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The map label for this gene is moaB [H]

Identifier: 103486670

GI number: 103486670

Start: 1221115

End: 1221639

Strand: Reverse

Name: moaB [H]

Synonym: Sala_1182

Alternate gene names: 103486670

Gene position: 1221639-1221115 (Counterclockwise)

Preceding gene: 103486671

Following gene: 103486669

Centisome position: 36.52

GC content: 65.71

Gene sequence:

>525_bases
ATGCCGATTGACGAGAGCCTGCCGCTCAAGCCCGTTCGCATCGCGCTGCTGACGATTTCGGACAGCCGCAGCGCCGCCGA
TGACCGGTCGGGCGACAGGCTCGAGGAACTGCTCACCGGCGCAGGGCATATTCTCGCCGCGCGCGCGCTCATCAAGGACG
AAACCGACCTTATCGTTTCGCGCCTCCACAACTGGATCGACGATCCAGACGTCGACGTCGTCATCACCACCGGCGGCACC
GGCCTGACCGGCCGCGACGTGACGCCCGAGGCGCTGCACCGGCTCGACGGCAAGGATATTCCGGGGTTCGGCGAGCTGTT
TCGCTGGCTCAGCTATCGGACGATCGGCACGTCGACGATCCAGTCGCGCGCCTGCGCCGTCGTCGCGCGCGGCACCTATA
TCTTCGCGCTTCCCGGCTCGACCGGCGCAGTCACCGACGCGTGGGAGGGTATATTGGCGAGCCAGCTCGACAGTCGGCAC
AAGCCCTGCAATTTCGTCGAGTTGATGCCGAGACTGACCGAATAG

Upstream 100 bases:

>100_bases
AAGCCGTCGGACAGCCGCGCGGCGCTGGCGCAGGGCAAATGGCCCCGCTTTCCCGATGGCAAGGATCGCACGCGCCTGAC
CTGGGCTGGAGGCCTCGCCG

Downstream 100 bases:

>100_bases
CAAGTTTGTTCTTTATTTGTTCCAGACGGGCGATTATTCTCTCTCCGTGAAGTCGTCCAAACCCCTCCCTCCCATCGCGG
GTCGCGGCGCGCCAACCAAT

Product: molybdenum cofactor biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MPIDESLPLKPVRIALLTISDSRSAADDRSGDRLEELLTGAGHILAARALIKDETDLIVSRLHNWIDDPDVDVVITTGGT
GLTGRDVTPEALHRLDGKDIPGFGELFRWLSYRTIGTSTIQSRACAVVARGTYIFALPGSTGAVTDAWEGILASQLDSRH
KPCNFVELMPRLTE

Sequences:

>Translated_174_residues
MPIDESLPLKPVRIALLTISDSRSAADDRSGDRLEELLTGAGHILAARALIKDETDLIVSRLHNWIDDPDVDVVITTGGT
GLTGRDVTPEALHRLDGKDIPGFGELFRWLSYRTIGTSTIQSRACAVVARGTYIFALPGSTGAVTDAWEGILASQLDSRH
KPCNFVELMPRLTE
>Mature_173_residues
PIDESLPLKPVRIALLTISDSRSAADDRSGDRLEELLTGAGHILAARALIKDETDLIVSRLHNWIDDPDVDVVITTGGTG
LTGRDVTPEALHRLDGKDIPGFGELFRWLSYRTIGTSTIQSRACAVVARGTYIFALPGSTGAVTDAWEGILASQLDSRHK
PCNFVELMPRLTE

Specific function: Maybe involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT, but has no MPT adenylyl transferase activity [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=148, Percent_Identity=31.7567567567568, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI10880983, Length=148, Percent_Identity=31.7567567567568, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1787000, Length=160, Percent_Identity=50.625, Blast_Score=156, Evalue=9e-40,
Organism=Escherichia coli, GI1786190, Length=148, Percent_Identity=36.4864864864865, Blast_Score=79, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17136978, Length=153, Percent_Identity=34.640522875817, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24638841, Length=153, Percent_Identity=34.640522875817, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR013484
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18893; Mature: 18761

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIDESLPLKPVRIALLTISDSRSAADDRSGDRLEELLTGAGHILAARALIKDETDLIVS
CCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCHHHHHHH
RLHNWIDDPDVDVVITTGGTGLTGRDVTPEALHRLDGKDIPGFGELFRWLSYRTIGTSTI
HHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHH
QSRACAVVARGTYIFALPGSTGAVTDAWEGILASQLDSRHKPCNFVELMPRLTE
HHHHEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
PIDESLPLKPVRIALLTISDSRSAADDRSGDRLEELLTGAGHILAARALIKDETDLIVS
CCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCHHHHHHH
RLHNWIDDPDVDVVITTGGTGLTGRDVTPEALHRLDGKDIPGFGELFRWLSYRTIGTSTI
HHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHH
QSRACAVVARGTYIFALPGSTGAVTDAWEGILASQLDSRHKPCNFVELMPRLTE
HHHHEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]