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The map label for this gene is hfaC [H]

Identifier: 103487009

GI number: 103487009

Start: 1589271

End: 1591052

Strand: Direct

Name: hfaC [H]

Synonym: Sala_1524

Alternate gene names: 103487009

Gene position: 1589271-1591052 (Clockwise)

Preceding gene: 103487007

Following gene: 103487014

Centisome position: 47.51

GC content: 66.5

Gene sequence:

>1782_bases
ATGGCGGCACCCATTCTTTCATACGAAGGCCTAGGCCTTGTGCAGGGCAGCGGCTGGCTGTTCCAGGATCTCGACATCTA
TATCGGGCCGCGCGATCGACTGGCGCTGATCGGCCGCAACGGTGCGGGCAAGACGACCTTGCTCAAGCTGCTCGCGGGGC
GCATCGAGCCCGACAGGGGCAAGCGGACGATCGTTCCCGGTACGCATGTCGTGATGCTCGAACAGGAACCCGACTTTCGC
CCCTTCGCCACACTGATGGATTTCGCAGCGGCGGGTGCCGACGCCCCTGCCGGGCATGAAGTCGCGGCGATCGCCGACCA
GCTCGGCATCGACATGAGCCGTGCCGCCGCCAGCGCATCGGGCGGCGAGCGCCGCCGCGCCGCGCTGGCGCGCGCGCTGG
CGCAGAATCCCGATGTGCTGCTGCTCGACGAGCCGACCAACCACCTGGATCTCGCGGCAATCGACTGGCTCGAAAGCTGG
CTCGCACGCTATACGGGCGCCTTTGTCGTCATCAGCCACGACCGCACCTTCCTCACCCGTCTGACGCGCCAGACCCTCTG
GCTCGATCGCGGCAGCATCCGCCGCAAGGAAATCGGCTTCGGCGGCTTCGAGGAATGGACCGAGGCGGTTTATGCCGAGG
AAGCGCGCGCCGCGCAGAAACTCGATTCCAAATTGCGGCTCGAGGCGCACTGGCTCGAACGCGGCGTCACCGCGCGCCGC
AAGCGCAATCAGGGTCGTCTTGAAAAACTCAAGGAAATGCGCGCGACCCGCGCCGCGATGATCGGCGGCCCCGGCGTCGC
CAAGCTCGGCCTCGCCAACGACGATGTCCGCTCGAAATCGGTGATCGTTGCCGAGGGGGTGAGCAAGAGCTTCGATGGCC
GCACGATCATCAAGAACCTTGATTTTCGCGTCCAGCGCGGCGACCGCATCGGCATCGTCGGCGCCAATGGCGCGGGCAAA
TCGACGCTGCTCAAGCTGCTCACCGGCGAGCTTCAGCCCGACAGCGGCAGCATCACCCTCGCCCCGACGCTCGACGGCAT
CATTATCGACCAGCAGCGCAGCCTGATGTCGCCCGAAAAGCGCGTGCGCGACGTGCTTGCCGACGGCGGCGACTGGGTCG
AGGTGCGCGGGGTGAAAAAACATGTCCAGGGCTATATGAAAGAGTTTCTCTTCGACCCCGGCGTCGTCGAGGCGAGCGTC
GGCGCGCTGTCGGGCGGCGAACGCTCGCGGCTGCTGCTCGCGCGCGAATTCGCCCGCGAATCGAACCTGCTCGTGCTCGA
CGAGCCGACCAACGACCTCGACCTCGAAACGCTCGACCTGTTGCAGGAAGTGATCGCCGACTATGCCGGCACCGTGCTGC
TCGTCAGCCACGACCGCGATTTCCTCGACCGCACCGTCACGGTGACGCTGGGCCTCGACGGATCGGGCAAGGTCGATATC
GTCGCGGGCGGCTATGCCGACTGGGAAGCGAAACGCACCAGGCCTTCGACCGCCAAAACCAAATCCGCCGCCGCCGAATC
CACGCCGCCACCGCCCCCGCGGGCGCGCCGCAAACTGTCCTACAAGGACCAGCGCGACTACGACCTTCTCCCCGCCCGGA
TCGAGGCGATCGAGGCCGAGATAGCCGACATCGAGGCCGAGTTGTCCGACGGCGCGCTGTTCACGCGCGACAACGCCCGC
TTCAAGGCGTTGACCGACAAGCTCGACGCGCTCCGCACCGAAAAGGCCGCCGCCGAAGACCGCTGGCTTGCGCTCGCGGA
AGAGGTCGAGGCCCTGCAATAA

