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The map label for this gene is rsmB [H]

Identifier: 103486536

GI number: 103486536

Start: 1080233

End: 1081546

Strand: Reverse

Name: rsmB [H]

Synonym: Sala_1047

Alternate gene names: 103486536

Gene position: 1081546-1080233 (Counterclockwise)

Preceding gene: 103486537

Following gene: 103486535

Centisome position: 32.33

GC content: 71.77

Gene sequence:

>1314_bases
ATGCCACGGCCCGTCATGGCTGATCGCCGTTCCTCCCGGAGGCGACCGCGCGGCGAGGCCGATCCGCCGGGCCTCGCGCC
GCGCCGCGCCGCGCTGCGCCTGCTCGACGCGATCGTGCGCCGCGGCGACCCGCTCGACGTTGCAATGCACGCCGCGGCGC
AAGGGCTGGTCGGCGCCGACCGTGCCTTTGCCGTCGCCATCGCGTCCGAAGCGCTGCGCTGGATGACCGACATCGACGCG
CTGGTCGACGGCGCGACCGCGCAGCCGTTGCCCGACGATGTCAAATCGCGCGCGGTGCTCAGGATCGCACTCGCGCAGTT
GCTCGTGCTCAAAAGCCCCGGCCACGCCGTGGTCGCGACTGCGCTTCCCCTCGTCGATGGCGGCCCGCGGCGTCTTGTCC
ACGCGATCCTGTCGCGTGCACAGAAGGAAAAGTGGGAACTGCCGGCGCGTGCGTCCTTGCCGCCCGCCGCGGCAGAGCGC
TGGACCGCGCAATGGGGCGCCACGATGATCGAAGCCGCCGCCGAAAGCTGGAGCGTCCCGCCACCGATCGACCTCAGCTT
CGCTGCCGAACCCGCCCCCGACGAATGGCCCGATGCCGTCGCCCTCGCACCGCGCCACCGCCGCCTTCCGCGCGGGCAGG
CGGTCGAGGCGATGCCGGGTTTCGCCGAAGGCGGCTGGTGGGTGCAGGATCTCGCCGCCAGCCTGCCCGCGCGCCTTCTC
GGCGCGGGCGCCGGGCGGACCATTCTCGACCTTTGCGCGGCGCCCGGCGGCAAGACGATGCAGCTCGCCGCCGCCAACTG
GGCGGTCACCGCGGTCGACTCGAGCGCCAGGCGCCTCGAGCGGCTGCGCGCCAACCTCACGCGCACCGGCCTTGCCGCCA
CAATCGTGCAAGGCGACATCCGCACATGGGAACCCGATGCCGCGGCCGATGCCGTGCTGCTCGACGCCCCCTGTTCGGCG
ACGGGCATTTTCCGCCGCCATCCCGACGTGATCCACCGCATCGAGCCGCGACAAATCGAAGAAATGGCAACGTTACAGGC
CGGATTGCTAGCGCGCGCCGCGAAATGGGTCAAACCCGGCGGCACACTCGTCTACGCGACCTGCTCGCTCGAACGCGCCG
AGGGCGAGGATCAGGTCGCGGCCTTTCTCGACGCGCATCGCGGCTGGGCGATTGACGCGGCGCGACCCGACGAACTGGCA
ACGGGCATCACCCCCGACATCAACGGCTGCGTCCGTACGCTCCCCGGCCAGATCGCCGACGCGGGCGGACTCGACGGCTT
CTTCATCGCCCGCCTTCGTGCGCCAGACGCTTGA

Upstream 100 bases:

>100_bases
CGGCGGGCGCTTTACAGCGCGCGGGGTTCCGCCGATGGTCGCCTCTTCGCTCTTGTCGGTCATGCCCGTCCTATAGGATC
ATTGATGCGTCTCGCCAACC

Downstream 100 bases:

>100_bases
TCGCGCCATCCGACGGTTTCCGCCCGAACGCTTGGCAGCGCTGACATCTGGACAGCCGCGAAAAGCCGTTTAGAGCGGCG
TGCCGTATATCTGATTCACC

Product: Fmu (Sun)

Products: NA

Alternate protein names: 16S rRNA m5C967 methyltransferase; rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MPRPVMADRRSSRRRPRGEADPPGLAPRRAALRLLDAIVRRGDPLDVAMHAAAQGLVGADRAFAVAIASEALRWMTDIDA
LVDGATAQPLPDDVKSRAVLRIALAQLLVLKSPGHAVVATALPLVDGGPRRLVHAILSRAQKEKWELPARASLPPAAAER
WTAQWGATMIEAAAESWSVPPPIDLSFAAEPAPDEWPDAVALAPRHRRLPRGQAVEAMPGFAEGGWWVQDLAASLPARLL
GAGAGRTILDLCAAPGGKTMQLAAANWAVTAVDSSARRLERLRANLTRTGLAATIVQGDIRTWEPDAAADAVLLDAPCSA
TGIFRRHPDVIHRIEPRQIEEMATLQAGLLARAAKWVKPGGTLVYATCSLERAEGEDQVAAFLDAHRGWAIDAARPDELA
TGITPDINGCVRTLPGQIADAGGLDGFFIARLRAPDA

Sequences:

