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The map label for this gene is fadE12 [H]

Identifier: 103486727

GI number: 103486727

Start: 1289343

End: 1291265

Strand: Direct

Name: fadE12 [H]

Synonym: Sala_1240

Alternate gene names: 103486727

Gene position: 1289343-1291265 (Clockwise)

Preceding gene: 103486725

Following gene: 103486728

Centisome position: 38.54

GC content: 65.16

Gene sequence:

>1923_bases
GTGGACGATCGCCTGATAGGCCGCGCTCAGTTCCAAAATATCGCTCATCCGGCTGTGCTGCGCCTCGCGCAGCAATCGCT
TCGTCAGCCGCAGCGCGCGCGGCGGGTTGCAGACGATCCGCTCGGCAATGGCGATCGCGCGATCGAGCAGCTCCGCATCG
GGCACCACATCGGTAACCAGACCATATTCCTTTGCCTGAGCCGCGTCAAAGCGGTCGCCGGTCAGGAACAGCTCGGCCGC
GCGCGGATAGCCGAGCACCTTTTGCAGCAACCACGCTCCGCCGTCGCCGGGAACGATACCGACCTTGATGAAGCTGCACG
CGAACTTCGCGCTTTCCGCTGCAATGCGAATGTCGCAGGTGCAGGCGAGGTCGCAGCCAAGGCCGATCGCATGGCCGTTG
ATCGCGGCGATCATCGGCACTTCGCAATCCATCAGCGCGCGGATCACCGCCTGTACGCCTTTGCGATAATTGGCTCGCGT
CGAATCGGGCTGATCGAGCACGCCGATTCCGGTGCGCTCCTGCATTCCTTTGAGGTTTCCGCCGGCGCTGAACGCCTTGC
CGCTGCCGGTCAGGATCATCGCGCTGATGCCGCGATCGTCGCCGAGGGTGCGGAGCGTGTCGATGATGTCCTGGCAATCG
TCATGCGTGCCGATCGCATTCATGCTTTCGGGCTTGATCATCGTCAGGATCGCGATCTTGCCCCGCCGCTCGACACTCAA
AAACTCGCCCATCGCCAATTATCCTTTGCTGCTCCGGGGAAGCTATTGCATGGCTGGCGCGACATGCAAGGCTTTGCGCT
CTATCCCTTCGACCCACCCGGCGATGTCGCGGCACTGCGCGCCGAATTGCGGGCATGGCTTGCGGCGAACCAGCCCAGGG
GCGACGTCGTTGCGCGCGCCAATTGCTGGGCGAGTTTCGACACGGATTTCAGCCGCAAGCTGGGCGCGGCGGGTTATGTC
GGGATGACTCTGCCACCACGCTTTGGTGGCGGCGGCCGCCATCCGCTCGAACGCTATGTGGTGATCGAAGAACTGCTTGC
GGCGGGTGCTCCGGTCGGCGCACACTGGATCGCCGACCGCCAGACCGGGCCGCTGATCCTCCGCTACGGCAGCGAGGAAC
AATGTCAGCGCTATCTGCCCGGGATTGCCAGGGGCGAACTATATGCCTGCATCGGACTATCCGAACCCGGCGCCGGGTCG
GATCTCGCCGCGGTGCGAACCACGGCGCGCGAGACTGCCGAGGGCTGGCGGATCAACGGCCAGAAAATCTGGACCACCGG
CGCGCATTTCTCGCACATCATGCTGGCGCTGGTGCGCACCGAAGCGGGGAGCGAGCGTAACGCGGGACTGAGCCAGCTGC
TGATCGACCTCGACACTCCCGGCATTACCATCCGCCCGATCATCGACATGGCGGACCACCATGATTTCAACGAAGTCTTC
TTTGACGATGTGCTCGTGCCGCACGGCGCGTTGGTTGGCGAGCGGGGGCAGGGGTGGAGGCAGGTCACCGCCGAACTCGG
TCTCGAACGATCGGGGCCGGAGCGTTATCTGTCGAGCCACGCGCTGCTCGCCGCGCTGATCGATGCGGCGGGGGTGGACC
CCGACCCGGCGGTGATCGCGCTGATCGGCGAACTCGTCGCCGAAATGTGGACGCTGCGCCAGCTTTCGATGTCGACCGCG
GCCAAGCTCGCGGCGGGCGAGGATCCGATGGTCGAAGCGTCGGTGGTCAAGGAACTGGGCAATGCCTTCGAACAGGATAT
GCCGCGCCGGGTGCAGGCGATCGTCGAGTGCCCGTGGGACGATCCGAGCGACCTTGGCCGGTTGCTGCGCGCCTTGCTGA
TCGCATCGCCCAGTTTCTCGCTGCGCGGCGGCACGCGCGAGGTGATCCGCGGGATCATCGCGCGCGGGCTGGGCCTCAGA
TGA

