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The map label for this gene is arsC [H]

Identifier: 103487310

GI number: 103487310

Start: 1922279

End: 1922623

Strand: Reverse

Name: arsC [H]

Synonym: Sala_1826

Alternate gene names: 103487310

Gene position: 1922623-1922279 (Counterclockwise)

Preceding gene: 103487312

Following gene: 103487308

Centisome position: 57.47

GC content: 66.38

Gene sequence:

>345_bases
ATGAAAGCGACCATCTGGCACAACCCCGCCTGCGGCACCTCGCGCAACACTCTGGCGATCCTTGATGCGACGCCGGACGT
CGAGCTGACGGTGATCGAATATCTCAAAAATCCCTATGAAGCGGCGAAGCTGCGCCAGCTTTTCGCCGACGCCGGGCTGG
CGCCGCGCGACGCGCTGCGCCTGCGCGGCACCGATGCCGCCGAGCGCGGCCTGCCCGATGCCGACGCCGATACGATCATC
GCGGCGATGGCGGCGAATCCCGCCTATGTCGAGCGCCCCTTCGTCGAAACCGAAAAGGGCGTGCGGCTGTGCCGACCGCA
GGACAAGGTGCGCGAAATCCTCTGA

Upstream 100 bases:

>100_bases
AAAGGCAAGCTGGTGGTTCCCCTTCATGCGGGCAAATGTGCCATATATGCCATGAATAGCGGGTTTACGCTGCGGTAAGG
CGGCGTTAGGACGCACGCGC

Downstream 100 bases:

>100_bases
TCGAGGCTCAGAGCAGCGCCTCGATCGCCTCCGCGAGCTTCGCGTCGCGCTCCGAAAGTCCGTTGGCATCGTGCGTCGTC
AGCAGCACGTCGACGCGGTT

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MKATIWHNPACGTSRNTLAILDATPDVELTVIEYLKNPYEAAKLRQLFADAGLAPRDALRLRGTDAAERGLPDADADTII
AAMAANPAYVERPFVETEKGVRLCRPQDKVREIL

Sequences:

>Translated_114_residues
MKATIWHNPACGTSRNTLAILDATPDVELTVIEYLKNPYEAAKLRQLFADAGLAPRDALRLRGTDAAERGLPDADADTII
AAMAANPAYVERPFVETEKGVRLCRPQDKVREIL
>Mature_114_residues
MKATIWHNPACGTSRNTLAILDATPDVELTVIEYLKNPYEAAKLRQLFADAGLAPRDALRLRGTDAAERGLPDADADTII
AAMAANPAYVERPFVETEKGVRLCRPQDKVREIL

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=113, Percent_Identity=43.3628318584071, Blast_Score=83, Evalue=5e-18,
Organism=Escherichia coli, GI1788841, Length=116, Percent_Identity=36.2068965517241, Blast_Score=66, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 12518; Mature: 12518

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKATIWHNPACGTSRNTLAILDATPDVELTVIEYLKNPYEAAKLRQLFADAGLAPRDALR
CCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHEE
LRGTDAAERGLPDADADTIIAAMAANPAYVERPFVETEKGVRLCRPQDKVREIL
ECCCCHHHCCCCCCCHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCHHHHHHCC
>Mature Secondary Structure
MKATIWHNPACGTSRNTLAILDATPDVELTVIEYLKNPYEAAKLRQLFADAGLAPRDALR
CCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHEE
LRGTDAAERGLPDADADTIIAAMAANPAYVERPFVETEKGVRLCRPQDKVREIL
ECCCCHHHCCCCCCCHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3021763; 1703401; 1704144 [H]