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The map label for this gene is galE [H]

Identifier: 103487044

GI number: 103487044

Start: 1623680

End: 1624696

Strand: Direct

Name: galE [H]

Synonym: Sala_1559

Alternate gene names: 103487044

Gene position: 1623680-1624696 (Clockwise)

Preceding gene: 103487038

Following gene: 103487052

Centisome position: 48.54

GC content: 65.49

Gene sequence:

>1017_bases
ATGAACATCTTTCTCACCGGCGGCGCCGGATATATCGGCAGTCACGTCGCGGCGACGCTGGCGGCGGCCGGCCACCGGGT
GACCTGTTTCGACAATCTGTCGAACAGCGACGCGGCGGTGATCGACCGGCTGGAGGCGATCACCGGCGCGGTGATCCCGC
TGGTCGTCGGCGACATCCGCGACGGCGACGCGCTGCGCCGCGCGATGCGCGGCCACGCGATCGAGGCGGTGATCCATTTT
GCGGGGCTGAAGGCGGTCGGCGAATCGGTCGCCGAGCCGATCCGCTATTATGACAATAATGTGCGCGGCACGCTGTCGCT
GATCGAAGCGATGATCGACTGTCATGTGAAACGCCTCGTCTTTTCGTCGAGCGCCACCGTCTATGGCGAGCCGCAATATC
TTCCGCTCGACGAGGATCACCCGACTGCGGCAACCAATCCCTATGGCCGCACCAAGCTGATGATCGAGGAGATGCTGGCT
GACATTGCCGCCGCGGACCCCGAATGGCGGATCGCCATCCTGCGTTATTTCAATCCCGTCGGCGCGCACGACAGCGGGCT
GATCGGCGAAAATCCCAATGGCATTCCGAACAATCTGATGCCCTTCATCAGCCGTGTCGCGGCGGGCAAGCTCAAGGAGT
TGTCGGTGTTCGGCGACGATTATGACACGCCCGACGGTACCGGGGTGCGCGATTATATCCATGTCGTCGATCTGGCGGCC
GGACACGCGGCGGCGCTGGACGCTATTGCCGGCGCCGACCGGCCGCTGTCGATCTGGAACCTCGGCACCGGTCAGGGCTA
TTCGGTGTTCGACATCATCCGCGCGTTCGAGCGCGTGAACGGCGTCGCCATCCCCTATCGCATCGCGCCGCGCCGCGCGG
GCGATGTCGCGAGTTGCTTCGCGAGCCCCGAGCGCGCCGCGCGCGAGCTTGGCTGGGCGGCCGAGCGCGATCTGGATGCC
ATGTGCGCGTCGAGCTGGCGCTTCGAGCGGATGCTCGCGACACGCAACGCCGAGTAA

Upstream 100 bases:

>100_bases
TCGCCGGAATGACGCGATTGAGGTTTCTCCCGATCGAGCCCGGACGCGCGCCGGATGCATAGGGACGGTCGCGAACGGGA
CGGCAGGGCAAGGGCAGGCG

Downstream 100 bases:

>100_bases
GTCCTGACCTCCGGGCCGCTACCGCAGCCACCCCGCCGTCTGGGCGAGCACCCAGATCCCGATCACAAGAAACAGCGCGG
CGGCGATCCGGCGCACCCTG

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MNIFLTGGAGYIGSHVAATLAAAGHRVTCFDNLSNSDAAVIDRLEAITGAVIPLVVGDIRDGDALRRAMRGHAIEAVIHF
AGLKAVGESVAEPIRYYDNNVRGTLSLIEAMIDCHVKRLVFSSSATVYGEPQYLPLDEDHPTAATNPYGRTKLMIEEMLA
DIAAADPEWRIAILRYFNPVGAHDSGLIGENPNGIPNNLMPFISRVAAGKLKELSVFGDDYDTPDGTGVRDYIHVVDLAA
GHAAALDAIAGADRPLSIWNLGTGQGYSVFDIIRAFERVNGVAIPYRIAPRRAGDVASCFASPERAARELGWAAERDLDA
MCASSWRFERMLATRNAE

Sequences:

>Translated_338_residues
MNIFLTGGAGYIGSHVAATLAAAGHRVTCFDNLSNSDAAVIDRLEAITGAVIPLVVGDIRDGDALRRAMRGHAIEAVIHF
AGLKAVGESVAEPIRYYDNNVRGTLSLIEAMIDCHVKRLVFSSSATVYGEPQYLPLDEDHPTAATNPYGRTKLMIEEMLA
DIAAADPEWRIAILRYFNPVGAHDSGLIGENPNGIPNNLMPFISRVAAGKLKELSVFGDDYDTPDGTGVRDYIHVVDLAA
GHAAALDAIAGADRPLSIWNLGTGQGYSVFDIIRAFERVNGVAIPYRIAPRRAGDVASCFASPERAARELGWAAERDLDA
MCASSWRFERMLATRNAE
>Mature_338_residues
MNIFLTGGAGYIGSHVAATLAAAGHRVTCFDNLSNSDAAVIDRLEAITGAVIPLVVGDIRDGDALRRAMRGHAIEAVIHF
AGLKAVGESVAEPIRYYDNNVRGTLSLIEAMIDCHVKRLVFSSSATVYGEPQYLPLDEDHPTAATNPYGRTKLMIEEMLA
DIAAADPEWRIAILRYFNPVGAHDSGLIGENPNGIPNNLMPFISRVAAGKLKELSVFGDDYDTPDGTGVRDYIHVVDLAA
GHAAALDAIAGADRPLSIWNLGTGQGYSVFDIIRAFERVNGVAIPYRIAPRRAGDVASCFASPERAARELGWAAERDLDA
MCASSWRFERMLATRNAE

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=337, Percent_Identity=53.4124629080119, Blast_Score=364, Evalue=1e-101,
Organism=Homo sapiens, GI56118217, Length=337, Percent_Identity=53.4124629080119, Blast_Score=364, Evalue=1e-101,
Organism=Homo sapiens, GI189083684, Length=337, Percent_Identity=53.4124629080119, Blast_Score=364, Evalue=1e-101,
Organism=Homo sapiens, GI7657641, Length=276, Percent_Identity=24.6376811594203, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1786974, Length=331, Percent_Identity=51.0574018126888, Blast_Score=345, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI71982035, Length=347, Percent_Identity=48.7031700288184, Blast_Score=343, Evalue=7e-95,
Organism=Caenorhabditis elegans, GI71982038, Length=349, Percent_Identity=48.4240687679083, Blast_Score=343, Evalue=1e-94,
Organism=Saccharomyces cerevisiae, GI6319493, Length=334, Percent_Identity=48.8023952095808, Blast_Score=338, Evalue=8e-94,
Organism=Drosophila melanogaster, GI19923002, Length=335, Percent_Identity=50.7462686567164, Blast_Score=356, Evalue=2e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36367; Mature: 36367

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIFLTGGAGYIGSHVAATLAAAGHRVTCFDNLSNSDAAVIDRLEAITGAVIPLVVGDIR
CEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
DGDALRRAMRGHAIEAVIHFAGLKAVGESVAEPIRYYDNNVRGTLSLIEAMIDCHVKRLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
FSSSATVYGEPQYLPLDEDHPTAATNPYGRTKLMIEEMLADIAAADPEWRIAILRYFNPV
HCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEHEECCCCC
GAHDSGLIGENPNGIPNNLMPFISRVAAGKLKELSVFGDDYDTPDGTGVRDYIHVVDLAA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHEEEEECCCCCCCCCCCHHHHHHHHHHHC
GHAAALDAIAGADRPLSIWNLGTGQGYSVFDIIRAFERVNGVAIPYRIAPRRAGDVASCF
CHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHH
ASPERAARELGWAAERDLDAMCASSWRFERMLATRNAE
CCHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNIFLTGGAGYIGSHVAATLAAAGHRVTCFDNLSNSDAAVIDRLEAITGAVIPLVVGDIR
CEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
DGDALRRAMRGHAIEAVIHFAGLKAVGESVAEPIRYYDNNVRGTLSLIEAMIDCHVKRLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
FSSSATVYGEPQYLPLDEDHPTAATNPYGRTKLMIEEMLADIAAADPEWRIAILRYFNPV
HCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEHEECCCCC
GAHDSGLIGENPNGIPNNLMPFISRVAAGKLKELSVFGDDYDTPDGTGVRDYIHVVDLAA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHEEEEECCCCCCCCCCCHHHHHHHHHHHC
GHAAALDAIAGADRPLSIWNLGTGQGYSVFDIIRAFERVNGVAIPYRIAPRRAGDVASCF
CHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHH
ASPERAARELGWAAERDLDAMCASSWRFERMLATRNAE
CCHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]