Upstream 100 bases:

>100_bases
AGAGGCAGGACGCGCTCGGCGAGCATGGTCATTCTCCTGTAAACACGGGGGACCGCTTTTCGACGAACGCGTTGATCGCC
TCGCGGTTATCCGCAGTTTC

Downstream 100 bases:

>100_bases
GCGCGGCGCGCGACATGCTGTGCGACACCGCGCGCGCGGTGTTTGCCGAAGCCGCGGCGGTGGGGATGGCGCCGGTCGAA
GCCGCAGGCTTCGGGCTGCT

Product: acyl-CoA dehydrogenase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 640; Mature: 640

Protein sequence:

>640_residues
MDDRLIGRAQFQNIAHPAVLRLAQQSLRQPQRARRVADDPLGNGDRAIEQLRIGHHIGNQTIFLCLSRVKAVAGQEQLGR
ARIAEHLLQQPRSAVAGNDTDLDEAARELRAFRCNANVAGAGEVAAKADRMAVDRGDHRHFAIHQRADHRLYAFAIIGSR
RIGLIEHADSGALLHSFEVSAGAERLAAAGQDHRADAAIVAEGAERVDDVLAIVMRADRIHAFGLDHRQDRDLAPPLDTQ
KLAHRQLSFAAPGKLLHGWRDMQGFALYPFDPPGDVAALRAELRAWLAANQPRGDVVARANCWASFDTDFSRKLGAAGYV
GMTLPPRFGGGGRHPLERYVVIEELLAAGAPVGAHWIADRQTGPLILRYGSEEQCQRYLPGIARGELYACIGLSEPGAGS
DLAAVRTTARETAEGWRINGQKIWTTGAHFSHIMLALVRTEAGSERNAGLSQLLIDLDTPGITIRPIIDMADHHDFNEVF
FDDVLVPHGALVGERGQGWRQVTAELGLERSGPERYLSSHALLAALIDAAGVDPDPAVIALIGELVAEMWTLRQLSMSTA
AKLAAGEDPMVEASVVKELGNAFEQDMPRRVQAIVECPWDDPSDLGRLLRALLIASPSFSLRGGTREVIRGIIARGLGLR

Sequences:

>Translated_640_residues
MDDRLIGRAQFQNIAHPAVLRLAQQSLRQPQRARRVADDPLGNGDRAIEQLRIGHHIGNQTIFLCLSRVKAVAGQEQLGR
ARIAEHLLQQPRSAVAGNDTDLDEAARELRAFRCNANVAGAGEVAAKADRMAVDRGDHRHFAIHQRADHRLYAFAIIGSR
RIGLIEHADSGALLHSFEVSAGAERLAAAGQDHRADAAIVAEGAERVDDVLAIVMRADRIHAFGLDHRQDRDLAPPLDTQ
KLAHRQLSFAAPGKLLHGWRDMQGFALYPFDPPGDVAALRAELRAWLAANQPRGDVVARANCWASFDTDFSRKLGAAGYV
GMTLPPRFGGGGRHPLERYVVIEELLAAGAPVGAHWIADRQTGPLILRYGSEEQCQRYLPGIARGELYACIGLSEPGAGS
DLAAVRTTARETAEGWRINGQKIWTTGAHFSHIMLALVRTEAGSERNAGLSQLLIDLDTPGITIRPIIDMADHHDFNEVF
FDDVLVPHGALVGERGQGWRQVTAELGLERSGPERYLSSHALLAALIDAAGVDPDPAVIALIGELVAEMWTLRQLSMSTA
AKLAAGEDPMVEASVVKELGNAFEQDMPRRVQAIVECPWDDPSDLGRLLRALLIASPSFSLRGGTREVIRGIIARGLGLR
>Mature_640_residues
MDDRLIGRAQFQNIAHPAVLRLAQQSLRQPQRARRVADDPLGNGDRAIEQLRIGHHIGNQTIFLCLSRVKAVAGQEQLGR
ARIAEHLLQQPRSAVAGNDTDLDEAARELRAFRCNANVAGAGEVAAKADRMAVDRGDHRHFAIHQRADHRLYAFAIIGSR
RIGLIEHADSGALLHSFEVSAGAERLAAAGQDHRADAAIVAEGAERVDDVLAIVMRADRIHAFGLDHRQDRDLAPPLDTQ
KLAHRQLSFAAPGKLLHGWRDMQGFALYPFDPPGDVAALRAELRAWLAANQPRGDVVARANCWASFDTDFSRKLGAAGYV
GMTLPPRFGGGGRHPLERYVVIEELLAAGAPVGAHWIADRQTGPLILRYGSEEQCQRYLPGIARGELYACIGLSEPGAGS
DLAAVRTTARETAEGWRINGQKIWTTGAHFSHIMLALVRTEAGSERNAGLSQLLIDLDTPGITIRPIIDMADHHDFNEVF
FDDVLVPHGALVGERGQGWRQVTAELGLERSGPERYLSSHALLAALIDAAGVDPDPAVIALIGELVAEMWTLRQLSMSTA
AKLAAGEDPMVEASVVKELGNAFEQDMPRRVQAIVECPWDDPSDLGRLLRALLIASPSFSLRGGTREVIRGIIARGLGLR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=215, Percent_Identity=31.1627906976744, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI226958412, Length=223, Percent_Identity=27.3542600896861, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI226958414, Length=206, Percent_Identity=28.1553398058252, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI4501857, Length=247, Percent_Identity=26.7206477732794, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI7656849, Length=196, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI4501859, Length=198, Percent_Identity=30.8080808080808, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI4557235, Length=341, Percent_Identity=26.6862170087977, Blast_Score=84, Evalue=6e-16,
Organism=Homo sapiens, GI76496475, Length=341, Percent_Identity=26.6862170087977, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI21361497, Length=197, Percent_Identity=28.9340101522843, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI4557231, Length=189, Percent_Identity=29.6296296296296, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI187960098, Length=189, Percent_Identity=29.6296296296296, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI7669494, Length=99, Percent_Identity=38.3838383838384, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI4503943, Length=99, Percent_Identity=38.3838383838384, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI38505218, Length=156, Percent_Identity=31.4102564102564, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI211971008, Length=152, Percent_Identity=33.5526315789474, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI48976061, Length=152, Percent_Identity=33.5526315789474, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI87081958, Length=234, Percent_Identity=29.0598290598291, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1786223, Length=204, Percent_Identity=25, Blast_Score=66, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17538396, Length=399, Percent_Identity=25.8145363408521, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17508101, Length=199, Percent_Identity=32.1608040201005, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71990804, Length=204, Percent_Identity=29.9019607843137, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17534899, Length=197, Percent_Identity=29.4416243654822, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17551932, Length=204, Percent_Identity=29.9019607843137, Blast_Score=89, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17570075, Length=389, Percent_Identity=24.1645244215938, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17506239, Length=187, Percent_Identity=29.9465240641711, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17569725, Length=216, Percent_Identity=28.7037037037037, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI32563615, Length=185, Percent_Identity=29.7297297297297, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17505929, Length=204, Percent_Identity=29.9019607843137, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71985184, Length=194, Percent_Identity=29.8969072164948, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71985192, Length=194, Percent_Identity=29.8969072164948, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17533517, Length=200, Percent_Identity=26.5, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71982178, Length=195, Percent_Identity=26.1538461538462, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355753, Length=349, Percent_Identity=25.214899713467, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24666513, Length=241, Percent_Identity=26.5560165975104, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281363737, Length=215, Percent_Identity=29.7674418604651, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21356377, Length=193, Percent_Identity=26.9430051813472, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24660351, Length=142, Percent_Identity=33.0985915492958, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19920834, Length=196, Percent_Identity=30.6122448979592, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24646207, Length=205, Percent_Identity=27.8048780487805, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 69530; Mature: 69530

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00072 ACYL_COA_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDRLIGRAQFQNIAHPAVLRLAQQSLRQPQRARRVADDPLGNGDRAIEQLRIGHHIGNQ
CCCCCCCHHHHHHCCHHHHHHHHHHHHHCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCH
TIFLCLSRVKAVAGQEQLGRARIAEHLLQQPRSAVAGNDTDLDEAARELRAFRCNANVAG
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCC
AGEVAAKADRMAVDRGDHRHFAIHQRADHRLYAFAIIGSRRIGLIEHADSGALLHSFEVS
CCHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEECCCCEEEEEECCCCCEEEEEECC
AGAERLAAAGQDHRADAAIVAEGAERVDDVLAIVMRADRIHAFGLDHRQDRDLAPPLDTQ
CCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCHH
KLAHRQLSFAAPGKLLHGWRDMQGFALYPFDPPGDVAALRAELRAWLAANQPRGDVVARA
HHHHHHHCCCCCHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEC
NCWASFDTDFSRKLGAAGYVGMTLPPRFGGGGRHPLERYVVIEELLAAGAPVGAHWIADR
CCCCCCCCCHHHHCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEECCC
QTGPLILRYGSEEQCQRYLPGIARGELYACIGLSEPGAGSDLAAVRTTARETAEGWRING
CCCCEEEEECCHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEECC
QKIWTTGAHFSHIMLALVRTEAGSERNAGLSQLLIDLDTPGITIRPIIDMADHHDFNEVF
EEEEECCCHHHHHHHHHHHHCCCCCCCCCHHHHEEECCCCCEEEEEEHHHHCCCCHHHHH
FDDVLVPHGALVGERGQGWRQVTAELGLERSGPERYLSSHALLAALIDAAGVDPDPAVIA
HHHHHCCCCCEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LIGELVAEMWTLRQLSMSTAAKLAAGEDPMVEASVVKELGNAFEQDMPRRVQAIVECPWD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DPSDLGRLLRALLIASPSFSLRGGTREVIRGIIARGLGLR
CHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDDRLIGRAQFQNIAHPAVLRLAQQSLRQPQRARRVADDPLGNGDRAIEQLRIGHHIGNQ
CCCCCCCHHHHHHCCHHHHHHHHHHHHHCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCH
TIFLCLSRVKAVAGQEQLGRARIAEHLLQQPRSAVAGNDTDLDEAARELRAFRCNANVAG
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCC
AGEVAAKADRMAVDRGDHRHFAIHQRADHRLYAFAIIGSRRIGLIEHADSGALLHSFEVS
CCHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEECCCCEEEEEECCCCCEEEEEECC
AGAERLAAAGQDHRADAAIVAEGAERVDDVLAIVMRADRIHAFGLDHRQDRDLAPPLDTQ
CCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCHH
KLAHRQLSFAAPGKLLHGWRDMQGFALYPFDPPGDVAALRAELRAWLAANQPRGDVVARA
HHHHHHHCCCCCHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEC
NCWASFDTDFSRKLGAAGYVGMTLPPRFGGGGRHPLERYVVIEELLAAGAPVGAHWIADR
CCCCCCCCCHHHHCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEECCC
QTGPLILRYGSEEQCQRYLPGIARGELYACIGLSEPGAGSDLAAVRTTARETAEGWRING
CCCCEEEEECCHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEECC
QKIWTTGAHFSHIMLALVRTEAGSERNAGLSQLLIDLDTPGITIRPIIDMADHHDFNEVF
EEEEECCCHHHHHHHHHHHHCCCCCCCCCHHHHEEECCCCCEEEEEEHHHHCCCCHHHHH
FDDVLVPHGALVGERGQGWRQVTAELGLERSGPERYLSSHALLAALIDAAGVDPDPAVIA
HHHHHCCCCCEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LIGELVAEMWTLRQLSMSTAAKLAAGEDPMVEASVVKELGNAFEQDMPRRVQAIVECPWD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DPSDLGRLLRALLIASPSFSLRGGTREVIRGIIARGLGLR
CHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]