Upstream 100 bases:

>100_bases
ATGCTTTCCACCCCGTAACGCAGACGGAGCGGGCGCGTTCCGGCCTTTGCGCGCAGGGCGCTTGCATGATGCTGAACGCG
CCAGTAGCGAGCCGTTCATC

Downstream 100 bases:

>100_bases
GCGGGGCCGGTCCCGACCGAAACGAAACGACCATTTCGGGGTGGGGAGCGGACTGTCGCCTTACTGTTGCCCCCCGGCTT
TCGCCGGGGCACGGCTGCTG

Product: ABC transporter related

Products: NA

Alternate protein names: Protein HfaC [H]

Number of amino acids: Translated: 593; Mature: 592

Protein sequence:

>593_residues
MAAPILSYEGLGLVQGSGWLFQDLDIYIGPRDRLALIGRNGAGKTTLLKLLAGRIEPDRGKRTIVPGTHVVMLEQEPDFR
PFATLMDFAAAGADAPAGHEVAAIADQLGIDMSRAAASASGGERRRAALARALAQNPDVLLLDEPTNHLDLAAIDWLESW
LARYTGAFVVISHDRTFLTRLTRQTLWLDRGSIRRKEIGFGGFEEWTEAVYAEEARAAQKLDSKLRLEAHWLERGVTARR
KRNQGRLEKLKEMRATRAAMIGGPGVAKLGLANDDVRSKSVIVAEGVSKSFDGRTIIKNLDFRVQRGDRIGIVGANGAGK
STLLKLLTGELQPDSGSITLAPTLDGIIIDQQRSLMSPEKRVRDVLADGGDWVEVRGVKKHVQGYMKEFLFDPGVVEASV
GALSGGERSRLLLAREFARESNLLVLDEPTNDLDLETLDLLQEVIADYAGTVLLVSHDRDFLDRTVTVTLGLDGSGKVDI
VAGGYADWEAKRTRPSTAKTKSAAAESTPPPPPRARRKLSYKDQRDYDLLPARIEAIEAEIADIEAELSDGALFTRDNAR
FKALTDKLDALRTEKAAAEDRWLALAEEVEALQ

Sequences:

>Translated_593_residues
MAAPILSYEGLGLVQGSGWLFQDLDIYIGPRDRLALIGRNGAGKTTLLKLLAGRIEPDRGKRTIVPGTHVVMLEQEPDFR
PFATLMDFAAAGADAPAGHEVAAIADQLGIDMSRAAASASGGERRRAALARALAQNPDVLLLDEPTNHLDLAAIDWLESW
LARYTGAFVVISHDRTFLTRLTRQTLWLDRGSIRRKEIGFGGFEEWTEAVYAEEARAAQKLDSKLRLEAHWLERGVTARR
KRNQGRLEKLKEMRATRAAMIGGPGVAKLGLANDDVRSKSVIVAEGVSKSFDGRTIIKNLDFRVQRGDRIGIVGANGAGK
STLLKLLTGELQPDSGSITLAPTLDGIIIDQQRSLMSPEKRVRDVLADGGDWVEVRGVKKHVQGYMKEFLFDPGVVEASV
GALSGGERSRLLLAREFARESNLLVLDEPTNDLDLETLDLLQEVIADYAGTVLLVSHDRDFLDRTVTVTLGLDGSGKVDI
VAGGYADWEAKRTRPSTAKTKSAAAESTPPPPPRARRKLSYKDQRDYDLLPARIEAIEAEIADIEAELSDGALFTRDNAR
FKALTDKLDALRTEKAAAEDRWLALAEEVEALQ
>Mature_592_residues
AAPILSYEGLGLVQGSGWLFQDLDIYIGPRDRLALIGRNGAGKTTLLKLLAGRIEPDRGKRTIVPGTHVVMLEQEPDFRP
FATLMDFAAAGADAPAGHEVAAIADQLGIDMSRAAASASGGERRRAALARALAQNPDVLLLDEPTNHLDLAAIDWLESWL
ARYTGAFVVISHDRTFLTRLTRQTLWLDRGSIRRKEIGFGGFEEWTEAVYAEEARAAQKLDSKLRLEAHWLERGVTARRK
RNQGRLEKLKEMRATRAAMIGGPGVAKLGLANDDVRSKSVIVAEGVSKSFDGRTIIKNLDFRVQRGDRIGIVGANGAGKS
TLLKLLTGELQPDSGSITLAPTLDGIIIDQQRSLMSPEKRVRDVLADGGDWVEVRGVKKHVQGYMKEFLFDPGVVEASVG
ALSGGERSRLLLAREFARESNLLVLDEPTNDLDLETLDLLQEVIADYAGTVLLVSHDRDFLDRTVTVTLGLDGSGKVDIV
AGGYADWEAKRTRPSTAKTKSAAAESTPPPPPRARRKLSYKDQRDYDLLPARIEAIEAEIADIEAELSDGALFTRDNARF
KALTDKLDALRTEKAAAEDRWLALAEEVEALQ

Specific function: Involved in attachment of the holdfast to the cell. The holdfast is a structure that allows the bacteria to firmly adhere to surfaces [H]

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI10947135, Length=528, Percent_Identity=28.030303030303, Blast_Score=152, Evalue=8e-37,
Organism=Homo sapiens, GI69354671, Length=528, Percent_Identity=28.030303030303, Blast_Score=152, Evalue=8e-37,
Organism=Homo sapiens, GI148612853, Length=520, Percent_Identity=29.6153846153846, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI27881506, Length=503, Percent_Identity=27.037773359841, Blast_Score=126, Evalue=7e-29,
Organism=Homo sapiens, GI10947137, Length=503, Percent_Identity=27.037773359841, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI90421313, Length=151, Percent_Identity=29.8013245033113, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1787182, Length=635, Percent_Identity=37.4803149606299, Blast_Score=368, Evalue=1e-103,
Organism=Escherichia coli, GI2367384, Length=526, Percent_Identity=33.0798479087452, Blast_Score=264, Evalue=1e-71,
Organism=Escherichia coli, GI1789751, Length=639, Percent_Identity=28.9514866979656, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1787041, Length=525, Percent_Identity=28.1904761904762, Blast_Score=206, Evalue=4e-54,
Organism=Escherichia coli, GI1787758, Length=202, Percent_Identity=29.2079207920792, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87081791, Length=197, Percent_Identity=31.4720812182741, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786253, Length=226, Percent_Identity=29.646017699115, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788225, Length=252, Percent_Identity=27.7777777777778, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788165, Length=217, Percent_Identity=29.4930875576037, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787164, Length=188, Percent_Identity=31.9148936170213, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787792, Length=229, Percent_Identity=29.2576419213974, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI87081834, Length=195, Percent_Identity=30.2564102564103, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI48995001, Length=213, Percent_Identity=28.6384976525822, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788506, Length=192, Percent_Identity=28.125, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1786563, Length=182, Percent_Identity=29.1208791208791, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87082267, Length=192, Percent_Identity=30.7291666666667, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787029, Length=213, Percent_Identity=26.7605633802817, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789891, Length=218, Percent_Identity=25.6880733944954, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1789672, Length=241, Percent_Identity=24.896265560166, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787712, Length=193, Percent_Identity=27.979274611399, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789032, Length=217, Percent_Identity=29.9539170506912, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788761, Length=208, Percent_Identity=31.25, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788210, Length=194, Percent_Identity=29.3814432989691, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI87081709, Length=201, Percent_Identity=27.363184079602, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=546, Percent_Identity=26.9230769230769, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17555318, Length=493, Percent_Identity=28.3975659229209, Blast_Score=139, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17553372, Length=369, Percent_Identity=30.8943089430894, Blast_Score=128, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17533971, Length=180, Percent_Identity=28.8888888888889, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI212646699, Length=182, Percent_Identity=31.3186813186813, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI115533592, Length=195, Percent_Identity=31.2820512820513, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320874, Length=517, Percent_Identity=28.2398452611219, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6321121, Length=420, Percent_Identity=29.2857142857143, Blast_Score=144, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6325030, Length=346, Percent_Identity=29.7687861271676, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6323278, Length=338, Percent_Identity=28.4023668639053, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6324314, Length=342, Percent_Identity=27.1929824561404, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24641342, Length=541, Percent_Identity=27.5415896487985, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24666836, Length=547, Percent_Identity=30.7129798903108, Blast_Score=172, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24642252, Length=505, Percent_Identity=29.9009900990099, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI18859989, Length=505, Percent_Identity=29.9009900990099, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI221500365, Length=168, Percent_Identity=32.7380952380952, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI116007184, Length=168, Percent_Identity=32.7380952380952, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17136662, Length=186, Percent_Identity=30.1075268817204, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28574259, Length=173, Percent_Identity=29.4797687861272, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281363262, Length=204, Percent_Identity=27.4509803921569, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24666092, Length=207, Percent_Identity=29.951690821256, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24653245, Length=204, Percent_Identity=27.4509803921569, Blast_Score=66, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR007406 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 64824; Mature: 64693

