRFVWACLFVTAGFAVVGFLDDYDKVTKSSHRGIPGRVRLLVEFLIAGVAVLLIVSRTGTDLYLPF
FSGIVIPLGPFYYVFAMVLIVGFGNAVNLTDGLDGLATFPVIIASLTFLVIVYLSGNVKFAGYLGIPHVPGAGELAVFAA
AIIGACLAFLWFNAPPAAVFMGDTGSLALGGALATIAVTAQHELVLVLVGGLFVVEALSVIIQVFWYKRTGKRVFRMAPI
HHHFEQLGWPESTVVIRFWIVSIVLALAGLATLKLR
>Mature_356_residues
MLYWLAEWLGFPGALNLIRYLSFRSGAAVATAMILGLWIGPRFILMLRMRQGKGQPIRDDGPQSHLAKKGTPTMGGLMIL
ISLMISALLWMDLSNRFVWACLFVTAGFAVVGFLDDYDKVTKSSHRGIPGRVRLLVEFLIAGVAVLLIVSRTGTDLYLPF
FSGIVIPLGPFYYVFAMVLIVGFGNAVNLTDGLDGLATFPVIIASLTFLVIVYLSGNVKFAGYLGIPHVPGAGELAVFAA
AIIGACLAFLWFNAPPAAVFMGDTGSLALGGALATIAVTAQHELVLVLVGGLFVVEALSVIIQVFWYKRTGKRVFRMAPI
HHHFEQLGWPESTVVIRFWIVSIVLALAGLATLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=361, Percent_Identity=51.2465373961219, Blast_Score=338, Evalue=4e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_SPHAL (Q1GRX6)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_616929.1
- GeneID:   4082629
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_1884
- NMPDR:   fig|317655.9.peg.1812
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- BioCyc:   SALA317655:SALA_1884-MONOMER
- BRENDA:   2.7.8.13
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 38555; Mature: 38555

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1294aba0)-; HASH(0x1367f800)-; HASH(0x136a0df4)-; HASH(0x1366b230)-; HASH(0x136a3190)-; HASH(0x1367bb3c)-; HASH(0x1366b4e8)-; HASH(0x136a0e78)-; HASH(0x12d9dbbc)-; HASH(0x12cb3fb8)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYWLAEWLGFPGALNLIRYLSFRSGAAVATAMILGLWIGPRFILMLRMRQGKGQPIRDD
CCEEHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GPQSHLAKKGTPTMGGLMILISLMISALLWMDLSNRFVWACLFVTAGFAVVGFLDDYDKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
TKSSHRGIPGRVRLLVEFLIAGVAVLLIVSRTGTDLYLPFFSGIVIPLGPFYYVFAMVLI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCHHHCCCHHHHHHHHHHH
VGFGNAVNLTDGLDGLATFPVIIASLTFLVIVYLSGNVKFAGYLGIPHVPGAGELAVFAA
HHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHH
AIIGACLAFLWFNAPPAAVFMGDTGSLALGGALATIAVTAQHELVLVLVGGLFVVEALSV
HHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHH
IIQVFWYKRTGKRVFRMAPIHHHFEQLGWPESTVVIRFWIVSIVLALAGLATLKLR
HHHHHHHHHCCCHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MLYWLAEWLGFPGALNLIRYLSFRSGAAVATAMILGLWIGPRFILMLRMRQGKGQPIRDD
CCEEHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GPQSHLAKKGTPTMGGLMILISLMISALLWMDLSNRFVWACLFVTAGFAVVGFLDDYDKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
TKSSHRGIPGRVRLLVEFLIAGVAVLLIVSRTGTDLYLPFFSGIVIPLGPFYYVFAMVLI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCHHHCCCHHHHHHHHHHH
VGFGNAVNLTDGLDGLATFPVIIASLTFLVIVYLSGNVKFAGYLGIPHVPGAGELAVFAA
HHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHH
AIIGACLAFLWFNAPPAAVFMGDTGSLALGGALATIAVTAQHELVLVLVGGLFVVEALSV
HHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHH
IIQVFWYKRTGKRVFRMAPIHHHFEQLGWPESTVVIRFWIVSIVLALAGLATLKLR
HHHHHHHHHCCCHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA