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The map label for this gene is exuT [H]

Identifier: 103487151

GI number: 103487151

Start: 1753403

End: 1754638

Strand: Reverse

Name: exuT [H]

Synonym: Sala_1666

Alternate gene names: 103487151

Gene position: 1754638-1753403 (Counterclockwise)

Preceding gene: 103487153

Following gene: 103487150

Centisome position: 52.45

GC content: 64.08

Gene sequence:

>1236_bases
ATGGCGACGGCAGCAGCGCAGGGGGACCGGTCGACACGCATCGCGATCGTGCTGGTCACGCTGCTTTTCCTGGGCAATGC
CCTCAACTATGTCGACCGGCAGGTTCTCGCTCTTCTGAAACCCACGCTGGAAGCCGAGTTCGGCTGGAGTGATTCGGATT
ACGCGCATCTGGGCTCGACATTCCAGATCGCGGCTGCCGGGGCGCTTCTCGGTGTCGGGTGGTTCGTCGATCGTCTCGGG
GTGCGCTGGGCCTATGCGATCGCGATATCGGTGTGGAGCCTGGCGGGCATGGCGCACGCGCTTGCGCAAAGCGTTCAGCA
GTTTGTTGCGGCGCGCGTCGTGCTGGCGGTCGGGGAATCGGTCAGTACCCCCGCCGGTATCAAGACGGCGGCGACCTATC
TGCCGGTGCGGCAGCGCAATATGGCGATCGGGCTGATCAATACCGCGCCCAACATCGGCGCGATTGTCACGCCGCTCCTG
ATCCCGCCGCTGGCGCTGGCCTTTGGCTGGAAGGCCGCGTTTATCGCCACCGGTGCGCTCGGTTTTGTGTGGCTCGCATT
CTGGCTTCCGGCGATGCGCAAAATGCGACCGCTCGGCGACCTCCCCGAACGCGCGAAAGTCGCATGGCGTCCGCTGCTTC
GCGACCGCCGGACCTGGGCCGTGGTCGGCGCGAAGTTCTGCACCGATTGCGTGTGGTGGTTCGTGCTCTTCTGGATGCCC
GACTTTTTCAGCCGGGAGTTCGGAATGAGCCAGGGGGCGCTCGGCCTGCCCATCGCAATTGTCTTCACGCTGGCGGCGCT
CGGCGCGGTCACGTCGGGGGCGCTCTATCCGATCCTTCTCGGACGCGGTTTTTCGGTGGATCGCGCGCGCAAATTGTCGA
TGTTCGTCTTCGCCCTCGCCGTGCTGGTGATGCCGCTCGCCATGTACACCACCAGTCCCTGGGTGGCAGCGCTGTGCGTC
GGCCTCGGACTGTTTGCTCATCAGGGTTTTTCGACGAACATCTTTGGCATGACTGCCGACATCATCCCGCCGCTGCGCGT
CGCGACCGTGATCGCGCTCGGCGCGGTCGCAGGCAATTTGTCCGGCACCGCGATCATCGAATTTGCTGGTTGGTCGCTTG
GAAACGGGCTGGGTTACGGGCCGCTTTTTATAATCTGCAGCCTTGCCTATCTCACGGCGCTTCTGGTGATTCACCTTATC
GTGCCGCGGCTCGAACTCGCTGAGTCGCGCGCCTAG

Upstream 100 bases:

>100_bases
GTCCTACGGTATGTCCTACGGTGTCATATTTTTCTTCCCTTATCGGCAGCGGGCGCTAGGTTGCAAGTCGAAACAGCTCA
AAGGGCGAGGGAGAGAGGTC

Downstream 100 bases:

>100_bases
AGCGCGATGACATGATATTGACCCACCGTGATTGCCCCCTGAAGTTCGTCGGCAAGAAGCATCTCGCAGGACGGGCTGGT
TGCCCGGACCAGAGACGCGC

Product: major facilitator transporter

Products: galacturonate [Cytoplasm]; Proton [Cytoplasm]; glucuronate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MATAAAQGDRSTRIAIVLVTLLFLGNALNYVDRQVLALLKPTLEAEFGWSDSDYAHLGSTFQIAAAGALLGVGWFVDRLG
VRWAYAIAISVWSLAGMAHALAQSVQQFVAARVVLAVGESVSTPAGIKTAATYLPVRQRNMAIGLINTAPNIGAIVTPLL
IPPLALAFGWKAAFIATGALGFVWLAFWLPAMRKMRPLGDLPERAKVAWRPLLRDRRTWAVVGAKFCTDCVWWFVLFWMP
DFFSREFGMSQGALGLPIAIVFTLAALGAVTSGALYPILLGRGFSVDRARKLSMFVFALAVLVMPLAMYTTSPWVAALCV
GLGLFAHQGFSTNIFGMTADIIPPLRVATVIALGAVAGNLSGTAIIEFAGWSLGNGLGYGPLFIICSLAYLTALLVIHLI
VPRLELAESRA

Sequences:

>Translated_411_residues
MATAAAQGDRSTRIAIVLVTLLFLGNALNYVDRQVLALLKPTLEAEFGWSDSDYAHLGSTFQIAAAGALLGVGWFVDRLG
VRWAYAIAISVWSLAGMAHALAQSVQQFVAARVVLAVGESVSTPAGIKTAATYLPVRQRNMAIGLINTAPNIGAIVTPLL
IPPLALAFGWKAAFIATGALGFVWLAFWLPAMRKMRPLGDLPERAKVAWRPLLRDRRTWAVVGAKFCTDCVWWFVLFWMP
DFFSREFGMSQGALGLPIAIVFTLAALGAVTSGALYPILLGRGFSVDRARKLSMFVFALAVLVMPLAMYTTSPWVAALCV
GLGLFAHQGFSTNIFGMTADIIPPLRVATVIALGAVAGNLSGTAIIEFAGWSLGNGLGYGPLFIICSLAYLTALLVIHLI
VPRLELAESRA
>Mature_410_residues
ATAAAQGDRSTRIAIVLVTLLFLGNALNYVDRQVLALLKPTLEAEFGWSDSDYAHLGSTFQIAAAGALLGVGWFVDRLGV
RWAYAIAISVWSLAGMAHALAQSVQQFVAARVVLAVGESVSTPAGIKTAATYLPVRQRNMAIGLINTAPNIGAIVTPLLI
PPLALAFGWKAAFIATGALGFVWLAFWLPAMRKMRPLGDLPERAKVAWRPLLRDRRTWAVVGAKFCTDCVWWFVLFWMPD
FFSREFGMSQGALGLPIAIVFTLAALGAVTSGALYPILLGRGFSVDRARKLSMFVFALAVLVMPLAMYTTSPWVAALCVG
LGLFAHQGFSTNIFGMTADIIPPLRVATVIALGAVAGNLSGTAIIEFAGWSLGNGLGYGPLFIICSLAYLTALLVIHLIV
PRLELAESRA

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=368, Percent_Identity=22.554347826087, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI2367193, Length=415, Percent_Identity=27.2289156626506, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI2367379, Length=352, Percent_Identity=27.5568181818182, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI87082320, Length=424, Percent_Identity=25.9433962264151, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1789515, Length=399, Percent_Identity=24.3107769423559, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1789152, Length=443, Percent_Identity=21.2189616252822, Blast_Score=89, Evalue=4e-19,
Organism=Drosophila melanogaster, GI19920686, Length=380, Percent_Identity=22.8947368421053, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43954; Mature: 43822

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATAAAQGDRSTRIAIVLVTLLFLGNALNYVDRQVLALLKPTLEAEFGWSDSDYAHLGST
CCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCC
FQIAAAGALLGVGWFVDRLGVRWAYAIAISVWSLAGMAHALAQSVQQFVAARVVLAVGES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VSTPAGIKTAATYLPVRQRNMAIGLINTAPNIGAIVTPLLIPPLALAFGWKAAFIATGAL
CCCCCCHHHHHHHCCHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GFVWLAFWLPAMRKMRPLGDLPERAKVAWRPLLRDRRTWAVVGAKFCTDCVWWFVLFWMP
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
DFFSREFGMSQGALGLPIAIVFTLAALGAVTSGALYPILLGRGFSVDRARKLSMFVFALA
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHH
VLVMPLAMYTTSPWVAALCVGLGLFAHQGFSTNIFGMTADIIPPLRVATVIALGAVAGNL
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHCCC
SGTAIIEFAGWSLGNGLGYGPLFIICSLAYLTALLVIHLIVPRLELAESRA
CCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ATAAAQGDRSTRIAIVLVTLLFLGNALNYVDRQVLALLKPTLEAEFGWSDSDYAHLGST
CCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCC
FQIAAAGALLGVGWFVDRLGVRWAYAIAISVWSLAGMAHALAQSVQQFVAARVVLAVGES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VSTPAGIKTAATYLPVRQRNMAIGLINTAPNIGAIVTPLLIPPLALAFGWKAAFIATGAL
CCCCCCHHHHHHHCCHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GFVWLAFWLPAMRKMRPLGDLPERAKVAWRPLLRDRRTWAVVGAKFCTDCVWWFVLFWMP
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
DFFSREFGMSQGALGLPIAIVFTLAALGAVTSGALYPILLGRGFSVDRARKLSMFVFALA
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHH
VLVMPLAMYTTSPWVAALCVGLGLFAHQGFSTNIFGMTADIIPPLRVATVIALGAVAGNL
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHCCC
SGTAIIEFAGWSLGNGLGYGPLFIICSLAYLTALLVIHLIVPRLELAESRA
CCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: galacturonate [Periplasm]; Proton [Periplasm]; glucuronate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + galacturonate [Periplasm] = galacturonate [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + glucuronate [Periplasm] = Proton [Cytoplasm] + glucuronate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]