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPILSYEGLGLVQGSGWLFQDLDIYIGPRDRLALIGRNGAGKTTLLKLLAGRIEPDRG
CCCCCCCCCCCEEEECCCCEEEECEEEECCCCCEEEEECCCCCHHHHHHHHHHCCCCCCC
KRTIVPGTHVVMLEQEPDFRPFATLMDFAAAGADAPAGHEVAAIADQLGIDMSRAAASAS
CEEECCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHCCC
GGERRRAALARALAQNPDVLLLDEPTNHLDLAAIDWLESWLARYTGAFVVISHDRTFLTR
CCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCEEEEEECCHHHHHH
LTRQTLWLDRGSIRRKEIGFGGFEEWTEAVYAEEARAAQKLDSKLRLEAHWLERGVTARR
HHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
KRNQGRLEKLKEMRATRAAMIGGPGVAKLGLANDDVRSKSVIVAEGVSKSFDGRTIIKNL
HCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCCEEECCC
DFRVQRGDRIGIVGANGAGKSTLLKLLTGELQPDSGSITLAPTLDGIIIDQQRSLMSPEK
CEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCEEECCHHHHCCHHH
RVRDVLADGGDWVEVRGVKKHVQGYMKEFLFDPGVVEASVGALSGGERSRLLLAREFARE
HHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCHHHHHHHHHHCC
SNLLVLDEPTNDLDLETLDLLQEVIADYAGTVLLVSHDRDFLDRTVTVTLGLDGSGKVDI
CCEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHCCCEEEEEEECCCCCCEEE
VAGGYADWEAKRTRPSTAKTKSAAAESTPPPPPRARRKLSYKDQRDYDLLPARIEAIEAE
EECCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHH
IADIEAELSDGALFTRDNARFKALTDKLDALRTEKAAAEDRWLALAEEVEALQ
HHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AAPILSYEGLGLVQGSGWLFQDLDIYIGPRDRLALIGRNGAGKTTLLKLLAGRIEPDRG
CCCCCCCCCCEEEECCCCEEEECEEEECCCCCEEEEECCCCCHHHHHHHHHHCCCCCCC
KRTIVPGTHVVMLEQEPDFRPFATLMDFAAAGADAPAGHEVAAIADQLGIDMSRAAASAS
CEEECCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHCCC
GGERRRAALARALAQNPDVLLLDEPTNHLDLAAIDWLESWLARYTGAFVVISHDRTFLTR
CCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCEEEEEECCHHHHHH
LTRQTLWLDRGSIRRKEIGFGGFEEWTEAVYAEEARAAQKLDSKLRLEAHWLERGVTARR
HHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
KRNQGRLEKLKEMRATRAAMIGGPGVAKLGLANDDVRSKSVIVAEGVSKSFDGRTIIKNL
HCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCCEEECCC
DFRVQRGDRIGIVGANGAGKSTLLKLLTGELQPDSGSITLAPTLDGIIIDQQRSLMSPEK
CEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCEEECCHHHHCCHHH
RVRDVLADGGDWVEVRGVKKHVQGYMKEFLFDPGVVEASVGALSGGERSRLLLAREFARE
HHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCHHHHHHHHHHCC
SNLLVLDEPTNDLDLETLDLLQEVIADYAGTVLLVSHDRDFLDRTVTVTLGLDGSGKVDI
CCEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHCCCEEEEEEECCCCCCEEE
VAGGYADWEAKRTRPSTAKTKSAAAESTPPPPPRARRKLSYKDQRDYDLLPARIEAIEAE
EECCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHH
IADIEAELSDGALFTRDNARFKALTDKLDALRTEKAAAEDRWLALAEEVEALQ
HHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11259647; 8150261 [H]