>Translated_437_residues
MPRPVMADRRSSRRRPRGEADPPGLAPRRAALRLLDAIVRRGDPLDVAMHAAAQGLVGADRAFAVAIASEALRWMTDIDA
LVDGATAQPLPDDVKSRAVLRIALAQLLVLKSPGHAVVATALPLVDGGPRRLVHAILSRAQKEKWELPARASLPPAAAER
WTAQWGATMIEAAAESWSVPPPIDLSFAAEPAPDEWPDAVALAPRHRRLPRGQAVEAMPGFAEGGWWVQDLAASLPARLL
GAGAGRTILDLCAAPGGKTMQLAAANWAVTAVDSSARRLERLRANLTRTGLAATIVQGDIRTWEPDAAADAVLLDAPCSA
TGIFRRHPDVIHRIEPRQIEEMATLQAGLLARAAKWVKPGGTLVYATCSLERAEGEDQVAAFLDAHRGWAIDAARPDELA
TGITPDINGCVRTLPGQIADAGGLDGFFIARLRAPDA
>Mature_436_residues
PRPVMADRRSSRRRPRGEADPPGLAPRRAALRLLDAIVRRGDPLDVAMHAAAQGLVGADRAFAVAIASEALRWMTDIDAL
VDGATAQPLPDDVKSRAVLRIALAQLLVLKSPGHAVVATALPLVDGGPRRLVHAILSRAQKEKWELPARASLPPAAAERW
TAQWGATMIEAAAESWSVPPPIDLSFAAEPAPDEWPDAVALAPRHRRLPRGQAVEAMPGFAEGGWWVQDLAASLPARLLG
AGAGRTILDLCAAPGGKTMQLAAANWAVTAVDSSARRLERLRANLTRTGLAATIVQGDIRTWEPDAAADAVLLDAPCSAT
GIFRRHPDVIHRIEPRQIEEMATLQAGLLARAAKWVKPGGTLVYATCSLERAEGEDQVAAFLDAHRGWAIDAARPDELAT
GITPDINGCVRTLPGQIADAGGLDGFFIARLRAPDA

Specific function: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=237, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI76150623, Length=237, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI32698918, Length=178, Percent_Identity=32.0224719101124, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI40316918, Length=168, Percent_Identity=33.9285714285714, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI11545785, Length=179, Percent_Identity=32.4022346368715, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI23199998, Length=243, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI270288818, Length=243, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI8922322, Length=243, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI270288816, Length=249, Percent_Identity=29.3172690763052, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI2367212, Length=448, Percent_Identity=32.5892857142857, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI87081985, Length=239, Percent_Identity=34.3096234309623, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17536757, Length=273, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17509941, Length=159, Percent_Identity=31.4465408805031, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71998419, Length=242, Percent_Identity=28.9256198347107, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115534021, Length=170, Percent_Identity=32.9411764705882, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324268, Length=235, Percent_Identity=31.9148936170213, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319447, Length=241, Percent_Identity=28.6307053941909, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI22024126, Length=245, Percent_Identity=28.9795918367347, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI19920494, Length=159, Percent_Identity=30.188679245283, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24668781, Length=235, Percent_Identity=29.3617021276596, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI21356513, Length=235, Percent_Identity=29.3617021276596, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355201, Length=176, Percent_Identity=30.1136363636364, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: =2.1.1.176 [H]

Molecular weight: Translated: 46422; Mature: 46290

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPVMADRRSSRRRPRGEADPPGLAPRRAALRLLDAIVRRGDPLDVAMHAAAQGLVGAD
CCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
RAFAVAIASEALRWMTDIDALVDGATAQPLPDDVKSRAVLRIALAQLLVLKSPGHAVVAT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
ALPLVDGGPRRLVHAILSRAQKEKWELPARASLPPAAAERWTAQWGATMIEAAAESWSVP
HHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
PPIDLSFAAEPAPDEWPDAVALAPRHRRLPRGQAVEAMPGFAEGGWWVQDLAASLPARLL
CCCCCCCCCCCCCCCCCCCEEECCHHHCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHH
GAGAGRTILDLCAAPGGKTMQLAAANWAVTAVDSSARRLERLRANLTRTGLAATIVQGDI
CCCCCHHHHHHHCCCCCCEEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHEEEECCC
RTWEPDAAADAVLLDAPCSATGIFRRHPDVIHRIEPRQIEEMATLQAGLLARAAKWVKPG
CCCCCCCCCCEEEEECCCCCCHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
GTLVYATCSLERAEGEDQVAAFLDAHRGWAIDAARPDELATGITPDINGCVRTLPGQIAD
CEEEEEEEECCCCCCHHHHHHHHHHCCCEEECCCCCHHHHCCCCCCCCHHHHHCCCHHCC
AGGLDGFFIARLRAPDA
CCCCCCEEEEEECCCCC
>Mature Secondary Structure 
PRPVMADRRSSRRRPRGEADPPGLAPRRAALRLLDAIVRRGDPLDVAMHAAAQGLVGAD
CCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
RAFAVAIASEALRWMTDIDALVDGATAQPLPDDVKSRAVLRIALAQLLVLKSPGHAVVAT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
ALPLVDGGPRRLVHAILSRAQKEKWELPARASLPPAAAERWTAQWGATMIEAAAESWSVP
HHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
PPIDLSFAAEPAPDEWPDAVALAPRHRRLPRGQAVEAMPGFAEGGWWVQDLAASLPARLL
CCCCCCCCCCCCCCCCCCCEEECCHHHCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHH
GAGAGRTILDLCAAPGGKTMQLAAANWAVTAVDSSARRLERLRANLTRTGLAATIVQGDI
CCCCCHHHHHHHCCCCCCEEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHEEEECCC
RTWEPDAAADAVLLDAPCSATGIFRRHPDVIHRIEPRQIEEMATLQAGLLARAAKWVKPG
CCCCCCCCCCEEEEECCCCCCHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
GTLVYATCSLERAEGEDQVAAFLDAHRGWAIDAARPDELATGITPDINGCVRTLPGQIAD
CEEEEEEEECCCCCCHHHHHHHHHHCCCEEECCCCCHHHHCCCCCCCCHHHHHCCCHHCC
AGGLDGFFIARLRAPDA
CCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA