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The map label for this gene is citE [H]

Identifier: 103487020

GI number: 103487020

Start: 1601679

End: 1602530

Strand: Direct

Name: citE [H]

Synonym: Sala_1535

Alternate gene names: 103487020

Gene position: 1601679-1602530 (Clockwise)

Preceding gene: 103487019

Following gene: 103487026

Centisome position: 47.88

GC content: 68.54

Gene sequence:

>852_bases
ATGCGCCTCCGCTCGCTTCTCTTCGTCCCCGGCGACCGGCCCGAACGCTTTGCCAAGGCGGCGGCGTCGGGTGCCGATGC
CATCATCCTCGACCTGGAGGATTCGGTGTCGCCCGCGAACAAGGACGCGGCGCGCCACGCCGTCGCCGAATATCTGTCGG
GGACGCGCGAAGTCGTGACGCTGGTGCGCGTCAATCCGCTCGACGGGCATATGACCGCCGCCGATGTCACCGCGGTGATC
GGCGCGCGCCCCGATGCGATCATGCTGCCCAAGGCCGAGGGCGCGCCGAGCATCCAGCAACTCGACACGATCCTGCGGAG
CGAAACGGCGGATGACGCTTCGCTGCCTGCGATCCTGCCGATTGCCACCGAGACGCCCGCGGCAATCTTCACGCTTGGCA
GCTACCGCGAAGTGAAAGACCGCCTGCTCGGCCTGACCTGGGGCGCCGAGGATCTGCCGGCCGCGATCGGCGCGACGACG
AGCCGCGAGGCGGACGGACGCTATACCCAGCCTTATGAAGTCGCGCGCGCGCTGACACTCTTTGCCGCTCATGCCGCAGG
CGTCGCGGCGATCGACACGGTGTTCCCCGCGATCAAGGATGCCGATGGCCTCGCCGCCTATGCCGCTCGCGCGCGGCGCG
ACGGCTTTACCGGCATGATGGCGATCCACCCGTCGCAGGTCGAACCGATCAATGCCGCCTTCACCCCCAGTGCCGAGGAA
GCGGCGCGCGCGCAGGCGATCGTCGACGCCTTCGCCGCCAATCCCGGCGCCGGAGTGCTCCAGGTCGACGGCAAGATGGT
CGACGCGCCGCATCTGAAACAGGCCCGGCATATATTGTCGCTGGCGAACTGA

Upstream 100 bases:

>100_bases
ATGCAGGTATCGTCACCTTCCTGCACCGGGCGATCAATCAGCGGGGCGAAATCGTCTGTCAGTGTGAACGCTCCGCGCTC
ATCAAAAGGAAGGACGCCTG

Downstream 100 bases:

>100_bases
CCCCCGTCATCCTGGCGAAGGCCGGGATCTCGCCGGTGTGTCAGAGCGCGATGTTGAGATCCCGGCCTTCGCCGGGATGA
CGGATGGGAGCGGTTAGCGC

Product: Citryl-CoA lyase

Products: NA

Alternate protein names: Citrase beta chain; Citrate (pro-3S)-lyase subunit beta; Citryl-CoA lyase subunit [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MRLRSLLFVPGDRPERFAKAAASGADAIILDLEDSVSPANKDAARHAVAEYLSGTREVVTLVRVNPLDGHMTAADVTAVI
GARPDAIMLPKAEGAPSIQQLDTILRSETADDASLPAILPIATETPAAIFTLGSYREVKDRLLGLTWGAEDLPAAIGATT
SREADGRYTQPYEVARALTLFAAHAAGVAAIDTVFPAIKDADGLAAYAARARRDGFTGMMAIHPSQVEPINAAFTPSAEE
AARAQAIVDAFAANPGAGVLQVDGKMVDAPHLKQARHILSLAN

Sequences:

>Translated_283_residues
MRLRSLLFVPGDRPERFAKAAASGADAIILDLEDSVSPANKDAARHAVAEYLSGTREVVTLVRVNPLDGHMTAADVTAVI
GARPDAIMLPKAEGAPSIQQLDTILRSETADDASLPAILPIATETPAAIFTLGSYREVKDRLLGLTWGAEDLPAAIGATT
SREADGRYTQPYEVARALTLFAAHAAGVAAIDTVFPAIKDADGLAAYAARARRDGFTGMMAIHPSQVEPINAAFTPSAEE
AARAQAIVDAFAANPGAGVLQVDGKMVDAPHLKQARHILSLAN
>Mature_283_residues
MRLRSLLFVPGDRPERFAKAAASGADAIILDLEDSVSPANKDAARHAVAEYLSGTREVVTLVRVNPLDGHMTAADVTAVI
GARPDAIMLPKAEGAPSIQQLDTILRSETADDASLPAILPIATETPAAIFTLGSYREVKDRLLGLTWGAEDLPAAIGATT
SREADGRYTQPYEVARALTLFAAHAAGVAAIDTVFPAIKDADGLAAYAARARRDGFTGMMAIHPSQVEPINAAFTPSAEE
AARAQAIVDAFAANPGAGVLQVDGKMVDAPHLKQARHILSLAN

Specific function: Represents a citryl-ACP lyase [H]

COG id: COG2301

COG function: function code G; Citrate lyase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily [H]

Homologues:

Organism=Homo sapiens, GI45545437, Length=297, Percent_Identity=30.6397306397306, Blast_Score=119, Evalue=2e-27,
Organism=Escherichia coli, GI87081764, Length=285, Percent_Identity=34.3859649122807, Blast_Score=120, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17557458, Length=299, Percent_Identity=31.438127090301, Blast_Score=107, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR011206
- InterPro:   IPR006475
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: =4.1.3.6; =4.1.3.34 [H]

Molecular weight: Translated: 29608; Mature: 29608

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLRSLLFVPGDRPERFAKAAASGADAIILDLEDSVSPANKDAARHAVAEYLSGTREVVT
CCCCCEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCHHHEEE
LVRVNPLDGHMTAADVTAVIGARPDAIMLPKAEGAPSIQQLDTILRSETADDASLPAILP
EEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCEEEE
IATETPAAIFTLGSYREVKDRLLGLTWGAEDLPAAIGATTSREADGRYTQPYEVARALTL
ECCCCCCEEEECCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
FAAHAAGVAAIDTVFPAIKDADGLAAYAARARRDGFTGMMAIHPSQVEPINAAFTPSAEE
HHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHH
AARAQAIVDAFAANPGAGVLQVDGKMVDAPHLKQARHILSLAN
HHHHHHHHHHHHCCCCCCEEEECCEEECCHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLRSLLFVPGDRPERFAKAAASGADAIILDLEDSVSPANKDAARHAVAEYLSGTREVVT
CCCCCEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCHHHEEE
LVRVNPLDGHMTAADVTAVIGARPDAIMLPKAEGAPSIQQLDTILRSETADDASLPAILP
EEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCEEEE
IATETPAAIFTLGSYREVKDRLLGLTWGAEDLPAAIGATTSREADGRYTQPYEVARALTL
ECCCCCCEEEECCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
FAAHAAGVAAIDTVFPAIKDADGLAAYAARARRDGFTGMMAIHPSQVEPINAAFTPSAEE
HHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHH
AARAQAIVDAFAANPGAGVLQVDGKMVDAPHLKQARHILSLAN
HHHHHHHHHHHHCCCCCCEEEECCEEECCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9457870 [H]