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The map label for this gene is phoR [H]

Identifier: 103486611

GI number: 103486611

Start: 1160608

End: 1162056

Strand: Reverse

Name: phoR [H]

Synonym: Sala_1123

Alternate gene names: 103486611

Gene position: 1162056-1160608 (Counterclockwise)

Preceding gene: 103486613

Following gene: 103486609

Centisome position: 34.74

GC content: 65.63

Gene sequence:

>1449_bases
ATGGCGGCGCGACGACGCCGCATCATCCCTATCGACCGGATCCGCCGGGACGTCCCTGTTTTCCATGACCGTCGCATAAC
GCAACGACGGAGCGAGGAAAAGCAAAAGACCAGGGGAAGCCTGCTCGTTTCCCGCTTTGATACAAGCCCGGCAAAAGCGT
TAACATGCGCAAAGCCGATTGCGCGCATCCCCCGCTTCGTGCGAAGCGGGCGGCGCATGTTCGATCGCCTGTCCAGCCTT
GTCATCGCGCTGACGCTGATCGCCATTGCGGCGATCTTTGCGGCGCTGGCCGGTGGCGACCCGCCGACGATCGCGATGAT
GGCGGTCGCGGGTTTCGCCGCAACCTTCACGGTTTACAGCGCGCTTCCTCCCGCCCTGTCCGCGACCCGCGCCCAGCGAA
CCTCGCCTGCCGAGACACGTCCGCTTTCCTTGCTGCGTCATCCCGATTTCGCACGCTGGGTCGATCAGGAAAAAGACCCG
CTGCTCGGCGTTGCCGATAATGTCGTCGCCATCGCCAACGACGCGGCCATTCGGCTGCTCGGACGGCACATCGTCGGCGC
CGACATCCGCACCGCGATCCGTCATCCGCTCGCCACCGAATGGCTGTCGCGGATCGACGGCGACGCGCCGCTGGAGACGA
TCGACCTCGTCGATTATCCCCGCCCCGGCCAGCGCTGGACCATGCGCATCGCCGCGCTGTCGAACGGCGAACGCATCGTC
TTCCTGTCCGATCGCTCGGCGATCGACGCCGCCGACCGGATGCGGTCCGATTTTGTCGCCAACGCCAGCCACGAGCTGCG
CACCCCGCTCGCCGCGATCATCGGCTATGTCGAAACATTGCAGGACATGAATGGCGAAGACGACGGCGCAACGCGGCGCC
GCTTCCTGTCGATCATCGAGCGCGAGGCGCGGCGGATGCAGCAACTGGTGATCGACCTGCTCTCAATCTCGCGCGTCGAG
GCCGACCGCTTTCGCCGTCCAACCGCCGAGGTCGACCTCGCCGCGATCGTCCGGCACACGATCACCCAATTGCAGGACAG
CGAATCCGCGCGGCCGAAGGACATTGTCGCGGCGCTCGGCACCGAAGCGATGCCGATGCTGGGCGACGAGGCGCAGCTCG
GCCAACTCGCCCACAATATCATATCCAATGCGTTGAAATATGGCCGTCCCGGCACGCCGGTGACGGTCGAACTGCTGCGC
GAAGGAGCGCGCGTTCGGCTGTCGGTGAGCGACGAGGGTGACGGCATCGCCCCCGACCATATCCCGCGGCTGACCGAACG
CTTTTACCGCGTCGACGAGGCGCGCAGCCGCTCGGTCGGCGGCACCGGTCTTGGCCTCGCGATCGTCAAGCATATCAGCG
AGCGCCATCAGGGGCAGCTCCACATCGACAGCGAACCGGGCAAGGGAACCAGCGTTTCGATAAGCTTTCCCCTTGCCGCC
AGCGCCTAA

Upstream 100 bases:

>100_bases
GCACCGGAATCTGGCAGTTCATCACCGACACCGCGGTCTGGGCAAAGGCGGGCCGGATCGTCAGCGCCGCCGATACGCCC
GCCGCGCCAAGCGCGAGCAC

Downstream 100 bases:

>100_bases
TCGATCCGGTCGATGAGGTCGGCGATCGTCCCGAACATTGCGTCGATTTGTTCCTTCTCGACGATCAGCGGCGGCGACAG
CGCGATGATATCGCCCGTAG

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MAARRRRIIPIDRIRRDVPVFHDRRITQRRSEEKQKTRGSLLVSRFDTSPAKALTCAKPIARIPRFVRSGRRMFDRLSSL
VIALTLIAIAAIFAALAGGDPPTIAMMAVAGFAATFTVYSALPPALSATRAQRTSPAETRPLSLLRHPDFARWVDQEKDP
LLGVADNVVAIANDAAIRLLGRHIVGADIRTAIRHPLATEWLSRIDGDAPLETIDLVDYPRPGQRWTMRIAALSNGERIV
FLSDRSAIDAADRMRSDFVANASHELRTPLAAIIGYVETLQDMNGEDDGATRRRFLSIIEREARRMQQLVIDLLSISRVE
ADRFRRPTAEVDLAAIVRHTITQLQDSESARPKDIVAALGTEAMPMLGDEAQLGQLAHNIISNALKYGRPGTPVTVELLR
EGARVRLSVSDEGDGIAPDHIPRLTERFYRVDEARSRSVGGTGLGLAIVKHISERHQGQLHIDSEPGKGTSVSISFPLAA
SA

Sequences:

>Translated_482_residues
MAARRRRIIPIDRIRRDVPVFHDRRITQRRSEEKQKTRGSLLVSRFDTSPAKALTCAKPIARIPRFVRSGRRMFDRLSSL
VIALTLIAIAAIFAALAGGDPPTIAMMAVAGFAATFTVYSALPPALSATRAQRTSPAETRPLSLLRHPDFARWVDQEKDP
LLGVADNVVAIANDAAIRLLGRHIVGADIRTAIRHPLATEWLSRIDGDAPLETIDLVDYPRPGQRWTMRIAALSNGERIV
FLSDRSAIDAADRMRSDFVANASHELRTPLAAIIGYVETLQDMNGEDDGATRRRFLSIIEREARRMQQLVIDLLSISRVE
ADRFRRPTAEVDLAAIVRHTITQLQDSESARPKDIVAALGTEAMPMLGDEAQLGQLAHNIISNALKYGRPGTPVTVELLR
EGARVRLSVSDEGDGIAPDHIPRLTERFYRVDEARSRSVGGTGLGLAIVKHISERHQGQLHIDSEPGKGTSVSISFPLAA
SA
>Mature_481_residues
AARRRRIIPIDRIRRDVPVFHDRRITQRRSEEKQKTRGSLLVSRFDTSPAKALTCAKPIARIPRFVRSGRRMFDRLSSLV
IALTLIAIAAIFAALAGGDPPTIAMMAVAGFAATFTVYSALPPALSATRAQRTSPAETRPLSLLRHPDFARWVDQEKDPL
LGVADNVVAIANDAAIRLLGRHIVGADIRTAIRHPLATEWLSRIDGDAPLETIDLVDYPRPGQRWTMRIAALSNGERIVF
LSDRSAIDAADRMRSDFVANASHELRTPLAAIIGYVETLQDMNGEDDGATRRRFLSIIEREARRMQQLVIDLLSISRVEA
DRFRRPTAEVDLAAIVRHTITQLQDSESARPKDIVAALGTEAMPMLGDEAQLGQLAHNIISNALKYGRPGTPVTVELLRE
GARVRLSVSDEGDGIAPDHIPRLTERFYRVDEARSRSVGGTGLGLAIVKHISERHQGQLHIDSEPGKGTSVSISFPLAAS
A

Specific function: Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=292, Percent_Identity=35.2739726027397, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1788393, Length=237, Percent_Identity=31.2236286919831, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI145693157, Length=245, Percent_Identity=27.7551020408163, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1789149, Length=262, Percent_Identity=29.3893129770992, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87082128, Length=244, Percent_Identity=29.5081967213115, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790346, Length=238, Percent_Identity=29.4117647058824, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1786783, Length=233, Percent_Identity=29.1845493562232, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788713, Length=234, Percent_Identity=26.4957264957265, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI48994928, Length=294, Percent_Identity=26.1904761904762, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787894, Length=241, Percent_Identity=29.4605809128631, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788549, Length=258, Percent_Identity=25.968992248062, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790436, Length=228, Percent_Identity=27.1929824561404, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1789403, Length=219, Percent_Identity=27.8538812785388, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786912, Length=226, Percent_Identity=25.6637168141593, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789808, Length=224, Percent_Identity=29.9107142857143, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87081816, Length=241, Percent_Identity=26.9709543568465, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790861, Length=219, Percent_Identity=30.1369863013699, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790551, Length=208, Percent_Identity=27.8846153846154, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR021766
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014310 [H]

Pfam domain/function: PF11808 DUF3329; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53018; Mature: 52886

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARRRRIIPIDRIRRDVPVFHDRRITQRRSEEKQKTRGSLLVSRFDTSPAKALTCAKPI
CCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ARIPRFVRSGRRMFDRLSSLVIALTLIAIAAIFAALAGGDPPTIAMMAVAGFAATFTVYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ALPPALSATRAQRTSPAETRPLSLLRHPDFARWVDQEKDPLLGVADNVVAIANDAAIRLL
HCCCHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHCCCCCCCCCCCCCEEEEECHHHHHHH
GRHIVGADIRTAIRHPLATEWLSRIDGDAPLETIDLVDYPRPGQRWTMRIAALSNGERIV
HHHHHCHHHHHHHHCCHHHHHHHHCCCCCCCCEEECCCCCCCCCHHEEEEEEECCCCEEE
FLSDRSAIDAADRMRSDFVANASHELRTPLAAIIGYVETLQDMNGEDDGATRRRFLSIIE
EECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
REARRMQQLVIDLLSISRVEADRFRRPTAEVDLAAIVRHTITQLQDSESARPKDIVAALG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
TEAMPMLGDEAQLGQLAHNIISNALKYGRPGTPVTVELLREGARVRLSVSDEGDGIAPDH
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHCCCEEEEEECCCCCCCCCHH
IPRLTERFYRVDEARSRSVGGTGLGLAIVKHISERHQGQLHIDSEPGKGTSVSISFPLAA
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCC
SA
CC
>Mature Secondary Structure 
AARRRRIIPIDRIRRDVPVFHDRRITQRRSEEKQKTRGSLLVSRFDTSPAKALTCAKPI
CCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ARIPRFVRSGRRMFDRLSSLVIALTLIAIAAIFAALAGGDPPTIAMMAVAGFAATFTVYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ALPPALSATRAQRTSPAETRPLSLLRHPDFARWVDQEKDPLLGVADNVVAIANDAAIRLL
HCCCHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHCCCCCCCCCCCCCEEEEECHHHHHHH
GRHIVGADIRTAIRHPLATEWLSRIDGDAPLETIDLVDYPRPGQRWTMRIAALSNGERIV
HHHHHCHHHHHHHHCCHHHHHHHHCCCCCCCCEEECCCCCCCCCHHEEEEEEECCCCEEE
FLSDRSAIDAADRMRSDFVANASHELRTPLAAIIGYVETLQDMNGEDDGATRRRFLSIIE
EECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
REARRMQQLVIDLLSISRVEADRFRRPTAEVDLAAIVRHTITQLQDSESARPKDIVAALG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
TEAMPMLGDEAQLGQLAHNIISNALKYGRPGTPVTVELLREGARVRLSVSDEGDGIAPDH
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHCCCEEEEEECCCCCCCCCHH
IPRLTERFYRVDEARSRSVGGTGLGLAIVKHISERHQGQLHIDSEPGKGTSVSISFPLAA
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCC
SA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2556368 [H]