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The map label for this gene is lrp [H]

Identifier: 103486774

GI number: 103486774

Start: 1346471

End: 1346944

Strand: Direct

Name: lrp [H]

Synonym: Sala_1288

Alternate gene names: 103486774

Gene position: 1346471-1346944 (Clockwise)

Preceding gene: 103486771

Following gene: 103486777

Centisome position: 40.25

GC content: 58.86

Gene sequence:

>474_bases
ATGGCGAGTCAGAAATTCGATCAGATTGATCTTCAGATACTGGGCGAATTGCAGAAAAACGGGCGCATGACGAATGTCGA
ACTTGCGCAGATGGTCGGGCTGACGGCCCCTCCCTGCCTGCGCCGTGTGCGCGCGCTGGAGGAAGCCGGGGTCATTCGCT
CCTATCACGCGGACCTCGATGCCGCGAAGCTCGGTTATGGCATCACCGTCTTTGCGATGGTCAGCTTGCGCAGCCAGGCG
GAAGCCGACCTGAAGGCGTTCGAAGATTATGTCGGCGGACTGCCCGAAGTGCGCGAATGCTATATGCTGAACGGCGAAAT
CGACTTTCTTTTGAAGGTCGTGGCCCGCGATTTGCAGAGTTTTCAATCCTTTCTGACCGCGCACCTCACCTCGGCGCCGA
ACGTCACCAGCGTCAAGACGTCGCTCACGATCCGCACCGCGAAACAGCTGGCGGGCGTTCCGGTCGAAATCTGA

Upstream 100 bases:

>100_bases
ACGAAAGTGCCTTAACCATCCGCGTCACATTGTGGGACAATTGCAATCGCCTGAAATATAATTATGGTGATCGCGATTTA
GGAAAGCGGATGTTTCAACG

Downstream 100 bases:

>100_bases
TTCGCCAGGTCATCGAAAAGGGCGCCGTTCCTGGAACGGCGCCCTTTTTTCCGGAATATGCGCTTCGGTCAGCTGGCGGT
GGCCGGCGCGGGTGCGGCAC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MASQKFDQIDLQILGELQKNGRMTNVELAQMVGLTAPPCLRRVRALEEAGVIRSYHADLDAAKLGYGITVFAMVSLRSQA
EADLKAFEDYVGGLPEVRECYMLNGEIDFLLKVVARDLQSFQSFLTAHLTSAPNVTSVKTSLTIRTAKQLAGVPVEI

Sequences:

>Translated_157_residues
MASQKFDQIDLQILGELQKNGRMTNVELAQMVGLTAPPCLRRVRALEEAGVIRSYHADLDAAKLGYGITVFAMVSLRSQA
EADLKAFEDYVGGLPEVRECYMLNGEIDFLLKVVARDLQSFQSFLTAHLTSAPNVTSVKTSLTIRTAKQLAGVPVEI
>Mature_156_residues
ASQKFDQIDLQILGELQKNGRMTNVELAQMVGLTAPPCLRRVRALEEAGVIRSYHADLDAAKLGYGITVFAMVSLRSQAE
ADLKAFEDYVGGLPEVRECYMLNGEIDFLLKVVARDLQSFQSFLTAHLTSAPNVTSVKTSLTIRTAKQLAGVPVEI

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=146, Percent_Identity=37.6712328767123, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI87081742, Length=151, Percent_Identity=29.1390728476821, Blast_Score=87, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17216; Mature: 17085

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASQKFDQIDLQILGELQKNGRMTNVELAQMVGLTAPPCLRRVRALEEAGVIRSYHADLD
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
AAKLGYGITVFAMVSLRSQAEADLKAFEDYVGGLPEVRECYMLNGEIDFLLKVVARDLQS
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
FQSFLTAHLTSAPNVTSVKTSLTIRTAKQLAGVPVEI
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ASQKFDQIDLQILGELQKNGRMTNVELAQMVGLTAPPCLRRVRALEEAGVIRSYHADLD
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
AAKLGYGITVFAMVSLRSQAEADLKAFEDYVGGLPEVRECYMLNGEIDFLLKVVARDLQS
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
FQSFLTAHLTSAPNVTSVKTSLTIRTAKQLAGVPVEI
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157937; 11481430 [H]