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The map label for this gene is acr1 [H]

Identifier: 103487027

GI number: 103487027

Start: 1609040

End: 1609774

Strand: Direct

Name: acr1 [H]

Synonym: Sala_1542

Alternate gene names: 103487027

Gene position: 1609040-1609774 (Clockwise)

Preceding gene: 103487026

Following gene: 103487028

Centisome position: 48.1

GC content: 66.26

Gene sequence:

>735_bases
ATGGTTACAAGGTCTGAAGAACTGGCGGGGCAGATCGCGCTCGTCACCGGGGCAAGCCGTGGTATCGGCGCCGCAATCGC
CGAATCGCTGGCCGCACGCGGCGCGCATGTCGTGATCACCGCCCGCACCGCCGGCGGGCTCGAGGAACTTGAGGACCGCA
TCCACGCCGCAGGGGGCAGCGCGACGATCGCGCCGCTTGATCTGACCGACGGCGACAGCATCGCCCGCCTCGCCAGCGCG
ATGGCCGAACGCTGGCAGCATCTCGACATGCTCGTGCTCAACGCCGCGATGCTCGGTACGCTCACCCCTGTCGCGGCGAT
CGACGGCAAGGAATTCAACAGGACGCTGACGCTCAACCTGATCGCGCAGCAGGCGCTGATCGCCAATTTCGACCCGCTGC
TTCGCCGTGCCGCGAACGGTCGGCTGCTTGCCCTGTCCACCAGCGTCGCGCGCACCCCGCGCGCCTATTGGGGCGCCTAT
GCCGCGTCGAAGGCCGCCTTCGAGGTGCTTGTTACCAGCTATGGCGCGGAAATGCGCAATATCTCCGGCGTTCGCACCGC
CATTCTCGATCCGGGCCCCACGCGCACGCAGATGCGCGCGCGCGCCTATCCCGGCGAAGATCCGCAGAGCATCAAGGAAC
CAGCCGCGGTCGGCGAATATGTCGCCGACCTGATGGTGCAGGGCTTTGACAGCACCGCCTTCCATGCTTTGCCCAAGGTG
ATGGAAAAAGCTTAA

Upstream 100 bases:

>100_bases
GCCTGCTTCACCGGCGACTATCCGACCACGCTGACCGACTTCGACGAGCATGGGCTGGAGGATCAATTTTCGCTGCTTGC
CGAACGGGTTGTCTGACATA

Downstream 100 bases:

>100_bases
CGCCATCTTTGCATTCCTGCGCTAAGACACGCGCAAAATCGGGTTTGCGAGGGCGTGGAATGACCAGGACTATCTTGCGA
TCGGCGATGGCTGCGGCGAT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MVTRSEELAGQIALVTGASRGIGAAIAESLAARGAHVVITARTAGGLEELEDRIHAAGGSATIAPLDLTDGDSIARLASA
MAERWQHLDMLVLNAAMLGTLTPVAAIDGKEFNRTLTLNLIAQQALIANFDPLLRRAANGRLLALSTSVARTPRAYWGAY
AASKAAFEVLVTSYGAEMRNISGVRTAILDPGPTRTQMRARAYPGEDPQSIKEPAAVGEYVADLMVQGFDSTAFHALPKV
MEKA

Sequences:

>Translated_244_residues
MVTRSEELAGQIALVTGASRGIGAAIAESLAARGAHVVITARTAGGLEELEDRIHAAGGSATIAPLDLTDGDSIARLASA
MAERWQHLDMLVLNAAMLGTLTPVAAIDGKEFNRTLTLNLIAQQALIANFDPLLRRAANGRLLALSTSVARTPRAYWGAY
AASKAAFEVLVTSYGAEMRNISGVRTAILDPGPTRTQMRARAYPGEDPQSIKEPAAVGEYVADLMVQGFDSTAFHALPKV
MEKA
>Mature_244_residues
MVTRSEELAGQIALVTGASRGIGAAIAESLAARGAHVVITARTAGGLEELEDRIHAAGGSATIAPLDLTDGDSIARLASA
MAERWQHLDMLVLNAAMLGTLTPVAAIDGKEFNRTLTLNLIAQQALIANFDPLLRRAANGRLLALSTSVARTPRAYWGAY
AASKAAFEVLVTSYGAEMRNISGVRTAILDPGPTRTQMRARAYPGEDPQSIKEPAAVGEYVADLMVQGFDSTAFHALPKV
MEKA

Specific function: Catalyzes the NADPH-dependent reduction of long chain acyl-CoA to the corresponding aldehyde [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=215, Percent_Identity=28.3720930232558, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI7657478, Length=215, Percent_Identity=26.5116279069767, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI109715829, Length=216, Percent_Identity=28.7037037037037, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI20149619, Length=204, Percent_Identity=26.4705882352941, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI32455239, Length=202, Percent_Identity=28.7128712871287, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI5031765, Length=202, Percent_Identity=28.7128712871287, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI7706318, Length=212, Percent_Identity=25.4716981132075, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787526, Length=217, Percent_Identity=34.5622119815668, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1786701, Length=220, Percent_Identity=24.5454545454545, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787335, Length=189, Percent_Identity=32.2751322751323, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI2367175, Length=197, Percent_Identity=30.9644670050761, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786812, Length=203, Percent_Identity=27.0935960591133, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082100, Length=212, Percent_Identity=31.1320754716981, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=198, Percent_Identity=26.2626262626263, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=209, Percent_Identity=28.7081339712919, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=198, Percent_Identity=25.7575757575758, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322227, Length=200, Percent_Identity=29.5, Blast_Score=76, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6322226, Length=204, Percent_Identity=26.9607843137255, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=231, Percent_Identity=27.2727272727273, Blast_Score=62, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21355319, Length=201, Percent_Identity=27.363184079602, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21358495, Length=204, Percent_Identity=25.4901960784314, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI23397609, Length=193, Percent_Identity=32.1243523316062, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28571526, Length=197, Percent_Identity=31.4720812182741, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357673, Length=189, Percent_Identity=26.984126984127, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25682; Mature: 25682

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTRSEELAGQIALVTGASRGIGAAIAESLAARGAHVVITARTAGGLEELEDRIHAAGGS
CCCCCHHHHCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCC
ATIAPLDLTDGDSIARLASAMAERWQHLDMLVLNAAMLGTLTPVAAIDGKEFNRTLTLNL
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCEEEHHH
IAQQALIANFDPLLRRAANGRLLALSTSVARTPRAYWGAYAASKAAFEVLVTSYGAEMRN
HHHHHHHHCHHHHHHHHCCCCEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHH
ISGVRTAILDPGPTRTQMRARAYPGEDPQSIKEPAAVGEYVADLMVQGFDSTAFHALPKV
CCHHHHEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
MEKA
HHCC
>Mature Secondary Structure
MVTRSEELAGQIALVTGASRGIGAAIAESLAARGAHVVITARTAGGLEELEDRIHAAGGS
CCCCCHHHHCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCC
ATIAPLDLTDGDSIARLASAMAERWQHLDMLVLNAAMLGTLTPVAAIDGKEFNRTLTLNL
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCEEEHHH
IAQQALIANFDPLLRRAANGRLLALSTSVARTPRAYWGAYAASKAAFEVLVTSYGAEMRN
HHHHHHHHCHHHHHHHHCCCCEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHH
ISGVRTAILDPGPTRTQMRARAYPGEDPQSIKEPAAVGEYVADLMVQGFDSTAFHALPKV
CCHHHHEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
MEKA
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA