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The map label for this gene is glmU [H]

Identifier: 103486856

GI number: 103486856

Start: 1425447

End: 1426814

Strand: Reverse

Name: glmU [H]

Synonym: Sala_1370

Alternate gene names: 103486856

Gene position: 1426814-1425447 (Counterclockwise)

Preceding gene: 103486858

Following gene: 103486855

Centisome position: 42.65

GC content: 66.81

Gene sequence:

>1368_bases
ATGGCAGCGCGCATGAACAACCCGATCGCCGCCATCGTCCTTGCCGCGGGCAAGGGCACCCGCATGAAGTCCGACCTGCA
CAAGGTGCTGCACCCGATCGCCGGGCGGCCGATGCTGCTGCACCTGATGGCGAGCGTCGACGAACTGAGCCCCGCGAAAA
AGGTGGTCGTTGTCGGCGACAAGGCCGATCAGCTCGAAGCGGCGCTGAGCGGCACCGCGGAGCTTGCGGTGCAGGAGCCG
CAGCTCGGCACCGGCCATGCTGTGCGGCAGGCCGAAGCGGCGCTCAGCGGTTTCGATGGCGACGTGCTGATCCTCTATGG
CGATGTGCCCTTTGTGCCTGCGGCGACGATGCGCGCGATGCTCGACCGGCTCGGCGCAAGCGACGCCCCGGCGGTCGTCG
TCCTCGCGTTCGAGCCCGCCGACCCGCTGCAATATGGCCGCGTCATCACCGACGGCGACCGCGTCGTGAAAATGGTCGAG
CATAAGGATGCGACCGACGCGGAGCGTGCGGTGCGGCTCTGCAATTCGGGTCTGATGGCCGCGAGGGCGCGCGATCTGTT
CGCGTTGCTCGCGCGCGTCACCGACGACAATGCGGCGAAGGAGTTTTACCTCGTCGATATCGTCAATATCGCGAACGCCG
ACGGGCGGCTCTGCGCGGTGGTGAAGACCGATCCCGCCGATGTCGGGGGCATCAACAGCCGCGCCGAACTGGCCGCTGCC
GAAGCGCAGTGGCAGGCATTCAGGCGCGAGGAAGCAATGGCGGCCGGCGCGTCGCTGCGCGCCCCCGAAACGGTTTGGTT
TTCGTGGGACACCCAACTCGGTCGCGACGTGACGATCGAACCCAATGTCGTCTTCGGCCCCGGCGTAAAAATCGCCGACG
GCGCGACGATCCGCGCCTTCAGTCATATCGAGGGCGCGACGATCGGCGCTGGCTGCGAGGTCGGGCCCTTTGCGCGGCTG
CGCCCCGGCACGGTGCTCGGCGAAAAGGCGAAGATCGGCAATTTCGTCGAGGTGAAGAAAGCGGTGCTCGGCGCGGGCGC
CAAGGCCAATCATCTGACCTATCTCGGCGATGCGACGGTCGGCGCGGGCGCCAACATCGGTGCGGGGACGATAACCTGCA
ATTATGACGGCTATTTCAAGCACCAGACGCAGATCGGCGAACGCGCCTTCATCGGATCGAACAGCGCGCTCGTCGCGCCG
GTCAAGATCGGCGCCGACGCGATCGTCGCCGCGGGCAGCACGGTGACGCTCGACGTTGGCGACGGCGAATTGCGCATCGT
GCGCGGCGAGCAGCTCGTGAAACCCGGCTGGGCCGACCGCTTCCACGACGCGATGCGCAAGAAGAAGGCGGCGGAACAGA
AGAAATGA

Upstream 100 bases:

>100_bases
ACGAGCGTGCCGTCGAGGTCGAAGCCGACGATCGCAAAAGGAAATCCGTTCATCCCGCGCGCATGGCGCGATGTGCTGGA
AACCGCAATGATTTGCTGGC

Downstream 100 bases:

>100_bases
GCGACCGTTACACCGACCAGCCCTTCCTGCGCTTCGTCGACGCCTGGGTGCTGAAGGTGATCGGGCATCTCGATCCGGCG
ACCGAGGCCTGGTGCAGGGC

Product: bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MAARMNNPIAAIVLAAGKGTRMKSDLHKVLHPIAGRPMLLHLMASVDELSPAKKVVVVGDKADQLEAALSGTAELAVQEP
QLGTGHAVRQAEAALSGFDGDVLILYGDVPFVPAATMRAMLDRLGASDAPAVVVLAFEPADPLQYGRVITDGDRVVKMVE
HKDATDAERAVRLCNSGLMAARARDLFALLARVTDDNAAKEFYLVDIVNIANADGRLCAVVKTDPADVGGINSRAELAAA
EAQWQAFRREEAMAAGASLRAPETVWFSWDTQLGRDVTIEPNVVFGPGVKIADGATIRAFSHIEGATIGAGCEVGPFARL
RPGTVLGEKAKIGNFVEVKKAVLGAGAKANHLTYLGDATVGAGANIGAGTITCNYDGYFKHQTQIGERAFIGSNSALVAP
VKIGADAIVAAGSTVTLDVGDGELRIVRGEQLVKPGWADRFHDAMRKKKAAEQKK

Sequences:

>Translated_455_residues
MAARMNNPIAAIVLAAGKGTRMKSDLHKVLHPIAGRPMLLHLMASVDELSPAKKVVVVGDKADQLEAALSGTAELAVQEP
QLGTGHAVRQAEAALSGFDGDVLILYGDVPFVPAATMRAMLDRLGASDAPAVVVLAFEPADPLQYGRVITDGDRVVKMVE
HKDATDAERAVRLCNSGLMAARARDLFALLARVTDDNAAKEFYLVDIVNIANADGRLCAVVKTDPADVGGINSRAELAAA
EAQWQAFRREEAMAAGASLRAPETVWFSWDTQLGRDVTIEPNVVFGPGVKIADGATIRAFSHIEGATIGAGCEVGPFARL
RPGTVLGEKAKIGNFVEVKKAVLGAGAKANHLTYLGDATVGAGANIGAGTITCNYDGYFKHQTQIGERAFIGSNSALVAP
VKIGADAIVAAGSTVTLDVGDGELRIVRGEQLVKPGWADRFHDAMRKKKAAEQKK
>Mature_454_residues
AARMNNPIAAIVLAAGKGTRMKSDLHKVLHPIAGRPMLLHLMASVDELSPAKKVVVVGDKADQLEAALSGTAELAVQEPQ
LGTGHAVRQAEAALSGFDGDVLILYGDVPFVPAATMRAMLDRLGASDAPAVVVLAFEPADPLQYGRVITDGDRVVKMVEH
KDATDAERAVRLCNSGLMAARARDLFALLARVTDDNAAKEFYLVDIVNIANADGRLCAVVKTDPADVGGINSRAELAAAE
AQWQAFRREEAMAAGASLRAPETVWFSWDTQLGRDVTIEPNVVFGPGVKIADGATIRAFSHIEGATIGAGCEVGPFARLR
PGTVLGEKAKIGNFVEVKKAVLGAGAKANHLTYLGDATVGAGANIGAGTITCNYDGYFKHQTQIGERAFIGSNSALVAPV
KIGADAIVAAGSTVTLDVGDGELRIVRGEQLVKPGWADRFHDAMRKKKAAEQKK

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=452, Percent_Identity=42.9203539823009, Blast_Score=344, Evalue=8e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR018357
- InterPro:   IPR001228
- InterPro:   IPR011004 [H]

Pfam domain/function: PF01128 IspD [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 47800; Mature: 47669

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARMNNPIAAIVLAAGKGTRMKSDLHKVLHPIAGRPMLLHLMASVDELSPAKKVVVVGD
CCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECC
KADQLEAALSGTAELAVQEPQLGTGHAVRQAEAALSGFDGDVLILYGDVPFVPAATMRAM
CHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHH
LDRLGASDAPAVVVLAFEPADPLQYGRVITDGDRVVKMVEHKDATDAERAVRLCNSGLMA
HHHHCCCCCCEEEEEEECCCCCHHHCCEEECHHHHHHHHHCCCCCCHHHHHHHHCCCHHH
ARARDLFALLARVTDDNAAKEFYLVDIVNIANADGRLCAVVKTDPADVGGINSRAELAAA
HHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCEEEEEECCCCCCCCCCCHHHHHHH
EAQWQAFRREEAMAAGASLRAPETVWFSWDTQLGRDVTIEPNVVFGPGVKIADGATIRAF
HHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEEEECCCEEECCCEEEECCCEEEEE
SHIEGATIGAGCEVGPFARLRPGTVLGEKAKIGNFVEVKKAVLGAGAKANHLTYLGDATV
CCCCCCEECCCCCCCCCCCCCCCCEECCHHHCCCHHHHHHHHHCCCCCCCCEEEECCCCC
GAGANIGAGTITCNYDGYFKHQTQIGERAFIGSNSALVAPVKIGADAIVAAGSTVTLDVG
CCCCCCCCCEEEECCCCEEEEHHHCCCEEEECCCCCEEEEEEECCCEEEECCCEEEEEEC
DGELRIVRGEQLVKPGWADRFHDAMRKKKAAEQKK
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AARMNNPIAAIVLAAGKGTRMKSDLHKVLHPIAGRPMLLHLMASVDELSPAKKVVVVGD
CCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECC
KADQLEAALSGTAELAVQEPQLGTGHAVRQAEAALSGFDGDVLILYGDVPFVPAATMRAM
CHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHH
LDRLGASDAPAVVVLAFEPADPLQYGRVITDGDRVVKMVEHKDATDAERAVRLCNSGLMA
HHHHCCCCCCEEEEEEECCCCCHHHCCEEECHHHHHHHHHCCCCCCHHHHHHHHCCCHHH
ARARDLFALLARVTDDNAAKEFYLVDIVNIANADGRLCAVVKTDPADVGGINSRAELAAA
HHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCEEEEEECCCCCCCCCCCHHHHHHH
EAQWQAFRREEAMAAGASLRAPETVWFSWDTQLGRDVTIEPNVVFGPGVKIADGATIRAF
HHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEEEECCCEEECCCEEEECCCEEEEE
SHIEGATIGAGCEVGPFARLRPGTVLGEKAKIGNFVEVKKAVLGAGAKANHLTYLGDATV
CCCCCCEECCCCCCCCCCCCCCCCEECCHHHCCCHHHHHHHHHCCCCCCCCEEEECCCCC
GAGANIGAGTITCNYDGYFKHQTQIGERAFIGSNSALVAPVKIGADAIVAAGSTVTLDVG
CCCCCCCCCEEEECCCCEEEEHHHCCCEEEECCCCCEEEEEEECCCEEEECCCEEEEEEC
DGELRIVRGEQLVKPGWADRFHDAMRKKKAAEQKK
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA